-
1
-
-
45149100665
-
Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: A report from the international workshop on chronic lymphocytic leukemia updating the national cancer institute-working group 1996 guidelines
-
Hallek M, Cheson BD, Catovsky D, et al. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines. Blood 2008;111:5446-56
-
(2008)
Blood
, vol.111
, pp. 5446-56
-
-
Hallek, M.1
Cheson, B.D.2
Catovsky, D.3
-
2
-
-
78651376557
-
New anti-cd20 monoclonal antibodies for the treatment of b-cell lymphoid malignancies
-
Robak T, Robak E. New anti-CD20 monoclonal antibodies for the treatment of B-cell lymphoid malignancies. BioDrugs 2011;25:13-24
-
(2011)
BioDrugs
, vol.25
, pp. 13-24
-
-
Robak, T.1
Robak, E.2
-
3
-
-
0019448991
-
A unique cell surface antigen identifying lymphoid malignancies of B cell origin
-
Nadler LM, Ritz J, Hardy R, et al. A unique cell surface antigen identifying lymphoid malignancies of B cell origin. J Clin Invest 1981;67:134-40 (Pubitemid 11163165)
-
(1981)
Journal of Clinical Investigation
, vol.67
, Issue.1
, pp. 134-140
-
-
Nadler, L.M.1
Ritz, J.2
Hardy, R.3
-
4
-
-
79952720110
-
The future of anti-cd20 monoclonal antibodies: Are we making progress?
-
Alduaij W, Illidge TM. The future of anti-CD20 monoclonal antibodies: are we making progress? Blood 2011;117:2993-3001
-
(2011)
Blood
, vol.117
, pp. 2993-3001
-
-
Alduaij, W.1
Illidge, T.M.2
-
5
-
-
51649093353
-
Long-term results of the fludarabine, cyclophosphamide, and rituximab regimen as initial therapy of chronic lymphocytic leukemia
-
Tam CS, O'Brien S, Wierda W, et al. Long-term results of the fludarabine, cyclophosphamide, and rituximab regimen as initial therapy of chronic lymphocytic leukemia. Blood 2008;112:975-80
-
(2008)
Blood
, vol.112
, pp. 975-80
-
-
Tam, C.S.1
O'Brien, S.2
Wierda, W.3
-
6
-
-
77957664665
-
Addition of rituximab to fludarabine and cyclophosphamide in patients with chronic lymphocytic leukaemia: A randomised, open-label, phase 3 trial
-
Landmark randomized trial showing that addition of rituximab to FC improved outcomes in untreated CLL patients.
-
Hallek M, Fischer K, Fingerle-Rowson G, et al. Addition of rituximab to fludarabine and cyclophosphamide in patients with chronic lymphocytic leukaemia: a randomised, open-label, phase 3 trial. Lancet 2010;376:1164-74 Landmark randomized trial showing that addition of rituximab to FC improved outcomes in untreated CLL patients.
-
(2010)
Lancet
, vol.376
, pp. 1164-74
-
-
Hallek, M.1
Fischer, K.2
Fingerle-Rowson, G.3
-
7
-
-
77950502126
-
Ofatumumab as single-Agent cd20 immunotherapy in fludarabine-refractory chronic lymphocytic leukemia
-
Wierda WG, Kipps TJ, Mayer J, et al. Ofatumumab as single-Agent CD20 immunotherapy in fludarabine-refractory chronic lymphocytic leukemia. J Clin Oncol 2010;28:1749-54
-
(2010)
J Clin Oncol
, vol.28
, pp. 1749-54
-
-
Wierda, W.G.1
Kipps, T.J.2
Mayer, J.3
-
8
-
-
84858664440
-
Rituximab for chronic lymphocytic leukemia
-
Robak T. Rituximab for chronic lymphocytic leukemia. Expert Opin Biol Ther 2012;12:503-14
-
(2012)
Expert Opin Biol Ther
, vol.12
, pp. 503-14
-
-
Robak, T.1
-
9
-
-
77949423291
-
Strategies to enhance rituximab anti-tumor activity in the treatment of cd20-positive b-cell neoplasms
-
Riaz W, Hernandez-Ilizaliturri FJ, Czuczman MS. Strategies to enhance rituximab anti-tumor activity in the treatment of CD20-positive B-cell neoplasms. Immunol Res 2010;46:192-204
-
(2010)
Immunol Res
, vol.46
, pp. 192-204
-
-
Riaz, W.1
Hernandez-Ilizaliturri, F.J.2
Czuczman, M.S.3
-
10
-
-
41349113572
-
FMC7 is an epitope of CD20
-
DOI 10.1182/blood-2007-11-126243
-
Deans JP, Polyak MJ. FMC7 is an epitope of CD20. Blood 2008;111:2492; author reply 3-4 (Pubitemid 351451473)
-
(2008)
Blood
, vol.111
, Issue.4
, pp. 2492
-
-
Deans, J.P.1
Polyak, M.J.2
-
11
-
-
0242363627
-
Diagnostic significance of CD20 and FMC7 expression in B-cell disorders
-
DOI 10.1309/FNGC-YEMJ-E3MA-E5L2
-
Delgado J, Matutes E, Morilla AM, et al. Diagnostic significance of CD20 and FMC7 expression in B-cell disorders. Am J Clin Pathol 2003;120:754-9 (Pubitemid 37339684)
-
(2003)
American Journal of Clinical Pathology
, vol.120
, Issue.5
, pp. 754-759
-
-
Delgado, J.1
Matutes, E.2
Morilla, A.M.3
Morilla, R.M.4
Owusu-Ankomah, K.A.5
Rafiq-Mohammed, F.6
Del Giudice, I.7
Catovsky, D.8
-
12
-
-
77950331000
-
Cd20 as a target for therapeutic type i and ii monoclonal antibodies
-
Beers SA, Chan CH, French RR, et al. CD20 as a target for therapeutic type I and II monoclonal antibodies. Semin Hematol 2010;47:107-14
-
(2010)
Semin Hematol
, vol.47
, pp. 107-14
-
-
Beers, S.A.1
Chan, C.H.2
French, R.R.3
-
13
-
-
0029115799
-
Association of 75/80-kda phosphoproteins and the tyrosine kinases lyn, fyn, and lck with the b cell molecule cd20. Evidence against involvement of the cytoplasmic regions of cd20
-
Deans JP, Kalt L, Ledbetter JA, et al. Association of 75/80-kDa phosphoproteins and the tyrosine kinases Lyn, Fyn, and Lck with the B cell molecule CD20. Evidence against involvement of the cytoplasmic regions of CD20. J Biol Chem 1995;270:22632-8
-
(1995)
J Biol Chem
, vol.270
, pp. 22632-8
-
-
Deans, J.P.1
Kalt, L.2
Ledbetter, J.A.3
-
14
-
-
0031858988
-
The association between CD20 and Src-family tyrosine kinases requires an additional factor
-
DOI 10.1016/S0161-5890(98)00042-X, PII S016158909800042X
-
Popoff IJ, Savage JA, Blake J, et al. The association between CD20 and Src-family Tyrosine kinases requires an additional factor. Mol Immunol 1998;35:207-14 (Pubitemid 28374928)
-
(1998)
Molecular Immunology
, vol.35
, Issue.4
, pp. 207-214
-
-
Popoff, I.J.1
Savage, J.A.2
Blake, J.3
Johnson, P.4
Deans, J.P.5
-
15
-
-
79960475243
-
Cd20 antibodies: Doing the time warp
-
Cragg MS. CD20 antibodies: doing the time warp. Blood 2011;118:219-20
-
(2011)
Blood
, vol.118
, pp. 219-20
-
-
Cragg, M.S.1
-
16
-
-
0031813122
-
Mice carrying a CD20 gene disruption
-
DOI 10.1007/s002510050412
-
O'Keefe TL, Williams GT, Davies SL, Neuberger MS. Mice carrying a CD20 gene disruption. Immunogenetics 1998;48:125-32 (Pubitemid 28302315)
-
(1998)
Immunogenetics
, vol.48
, Issue.2
, pp. 125-132
-
-
O'Keefe, T.L.1
Williams, G.T.2
Davies, S.L.3
Neuberger, M.S.4
-
17
-
-
0346728609
-
Mouse CD20 expression and function
-
DOI 10.1093/intimm/dxh009
-
Uchida J, Lee Y, Hasegawa M, et al. Mouse CD20 expression and function. Int Immunol 2004;16:119-29 (Pubitemid 38054633)
