REV3L 3′UTR 460 T>C polymorphism in microRNA target sites contributes to lung cancer susceptibility

Oncogene

Volumn 32, Issue 2, 2013, Pages 242-250

  Zhang, S ^a,b   Chen, H ^a   Zhao, X ^a   Cao, J ^b   Tong, J ^b   Lu, J ^a   Wu, W ^a   Shen, H ^c   Wei, Q ^d   Lu, D ^a  

^a FUDAN UNIVERSITY   (China)

^b MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

^c NANJING MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

genetic polymorphism; lung cancer; microRNA; REV3L

Indexed keywords

DNA POLYMERASE REV1; MICRORNA; MICRORNA 25; MICRORNA 32; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; DNA DIRECTED DNA POLYMERASE; MIRN25 MICRORNA, HUMAN; MIRN32 MICRORNA, HUMAN; REV3L PROTEIN, HUMAN;

3' UNTRANSLATED REGION; ALLELE; ARTICLE; BINDING AFFINITY; CANCER RISK; CANCER SUSCEPTIBILITY; CHINESE; CONTROLLED STUDY; DNA REPLICATION; DOWN REGULATION; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG CANCER; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; CHINA; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; GENOMIC INSTABILITY; GENOTYPE; LUNG TUMOR; METABOLISM; RISK; RISK FACTOR; TUMOR CELL LINE;

3' UNTRANSLATED REGIONS; CELL LINE, TUMOR; CHINA; DNA-BINDING PROTEINS; DNA-DIRECTED DNA POLYMERASE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC PREDISPOSITION TO DISEASE; GENOMIC INSTABILITY; GENOTYPE; HUMANS; LUNG NEOPLASMS; MICRORNAS; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK; RISK FACTORS;

MLCS; MLOWN;

EID: 84872190164     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.32     Document Type: Article

References (39)

1. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin 2011; 61: 69-90.
2. Hoeijmakers JH. Genome maintenance mechanisms are critical for preventing cancer as well as other aging-Associated diseases. Mech Ageing Dev 2007; 128: 460-462. (Pubitemid 47223370)
3. Sonoda E, Okada T, Zhao GY, Tateishi S, Araki K, Yamaizumi M et al. Multiple roles of Rev3, the catalytic subunit of polzeta in maintaining genome stability in vertebrates. Embo J 2003; 22: 3188-3197. (Pubitemid 36758638)
4. Friedberg EC, Lehmann AR, Fuchs RP. Trading places: how do DNA polymerases switch during translesion DNA synthesisMol Cell 2005; 18: 499-505. (Pubitemid 40726227)
5. Venkatesan RN, Bielas JH, Loeb LA. Generation of mutator mutants during carcinogenesis. DNA Repai (Amst) 2006; 5: 294-302. (Pubitemid 43247596)
6. Matsuda T, Bebenek K, Masutani C, Hanaoka F, Kunkel TA. Low fidelity DNA synthesis by human DNA polymerase-eta. Nature 2000; 404: 1011-1013. (Pubitemid 30243597)
7. Johnson RE, Washington MT, Haracska L, Prakash S, Prakash L. Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesions. Nature 2000; 406: 1015-1019.
8. Zhang Y, Yuan F, Wu X, Wang Z. Preferential incorporation of G opposite template T by the low-fidelity human DNA polymerase iota. Mol Cell Biol 2000; 20: 7099-7108.
9. Gan GN, Wittschieben JP, Wittschieben BØ, Wood RD. DNA polymerase zeta (pol zeta) in higher eukaryotes. Cell Res 2008; 18: 174-183.
10. Lawrence CW, Maher VM. Mutagenesis in eukaryotes dependent on DNA polymerase zeta and Rev1p. Philos Trans R Soc Lond B Biol Sci 2001; 356: 41-46. (Pubitemid 32575586)
11. Lemontt JF. Induction of forward mutations in mutationally defective yeast. Mol Gen Genet 1972; 119: 27-42.
12. Wittschieben JP, Reshmi SC, Gollin SM, Wood RD. Loss of DNA polymerase zeta causes chromosomal instability in mammalian cells. Cancer Res 2006; 66: 134-142. (Pubitemid 43166018)
13. Nojima K, Hochegger H, Saberi A, Fukushima T, Kikuchi K, Yoshimura M et al. Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells. Cancer Res 2005; 65: 11704-11711. (Pubitemid 41821731)
14. Bemark M, Khamlichi AA, Davies SL, Neuberger MS. Disruption of mouse polymerase zeta (Rev3) leads to embryonic lethality and impairs blastocyst development in vitro. Curr Biol 2000; 10: 1213-1216.
15. Esposito G, Godindagger I, Klein U, Yaspo ML, Cumano A, Rajewsky K. Disruption of the Rev3l-encoded catalytic subunit of polymerase zeta in mice results in early embryonic lethality. Curr Biol 2000; 10: 1221-1224.
16. Zhu F, Jin CX, Song T, Yang J, Guo L, Yu YN. Response of human REV3 gene to gastric cancer inducing carcinogen N-methyl-N0-nitro-N-nitrosoguanidine and its role in mutagenesis. World J Gastroenterol 2003; 9: 888-893. (Pubitemid 36681650)
17. Brondello JM, Pillaire MJ, Rodriguez C, Gourraud PA, Selves J, Cazaux C et al. Novel evidences for a tumor suppressor role of Rev3, the catalytic subunit of Pol zeta. Oncogene 2008; 27: 6093-6101.
18. Pan Q, Fang Y, Xu Y, Zhang K, Hu X. Down-regulation of DNA polymerases kappa, eta, iota, and zeta in human lung, stomach, and colorectal cancers. Cancer Lett 2005; 217: 139-147. (Pubitemid 40023112)
19. Hu Z, Wang H, Shao M, Jin G, Sun W, Wang Y et al. Genetic variants in MGMT and risk of lung cancer in Southeastern Chinese: A haplotype-based analysis. Hum Mutat 2007; 28: 431-440. (Pubitemid 46668601)
20. Lu J, Zhang S, Chen D, Wang H, Wu W, Wang X et al. Functional characterization of a promoter polymorphism in APE1/Ref-1 that contributes to reduced lung cancer susceptibility. FASEB J 2009; 23: 3459-3469.
21. Wang QZ, Xu W, Habib N, Xu R. Potential uses of microRNA in lung cancer diagnosis, prognosis, and therapy. Curr Cancer Drug Targets 2009; 9: 572-594.
22. Wang HB, Zhang SY, Wang S, Lv J, Wu WT, Weng L et al. REV3L confers chemoresistance to cisplatin in human gliomas: The potential of its RNAi for synergistic therapy. Neuro Oncol 2009; 11: 790-802.
23. Lehmann AR. Replication of damaged DNA by translesion synthesis in human cells. FEBS Lett 2005; 579: 873-876. (Pubitemid 40361857)
24. Rockwell S, Yuan J, Peretz S, Glazer PM. Genomic instability in cancer. Novartis Found Symp 2001; 240: 133-142; discussion 142-151. (Pubitemid 33603784)
25. Gibbs PE, McGregor WG, Maher VM, Nisson P, Lawrence CW. A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta. Proc Natl Acad Sci USA 1998; 95: 6876-6880. (Pubitemid 28278074)
26. Lin W, Wu X, Wang Z. A full-length cDNA of hREV3 is predicted to encode DNA polymerase zeta for damage-induced mutagenesis in humans. Mutat Res 1999; 433: 89-98. (Pubitemid 29101630)
27. Datta A, Jinks-Robertson S. Association of increased spontaneous mutation rates with high levels of transcription in yeast. Science 1995; 268: 1616-1619.
28. Kajiwara K, Nagawawa H, Shimizu-Nishikawa S, Ookuri T, Kimura M, Sugaya E. Molecular characterization of seizure-related genes isolated by differential screening. Biochem Biophys Res Commun 1996; 219: 795-799. (Pubitemid 26106761)
29. Krieg AJ, Hammond EM, Giaccia AJ. Functional analysis of p53 binding under differential stresses. Mol Cell Biol 2006; 26: 7030-7045. (Pubitemid 44477683)
30. Kim VN, Nam JW. Genomics of microRNA. Trends Genet 2006; 22: 165-173. (Pubitemid 43290020)
31. Doench JG, Sharp PA. Specificity of microRNA target selection in translational repression. Genes Dev 2004; 18: 504-511. (Pubitemid 38372808)
32. Vatolin S, Navaratne K, Weil RJ. A novel method to detect functional microRNA targets. J Mol Biol 2006; 358: 983-996.
33. Saunders MA, Liang H, Li WH. Human polymorphism at microRNAs and microRNA target sites. Proc Natl Acad Sci USA 2007; 104: 3300-3305. (Pubitemid 46364154)
34. Yu Z, Li Z, Jolicoeur N, Zhang L, Fortin Y, Wang E et al. Aberrant allele frequencies of the SNPs located in microRNA target sites are potentially associated with human cancers. Nucleic Acids Res 2007; 35: 4535-4541. (Pubitemid 47244604)
35. Nicoloso MS, Sun H, Spizzo R, Kim H, Wickramasinghe P, Shimizu M et al. Singlenucleotide polymorphisms inside microRNA target sites influence tumor susceptibility. Cancer Res 2010; 70: 2789-2798.
36. Clop A, Marcq F, Takeda H, Pirottin D, Tordoir X, Bibe B et al. A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep. Nat Genet 2006; 38: 813-818. (Pubitemid 43980603)
37. Mishra PJ, Humeniuk R, Mishra PJ, Longo-Sorbello GS, Banerjee D, Bertino Jr. A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance. Proc Natl Acad Sci USA 2007; 104: 13513-13518. (Pubitemid 47293976)
38. Wang G, van der Walt JM, Mayhew G, Li YJ, Zuchner S, Scott WK et al. Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein. Am J Hum Genet 2008; 82: 283-289.
39. Chen D, Jin G, Wang Y, Wang H, Liu H, Liu Y et al. Genetic variants in peroxisome proliferator-Activated receptor-gamma gene are associated with risk of lung cancer in a Chinese population. Carcinogenesis 2008; 29: 342-350. (Pubitemid 351359673)