Efficacy of modified minimally invasive surgical technique in the treatment of human intrabony defects with or without use of rhPDGF-BB gel - A randomized controlled trial

Journal of Clinical Periodontology

Volumn 40, Issue 2, 2013, Pages 172-179

  Mishra, Ashank ^a   Avula, Haritha ^a   Pathakota, Krishnajaneya R ^a   Avula, Jayakumar ^a  

^a SRI SAI COLLEGE OF DENTAL SURGERY   (India)

Author keywords

intrabony defects; M MIST; rhPDGF BB

Indexed keywords

PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR BB; PLATELET-DERIVED GROWTH FACTOR BB; RECOMBINANT PROTEIN;

ADULT; ALVEOLAR BONE LOSS; ANALYSIS OF VARIANCE; ARTICLE; CHRONIC PERIODONTITIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; GEL; GINGIVA DISEASE; HUMAN; MALE; METHODOLOGY; MIDDLE AGED; MINIMALLY INVASIVE SURGERY; ORAL SURGERY; PERIODONTICS; POSTOPERATIVE CARE; RADIOGRAPHY; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

ADULT; ALVEOLAR BONE LOSS; ANALYSIS OF VARIANCE; CHRONIC PERIODONTITIS; DOUBLE-BLIND METHOD; FEMALE; GELS; GINGIVAL RECESSION; HUMANS; MALE; MIDDLE AGED; ORAL SURGICAL PROCEDURES; PERIODONTAL INDEX; POSTOPERATIVE CARE; PROTO-ONCOGENE PROTEINS C-SIS; RECOMBINANT PROTEINS; SURGICAL PROCEDURES, MINIMALLY INVASIVE; TREATMENT OUTCOME;

EID: 84872273384     PISSN: 03036979     EISSN: 1600051X     Source Type: Journal    
DOI: 10.1111/jcpe.12030     Document Type: Article

References (42)

