Combining heavy ion radiation and artificial microRNAs to target the homologous recombination repair gene efficiently kills human tumor cells

International Journal of Radiation Oncology Biology Physics

Volumn 85, Issue 2, 2013, Pages 466-471

  Zheng, Zhiming ^a,b   Wang, Ping ^b   Wang, Hongyan ^b   Zhang, Xiangming ^b   Wang, Minli ^c   Cucinotta, Francis A ^d   Wang, Ya ^b  

^a SHANDONG UNIVERSITY   (China)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITIES SPACE RESEARCH ASSOCIATION   (United States)

^d NASA JOHNSON SPACE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL MODEL; BRAIN TUMORS; CELL LINES; CLONOGENIC ASSAYS; HOMOLOGOUS RECOMBINATION; HUMAN TUMOR CELLS; IN-VITRO; ION RADIATION; LUNG CANCER CELLS; MICRORNAS; NONHOMOLOGOUS END JOINING; NUDE MICE; TUMOR AREAS; TUMOR CELLS; TUMOR SIZE;

BIOLOGICAL MATERIALS; CELL CULTURE; CELL DEATH; REPAIR; TUMORS; X RAYS;

HEAVY IONS;

MICRORNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER SIZE; CELL SURVIVAL; CONTROLLED STUDY; GENE OVEREXPRESSION; HEAVY ION RADIATION; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; X RAY; XENOGRAFT;

ANIMALS; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; COMBINED MODALITY THERAPY; DNA-BINDING PROTEINS; HEAVY IONS; HUMANS; MALE; MICE; MICRORNAS; RADIATION TOLERANCE; RECOMBINATIONAL DNA REPAIR; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84872183669     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2012.04.008     Document Type: Article

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