-
1
-
-
34250002745
-
Physiological functions of d-amino acid oxidases: from yeast to humans
-
Pollegioni L., Piubelli L., Sacchi S., Pilone M.S., Molla G. Physiological functions of d-amino acid oxidases: from yeast to humans. Cell. Mol. Life Sci. 2007, 64:1373-1394.
-
(2007)
Cell. Mol. Life Sci.
, vol.64
, pp. 1373-1394
-
-
Pollegioni, L.1
Piubelli, L.2
Sacchi, S.3
Pilone, M.S.4
Molla, G.5
-
2
-
-
0034712857
-
D-Serine is an endogenous ligand for the glycine site of the N-methyl-d-aspartate receptor
-
Mothet J.P., Parent A.T., Wolosker H., Brady R.O., Linden D.J., Ferris C.D., Rogawski M.A., Snyder S.H. d-Serine is an endogenous ligand for the glycine site of the N-methyl-d-aspartate receptor. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:4926-4931.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 4926-4931
-
-
Mothet, J.P.1
Parent, A.T.2
Wolosker, H.3
Brady, R.O.4
Linden, D.J.5
Ferris, C.D.6
Rogawski, M.A.7
Snyder, S.H.8
-
4
-
-
2942718893
-
The N-methyl d-aspartate receptor glycine site and d-serine metabolism: an evolutionary perspective
-
Schell M.J. The N-methyl d-aspartate receptor glycine site and d-serine metabolism: an evolutionary perspective. Philos. Trans. R. Soc. Lond. B Biol. Sci. 2004, 359:943-964.
-
(2004)
Philos. Trans. R. Soc. Lond. B Biol. Sci.
, vol.359
, pp. 943-964
-
-
Schell, M.J.1
-
5
-
-
33746362592
-
D-Serine signalling in the brain: friend and foe
-
Martineau M., Baux G., Mothet J.P. d-Serine signalling in the brain: friend and foe. Trends Neurosci. 2006, 29:481-491.
-
(2006)
Trends Neurosci.
, vol.29
, pp. 481-491
-
-
Martineau, M.1
Baux, G.2
Mothet, J.P.3
-
6
-
-
77954584505
-
Metabolism of the neuromodulator d-serine
-
Pollegioni L., Sacchi S. Metabolism of the neuromodulator d-serine. Cell. Mol. Life Sci. 2010, 67:2387-2404.
-
(2010)
Cell. Mol. Life Sci.
, vol.67
, pp. 2387-2404
-
-
Pollegioni, L.1
Sacchi, S.2
-
7
-
-
84857199050
-
Glial d-serine gates NMDA receptors at excitatory synapses in prefrontal cortex
-
Fossat P., Turpin F.R., Sacchi S., Dulong J., Shi T., Rivet J.M., Sweedler J.V., Pollegioni L., Millan M.J., Oliet S.H., Mothet J.P. Glial d-serine gates NMDA receptors at excitatory synapses in prefrontal cortex. Cereb. Cortex 2012, 22:595-606.
-
(2012)
Cereb. Cortex
, vol.22
, pp. 595-606
-
-
Fossat, P.1
Turpin, F.R.2
Sacchi, S.3
Dulong, J.4
Shi, T.5
Rivet, J.M.6
Sweedler, J.V.7
Pollegioni, L.8
Millan, M.J.9
Oliet, S.H.10
Mothet, J.P.11
-
8
-
-
50549088687
-
D-Amino acids in the brain: the biochemistry of brain serine racemase
-
Baumgart F., Rodríguez-Crespo I. d-Amino acids in the brain: the biochemistry of brain serine racemase. FEBS J. 2008, 275:3538-3545.
-
(2008)
FEBS J.
, vol.275
, pp. 3538-3545
-
-
Baumgart, F.1
Rodríguez-Crespo, I.2
-
9
-
-
80054707774
-
Serine racemase and the serine shuttle between neurons and astrocytes
-
Wolosker H. Serine racemase and the serine shuttle between neurons and astrocytes. Biochim. Biophys. Acta 2011, 1814:1558-1566.
-
(2011)
Biochim. Biophys. Acta
, vol.1814
, pp. 1558-1566
-
-
Wolosker, H.1
-
10
-
-
33646522699
-
Glia derived d-serine controls NMDA receptor activity and synaptic memory
-
Panatier A., Theodosis D.T., Mothet J.P., Touquet B., Pollegioni L., Poulain D.A., Oliet S.H. Glia derived d-serine controls NMDA receptor activity and synaptic memory. Cell 2006, 125:775-784.