-
(2004)
International Immunology
, vol.16
, Issue.1
, pp. 119-129
-
-
Uchida, J.1
Lee, Y.2
Hasegawa, M.3
Liang, Y.4
Bradney, A.5
Oliver, J.A.6
Bowen, K.7
Steeber, D.A.8
Haas, K.M.9
Poe, J.C.10
Tedder, T.F.11
-
18
-
-
77955300283
-
Ofatumumab, a novel anti-cd20 monoclonal antibody for the treatment of b-cell malignancies
-
Cheson BD. Ofatumumab, a novel anti-CD20 monoclonal antibody for the treatment of B-cell malignancies. J Clin Oncol 2010;28:3525-30
-
(2010)
J Clin Oncol
, vol.28
, pp. 3525-30
-
-
Cheson, B.D.1
-
19
-
-
33745324686
-
The biological activity of human CD20 monoclonal antibodies is linked to unique epitopes on CD20
-
Teeling JL, Mackus WJ, Wiegman LJ, et al. The biological activity of human CD20 monoclonal antibodies is linked to unique epitopes on CD20. J Immunol 2006;177:362-71 (Pubitemid 43939148)
-
(2006)
Journal of Immunology
, vol.177
, Issue.1
, pp. 362-371
-
-
Teeling, J.L.1
Mackus, W.J.M.2
Wiegman, L.J.J.M.3
Van Den Brakel, J.H.N.4
Beers, S.A.5
French, R.R.6
Van Meerten, T.7
Ebeling, S.8
Vink, T.9
Slootstra, J.W.10
Parren, P.W.H.I.11
Glennie, M.J.12
Van De Winkel, J.G.J.13
-
20
-
-
0034775122
-
Variability in B-cell antigen expression: Implications for the treatment of B-cell lymphomas and leukemias with monoclonal antibodies
-
DOI 10.1038/sj.thj.6200119
-
Rossmann ED, Lundin J, Lenkei R, et al. Variability in B-cell antigen expression: implications for the treatment of B-cell lymphomas and leukemias with monoclonal antibodies. Hematol J 2001;2:300-6 (Pubitemid 32976373)
-
(2001)
Hematology Journal
, vol.2
, Issue.5
, pp. 300-306
-
-
Rossmann, E.D.1
Lundin, J.2
Lenkei, R.3
Mellstedt, H.4
Osterborg, A.5
-
21
-
-
0042346042
-
Complement activation determines the therapeutic activity of rituximab in vivo
-
Di Gaetano N, Cittera E, Nota R, et al. Complement activation determines the therapeutic activity of rituximab in vivo. J Immunol 2003;171:1581-7 (Pubitemid 36900094)
-
(2003)
Journal of Immunology
, vol.171
, Issue.3
, pp. 1581-1587
-
-
Di Gaetano, N.1
Cittera, E.2
Nota, R.3
Vecchi, A.4
Grieco, V.5
Scanziani, E.6
Botto, M.7
Introna, M.8
Golay, J.9
-
22
-
-
58149162030
-
Type ii (tositumomab) anti-cd20 monoclonal antibody out performs type i (rituximab-like) reagents in b-cell depletion regardless of complement activation
-
Beers SA, Chan CH, James S, et al. Type II (tositumomab) anti-CD20 monoclonal antibody out performs type I (rituximab-like) reagents in B-cell depletion regardless of complement activation. Blood 2008;112:4170-7
-
(2008)
Blood
, vol.112
, pp. 4170-7
-
-
Beers, S.A.1
Chan, C.H.2
James, S.3
-
23
-
-
42149090514
-
Complement activation plays a key role in antibody-induced infusion toxicity in monkeys and rats
-
Tawara T, Hasegawa K, Sugiura Y, et al. Complement activation plays a key role in antibody-induced infusion toxicity in monkeys and rats. J Immunol 2008;180:2294-8
-
(2008)
J Immunol
, vol.180
, pp. 2294-8
-
-
Tawara, T.1
Hasegawa, K.2
Sugiura, Y.3
-
24
-
-
38949121647
-
NK-cell activation and antibody-dependent cellular cytotoxicity induced by rituximab-coated target cells is inhibited by the C3b component of complement
-
DOI 10.1182/blood-2007-02-074716
-
Wang SY, Racila E, Taylor RP, Weiner GJ. NK-cell activation and antibody-dependent cellular cytotoxicity induced by rituximab-coated target cells is inhibited by the C3b component of complement. Blood 2008;111:1456-63 (Pubitemid 351213433)
-
(2008)
Blood
, vol.111
, Issue.3
, pp. 1456-1463
-
-
Wang, S.-Y.1
Racila, E.2
Taylor, R.P.3
Weiner, G.J.4
-
25
-
-
0038518572
-
Apoptotic-regulatory and complement-protecting protein expression in chronic lymphocytic leukemia: Relationship to in vivo rituximab resistance
-
DOI 10.1200/JCO.2003.06.012
-
Bannerji R, Kitada S, Flinn IW, et al. Apoptotic-regulatory and complement-protecting protein expression in chronic lymphocytic leukemia: relationship to in vivo rituximab resistance. J Clin Oncol 2003;21:1466-71 (Pubitemid 46594097)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.8
, pp. 1466-1471
-
-
Bannerji, R.1
Kitada, S.2
Flinn, I.W.3
Pearson, M.4
Young, D.5
Reed, J.C.6
Byrd, J.C.7
-
26
-
-
3042592452
-
The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy
-
DOI 10.1084/jem.20040119
-
Uchida J, Hamaguchi Y, Oliver JA, et al. The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy. J Exp Med 2004;199:1659-69 (Pubitemid 38821999)
-
(2004)
Journal of Experimental Medicine
, vol.199
, Issue.12
, pp. 1659-1669
-
-
Uchida, J.1
Hamaguchi, Y.2
Oliver, J.A.3
Ravetch, J.V.4
Poe, J.C.5
Haas, K.M.6
Tedder, T.F.7
-
27
-
-
0842264005
-
FcγRIIIa and FcγRIIa polymorphisms do not predict response to rituximab in B-cell chronic lymphocytic leukemia
-
DOI 10.1182/blood-2003-07-2548
-
Farag SS, Flinn IW, Modali R, et al. Fc gamma RIIIa and Fc gamma RIIa polymorphisms do not predict response to rituximab in B-cell chronic lymphocytic leukemia. Blood 2004;103:1472-4 (Pubitemid 38168664)
-
(2004)
Blood
, vol.103
, Issue.4
, pp. 1472-1474
-
-
Farag, S.S.1
Flinn, I.W.2
Modali, R.3
Lehman, T.A.4
Young, D.5
Byrd, J.C.6
-
28
-
-
68849108368
-
Monoclonal antibodies directed to cd20 and hla-dr can elicit homotypic adhesion followed by lysosome-mediated cell death in human lymphoma and leukemia cells
-
Ivanov A, Beers SA, Walshe CA, et al. Monoclonal antibodies directed to CD20 and HLA-DR can elicit homotypic adhesion followed by lysosome-mediated cell death in human lymphoma and leukemia cells. J Clin Invest 2009;119:2143-59
-
(2009)
J Clin Invest
, vol.119
, pp. 2143-59
-
-
Ivanov, A.1
Beers, S.A.2
Walshe, C.A.3
-
29
-
-
77956545725
-
Long-lasting antitumor protection by anti-cd20 antibody through cellular immune response
-
Abes R, Gelize E, Fridman WH, Teillaud JL. Long-lasting antitumor protection by anti-CD20 antibody through cellular immune response. Blood 2010;116:926-34
-
(2010)
Blood
, vol.116
, pp. 926-34
-
-
Abes, R.1
Gelize, E.2
Fridman, W.H.3
Teillaud, J.L.4
-
30
-
-
78751564397
-
Preclinical studies on the mechanism of action and the anti-lymphoma activity of the novel anti-cd20 antibody ga101
-
Dalle S, Reslan L, Besseyre de Horts T, et al. Preclinical studies on the mechanism of action and the anti-lymphoma activity of the novel anti-CD20 antibody GA101. Mol Cancer Ther 2011;10:178-84
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 178-84
-
-
Dalle, S.1
Reslan, L.2
