Focus on molecules: SFRP1

Experimental Eye Research

Volumn 91, Issue 5, 2010, Pages 552-553

  Mao, Weiming ^a   Wordinger, Robert J ^a   Clark, Abbot F ^a  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

Author keywords

Glaucoma; Intraocular pressure; Ocular diseases; SFRP1; Wnt signaling

Indexed keywords

SECRETED FRIZZLED RELATED PROTEIN 1; MEMBRANE PROTEIN; SFRP1 PROTEIN, HUMAN; SIGNAL PEPTIDE; WNT PROTEIN;

ENDOCRINE OPHTHALMOPATHY; HUMAN; KERATOCONUS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; RETINA DEGENERATION; SHORT SURVEY; ARTICLE; CHEMISTRY; EYE DISEASE; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

EYE DISEASES; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 78049496562     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2010.05.003     Document Type: Short Survey

References (4)

1. Bovolenta P., Esteve P., Ruiz J.M., Cisneros E., Lopez-Rios J. Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease. J. Cell Sci. 2008, 121:737-746.
2. de Iongh R.U., Abud H.E., Hime G.R. WNT/Frizzled signaling in eye development and disease. Front. Biosci. 2006, 11:2442-2464.
3. Sutton G., Madigan M., Roufas A., McAvoy J. Secreted frizzled-related protein 1 (SFRP1) is highly upregulated in keratoconus epithelium: a novel finding highlighting a new potential focus for keratoconus research and treatment. Clin. Experiment Ophthalmol. 2010, 38:43-48.
4. Wang W.H., McNatt L.G., Pang I.H., Millar J.C., Hellberg P.E., Hellberg M.H., Steely H.T., Rubin J.S., Fingert J.H., Sheffield V.C., Stone E.M., Clark A.F. Increased expression of the WNT antagonist sFRP-1 in glaucoma elevates intraocular pressure. J. Clin. Invest. 2008, 118:1056-1064.