-
(2006)
Cell
, vol.125
, pp. 775-784
-
-
Panatier, A.1
Theodosis, D.T.2
Mothet, J.P.3
Touquet, B.4
Pollegioni, L.5
Poulain, D.A.6
Oliet, S.H.7
-
11
-
-
33744900653
-
Neuron-derived d-serine release provides a novel means to activate N-methyl-d-aspartate receptors
-
Kartvelishvily E., Shleper M., Balan L., Dumin E., Wolosker H. Neuron-derived d-serine release provides a novel means to activate N-methyl-d-aspartate receptors. J. Biol. Chem. 2006, 281:14151-14162.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 14151-14162
-
-
Kartvelishvily, E.1
Shleper, M.2
Balan, L.3
Dumin, E.4
Wolosker, H.5
-
12
-
-
34447580942
-
Endogenous d-serine contributes to NMDA-receptor-mediated light-evoked responses in the vertebrate retina
-
Gustafson E.C., Stevens E.R., Wolosker H., Miller R.F. Endogenous d-serine contributes to NMDA-receptor-mediated light-evoked responses in the vertebrate retina. J. Neurophysiol. 2007, 98:122-130.
-
(2007)
J. Neurophysiol.
, vol.98
, pp. 122-130
-
-
Gustafson, E.C.1
Stevens, E.R.2
Wolosker, H.3
Miller, R.F.4
-
13
-
-
58149459159
-
Regulation of N-methyl-d-aspartate receptors by astrocytic d-serine
-
Oliet S.H., Mothet J.P. Regulation of N-methyl-d-aspartate receptors by astrocytic d-serine. Neuroscience 2009, 158:275-283.
-
(2009)
Neuroscience
, vol.158
, pp. 275-283
-
-
Oliet, S.H.1
Mothet, J.P.2
-
14
-
-
0037977113
-
Decreased serum levels of d-serine in patients with schizophrenia: evidence in support of the N-methyl-d-aspartate receptor hypofunction hypothesis of schizophrenia
-
Hashimoto K., Fukushima T., Shimizu E., Komatsu N., Watanabe H., Shinoda N., Nakazato M., Kumakiri C., Okada S., Hasegawa H., Imai K., Iyo M. Decreased serum levels of d-serine in patients with schizophrenia: evidence in support of the N-methyl-d-aspartate receptor hypofunction hypothesis of schizophrenia. Arch. Gen. Psychiatry 2003, 60:572-576.
-
(2003)
Arch. Gen. Psychiatry
, vol.60
, pp. 572-576
-
-
Hashimoto, K.1
Fukushima, T.2
Shimizu, E.3
Komatsu, N.4
Watanabe, H.5
Shinoda, N.6
Nakazato, M.7
Kumakiri, C.8
Okada, S.9
Hasegawa, H.10
Imai, K.11
Iyo, M.12
-
15
-
-
33846640657
-
A CSF and postmortem brain study of d-serine metabolic parameters in schizophrenia
-
Bendikov I., Nadri C., Amar S., Panizzutti R., De Miranda J., Wolosker H., Agam G. A CSF and postmortem brain study of d-serine metabolic parameters in schizophrenia. Schizophr. Res. 2007, 90:41-51.
-
(2007)
Schizophr. Res.
, vol.90
, pp. 41-51
-
-
Bendikov, I.1
Nadri, C.2
Amar, S.3
Panizzutti, R.4
De Miranda, J.5
Wolosker, H.6
Agam, G.7
-
16
-
-
27844455892
-
Glutamatergic neurotransmission modulators as emerging new drugs for schizophrenia
-
Heresco-Levy U. Glutamatergic neurotransmission modulators as emerging new drugs for schizophrenia. Expert Opin. Emerg. Drugs 2005, 10:827-844.
-
(2005)
Expert Opin. Emerg. Drugs
, vol.10
, pp. 827-844
-
-
Heresco-Levy, U.1
-
17
-
-
78149428430
-
Rethinking schizophrenia
-
Insel T.R. Rethinking schizophrenia. Nature 2010, 468:187-193.