Besseyre De Horts, T.3
-
31
-
-
0037306946
-
Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid rafts
-
DOI 10.1182/blood-2002-06-1761
-
Cragg MS, Morgan SM, Chan HT, et al. Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid rafts. Blood 2003;101:1045-52 (Pubitemid 36139378)
-
(2003)
Blood
, vol.101
, Issue.3
, pp. 1045-1052
-
-
Cragg, M.S.1
Morgan, S.M.2
Chan, H.T.C.3
Morgan, B.P.4
Filatov, A.V.5
Johnson, P.W.M.6
French, R.R.7
Glennie, M.J.8
-
32
-
-
0141704595
-
CD20-induced lymphoma cell death is independent of both caspases and its redistribution into triton X-100 insoluble membrane rafts
-
Chan HT, Hughes D, French RR, et al. CD20-induced lymphoma cell death is independent of both caspases and its redistribution into triton X-100 insoluble membrane rafts. Cancer Res 2003;63:5480-9 (Pubitemid 37139867)
-
(2003)
Cancer Research
, vol.63
, Issue.17
, pp. 5480-5489
-
-
Chan, H.T.C.1
Hughes, D.2
French, R.R.3
Tutt, A.L.4
Walshe, C.A.5
Teeling, J.L.6
Glennie, M.J.7
Cragg, M.S.8
-
33
-
-
50949166628
-
Radiation therapy with tositumomab (b1) anti-cd20 monoclonal antibody initiates extracellular signal-regulated kinase/mitogen-Activated protein kinase-dependent cell death that overcomes resistance to apoptosis
-
Ivanov A, Krysov S, Cragg MS, Illidge T. Radiation therapy with tositumomab (B1) anti-CD20 monoclonal antibody initiates extracellular signal-regulated kinase/mitogen-Activated protein kinase-dependent cell death that overcomes resistance to apoptosis. Clin Cancer Res 2008;14:4925-34
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4925-34
-
-
Ivanov, A.1
Krysov, S.2
Cragg, M.S.3
Illidge, T.4
-
34
-
-
78651232150
-
Bm-ca is a newly defined type i/ii anti-cd20 monoclonal antibody with unique biological properties
-
Nishida M, Uematsu N, Kobayashi H, et al. BM-ca is a newly defined type I/II anti-CD20 monoclonal antibody with unique biological properties. Int J Oncol 2011;38:335-44
-
(2011)
Int J Oncol
, vol.38
, pp. 335-44
-
-
Nishida, M.1
Uematsu, N.2
Kobayashi, H.3
-
35
-
-
33746833616
-
Bone marrow histopathological and molecular changes of small B-cell lymphomas after rituximab therapy: Comparison with clinical response and patients' outcome
-
Goteri G, Olivieri A, Ranaldi R, et al. Bone marrow histopathological and molecular changes of small B-cell lymphomas after rituximab therapy: comparison with clinical response and patients outcome. Int J Immunopathol Pharmacol 2006;19:421-31 (Pubitemid 44181964)
-
(2006)
International Journal of Immunopathology and Pharmacology
, vol.19
, Issue.2
, pp. 421-431
-
-
Goteri, G.1
Olivieri, A.2
Ranaldi, R.3
Lucesole, M.4
Filosa, A.5
Capretti, R.6
Pieramici, T.7
Leoni, P.8
Rubini, C.9
Fabris, G.10
Lo Muzio, L.11
-
36
-
-
40949136882
-
Acquirement of rituximab resistance in lymphoma cell lines is associated with both global CD20 gene and protein down-regulation regulated at the pretranscriptional and posttranscriptional levels
-
DOI 10.1158/1078-0432.CCR-07-1254
-
Czuczman MS, Olejniczak S, Gowda A, et al. Acquirement of rituximab resistance in lymphoma cell lines is associated with both global CD20 gene and protein down-regulation regulated at the pretranscriptional and posttranscriptional levels. Clin Cancer Res 2008;14:1561-70 (Pubitemid 351413941)
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.5
, pp. 1561-1570
-
-
Czuczman, M.S.1
Olejniczak, S.2
Gowda, A.3
Kotowski, A.4
Binder, A.5
Kaur, H.6
Knight, J.7
Starostik, P.8
Deans, J.9
Hernandez-Ilizaliturri, F.J.10
-
38
-
-
66549111370
-
Down-regulation of cd20 expression in b-cell lymphoma cells after treatment with rituximab-containing combination chemotherapies: Its prevalence and clinical significance
-
Hiraga J, Tomita A, Sugimoto T, et al. Down-regulation of CD20 expression in B-cell lymphoma cells after treatment with rituximab-containing combination chemotherapies: its prevalence and clinical significance. Blood 2009;113:4885-93
-
(2009)
Blood
, vol.113
, pp. 4885-93
-
-
Hiraga, J.1
Tomita, A.2
Sugimoto, T.3
-
39
-
-
32044464340
-
The shaving reaction: Rituximab/CD20 complexes are removed from mantle cell lymphoma and chronic lymphocytic leukemia cells by THP-1 monocytes
-
Beum PV, Kennedy AD, Williams ME, et al. The shaving reaction: rituximab/CD20 complexes are removed from mantle cell lymphoma and chronic lymphocytic leukemia cells by THP-1 monocytes. J Immunol 2006;176:2600-9 (Pubitemid 43201712)
-
(2006)
Journal of Immunology
, vol.176
, Issue.4
, pp. 2600-2609
-
-
Beum, P.V.1
Kennedy, A.D.2
Williams, M.E.3
Lindorfer, M.A.4
Taylor, R.P.5
-
40
-
-
77954679392
-
Antigenic modulation limits the efficacy of anti-cd20 antibodies: Implications for antibody selection
-
Beers SA, French RR, Chan HT, et al. Antigenic modulation limits the efficacy of anti-CD20 antibodies: implications for antibody selection. Blood 2010;115:5191-201
-
(2010)
Blood
, vol.115
, pp. 5191-201
-
-
Beers, S.A.1
French, R.R.2
Chan, H.T.3
-
41
-
-
33750816429
-
Thrice-weekly low-dose rituximab decreases CD20 loss via shaving and promotes enhanced targeting in chronic lymphocytic leukemia
-
Williams ME, Densmore JJ, Pawluczkowycz AW, et al. Thrice-weekly low-dose rituximab decreases CD20 loss via shaving and promotes enhanced targeting in chronic lymphocytic leukemia. J Immunol 2006;177:7435-43 (Pubitemid 44715114)
-
(2006)
Journal of Immunology
, vol.177
, Issue.10
, pp. 7435-7443
-
-
Williams, M.E.1
Densmore, J.J.2
Pawluczkowycz, A.W.3
Beum, P.V.4
Kennedy, A.D.5
Lindorfer, M.A.6
Hamil, S.H.7
Eggleton, J.C.8
Taylor, R.P.9
-
42
-
-
0028057250
-
Depletion of b cells in vivo by a chimeric mouse human monoclonal antibody to cd20
-
Reff ME, Carner K, Chambers KS, et al. Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20. Blood 1994;83:435-44
-
(1994)
Blood
, vol.83
, pp. 435-44
-
-
Reff, M.E.1
Carner, K.2
Chambers, K.S.3
-
43
-
-
78650064032
-
Prospective analysis of hepatitis b virus reactivation in patients with diffuse large b-cell lymphoma after rituximab combination chemotherapy
-
Niitsu N, Hagiwara Y, Tanae K, et al. Prospective analysis of hepatitis B virus reactivation in patients with diffuse large B-cell lymphoma after rituximab combination chemotherapy. J Clin Oncol 2010;28:5097-100
-
(2010)
J Clin Oncol
, vol.28
, pp. 5097-100
-
-
Niitsu, N.1
Hagiwara, Y.2
Tanae, K.3
-
44
-
-
67749087489
-
The late adverse events of rituximab therapy-rare but there!
