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Volumn 125, Issue 21, 2012, Pages 4979-4984

Karyopherin-independent spontaneous transport of amphiphilic proteins through the nuclear pore

Author keywords

Amphiphilic motif; Karyopherin; Nuclear pore complex; Nuclear transport; Surface hydrophobicity

Indexed keywords

AMPHIPHILIC PROTEIN; AMPHOPHILE; KARYOPHERIN; NUCLEOCYTOPLASMIC TRANSPORT PROTEIN; UNCLASSIFIED DRUG;

EID: 84872221907     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.109520     Document Type: Article
Times cited : (26)

References (29)
  • 1
    • 0025083331 scopus 로고
    • Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors
    • Adam, S. A., Marr, R. S. and Gerace, L. (1990). Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors. J. Cell Biol. 111, 807-816.
    • (1990) J. Cell Biol , vol.111 , pp. 807-816
    • Adam, S.A.1    Marr, R.S.2    Gerace, L.3
  • 2
    • 0034616910 scopus 로고    scopus 로고
    • Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking
    • Bayliss, R., Littlewood, T. and Stewart, M. (2000). Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking. Cell 102, 99-108.
    • (2000) Cell , vol.102 , pp. 99-108
    • Bayliss, R.1    Littlewood, T.2    Stewart, M.3
  • 3
    • 0037184968 scopus 로고    scopus 로고
    • GLFG and FxFG nucleoporins bind to overlapping sites on importin-beta
    • Bayliss, R., Littlewood, T., Strawn, L. A., Wente, S. R. and Stewart, M. (2002). GLFG and FxFG nucleoporins bind to overlapping sites on importin-beta. J. Biol. Chem. 277, 50597-50606.
    • (2002) J. Biol. Chem , vol.277 , pp. 50597-50606
    • Bayliss, R.1    Littlewood, T.2    Strawn, L.A.3    Wente, S.R.4    Stewart, M.5
  • 4
    • 0041731883 scopus 로고    scopus 로고
    • Importin beta contains a COOHterminal nucleoporin binding region important for nuclear transport
    • Bednenko, J., Cingolani, G. and Gerace, L. (2003). Importin beta contains a COOHterminal nucleoporin binding region important for nuclear transport. J. Cell Biol. 162, 391-401.
    • (2003) J. Cell Biol , vol.162 , pp. 391-401
    • Bednenko, J.1    Cingolani, G.2    Gerace, L.3
  • 6
    • 0037418190 scopus 로고    scopus 로고
    • Disorder in the nuclear pore complex: the FG repeat regions of nucleoporins are natively unfolded
    • Denning, D. P., Patel, S. S., Uversky, V., Fink, A. L. and Rexach, M. (2003). Disorder in the nuclear pore complex: the FG repeat regions of nucleoporins are natively unfolded. Proc. Natl. Acad. Sci. USA 100, 2450-2455.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 2450-2455
    • Denning, D.P.1    Patel, S.S.2    Uversky, V.3    Fink, A.L.4    Rexach, M.5
  • 7
    • 23944501630 scopus 로고    scopus 로고
    • Self-organization in protein folding and the hydrophobic interaction
    • Gerstman, B. S. and Chapagain, P. P. (2005). Self-organization in protein folding and the hydrophobic interaction. J. Chem. Phys. 123, 054901.
    • (2005) J. Chem. Phys , vol.123 , pp. 054901
    • Gerstman, B.S.1    Chapagain, P.P.2
  • 8
    • 34548847733 scopus 로고    scopus 로고
    • Using circular dichroism spectra to estimate protein secondary structure
    • Greenfield, N. J. (2007). Using circular dichroism spectra to estimate protein secondary structure. Nat. Protoc. 1, 2876-2890.
    • (2007) Nat. Protoc , vol.1 , pp. 2876-2890
    • Greenfield, N.J.1
  • 9
    • 0002636134 scopus 로고
    • Pairwise solute descreening of solute charges from a dielectric medium
    • Hawkins, G. D., Cramer, C. J. and Truhlar, D. G. (1995). Pairwise solute descreening of solute charges from a dielectric medium. Chem. Phys. Lett. 246, 122-129.
    • (1995) Chem. Phys. Lett. , vol.246 , pp. 122-129
    • Hawkins, G.D.1    Cramer, C.J.2    Truhlar, D.G.3
  • 10
    • 33748390341 scopus 로고    scopus 로고
    • Parametrized models of aqueous free energies of solvation based on pairwise descreening of solute atomic charges from a dielectric medium
    • Hawkins, G. D., Cramer, C. J. and Truhlar, D. G. (1996). Parametrized models of aqueous free energies of solvation based on pairwise descreening of solute atomic charges from a dielectric medium. J. Phys. Chem. 100, 19824-19839.