-
(2010)
Nature
, vol.468
, pp. 187-193
-
-
Insel, T.R.1
-
18
-
-
0037108758
-
Genetic and physiological data implicating the new human gene G72 and the gene for d-amino acid oxidase in schizophrenia
-
Chumakov I., Blumenfeld M., Guerassimenko O., Cavarec L., Palicio M., Abderrahim H., Bougueleret L., Barry C., Tanaka H., La Rosa P., Puech A., Tahri N., Cohen-Akenine A., Delabrosse S., Lissarrague S., Picard F.P., Maurice K., Essioux L., Millasseau P., Grel P., Debailleul V., Simon A.M., Caterina D., Dufaure I., Malekzadeh K., Belova M., Luan J.J., Bouillot M., Sambucy J.L., Primas G., Saumier M., Boubkiri N., Martin-Saumier S., Nasroune M., Peixoto H., Delaye A., Pinchot V., Bastucci M., Guillou S., Chevillon M., Sainz-Fuertes R., Meguenni S., Aurich-Costa J., Cherif D., Gimalac A., Van Duijn C., Gauvreau D., Ouellette G., Fortier I., Raelson J., Sherbatich T., Riazanskaia N., Rogaev E., Raeymaekers P., Aerssens J., Konings F., Luyten W., Macciardi F., Sham P.C., Straub R.E., Weinberger D.R., Cohen N., Cohen D. Genetic and physiological data implicating the new human gene G72 and the gene for d-amino acid oxidase in schizophrenia. Proc. Natl. Acad. Sci. U. S. A. 2002, 99:13675-13680.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 13675-13680
-
-
Chumakov, I.1
Blumenfeld, M.2
Guerassimenko, O.3
Cavarec, L.4
Palicio, M.5
Abderrahim, H.6
Bougueleret, L.7
Barry, C.8
Tanaka, H.9
La Rosa, P.10
Puech, A.11
Tahri, N.12
Cohen-Akenine, A.13
Delabrosse, S.14
Lissarrague, S.15
Picard, F.P.16
Maurice, K.17
Essioux, L.18
Millasseau, P.19
Grel, P.20
Debailleul, V.21
Simon, A.M.22
Caterina, D.23
Dufaure, I.24
Malekzadeh, K.25
Belova, M.26
Luan, J.J.27
Bouillot, M.28
Sambucy, J.L.29
Primas, G.30
Saumier, M.31
Boubkiri, N.32
Martin-Saumier, S.33
Nasroune, M.34
Peixoto, H.35
Delaye, A.36
Pinchot, V.37
Bastucci, M.38
Guillou, S.39
Chevillon, M.40
Sainz-Fuertes, R.41
Meguenni, S.42
Aurich-Costa, J.43
Cherif, D.44
Gimalac, A.45
Van Duijn, C.46
Gauvreau, D.47
Ouellette, G.48
Fortier, I.49
Raelson, J.50
Sherbatich, T.51
Riazanskaia, N.52
Rogaev, E.53
Raeymaekers, P.54
Aerssens, J.55
Konings, F.56
Luyten, W.57
Macciardi, F.58
Sham, P.C.59
Straub, R.E.60
Weinberger, D.R.61
Cohen, N.62
Cohen, D.63
more..
-
19
-
-
52049087606
-
PLG72 modulates intracellular d-serine levels through its interaction with d-amino acid oxidase: effect on schizophrenia susceptibility
-
Sacchi S., Bernasconi M., Martineau M., Mothet J.P., Ruzzene M., Pilone M.S., Pollegioni L., Molla G. pLG72 modulates intracellular d-serine levels through its interaction with d-amino acid oxidase: effect on schizophrenia susceptibility. J. Biol. Chem. 2008, 283:22244-22256.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 22244-22256
-
-
Sacchi, S.1
Bernasconi, M.2
Martineau, M.3
Mothet, J.P.4
Ruzzene, M.5
Pilone, M.S.6
Pollegioni, L.7
Molla, G.8
-
20
-
-
77955102371
-
Effect of ligand binding on human d-amino acid oxidase: implications for the development of new drugs for schizophrenia treatment
-
Caldinelli L., Molla G., Bracci L., Lelli B., Pileri S., Cappelletti P., Sacchi S., Pollegioni L. Effect of ligand binding on human d-amino acid oxidase: implications for the development of new drugs for schizophrenia treatment. Protein Sci. 2010, 19:1500-1512.
-
(2010)
Protein Sci.
, vol.19
, pp. 1500-1512
-
-
Caldinelli, L.1
Molla, G.2
Bracci, L.3
Lelli, B.4
Pileri, S.5
Cappelletti, P.6
Sacchi, S.7
Pollegioni, L.8
-
21
-
-
79960917257
-
Evidence for the interaction of d-amino acid oxidase with pLG72 in a glial cell line
-
Sacchi S., Cappelletti P., Giovannardi S., Pollegioni L. Evidence for the interaction of d-amino acid oxidase with pLG72 in a glial cell line. Mol. Cell. Neurosci. 2011, 48:20-28.
-
(2011)
Mol. Cell. Neurosci.