-
Ram R, Ben-Bassat I, Shpilberg O, et al. The late adverse events of rituximab therapy-rare but there! Leuk Lymphoma. 2009;50:1083-94
-
(2009)
Leuk Lymphoma
, vol.50
, pp. 1083-94
-
-
Ram, R.1
Ben-Bassat, I.2
Shpilberg, O.3
-
45
-
-
1842368507
-
Idec-c2b8 (rituximab) anti-cd20 monoclonal antibody therapy in patients with relapsed low-grade non-hodgkin's lymphoma
-
Maloney DG, Grillo-Lopez AJ, White CA, et al. IDEC-C2B8 (Rituximab) anti-CD20 monoclonal antibody therapy in patients with relapsed low-grade non-Hodgkin's lymphoma. Blood 1997;90:2188-94
-
(1997)
Blood
, vol.90
, pp. 2188-94
-
-
Maloney, D.G.1
Grillo-Lopez, A.J.2
White, C.A.3
-
46
-
-
0032931320
-
IDEC-C2B8 anti-CD20 (Rituximab) immunotherapy in patients with low- grade non-Hodgkin's lymphoma and lymphoproliferative disorders: Evaluation of response on 48 patients
-
Nguyen DT, Amess JA, Doughty H, et al. IDEC-C2B8 anti-CD20 (rituximab) immunotherapy in patients with low-grade non-Hodgkin's lymphoma and lymphoproliferative disorders: evaluation of response on 48 patients. Eur J Haematol 1999;62:76-82 (Pubitemid 29071265)
-
(1999)
European Journal of Haematology
, vol.62
, Issue.2
, pp. 76-82
-
-
Nguyen, D.T.1
Amess, J.A.2
Doughty, H.3
Hendry, L.4
Diamond, L.W.5
-
47
-
-
0026655066
-
Reduced expression of cd20 antigen as a characteristic marker for chronic lymphocytic leukemia
-
Almasri NM, Duque RE, Iturraspe J, et al. Reduced expression of CD20 antigen as a characteristic marker for chronic lymphocytic leukemia. Am J Hematol 1992;40:259-63
-
(1992)
Am J Hematol
, vol.40
, pp. 259-63
-
-
Almasri, N.M.1
Duque, R.E.2
Iturraspe, J.3
-
48
-
-
0035871445
-
Rituximab using a thrice weekly dosing schedule in B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma demonstrates clinical activity and acceptable toxicity
-
Byrd JC, Murphy T, Howard RS, et al. Rituximab using a thrice weekly dosing schedule in B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma demonstrates clinical activity and acceptable toxicity. J Clin Oncol 2001;19:2153-64 (Pubitemid 32366969)
-
(2001)
Journal of Clinical Oncology
, vol.19
, Issue.8
, pp. 2153-2164
-
-
Byrd, J.C.1
Murphy, T.2
Howard, R.S.3
Lucas, M.S.4
Goodrich, A.5
Park, K.6
Pearson, M.7
Waselenko, J.K.8
Ling, G.9
Grever, M.R.10
Grillo-Lopez, A.J.11
Rosenberg, J.12
Kunkel, L.13
Flinn, I.W.14
-
49
-
-
0035871441
-
Rituximab dose-escalation trial in chronic lymphocytic leukemia
-
O'Brien SM, Kantarjian H, Thomas DA, et al. Rituximab dose-escalation trial in chronic lymphocytic leukemia. J Clin Oncol 2001;19:2165-70 (Pubitemid 32366970)
-
(2001)
Journal of Clinical Oncology
, vol.19
, Issue.8
, pp. 2165-2170
-
-
O'Brien, S.M.1
Kantarjian, H.2
Thomas, D.A.3
Giles, F.J.4
Freireich, E.J.5
Cortes, J.6
Lerner, S.7
Keating, M.J.8
-
50
-
-
79951658129
-
Single agent rituxan in early stage chronic lymphocytic leukemia(cll)
-
[abstract]
-
Thomas DA, O'Brien S, Giles FJ, et al. Single agent rituxan in early stage chronic lymphocytic leukemia(CLL) [abstract]. Blood 2001;98:364
-
(2001)
Blood
, vol.98
, pp. 364
-
-
Thomas, D.A.1
O'Brien, S.2
Giles, F.J.3
-
51
-
-
0038811776
-
Single-agent rituximab as first-line and maintenance treatment for patients with chronic lymphocytic leukemia or small lymphocytic lymphoma: A phase II trial of the Minnie Pearl Cancer Research Network
-
DOI 10.1200/JCO.2003.09.027
-
Hainsworth JD, Litchy S, Barton JH, et al. Single-Agent rituximab as first-line and maintenance treatment for patients with chronic lymphocytic leukemia or small lymphocytic lymphoma: a phase II trial of the Minnie Pearl Cancer Research Network. J Clin Oncol 2003;21:1746-51 (Pubitemid 46638587)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.9
, pp. 1746-1751
-
-
Hainsworth, J.D.1
Litchy, S.2
Barton, J.H.3
Houston, G.A.4
Hermann, R.C.5
Bradof, J.E.6
Greco, F.A.7
-
52
-
-
0034894958
-
Inhibition of interleukin 10 by Rituximab results in down-regulation of Bcl-2 and sensitization of B-cell non-Hodgkin's lymphoma to apoptosis
-
Alas S, Emmanouilides C, Bonavida B. Inhibition of interleukin 10 by rituximab results in down-regulation of bcl-2 and sensitization of B-cell non-Hodgkin's lymphoma to apoptosis. Clin Cancer Res 2001;7:709-23 (Pubitemid 32707998)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.3
, pp. 709-723
-
-
Alas, S.1
Emmanouilides, C.2
Bonavida, B.3
-
53
-
-
0036839469
-
Phase 2 study of a combined immunochemotherapy using rituximab and fludarabine in patients with chronic lymphocytic leukemia
-
DOI 10.1182/blood-2002-03-0972
-
Schulz H, Klein SK, Rehwald U, et al. Phase 2 study of a combined immunochemotherapy using rituximab and fludarabine in patients with chronic lymphocytic leukemia. Blood 2002;100:3115-20 (Pubitemid 35217057)
-
(2002)
Blood
, vol.100
, Issue.9
, pp. 3115-3120
-
-
Schulz, H.1
Klein, S.K.2
Rehwald, U.3
Reiser, M.4
Hinke, A.5
Knauf, W.-U.6
Aulitzky, W.-E.7
Hensel, M.8
Herold, M.9
Huhn, D.10
Hallek, M.11
Diehl, V.12
Engert, A.13
-
54
-
-
29144449249
-
The addition of rituximab to fludarabine improves clinical outcome in untreated patients with ZAP-70-negative chronic lymphocytic leukemia
-
DOI 10.1002/cncr.21535
-
Del Poeta G, Del Principe MI, Consalvo MA, et al. The addition of rituximab to fludarabine improves clinical outcome in untreated patients with ZAP-70-negative chronic lymphocytic leukemia. Cancer 2005;104:2743-52 (Pubitemid 41798284)
-
(2005)
Cancer
, vol.104
, Issue.12
, pp. 2743-2752
-
-
Del Poeta, G.1
Del Principe, M.I.2
Irno Consalvo, M.A.3
Maurillo, L.4
Buccisano, F.5
Venditti, A.6
Mazzone, C.7
Bruno, A.8
Gianni, L.9
Capelli, G.10
Lo Coco, F.11
Cantonetti, M.12
Gattei, V.13
Amadori, S.14
-
55
-
-
0037220152
-
Randomized phase 2 study of fludarabine with concurrent versus sequential treatment with rituximab in symptomatic, untreated patients with B-cell chronic lymphocytic leukemia: Results from cancer and leukemia group B 9712 (CALGB 9712)
-
DOI 10.1182/blood-2002-04-1258
-
Byrd JC, Peterson BL, Morrison VA, et al. Randomized phase 2 study of fludarabine with concurrent versus sequential treatment with rituximab in symptomatic, untreated patients with B-cell chronic lymphocytic leukemia: results from Cancer and Leukemia Group B 9712 (CALGB 9712). Blood 2003;101:6-14 (Pubitemid 36025880)
-
(2003)
Blood
, vol.101
, Issue.1
, pp. 6-14
-
-
Byrd, J.C.1
Peterson, B.L.2
Morrison, V.A.3
Park, K.4
Jacobson, R.5
Hoke, E.6
Vardiman, J.W.7
Rai, K.8
Schiffer, C.A.9
Larson, R.A.10
-
56
-
-
19944429446
-
Addition of rituximab to fludarabine may prolong progression-free survival and overall survival in patients with previously untreated chronic lymphocytic leukemia: An updated retrospective comparative analysis of CALGB 9712 and CALGB 9011
-
DOI 10.1182/blood-2004-03-0796
-
Byrd JC, Rai K, Peterson BL, et al. Addition of rituximab to fludarabine may prolong progression-free survival and overall survival in patients with previously untreated chronic lymphocytic leukemia: an updated retrospective comparative analysis of CALGB 9712 and CALGB 9011. Blood 2005;105:49-53 (Pubitemid 40053062)
-
(2005)
Blood
, vol.105
, Issue.1
, pp. 49-53
-
-
Byrd, J.C.1
Rai, K.2
Peterson, B.L.3
Appelbaum, F.R.4
Morrison, V.A.5
Kolitz, J.E.6
Shepherd, L.7
Hines, J.D.8
Schiffer, C.A.9
Larson, R.A.10
-
57
-
-