1. Armitage, G. C., (1999) Development of a classification system for periodontal diseases and conditions. Annals of Periodontology 4, 1-6.
2. Camelo, M., Nevins, M. L., Schenk, R. K., Lynch, S. E., &, Nevins, M., (2003) Periodontal regeneration in human Class II furcations using purified recombinant human platelet-derived growth factor-BB (rhPDGF-BB) with bone allograft. The International Journal of Periodontics & Restorative Dentistry 23, 213-225.
3. Cortellini, P., Nieri, M., Prato, G. P., &, Tonetti, M. S., (2008) Single minimally invasive surgical technique with an enamel matrix derivative to treat multiple adjacent intra-bony defects: clinical outcomes and patient morbidity. Journal of Clinical Periodontology 35, 605-613.
4. Cortellini, P., Pini Prato, G., &, Tonetti, M. S., (1993) Periodontal regeneration of human infrabony defects. I. Clinical measures. Journal of Periodontology 64, 254-260.
5. Cortellini, P., &, Tonetti, M. S., (2007a) A minimally invasive surgical technique with an enamel matrix derivative in the regenerative treatment of intra-bony defects: A novel approach to limit morbidity. Journal of Clinical Periodontology 34, 87-93.
6. Cortellini, P., &, Tonetti, M. S., (2007b) Minimally invasive surgical technique and enamel matrix derivative in intra-bony defects. I: Clinical outcomes and morbidity. Journal of Clinical Periodontology 34, 1082-1088.
7. Cortellini, P., &, Tonetti, M. S., (2009) Improved wound stability with a modified minimally invasive surgical technique in the regenerative treatment of isolated interdental intrabony defects. Journal of Clinical Periodontology 36, 157-163.
8. Cortellini, P., &, Tonetti, M. S., (2011) Clinical and radiographic outcomes of the modified minimally invasive surgical technique with and without regenerative materials: A randomized-controlled trial in intra-bony defects. Journal of Clinical Periodontology 38, 365-373.
9. Eickholz, P., Horr, T., Klein, F., Hassfeld, S., &, Kim, T., (2004) Radiographic parameters for prognosis of periodontal healing of infrabony defects. Two different definitions of defect depth. Journal of Periodontology 75, 399-407.
10. Fickl, S., Thalmair, T., Kebschull, M., Bohm, S., &, Wachtel, H., (2009) Microsurgical access flap in conjunction with enamel matrix derivative for the treatment of intra-bony defects: A controlled clinical trial. Journal of Clinical Periodontology 36, 784-790.
11. Glickman, I., (1953) Clinical Periodontology. Philadelphia: Saunders.
12. Gutierrez, M. A., Mellonig, J. T., &, Cochran, D. L., (2003) Evaluation of enamel matrix derivative as an adjunct to non-surgical periodontal therapy. Journal of Clinical Periodontology 30, 739-745.
13. Harrel, S. K., &, Rees, T. D., (1995) Granulation tissue removal in routine and minimally invasive procedures. Compendium of Continuing Education in Dentistry 16, 960-967.
14. Hegde, R., Sumanth, S., &, Padhye, A., (2009) Microscope-enhanced periodontal therapy: A review and report of four cases. The Journal of Contemporary Dental Practice 10, E088-E096.
15. Howell, T. H., Fiorellini, J. P., Paquette, D. W., Offenbacher, S., Giannobile, W. V., &, Lynch, S. E., (1997) A phase I/II clinical trial to evaluate a combination of recombinant human platelet-derived growth factor-BB and recombinant human insulin-like growth factor-I in patients with periodontal disease. Journal of Periodontology 68, 1186-1193.
16. Hunt, D. R., Jovanovic, S. A., Wikesjo, U. M., Wozney, J. M., &, Bernard, G. W., (2001) Hyaluronan supports recombinant human bone morphogenetic protein-2 induced bone reconstruction of advanced alveolar ridge defects in dogs. A pilot study. Journal of Periodontology 72, 651-658.
17. Jayakumar, A., Rajababu, P., Rohini, S., Butchibabu, K., Naveen, A., Reddy, P. K., Vidyasagar, S., Satyanarayana, D., &, Pavan Kumar, S., (2011) Multi-centre, randomized clinical trial on efficacy and safety of recombinant human platelet-derived growth factor with β-tricalcium phosphate in human intra-osseous periodontal defects. Journal of Clinical Periodontology 38, 163-172.
18. Kao, R. T., &, Lynch, S. E., (2011) Stability of recombinant human platelet derived growth factor-BB regenerated periodontal defects: Sixty-month clinical and radiographic observations. Clinical Advances in Periodontics 1, 132-141.
19. Kwon, H.-R., Wikesjo, U. M. E., Park, J.-C., Kim, Y.-T., Bastone, P., Pippig, S. D., &, Kim, C.-K., (2010) Growth/differentiation factor-5 significantly enhances periodontal wound healing/regeneration compared with platelet-derived growth factor-BB in dogs. Journal of Clinical Periodontology 37, 739-746.
20. Laurell, L., (1995) Guided tissue regeneration in clinical studies: a review. In:, Hugoson, A., &, Lundgren, B., (eds). Guided periodontal tissue regeneration, (pp. 68-90). Sweden, Institute for postgraduate dental education: Jonkoping.
21. Laurell, L., Gottlow, J., Zybutz, M., &, Persson, R., (1998) Treatment of intrabony defects by different surgical procedures. A literature review. Journal of Periodontology 69, 303-313.