, vol.48
, pp. 20-28
-
-
Sacchi, S.1
Cappelletti, P.2
Giovannardi, S.3
Pollegioni, L.4
-
22
-
-
75749095178
-
Genetic loss of d-amino acid oxidase activity reverses schizophrenia-like phenotypes in mice
-
Labrie V., Wang W., Barger S.W., Baker G.B., Roder J.C. Genetic loss of d-amino acid oxidase activity reverses schizophrenia-like phenotypes in mice. Genes Brain Behav. 2010, 9:11-25.
-
(2010)
Genes Brain Behav.
, vol.9
, pp. 11-25
-
-
Labrie, V.1
Wang, W.2
Barger, S.W.3
Baker, G.B.4
Roder, J.C.5
-
23
-
-
0034637448
-
Role of arginine 285 in the active site of Rhodotorula gracilis d-amino acid oxidase. A site-directed mutagenesis study
-
Molla G., Porrini D., Job V., Motteran L., Vegezzi C., Campaner S., Pilone M.S., Pollegioni L. Role of arginine 285 in the active site of Rhodotorula gracilis d-amino acid oxidase. A site-directed mutagenesis study. J. Biol. Chem. 2000, 275:24715-24721.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 24715-24721
-
-
Molla, G.1
Porrini, D.2
Job, V.3
Motteran, L.4
Vegezzi, C.5
Campaner, S.6
Pilone, M.S.7
Pollegioni, L.8
-
24
-
-
33751519528
-
Crystal structure of human d-amino acid oxidase: context-dependent variability of the backbone conformation of the VAAGL hydrophobic stretch located at the si-face of the flavin ring
-
Kawazoe T., Tsuge H., Pilone M.S., Fukui K. Crystal structure of human d-amino acid oxidase: context-dependent variability of the backbone conformation of the VAAGL hydrophobic stretch located at the si-face of the flavin ring. Protein Sci. 2006, 15:2708-2717.
-
(2006)
Protein Sci.
, vol.15
, pp. 2708-2717
-
-
Kawazoe, T.1
Tsuge, H.2
Pilone, M.S.3
Fukui, K.4
-
25
-
-
0023681465
-
Molecular cloning and sequence analysis of cDNA encoding human kidney d-amino acid oxidase
-
Momoi K., Fukui K., Watanabe F., Miyake Y. Molecular cloning and sequence analysis of cDNA encoding human kidney d-amino acid oxidase. FEBS Lett. 1988, 238:180-184.
-
(1988)
FEBS Lett.
, vol.238
, pp. 180-184
-
-
Momoi, K.1
Fukui, K.2
Watanabe, F.3
Miyake, Y.4
-
26
-
-
3142653173
-
Unfolding intermediate in the peroxisomal flavoprotein d-amino acid oxidase
-
Caldinelli L., Iametti S., Barbiroli A., Bonomi F., Piubelli L., Ferranti P., Picariello G., Pilone M.S., Pollegioni L. Unfolding intermediate in the peroxisomal flavoprotein d-amino acid oxidase. J. Biol. Chem. 2004, 279:28426-28434.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 28426-28434
-
-
Caldinelli, L.1
Iametti, S.2
Barbiroli, A.3
Bonomi, F.4
Piubelli, L.5
Ferranti, P.6
Picariello, G.7
Pilone, M.S.8
Pollegioni, L.9
-
27
-
-
33646002696
-
Characterization of human d-amino acid oxidase
-
Molla G., Sacchi S., Bernasconi M., Pilone M.S., Fukui K., Pollegioni L. Characterization of human d-amino acid oxidase. FEBS Lett. 2006, 580:2358-2364.
-
(2006)
FEBS Lett.
, vol.580
, pp. 2358-2364
-
-
Molla, G.1
Sacchi, S.2
Bernasconi, M.3
Pilone, M.S.4
Fukui, K.5
Pollegioni, L.6
-
28
-
-
32644480821
-
Expression in Escherichia coli and in vitro refolding of the human protein pLG72
-
Molla G., Bernasconi M., Sacchi S., Pilone M.S., Pollegioni L. Expression in Escherichia coli and in vitro refolding of the human protein pLG72. Protein Expr. Purif. 2006, 46:150-155.
-
(2006)
Protein Expr. Purif.
, vol.46
, pp. 150-155
-
-
Molla, G.1
Bernasconi, M.2
Sacchi, S.3
Pilone, M.S.4
Pollegioni, L.5
-
29
-
-
0015608091
-
Equilibrium binding of nicotinamide nucleotides to lactate dehydrogenases
-
Stinson R.A., Holbrook J.J. Equilibrium binding of nicotinamide nucleotides to lactate dehydrogenases. Biochem. J. 1973, 131:719-728.