79954435811
-
Chemoimmunotherapy with fludarabine and rituximab produces extended overall survival and progression-free survival in chronic lymphocytic leukemia: Long-term followup of calgb study 9712
-
Woyach JA, Ruppert AS, Heerema NA, et al. Chemoimmunotherapy with fludarabine and rituximab produces extended overall survival and progression-free survival in chronic lymphocytic leukemia: long-term followup of CALGB study 9712. J Clin Oncol 2011;29:1349-54
-
(2011)
J Clin Oncol
, vol.29
, pp. 1349-54
-
-
Woyach, J.A.1
Ruppert, A.S.2
Heerema, N.A.3
-
58
-
-
0035179950
-
DNA repair initiated in chronic lymphocytic leukemia lymphocytes by 4-hydroperoxycyclophosphamide is inhibited by fludarabine and clofarabine
-
Yamauchi T, Nowak BJ, Keating MJ, Plunkett W. DNA repair initiated in chronic lymphocytic leukemia lymphocytes by 4-hydroperoxycyclophosphamide is inhibited by fludarabine and clofarabine. Clin Cancer Res 2001;7:3580-9 (Pubitemid 33069998)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.11
, pp. 3580-3589
-
-
Yamauchi, T.1
Nowak, B.J.2
Keating, M.J.3
Plunkett, W.4
-
59
-
-
77956972088
-
Baff serum level predicts time to first treatment in early chronic lymphocytic leukemia
-
Molica S, Digiesi G, Battaglia C, et al. Baff serum level predicts time to first treatment in early chronic lymphocytic leukemia. Eur J Haematol 2010;85:314-20
-
(2010)
Eur J Haematol
, vol.85
, pp. 314-20
-
-
Molica, S.1
Digiesi, G.2
Battaglia, C.3
-
60
-
-
23044510136
-
Early results of a chemoimmunotherapy regimen of fludarabine, cyclophosphamide, and rituximab as initial therapy for chronic lymphocytic leukemia
-
DOI 10.1200/JCO.2005.12.051
-
Keating MJ, O'Brien S, Albitar M, et al. Early results of a chemoimmunotherapy regimen of fludarabine, cyclophosphamide, and rituximab as initial therapy for chronic lymphocytic leukemia. J Clin Oncol 2005;23:4079-88 Pioneering study showing results of FCR as frontline therapy (Pubitemid 46211313)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.18
, pp. 4079-4088
-
-
Keating, M.J.1
O'Brien, S.2
Albitar, M.3
Lerner, S.4
Plunkett, W.5
Giles, F.6
Andreeff, M.7
Cortes, J.8
Faderl, S.9
Thomas, D.10
Koller, C.11
Wierda, W.12
Detry, M.A.13
Lynn, A.14
Kantarjian, H.15
-
61
-
-
84860630561
-
Minimal residual disease quantification is an independent predictor of progression-free and overall survival in chronic lymphocytic leukemia: A multivariate analysis from the randomized gcllsg cll8 trial
-
Bottcher S, Ritgen M, Fischer K, et al. Minimal residual disease quantification is an independent predictor of progression-free and overall survival in chronic lymphocytic leukemia: a multivariate analysis from the randomized GCLLSG CLL8 trial. J Clin Oncol 2012;30:980-8
-
(2012)
J Clin Oncol
, vol.30
, pp. 980-8
-
-
Bottcher, S.1
Ritgen, M.2
Fischer, K.3
-
62
-
-
59149090791
-
Chemoimmunotherapy with low-dose fludarabine and cyclophosphamide and high dose rituximab in previously untreated patients with chronic lymphocytic leukemia
-
Foon KA, Boyiadzis M, Land SR, et al. Chemoimmunotherapy with low-dose fludarabine and cyclophosphamide and high dose rituximab in previously untreated patients with chronic lymphocytic leukemia. J Clin Oncol 2009;27:498-503
-
(2009)
J Clin Oncol
, vol.27
, pp. 498-503
-
-
Foon, K.A.1
Boyiadzis, M.2
Land, S.R.3
-
63
-
-
84859344298
-
Long-term results of chemoimmunotherapy with low-dose fludarabine, cyclophosphamide and high-dose rituximab as initial treatment for patients with chronic lymphocytic leukemia
-
Foon KA, Mehta D, Lentzsch S, et al. Long-term results of chemoimmunotherapy with low-dose fludarabine, cyclophosphamide and high-dose rituximab as initial treatment for patients with chronic lymphocytic leukemia. Blood 2012;119:3184-4
-
(2012)
Blood
, vol.119
, pp. 3184-4
-
-
Foon, K.A.1
Mehta, D.2
Lentzsch, S.3
-
64
-
-
59149106873
-
Sequential therapy with fludarabine, high-dose cyclophosphamide, and rituximab in previously untreated patients with chronic lymphocytic leukemia produces high-quality responses: Molecular remissions predict for durable complete responses
-
Lamanna N, Jurcic JG, Noy A, et al. Sequential therapy with fludarabine, high-dose cyclophosphamide, and rituximab in previously untreated patients with chronic lymphocytic leukemia produces high-quality responses: molecular remissions predict for durable complete responses. J Clin Oncol 2009;27:491-7
-
(2009)
J Clin Oncol
, vol.27
, pp. 491-7
-
-
Lamanna, N.1
Jurcic, J.G.2
Noy, A.3
-
65
-
-
33846258434
-
Combination chemoimmunotherapy with pentostatin, cyclophosphamide, and rituximab shows significant clinical activity with low accompanying toxicity in previously untreated B chronic lymphocytic leukemia
-
DOI 10.1182/blood-2006-07-033274
-
Kay NE, Geyer SM, Call TG, et al. Combination chemoimmunotherapy with pentostatin, cyclophosphamide, and rituximab shows significant clinical activity with low accompanying toxicity in previously untreated B chronic lymphocytic leukemia. Blood 2007;109:405-11 (Pubitemid 46105933)
-
(2007)
Blood
, vol.109
, Issue.2
, pp. 405-411
-
-
Kay, N.E.1
Geyer, S.M.2
Call, T.G.3
Shanafelt, T.D.4
Zent, C.S.5
Jelinek, D.F.6
Tschumper, R.7
Bone, N.D.8
Dewald, G.W.9
Lin, T.S.10
Heerema, N.A.11
Smith, L.12
Grever, M.R.13
Byrd, J.C.14
-
66
-
-
74549145611
-
Rituximab, fludarabine, cyclophosphamide, and mitoxantrone: A new, highly active chemoimmunotherapy regimen for chronic lymphocytic leukemia
-
Bosch F, Abrisqueta P, Villamor N, et al. Rituximab, fludarabine, cyclophosphamide, and mitoxantrone: a new, highly active chemoimmunotherapy regimen for chronic lymphocytic leukemia. J Clin Oncol 2009;27:4578-84
-
(2009)
J Clin Oncol
, vol.27
, pp. 4578-84
-
-
Bosch, F.1
Abrisqueta, P.2
Villamor, N.3
-
67
-
-
84866531516
-
Bendamustine in combination with rituximab for previously untreated patients with chronic lymphocytic leukemia: A multicenter phase ii trial of the german chronic lymphocytic leukemia study group
-
Fischer K, Cramer P, Busch R, et al. Bendamustine in combination with rituximab for previously untreated patients with chronic lymphocytic leukemia: a multicenter phase II trial of the German Chronic Lymphocytic Leukemia Study Group. J Clin Oncol 2012;30(26):3209-16
-
(2012)
J Clin Oncol
, vol.30
, Issue.26
, pp. 3209-16
-
-
Fischer, K.1
Cramer, P.2
Busch, R.3
-
68
-
-
84861342267
-
Rituximab plus chlorambucil as initial treatment for elderly patients with chronic lymphocytic leukemia (cll): Effect of pre-treatment biological characteristics and gene expression patterns on response to treatment [abstract]
-
Foa R, Ciolli S, Raimondo FD, et al. Rituximab plus chlorambucil as initial treatment for elderly patients with chronic lymphocytic leukemia (CLL): effect of pre-treatment biological characteristics and gene expression patterns on response to treatment [abstract]. Blood 2011;118:1
-
(2011)
Blood
, vol.118
, pp. 1
-
-
Foa, R.1
Ciolli, S.2
Raimondo, F.D.3
-
69
-
-
84872182150
-
-
German CLL Study Group NCIN, ClinicalTrials.gov NCT00769522. Fludarabine, Cyclophosphamide, and Rituximab or Bendamustine and Rituximab in Treating Patients With Previously Untreated B-Cell Chronic Lymphocytic Leukemia. Available from:
-