    • (1996) J. Phys. Chem. , vol.100 , pp. 19824-19839
    • Hawkins, G.D.1    Cramer, C.J.2    Truhlar, D.G.3
  • 11
    • 77951159377 scopus 로고    scopus 로고
    • Molecular mechanisms underlying nucleocytoplasmic shuttling of actinin-4
    • Kumeta, M., Yoshimura, S. H., Harata, M. and Takeyasu, K. (2010). Molecular mechanisms underlying nucleocytoplasmic shuttling of actinin-4. J. Cell Sci. 123, 1020-1030.
    • (2010) J. Cell Sci. , vol.123 , pp. 1020-1030
    • Kumeta, M.1    Yoshimura, S.H.2    Harata, M.3    Takeyasu, K.4
  • 12
    • 84855606946 scopus 로고    scopus 로고
    • Nucleocytoplasmic shuttling of cytoskeletal proteins: molecular mechanism and biological significance
    • Kumeta, M., Yoshimura, S. H., Hejna, J. and Takeyasu, K. (2012). Nucleocytoplasmic shuttling of cytoskeletal proteins: molecular mechanism and biological significance. Int. J. Cell Biol. 2012, 494902.
    • (2012) Int. J. Cell Biol. , vol.2012 , pp. 494902
    • Kumeta, M.1    Yoshimura, S.H.2    Hejna, J.3    Takeyasu, K.4
  • 13
    • 0030960586 scopus 로고    scopus 로고
    • Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex
    • Kutay, U., Izaurralde, E., Bischoff, F. R., Mattaj, I. W. and Görlich, D. (1997). Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex. EMBO J. 16, 1153-1163.
    • (1997) EMBO J. , vol.16 , pp. 1153-1163
    • Kutay, U.1    Izaurralde, E.2    Bischoff, F.R.3    Mattaj, I.W.4    Görlich, D.5
  • 14
    • 34247135913 scopus 로고    scopus 로고
    • Classical nuclear localization signals: definition, function, and interaction with importin alpha
    • Lange, A., Mills, R. E., Lange, C. J., Stewart, M., Devine, S. E. and Corbett, A. H. (2007). Classical nuclear localization signals: definition, function, and interaction with importin alpha. J. Biol. Chem. 282, 5101-5105.
    • (2007) J. Biol. Chem , vol.282 , pp. 5101-5105
    • Lange, A.1    Mills, R.E.2    Lange, C.J.3    Stewart, M.4    Devine, S.E.5    Corbett, A.H.6
  • 15
    • 84855690465 scopus 로고    scopus 로고
    • Prediction of protein secondary structure from circular dichroism using theoretically derived spectra
    • Louis-Jeune, C., Andrade-Navarro, M. A. and Perez-Iratxeta, C. (2011). Prediction of protein secondary structure from circular dichroism using theoretically derived spectra. Proteins 80, 374-381.
    • (2011) Proteins , vol.80 , pp. 74-381
    • Louis-Jeune, C.1    Andrade-Navarro, M.A.2    Perez-Iratxeta, C.3
  • 16
    • 0031470630 scopus 로고    scopus 로고
    • Evolutionary specialization of the nuclear targeting apparatus
    • Malik, H. S., Eickbush, T. H. and Goldfarb, D. S. (1997). Evolutionary specialization of the nuclear targeting apparatus. Proc. Natl. Acad. Sci. USA 94, 13738-13742
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 13738-13742
    • Malik, H.S.1    Eickbush, T.H.2    Goldfarb, D.S.3
  • 17
    • 69849093363 scopus 로고    scopus 로고
    • Characterisation of the passive permeability barrier of nuclear pore complexes
    • Mohr, D., Frey, S., Fischer, T., Güttler, T. and Görlich, D. (2009). Characterisation of the passive permeability barrier of nuclear pore complexes. EMBO J. 28, 2541-2553.
    • (2009) EMBO J. , vol.28 , pp. 2541-2553
    • Mohr, D.1    Frey, S.2    Fischer, T.3    Güttler, T.4    Görlich, D.5
  • 18
    • 4644278442 scopus 로고    scopus 로고
    • Karyopherins: from nucleartransport mediators to nuclear-function regulators
    • Mosammaparast, N. and Pemberton, L. F. (2004). Karyopherins: from nucleartransport mediators to nuclear-function regulators. Trends Cell Biol. 14, 547-556.
    • (2004) Trends Cell Biol. , vol.14 , pp. 547-556
    • Mosammaparast, N.1    Pemberton, L.F.2
  • 19
    • 0033578298 scopus 로고    scopus 로고
    • The direction of transport through the nuclear pore can be inverted
    • USA
    • Nachury, M. V. and Weis, K. (1999). The direction of transport through the nuclear pore can be inverted. Proc. Natl. Acad. Sci. USA 96, 9622-9627.
    • (1999) Proc. Natl. Acad. Sci. , vol.96 , pp. 9622-9627
    • Nachury, M.V.1    Weis, K.2
  • 20
    • 70349208472 scopus 로고    scopus 로고
    • Cargo surface hydrophobicity is sufficient to overcome the nuclear pore complex selectivity barrier