-
(1973)
Biochem. J.
, vol.131
, pp. 719-728
-
-
Stinson, R.A.1
Holbrook, J.J.2
-
30
-
-
63449109647
-
Relevance of weak flavin binding in human d-amino acid oxidase
-
Caldinelli L., Molla G., Sacchi S., Pilone M.S., Pollegioni L. Relevance of weak flavin binding in human d-amino acid oxidase. Protein Sci. 2009, 18:801-810.
-
(2009)
Protein Sci.
, vol.18
, pp. 801-810
-
-
Caldinelli, L.1
Molla, G.2
Sacchi, S.3
Pilone, M.S.4
Pollegioni, L.5
-
31
-
-
50049104451
-
Optimization of glutaryl-7-aminocephalosporanic acid acylase expression in E. coli
-
Volontè F., Marinelli F., Gastaldo L., Sacchi S., Pilone M.S., Pollegioni L., Molla G. Optimization of glutaryl-7-aminocephalosporanic acid acylase expression in E. coli. Protein Expr. Purif. 2008, 61:131-137.
-
(2008)
Protein Expr. Purif.
, vol.61
, pp. 131-137
-
-
Volontè, F.1
Marinelli, F.2
Gastaldo, L.3
Sacchi, S.4
Pilone, M.S.5
Pollegioni, L.6
Molla, G.7
-
32
-
-
0030925616
-
Active site plasticity in d-amino acid oxidase: a crystallographic analysis
-
Todone F., Vanoni M.A., Mozzarelli A., Bolognesi M., Coda A., Curti B., Mattevi A. Active site plasticity in d-amino acid oxidase: a crystallographic analysis. Biochemistry 1997, 36:5853-5860.
-
(1997)
Biochemistry
, vol.36
, pp. 5853-5860
-
-
Todone, F.1
Vanoni, M.A.2
Mozzarelli, A.3
Bolognesi, M.4
Coda, A.5
Curti, B.6
Mattevi, A.7
-
33
-
-
0029839452
-
Crystal structure of d-amino acid oxidase: a case of active site mirror-image convergent evolution with flavocytochrome b2
-
Mattevi A., Vanoni M.A., Todone F., Rizzi M., Teplyakov A., Coda A., Bolognesi M., Curti B. Crystal structure of d-amino acid oxidase: a case of active site mirror-image convergent evolution with flavocytochrome b2. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:7496-7501.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 7496-7501
-
-
Mattevi, A.1
Vanoni, M.A.2
Todone, F.3
Rizzi, M.4
Teplyakov, A.5
Coda, A.6
Bolognesi, M.7
Curti, B.8
-
34
-
-
77952194773
-
Familial amyotrophic lateral sclerosis is associated with a mutation in d-amino acid oxidase
-
Mitchell J., Paul P., Chen H.J., Morris A., Payling M., Falchi M., Habgood J., Panoutsou S., Winkler S., Tisato V., Hajitou A., Smith B., Vance C., Shaw C., Mazarakis N.D., de Belleroche J. Familial amyotrophic lateral sclerosis is associated with a mutation in d-amino acid oxidase. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:7556-7561.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 7556-7561
-
-
Mitchell, J.1
Paul, P.2
Chen, H.J.3
Morris, A.4
Payling, M.5
Falchi, M.6
Habgood, J.7
Panoutsou, S.8
Winkler, S.9
Tisato, V.10
Hajitou, A.11
Smith, B.12
Vance, C.13
Shaw, C.14
Mazarakis, N.D.15
de Belleroche, J.16
-
35
-
-
84877723597
-
D-Amino acid oxidase as a novel class of drug for schizophrenia therapy
-
(Ahead of print)
-
Sacchi S., Rosini E., Pollegioni L., Molla G. d-Amino acid oxidase as a novel class of drug for schizophrenia therapy. Curr. Pharm. Des. 2013, 19. (Ahead of print).
-
(2013)
Curr. Pharm. Des.
, vol.19
-
-
Sacchi, S.1
Rosini, E.2
Pollegioni, L.3
Molla, G.4
-
36
-
-
84856089057
-
Contributions of the d-serine pathway to schizophrenia
-
Labrie V., Wong A.H., Roder J.C. Contributions of the d-serine pathway to schizophrenia. Neuropharmacology 2012, 62:1484-1503.
-
(2012)
Neuropharmacology
, vol.62
, pp. 1484-1503
-
-
Labrie, V.1
Wong, A.H.2
Roder, J.C.3
|