German CLL Study Group NCIN, ClinicalTrials.gov NCT00769522. Fludarabine, Cyclophosphamide, and Rituximab or Bendamustine and Rituximab in Treating Patients With Previously Untreated B-Cell Chronic Lymphocytic Leukemia. Available from: http://clinicaltrialsgov/ct2/results?term=NCT00769522 2012
-
(2012)
-
-
-
70
-
-
80052180048
-
Frontline chemoimmunotherapy with fludarabine, cyclophosphamide, alemtuzumab, and rituximab for high-risk chronic lymphocytic leukemia
-
Parikh SA, Keating MJ, O'Brien S, et al. Frontline chemoimmunotherapy with fludarabine, cyclophosphamide, alemtuzumab, and rituximab for high-risk chronic lymphocytic leukemia. Blood 2011;118:2062-8
-
(2011)
Blood
, vol.118
, pp. 2062-8
-
-
Parikh, S.A.1
Keating, M.J.2
O'Brien, S.3
-
71
-
-
77449133613
-
Phase 1/2 study of lumiliximab combined with fludarabine, cyclophosphamide, and rituximab in patients with relapsed or refractory chronic lymphocytic leukemia
-
Byrd JC, Kipps TJ, Flinn IW, et al. Phase 1/2 study of lumiliximab combined with fludarabine, cyclophosphamide, and rituximab in patients with relapsed or refractory chronic lymphocytic leukemia. Blood 2010;115:489-94
-
(2010)
Blood
, vol.115
, pp. 489-94
-
-
Byrd, J.C.1
Kipps, T.J.2
Flinn, I.W.3
-
72
-
-
84864336293
-
A phase iii trial of fludarabine, cyclophosphamide, and rituximab vs. Pentostatin, cyclophosphamide, and rituximab in b-cell chronic lymphocytic leukemia
-
Reynolds C, Di Bella N, Lyons RM, et al. A phase III trial of fludarabine, cyclophosphamide, and rituximab vs. pentostatin, cyclophosphamide, and rituximab in B-cell chronic lymphocytic leukemia. Invest New Drugs 2012;30:1232-40
-
(2012)
Invest New Drugs
, vol.30
, pp. 1232-40
-
-
Reynolds, C.1
Di Bella, N.2
Lyons, R.M.3
-
73
-
-
77950478885
-
Rituximab plus fludarabine and cyclophosphamide prolongs progression-free survival compared with fludarabine and cyclophosphamide alone in previously treated chronic lymphocytic leukemia
-
Robak T, Dmoszynska A, Solal-Celigny P, et al. Rituximab plus fludarabine and cyclophosphamide prolongs progression-free survival compared with fludarabine and cyclophosphamide alone in previously treated chronic lymphocytic leukemia. J Clin Oncol 2010;28:1756-64
-
(2010)
J Clin Oncol
, vol.28
, pp. 1756-64
-
-
Robak, T.1
Dmoszynska, A.2
Solal-Celigny, P.3
-
74
-
-
80053020928
-
Bendamustine combined with rituximab in patients with relapsed and/or refractory chronic lymphocytic leukemia: A multicenter phase ii trial of the german chronic lymphocytic leukemia study group
-
Fischer K, Cramer P, Busch R, et al. Bendamustine combined with rituximab in patients with relapsed and/or refractory chronic lymphocytic leukemia: a multicenter phase II trial of the German Chronic Lymphocytic Leukemia Study Group. J Clin Oncol 2011;29:3559-66
-
(2011)
J Clin Oncol
, vol.29
, pp. 3559-66
-
-
Fischer, K.1
Cramer, P.2
Busch, R.3
-
75
-
-
79953072637
-
Fludarabine, cyclophosphamide, and rituximab chemoimmunotherapy is highly effective treatment for relapsed patients with cll
-
Badoux XC, Keating MJ, Wang X, et al. Fludarabine, cyclophosphamide, and rituximab chemoimmunotherapy is highly effective treatment for relapsed patients with CLL. Blood 2011;117:3016-24
-
(2011)
Blood
, vol.117
, pp. 3016-24
-
-
Badoux, X.C.1
Keating, M.J.2
Wang, X.3
-
76
-
-
33645732715
-
Pentostatin, cyclophosphamide, and rituximab is an active, well-tolerated regimen for patients with previously treated chronic lymphocytic leukemia
-
DOI 10.1200/JCO.2005.04.3836
-
Lamanna N, Kalaycio M, Maslak P, et al. Pentostatin, cyclophosphamide, and rituximab is an active, well-tolerated regimen for patients with previously treated chronic lymphocytic leukemia. J Clin Oncol 2006;24:1575-81 (Pubitemid 46638781)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.10
, pp. 1575-1581
-
-
Lamanna, N.1
Kalaycio, M.2
Maslak, P.3
Jurcic, J.G.4
Heaney, M.5
Brentjens, R.6
Zelenetz, A.D.7
Horgan, D.8
Gencarelli, A.9
Panageas, K.S.10
Scheinberg, D.A.11
Weiss, M.A.12
-
77
-
-
33749600951
-
Rituximab combined with cladribine or with cladribine and cyclophosphamide in heavily pretreated patients with indolent lymphoproliferative disorders and mantle cell lymphoma
-
DOI 10.1002/cncr.22196
-
Robak T, Smolewski P, Cebula B, et al. Rituximab combined with cladribine or with cladribine and cyclophosphamide in heavily pretreated patients with indolent lymphoproliferative disorders and mantle cell lymphoma. Cancer 2006;107:1542-50 (Pubitemid 44546915)
-
(2006)
Cancer
, vol.107
, Issue.7
, pp. 1542-1550
-
-
Robak, T.1
Smolewski, P.2
Cebula, B.3
Szmigielska-Kaplon, A.4
Chojnowski, K.5
Blonski, J.Z.6
-
78
-
-
70350132633
-
Rituximab in combination with high-dose methylprednisolone for the treatment of chronic lymphocytic leukemia
-
Castro JE, James DF, Sandoval-Sus JD, et al. Rituximab in combination with high-dose methylprednisolone for the treatment of chronic lymphocytic leukemia. Leukemia 2009;23:1779-89
-
(2009)
Leukemia
, vol.23
, pp. 1779-89
-
-
Castro, J.E.1
James, D.F.2
Sandoval-Sus, J.D.3
-
79
-
-
40849094878
-
High dose methylprednisolone and rituximab is an effective therapy in advanced refractory chronic lymphocytic leukemia resistant to fludarabine therapy
-
DOI 10.3324/haematol.11903
-
Dungarwalla M, Evans SO, Riley U, et al. High dose methylprednisolone and rituximab is an effective therapy in advanced refractory chronic lymphocytic leukemia resistant to fludarabine therapy. Haematologica 2008;93:475-6 (Pubitemid 351398657)
-
(2008)
Haematologica
, vol.93
, Issue.3
, pp. 475-476
-
-
Dungarwalla, M.1
Evans, S.O.2
Riley, U.3
Catovsky, D.4
Dearden, C.E.5
Matutes, E.6
-
80
-
-
37149029392
-
Methylprednisolone-rituximab is an effective salvage therapy for patients with relapsed chronic lymphocytic leukemia including those with unfavorable cytogenetic features
-
DOI 10.1080/10428190701724801, PII 788239125
-
Bowen DA, Call TG, Jenkins GD, et al. Methylprednisolone-rituximab is an effective salvage therapy for patients with relapsed chronic lymphocytic leukemia including those with unfavorable cytogenetic features. Leuk Lymphoma 2007;48:2412-17 (Pubitemid 350253473)
-
(2007)
Leukemia and Lymphoma
, vol.48
, Issue.12
, pp. 2412-2417
-
-
Bowen, D.A.1
Call, T.G.2
Jenkins, G.D.3
Zent, C.Z.4
Schwager, S.M.5
Van Dyke, D.L.6
Jelinek, D.F.7
Kay, N.E.8
Shanafelt, T.D.9
-
81
-
-
79957456534
-
Dose-dense high-dose methylprednisolone and rituximab in the treatment of relapsed or refractory high-risk chronic lymphocytic leukemia
-
Pileckyte R, Jurgutis M, Valceckiene V, et al. Dose-dense high-dose methylprednisolone and rituximab in the treatment of relapsed or refractory high-risk chronic lymphocytic leukemia. Leuk Lymphoma 2011;52:1055-64
-
(2011)
Leuk Lymphoma
, vol.52
, pp. 1055-64
-
-
Pileckyte, R.1
Jurgutis, M.2
Valceckiene, V.3
-
82
-
-
84865173645
-
Rituximab in combination with high-dose dexamethasone for the treatment of relapsed/refractory chronic lymphocytic leukemia
-
Smolej L, Doubek M, Panovska A, et al. Rituximab in combination with high-dose dexamethasone for the treatment of relapsed/refractory chronic lymphocytic leukemia. Leuk Res 2012;36:1278-82
-
(2012)
Leuk Res
, vol.36
, pp. 1278-82
-
-
Smolej, L.1
Doubek, M.2
Panovska, A.3
-
83
-
-
78650823247
-
