Preclinical efficacy of sodium narcistatin to reduce inflammation and joint destruction in rats with adjuvant-induced arthritis

Rheumatology International

Volumn 32, Issue 12, 2012, Pages 3751-3760

  Lubahn, Cheri ^a   Schaller, Jill A ^a   Shewmacker, Eric ^a   Wood, Carlo ^b   Bellinger, Denise L ^b   Byron, Donna ^c   Melody, Noeleen ^d   Pettit, George R ^d   Lorton, Dianne ^e,f  

^a SUN HEALTH RESEARCH INSTITUTE   (United States)

^b LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Banner Del E Web Medical Center   (United States)

^d ARIZONA STATE UNIVERSITY   (United States)

^e KENT STATE UNIVERSITY   (United States)

^f SUMMA HEALTH SYSTEM   (United States)

Author keywords

Adjuvant induced arthritis; Bone destruction; Cytokines; InXammation; Rheumatoid arthritis; Sodium narcistatin

Indexed keywords

ANTIRHEUMATIC AGENT; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; PRODRUG; SODIUM NARCISTATIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADJUVANT ARTHRITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG EFFICACY; DRUG STRUCTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; MALE; NONHUMAN; OSTEOLYSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RAT; SCORING SYSTEM; SPLEEN CELL; TH1 CELL; TH2 CELL;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, EXPERIMENTAL; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; INFLAMMATION; JOINTS; MALE; ORGANOPHOSPHORUS COMPOUNDS; RATS; RATS, INBRED LEW; TREATMENT OUTCOME;

EID: 84872277929     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-011-2217-z     Document Type: Article

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