Characterization of the chemical reactivity and nephrotoxicity of N-acetyl-S-(1,2-dichlorovinyl)-l-cysteine sulfoxide, a potential reactive metabolite of trichloroethylene

Toxicology and Applied Pharmacology

Volumn 267, Issue 1, 2013, Pages 1-10

  Irving, Roy M ^a   Pinkerton, Marie E ^a   Elfarra, Adnan A ^a,b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

GSH conjugation; N acetyl S (1,2 dichlorovinyl) l cysteine; N acetyl S (1,2 dichlorovinyl) l cysteine sulfoxide; Nephrotoxicity; S (1,2 dichlorovinyl) l cysteine; Trichloroethylene

Indexed keywords

CYSTEINE DERIVATIVE; GLUTATHIONE; HEMOGLOBIN; N ACETYL S (1,2 DICHLOROVINYL)CYSTEINE SULFOXIDE; PHOSPHATE; S (1,2 DICHLOROVINYL)CYSTEINE SULFOXIDE; TRICHLOROETHYLENE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATALYSIS; CONJUGATION; CONTROLLED STUDY; HALF LIFE TIME; HISTOPATHOLOGY; IN VIVO STUDY; KIDNEY CORTEX; KIDNEY MEDULLA; KIDNEY PROXIMAL TUBULE; LIVER CYTOSOL; LIVER METABOLISM; MALE; NEPHROTOXICITY; NONHUMAN; RAT;

ACETYLCYSTEINE; ANIMALS; KIDNEY DISEASES; MALE; RATS; RATS, SPRAGUE-DAWLEY; TRICHLOROETHYLENE;

RATTUS;

EID: 84872194618     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.12.002     Document Type: Article

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