Rituximab maintenance for 2 years in patients with high tumour burden follicular lymphoma responding to rituximab plus chemotherapy (prima): A phase 3, randomised controlled trial
-
Salles G, Seymour JF, Offner F, et al. Rituximab maintenance for 2 years in patients with high tumour burden follicular lymphoma responding to rituximab plus chemotherapy (PRIMA): a phase 3, randomised controlled trial. Lancet 2011;377:42-51
-
(2011)
Lancet
, vol.377
, pp. 42-51
-
-
Salles, G.1
Seymour, J.F.2
Offner, F.3
-
84
-
-
37549046061
-
Consolidation and maintenance immunotherapy with rituximab improve clinical outcome in patients with b-cell chronic lymphocytic leukemia
-
Del Poeta G, Del Principe MI, Buccisano F, et al. Consolidation and maintenance immunotherapy with rituximab improve clinical outcome in patients with B-cell chronic lymphocytic leukemia. Cancer 2008;112:119-28
-
(2008)
Cancer
, vol.112
, pp. 119-28
-
-
Del Poeta, G.1
Del Principe, M.I.2
Buccisano, F.3
-
85
-
-
84859719803
-
Rituximab maintenance in patients with chronic lymphocytic leukemia (cll) after upfront treatment with rituximab plus fludarabine, cyclophosphamide, and mitoxantrone (r-fcm): Final results of a multicenter phase ii trial on behalf of the spanish cll study group (gellc) [abstract]
-
Bosch F, Abrisqueta P, Villamor N, et al. Rituximab maintenance in patients with chronic lymphocytic leukemia (CLL) after upfront treatment with rituximab plus fludarabine, cyclophosphamide, and mitoxantrone (R-FCM): final results of a multicenter phase II trial on behalf of the Spanish CLL study group (GELLC) [abstract]. Blood 2011;118:293
-
(2011)
Blood
, vol.118
, pp. 293
-
-
Bosch, F.1
Abrisqueta, P.2
Villamor, N.3
-
86
-
-
10744230768
-
Anti-cd20 therapy for chronic lymphocytic leukemia-Associated autoimmune diseases
-
Zaja F, Vianelli N, Sperotto A, et al. Anti-CD20 therapy for chronic lymphocytic leukemia-Associated autoimmune diseases. Leuk Lymphoma 2003;44:1951-4
-
(2003)
Leuk Lymphoma
, vol.44
, pp. 1951-4
-
-
Zaja, F.1
Vianelli, N.2
Sperotto, A.3
-
87
-
-
68449102378
-
A combination of rituximab, cyclophosphamide and dexamethasone effectively treats immune cytopenias of chronic lymphocytic leukemia
-
Kaufman M, Limaye SA, Driscoll N, et al. A combination of rituximab, cyclophosphamide and dexamethasone effectively treats immune cytopenias of chronic lymphocytic leukemia. Leuk Lymphoma 2009;50:892-9
-
(2009)
Leuk Lymphoma
, vol.50
, pp. 892-9
-
-
Kaufman, M.1
Limaye, S.A.2
Driscoll, N.3
-
88
-
-
79952445044
-
Rituximab-cyclophosphamidedexamethasone combination in the management of autoimmune cytopenias associated with chronic lymphocytic leukemia
-
Rossignol J, Michallet AS, Oberic L, et al. Rituximab- cyclophosphamidedexamethasone combination in the management of autoimmune cytopenias associated with chronic lymphocytic leukemia. Leukemia 2011;25:473-8
-
(2011)
Leukemia
, vol.25
, pp. 473-8
-
-
Rossignol, J.1
Michallet, A.S.2
Oberic, L.3
-
89
-
-
77953199483
-
Treatment of autoimmune cytopenia complicating progressive chronic lymphocytic leukemia/small lymphocytic lymphoma with rituximab, cyclophosphamide, vincristine, and prednisone
-
Bowen DA, Call TG, Shanafelt TD, et al. Treatment of autoimmune cytopenia complicating progressive chronic lymphocytic leukemia/small lymphocytic lymphoma with rituximab, cyclophosphamide, vincristine, and prednisone. Leuk Lymphoma 2010;51:620-7
-
(2010)
Leuk Lymphoma
, vol.51
, pp. 620-7
-
-
Bowen, D.A.1
Call, T.G.2
Shanafelt, T.D.3
-
90
-
-
84861344593
-
A phase 1 study of the selective phosphatidylinositol 3-kinase-delta (pi3k) inhibitor cal-101 (gs-1101), in combination with rituximab and/or bendamustine in patients with relapsed or refractory chronic lymphocytic leukemia (cll) [abstract]
-
Sharman J, de Vos S, Leonard JP, et al. A Phase 1 Study of the Selective Phosphatidylinositol 3-Kinase-Delta (PI3K) Inhibitor, CAL-101 (GS-1101), in Combination with Rituximab and/or Bendamustine in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) [abstract]. Blood 2011;118:1787
-
(2011)
Blood
, vol.118
, pp. 1787
-
-
Sharman, J.1
De Vos, S.2
Leonard, J.P.3
-
91
-
-
84867231194
-
Final analysis of a phase 2 study of lenalidomide and rituximab in patients with relapsed or refractory chronic lymphocytic leukemia (cll) [abstract]
-
Badoux X, Keating M, O'Brien S, et al. Final Analysis of a Phase 2 Study of Lenalidomide and Rituximab in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) [abstract]. Blood 2011;118:980
-
(2011)
Blood
, vol.118
, pp. 980
-
-
Badoux, X.1
Keating, M.2
O'Brien, S.3
-
92
-
-
84867232551
-
A phase iii trial of fludarabine bendamustine and rituximab (fbr) chemoimmunotherapy for previously treated patients with cll [abstract]
-
Wierda W, Balakrishnan K, Ferrajoli A, et al. A Phase I/II Trial of Fludarabine, Bendamustine, and Rituximab (FBR) Chemoimmunotherapy for Previously Treated Patients with CLL [abstract]. Blood 2011;118:3901
-
(2011)
Blood
, vol.118
, pp. 3901
-
-
Wierda, W.1
Balakrishnan, K.2
Ferrajoli, A.3
-
93
-
-
4444343395
-
Characterization of new human CD20 monoclonal antibodies with potent cytolytic activity against non-Hodgkin lymphomas
-
DOI 10.1182/blood-2004-01-0039
-
Teeling JL, French RR, Cragg MS, et al. Characterization of new human CD20 monoclonal antibodies with potent cytolytic activity against non-Hodgkin lymphomas. Blood 2004;104:1793-800 (Pubitemid 39202289)
-
(2004)
Blood
, vol.104
, Issue.6
, pp. 1793-1800
-
-
Teeling, J.L.1
French, R.R.2
Cragg, M.S.3
Van Den Brakel, J.4
Pluyter, M.5
Huang, H.6
Chan, C.7
Parren, P.W.H.I.8
Hack, C.E.9
Dechant, M.10
Valerius, T.11
Van De Winkel, J.G.J.12
Glennie, M.J.13
-
94
-
-
84856249903
-
Ofatumumab demonstrates activity against rituximab-sensitive and -resistant cell lines, lymphoma xenografts and primary tumour cells from patients with b-cell lymphoma
-
Barth MJ, Hernandez-Ilizaliturri FJ, Mavis C, et al. Ofatumumab demonstrates activity against rituximab-sensitive and -resistant cell lines, lymphoma xenografts and primary tumour cells from patients with B-cell lymphoma. Br J Haematol 2012;156:490-8
-
(2012)
Br J Haematol
, vol.156
, pp. 490-8
-
-
Barth, M.J.1
Hernandez-Ilizaliturri, F.J.2
Mavis, C.3
-
95
-
-
73949084380
-
Characterization of a rituximab variant with potent antitumor activity against rituximab-resistant b-cell lymphoma
-
Li B, Zhao L, Guo H, et al. Characterization of a rituximab variant with potent antitumor activity against rituximab-resistant B-cell lymphoma. Blood 2009;114:5007-14
-
(2009)
Blood
, vol.114
, pp. 5007-14
-
-
Li, B.1
Zhao, L.2
Guo, H.3
-
96
-
-
38349138517
-
Estimation of dose requirements for sustained in vivo activity of a therapeutic human anti-cd20 antibody
-
Bleeker WK, Munk ME, Mackus WJ, et al. Estimation of dose requirements for sustained in vivo activity of a therapeutic human anti-CD20 antibody. Br J Haematol 2008;140:303-12
-
(2008)
Br J Haematol
, vol.140
, pp. 303-12
-
-
Bleeker, W.K.1
Munk, M.E.2
Mackus, W.J.3
-
97
-
-
84855814866
-
Combination therapy with ofatumumab and bendamustine in xenograft model of chronic lymphocytic leukaemia
-
Haskova Z, Whitacre MN, Dede KA, et al. Combination therapy with ofatumumab and bendamustine in xenograft model of chronic lymphocytic leukaemia. Br J Haematol 2012;156:402-4
-
(2012)
Br J Haematol