    • Naim, B., Zbaida, D., Dagan, S., Kapon, R. and Reich, Z. (2009). Cargo surface hydrophobicity is sufficient to overcome the nuclear pore complex selectivity barrier. EMBO J. 28, 2697-2705.
    • (2009) EMBO J. , vol.28 , pp. 2697-2705
    • Naim, B.1    Zbaida, D.2    Dagan, S.3    Kapon, R.4    Reich, Z.5
  • 21
    • 0030967789 scopus 로고    scopus 로고
    • Nuclear-cytoplasmic shuttling of the focal contact protein, zyxin: a potential mechanism for communication between sites of cell adhesion and the nucleus
    • Nix, D. A. and Beckerle, M. C. (1997). Nuclear-cytoplasmic shuttling of the focal contact protein, zyxin: a potential mechanism for communication between sites of cell adhesion and the nucleus. J. Cell Biol. 138, 1139-1147.
    • (1997) J. Cell Biol. , vol.138 , pp. 1139-1147
    • Nix, D.A.1    Beckerle, M.C.2
  • 22
    • 55849144420 scopus 로고    scopus 로고
    • Individual binding pockets of importin-beta for FG-nucleoporins have different binding properties and different sensitivities to RanGTP
    • USA
    • Otsuka, S., Iwasaka, S., Yoneda, Y., Takeyasu, K. and Yoshimura, S. H. (2008). Individual binding pockets of importin-beta for FG-nucleoporins have different binding properties and different sensitivities to RanGTP. Proc. Natl. Acad. Sci. USA 105, 16101-16106.
    • (2008) Proc. Natl. Acad. Sci. , vol.105 , pp. 16101-16106
    • Otsuka, S.1    Iwasaka, S.2    Yoneda, Y.3    Takeyasu, K.4    Yoshimura, S.H.5
  • 23
    • 22344441238 scopus 로고    scopus 로고
    • The tumor suppressor Scrib interacts with the zyxin-related protein LPP, which shuttles between cell adhesion sites and the nucleus
    • Petit, M. M., Meulemans, S. M., Alen, P., Ayoubi, T. A., Jansen, E. and Van de Ven, W. J. (2005). The tumor suppressor Scrib interacts with the zyxin-related protein LPP, which shuttles between cell adhesion sites and the nucleus. BMC Cell Biol. 6, 1.
    • (2005) BMC Cell Biol , vol.6 , pp. 1
    • Petit, M.M.1    Meulemans, S.M.2    Alen, P.3    Ayoubi, T.A.4    Jansen, E.5    Van de Ven, W.J.6
  • 24
    • 0037013954 scopus 로고    scopus 로고
    • The permeability barrier of nuclear pore complexes appears to operate via hydrophobic exclusion
    • Ribbeck, K. and Görlich, D. (2002). The permeability barrier of nuclear pore complexes appears to operate via hydrophobic exclusion. EMBO J. 21, 2664-2671.
    • (2002) EMBO J. , vol.21 , pp. 2664-2671
    • Ribbeck, K.1    Görlich, D.2
  • 25
    • 0242641546 scopus 로고    scopus 로고
    • Exportin 6: a novel nuclear export receptor that is specific for profilin.actin complexes
    • Stüven, T., Hartmann, E. and Görlich, D. (2003). Exportin 6: a novel nuclear export receptor that is specific for profilin.actin complexes. EMBO J. 22, 5928-5940.
    • (2003) EMBO J. , vol.22 , pp. 5928-5940
    • Stüven, T.1    Hartmann, E.2    Görlich, D.3
  • 26
    • 14244273182 scopus 로고    scopus 로고
    • Theory and applications of the generalized Born solvation model in macromolecular simulations
    • Tsui, V. and Case, D. A. (2001). Theory and applications of the generalized Born solvation model in macromolecular simulations. Biopolymers 56, 275-291.
    • (2001) Biopolymers , vol.56 , pp. 275-291
    • Tsui, V.1    Case, D.A.2
  • 27
    • 0032536820 scopus 로고    scopus 로고
    • Nuclear export of actin: a novel mechanism regulating the subcellular localization of a major cytoskeletal protein
    • Wada, A., Fukuda, M., Mishima, M. and Nishida, E. (1998). Nuclear export of actin: a novel mechanism regulating the subcellular localization of a major cytoskeletal protein. EMBO J. 17, 1635-1641.
    • (1998) EMBO J. , vol.17 , pp. 1635-1641
    • Wada, A.1    Fukuda, M.2    Mishima, M.3    Nishida, E.4
  • 29
    • 0032910953 scopus 로고    scopus 로고
    • beta-catenin can be transported into the nucleus in a Ran-unassisted manner
    • Yokoya, F., Imamoto, N., Tachibana, T. and Yoneda, Y. (1999). beta-catenin can be transported into the nucleus in a Ran-unassisted manner. Mol. Biol. Cell 10, 1119-1131.
    • (1999) Mol. Biol. Cell , vol.10 , pp. 119-1131
    • Yokoya, F.1    Imamoto, N.2    Tachibana, T.3    Yoneda, Y.4


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