22. Lobene, R. R., Weatherford, T., Ross, N. M., Lamm, R. A., &, Menaker, L., (1986) A modified gingival index for use in clinical trials. Clinical Preventive Dentistry 8, 3-6.
23. Matsuda, N., Lin, W. L., Kumar, N. M., Cho, M. I., &, Genco, R. J., (1992) Mitogenic, chemotactic, and synthetic responses of rat periodontal ligament fibroblastic cells to polypeptide growth factors in vitro. Journal of Periodontology 63, 515-525.
24. Mellonig, J. T., (1984) Decalcified freeze-dried bone allograft as an implant material in human periodontal defects. The International Journal of Periodontics and Restorative Dentistry 4, 40-55.
25. Miller, S. C., (1943) Textbook of Periodontia (Oral Medicine) 2nd edition, (p. 103). Philadelphia: The BlakistonCo.
26. Mombelli, A., Brochut, P., Plagnat, D., Casagni, F., &, Giannopoulou, C., (2005) Enamel matrix proteins and systemic antibiotics as adjuncts to non-surgical periodontal treatment: clinical effects. Journal of Clinical Periodontology 32 (3), 225-30.
27. Nevins, M., Camelo, M., Nevins, M. L., Schenk, R. K., &, Lynch, S. E., (2003) Periodontal regeneration in humans using recombinant human platelet-derived growth factor-BB (rhPDGF-BB) and allogenic bone. Journal of Periodontology 74, 1282-1292.
28. Nevins, M., Giannobile, W. V., McGuire, M. K., Kao, R. T., Mellonig, J. T., Hinrichs, J. E., McAllister, B. S., Murphy, K. S., McClain, P. K., Nevins, M. L., Paquette, D. W., Han, T. J., Reddy, M. S., Lavin, P. T., Genco, R. J., &, Lynch, S. E., (2005) Platelet-derived growth factor stimulates bone fill and rate of attachment level gain: results of a large multicenter randomized controlled trial. Journal of Periodontology 76, 2205-2215.
29. O'Leary, T. J., Drake, R. B., &, Naylor, J. E., (1972) The plaque control record. Journal of Periodontology 43, 48.
30. Park, J. B., Matsuura, M., Han, K. Y., Norderyd, O., Lin, W. L., Genco, R. J., &, Cho, M. I., (1995) Periodontal regeneration in class III furcation defects of beagle dogs using guided tissue regenerative therapy with platelet-derived growth factor. Journal of Periodontology 66, 462-477.
31. Renvert, S., Badersten, A., Nilveus, R., &, Egelberg, J., (1981) Healing after treatment of periodontal intraosseous defects I. Comparative study of clinical methods. Journal of Clinical Periodontology 8, 387-399.
32. Renvert, S., &, Egelberg, J., (1981) Healing after treatment of periodontal intraosseous defects: II. Effect of citric acid conditioning of the root surface. Journal of Clinical Periodontology 8, 459-473.
33. Ribeiro, F. V., Casarin, R. C., Palma, M. A., Junior, F. H., Sallum, E. A., &, Casati, M. Z., (2011a) Clinical and patient-centered outcomes after minimally invasive non-surgical or surgical approaches for the treatment of intrabony defects: A randomized clinical trial. Journal of Periodontology 82, 1256-1266.
34. Ribeiro, F. V., Casarin, R. C. V., Francisco, H. N. Jr, Sallum, E. A., &, Casati, M. Z., (2011b) The role of Enamel matrix derivative protein in minimally invasive surgery in treating intrabony defects in single-rooted teeth: A randomized clinical trial. Journal of Periodontology 82, 522-532.
35. Schei, O., Waerhaug, J., Lovdal, A., &, Arno, A., (1959) Alveolar bone loss as related to oral hygiene and age. Journal of Periodontology 30, 7-16.
36. Shirakata, Y., Taniyama, K., Yoshimoto, T., Miyamoto, M., Takeuchi, N., Matsuyama, T., &, Noguchi, K., (2010) Regenerative effect of basic fibroblast growth factor on periodontal healing in two-wall intrabony defects in dogs. Journal of Clinical Periodontology 37, 374-381.
37. Solchaga, L. A., Dennis, J. E., Goldberg, V. M., &, Caplan, A. I., (1999) Hyaluronic acid-based polymers as cell carriers for tissue-engineered repair of bone and cartilage. Journal of Orthopaedic Reaearch 17, 205-213.
38. Tonetti, M. S., Lang, N. P., Cortellini, P., Suvan, J. E., Adriaens, P., Dubravec, D., Fonzar, A., Fourmousis, I., Mayfield, L., Rossi, R., Silvestri, M., Tiedemann, C., Topoll, H., Vangsted, T., &, Wallkamm, B., (2002) Enamel matrix proteins in the regenerative therapy of deep intrabony defects. Journal of Clinical Periodontology 29 (4), 317-25.
39. Tsitoura, E., Tucker, R., Suvan, J., Laurell, L., Cortellini, P., &, Tonetti, M., (2004) Baseline radiographic defect angle of the intrabony defect as a prognostic indicator in regenerative periodontal surgery with enamel matrix derivative. Journal of Clinical Periodontology 31 (8), 643-7.
40. Yukna, R. A., (1990) HTR polymer grafts in human periodontal osseous defects. I. 6-month clinical results. Journal of Periodontology 61, 633-642.
41. Yukna, R. A., (1994) Clinical evaluation of coralline calcium carbonate as a bone replacement graft material in human periodontal osseous defects. Journal of Periodontology 65, 177-185.
42. Zadeh, H. H., &, Daftary, F., (2004) Minimally invasive surgery: an alternative approach for periodontal and implant reconstruction. Journal of the California Dental Association 32, 1022-1030.