Bone morphogenetic protein 4 inhibits TGF-β2 stimulation of extracellular matrix proteins in optic nerve head cells: Role of gremlin in ECM modulation

GLIA

Volumn 57, Issue 7, 2009, Pages 755-766

  Zode, Gulab S ^a   Clark, Abbot F ^a   Wordinger, Robert J ^a  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

Author keywords

BMPs; ECM remodeling; Gremlin; LC cells; ONH astrocytes; TGF 2

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; COLLAGEN TYPE 1; COLLAGEN TYPE 6; ELASTIN; FIBRONECTIN; GREMLIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN; RECEPTOR REGULATED SMAD PROTEIN; RECOMBINANT OSTEOGENIC PROTEIN 1; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA2; SCLEROPROTEIN; SMAD3 PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; ASTROCYTE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; GENE CONTROL; GLAUCOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; LAMINA CRIBROSA CELL; NERVE CELL; NEUROMODULATION; OPTIC NERVE; OPTIC NERVE HEAD CELL; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

AGED; AGED, 80 AND OVER; ASTROCYTES; BONE MORPHOGENETIC PROTEIN 4; CELL LINE; CELL LINE, TUMOR; COLLAGEN; ELASTIN; EXTRACELLULAR MATRIX PROTEINS; FIBRONECTINS; GENE EXPRESSION; GLAUCOMA; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; OPTIC DISK; PHOSPHORYLATION; PLASMINOGEN ACTIVATOR INHIBITOR 1; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RNA, MESSENGER; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA2;

EID: 66249114647     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.20803     Document Type: Article

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