, vol.156
, pp. 402-4
-
-
Haskova, Z.1
Whitacre, M.N.2
Dede, K.A.3
-
98
-
-
38949185742
-
Safety and efficacy of ofatumumab, a fully human monoclonal anti-CD20 antibody, in patients with relapsed or refractory B-cell chronic lymphocytic leukemia: A phase 1-2 study
-
DOI 10.1182/blood-2007-09-111781
-
Coiffier B, Lepretre S, Pedersen LM, et al. Safety and efficacy of ofatumumab, a fully human monoclonal anti-CD20 antibody, in patients with relapsed or refractory B-cell chronic lymphocytic leukemia: a phase 1-2 study. Blood 2008;111:1094-100 (Pubitemid 351213387)
-
(2008)
Blood
, vol.111
, Issue.3
, pp. 1094-1100
-
-
Coiffier, B.1
Lepretre, S.2
Pedersen, L.M.3
Gadeberg, O.4
Fredriksen, H.5
Van Oers, M.H.J.6
Wooldridge, J.7
Kloczko, J.8
Holowiecki, J.9
Hellmann, A.10
Walewski, J.11
Flensburg, M.12
Petersen, J.13
Robak, T.14
-
99
-
-
79955870406
-
Final analysis from the international trial of single-Agent ofatumumab in patients with fludarabine-refractory chronic lymphocytic leukemia
-
Wierda WG, Kipps TJ, Mayer J, et al. Final Analysis From the International Trial of Single-Agent Ofatumumab In Patients with Fludarabine-Refractory Chronic Lymphocytic Leukemia. ASH Annual Meeting Abstracts; 2010. p. 116
-
(2010)
ASH Annual Meeting Abstracts
, pp. 116
-
-
Wierda, W.G.1
Kipps, T.J.2
Mayer, J.3
-
101
-
-
81055148076
-
Ofatumumab is active in patients with fludarabine-refractory cll irrespective of prior rituximab: Results from the phase 2 international study
-
Wierda WG, Padmanabhan S, Chan GW, Gupta IV. Ofatumumab is active in patients with fludarabine-refractory CLL irrespective of prior rituximab: results from the phase 2 international study. Blood 2011;118:5126-9
-
(2011)
Blood
, vol.118
, pp. 5126-9
-
-
Wierda, W.G.1
Padmanabhan, S.2
Chan, G.W.3
Gupta, I.V.4
-
102
-
-
84872188413
-
Ofatumumab retreatment and maintenance in patients with fludarabine-refractory cll
-
Osterborg A, Martin JSD, Jiri M, et al. Ofatumumab retreatment and maintenance in patients with fludarabine-refractory CLL. ASCO; 2012
-
(2012)
ASCO
-
-
Osterborg, A.1
Martin, J.S.D.2
Jiri, M.3
-
103
-
-
84867230849
-
Combination therapy with ofatumumab and lenalidomide in patients with relapsed chronic lymphocytic leukemia ( cll): Results of a phase ii trial
-
Ferrajoli A, O'Brien S, Wierda W, et al. Combination Therapy with Ofatumumab and Lenalidomide in Patients with Relapsed Chronic Lymphocytic Leukemia (CLL): Results of a Phase II Trial. ASH; 2011
-
(2011)
ASH
-
-
Ferrajoli, A.1
O'Brien, S.2
Wierda, W.3
-
104
-
-
84872486370
-
Efficacy of ofatumumab and high-dose methylprednisolone for the treatment of relapsed or refractory chronic lymphocytic leukemia (cll)
-
Teichman ML, Viet QH, et al. Efficacy of Ofatumumab and High-Dose Methylprednisolone for the Treatment of Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL). ASH Annual Meeting Abstracts; 2011. p. 118
-
(2011)
ASH Annual Meeting Abstracts
, pp. 118
-
-
Teichman, M.L.1
Viet, Q.H.2
-
105
-
-
84860738946
-
Oral high-dose glucocorticoids and ofatumumab in fludarabine-resistant chronic lymphocytic leukemia
-
Spaner DE. Oral high-dose glucocorticoids and Ofatumumab in fludarabine-resistant Chronic Lymphocytic Leukemia. Leukemia 2012;26:1144-4
-
(2012)
Leukemia
, vol.26
, pp. 1144-4
-
-
Spaner, D.E.1
-
106
-
-
84867234044
-
A phase ii trial of ofatumumab for older patients and patients who refuse fludarabine-based regimens with previously untreated chronic lymphocytic leukemia or small lymphocytic lymphoma
-
Flinn IW, Harwin WN, Macias-Pe'rez IM, et al. A Phase II Trial of Ofatumumab for Older Patients and Patients Who Refuse Fludarabine-Based Regimens with Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma. ASH Annual Meeting Abstracts; 2011. p. 118
-
(2011)
ASH Annual Meeting Abstracts
, pp. 118
-
-
Flinn, I.W.1
Harwin, W.N.2
Macias-Pe'rez, I.M.3
-
107
-
-
79959190996
-
Chemoimmunotherapy with o-fc in previously untreated patients with chronic lymphocytic leukemia
-
Wierda WG, Kipps TJ, Durig J, et al. Chemoimmunotherapy with O-FC in previously untreated patients with chronic lymphocytic leukemia. Blood 2011;117:6450-8
-
(2011)
Blood
, vol.117
, pp. 6450-8
-
-
Wierda, W.G.1
Kipps, T.J.2
Durig, J.3
-
108
-
-
84859740636
-
Ofatumumab based chemoimmunotherapy (cit) for patients with previously untreated cll
-
Shanafelt TD, Clive SZ, Lanasa MC, et al. Ofatumumab Based Chemoimmunotherapy (CIT) for Patients with Previously Untreated CLL. ASH Annual Meeting Abstracts; 2011. p. 118
-
(2011)
ASH Annual Meeting Abstracts
, pp. 118
-
-
Shanafelt, T.D.1
Clive, S.Z.2
Lanasa, M.C.3
-
109
-
-
84857349967
-
Obinutuzumab for the treatment of lymphoproliferative disorders
-
Owen C, Stewart DA. Obinutuzumab for the treatment of lymphoproliferative disorders. Expert Opin Biol Ther 2012;12:343-51
-
(2012)
Expert Opin Biol Ther
, vol.12
, pp. 343-51
-
-
Owen, C.1
Stewart, D.A.2
-
110
-
-
84861830510
-
A phase 1 study of obinutuzumab induction followed by 2 years of maintenance in patients with relapsed cd20-positive b-cell malignancies
-
Sehn LH, Assouline SE, Stewart DA, et al. A phase 1 study of obinutuzumab induction followed by 2 years of maintenance in patients with relapsed CD20-positive B-cell malignancies. Blood 2012;119:5118-24
-
(2012)
Blood
, vol.119
, pp. 5118-24
-
-
Sehn, L.H.1
Assouline, S.E.2
Stewart, D.A.3
-
111
-
-
80053055044
-
Chemoimmunotherapy with chlorambucil and the type ii cd20-Antibody ga101 in patients with chronic lymphocytic leukemia and comorbidity: Results of the run-in phase of the cll11 (bo21004) trial [abstract]
-
Valentin G, Kirsten F, Raymonde B, et al. Chemoimmunotherapy with Chlorambucil and the Type II CD20-Antibody GA101 In Patients with Chronic Lymphocytic Leukemia and Comorbidity: results of the Run-In Phase of the CLL11 (BO21004) Trial [abstract]. Blood 2010;116:1387
-
(2010)
Blood
, vol.116
, pp. 1387
-
-
Valentin, G.1
Kirsten, F.2
Raymonde, B.3
-
112
-
-
84857247431
-
Results from a phase ii study of obinutuzumab (ga101) monotherapy in relapsed/refractory chronic lymphocytic leukemia (cll). European hematology association annual congress [abstract]
-
Cartron G, Morschhauser F, Thieblemont C, et al. Results from a phase II study of obinutuzumab (GA101) monotherapy in relapsed/refractory chronic lymphocytic leukemia (CLL). European Hematology Association Annual Congress [abstract]. Haematologica 2011;96(s2):0101a
-
(2011)
Haematologica
, vol.96
, Issue.S2
-
-
Cartron, G.1
Morschhauser, F.2
Thieblemont, C.3
-
113
-
-
60849089338
-
Properties and structure-function relationships of veltuzumab (ha20), a humanized anti-cd20 monoclonal antibody
-
Goldenberg DM, Rossi EA, Stein R, et al. Properties and structure-function relationships of veltuzumab (hA20), a humanized anti-CD20 monoclonal antibody. Blood 2009;113:1062-70
-
(2009)
Blood
, vol.113
, pp. 1062-70
-
-
Goldenberg, D.M.1
Rossi, E.A.2
Stein, R.3
-
114
-
-
70249106098
-
Humanized anti-cd20 antibody, veltuzumab, in refractory/recurrent non-hodgkin's lymphoma: Phase i/ii results
-
Morschhauser F, Leonard JP, Fayad L, et al. Humanized anti-CD20 antibody, veltuzumab, in refractory/recurrent non-Hodgkin's lymphoma: phase I/II results. J Clin Oncol 2009;27:3346-53
-
(2009)
J Clin Oncol
, vol.27
, pp. 3346-53
-
-
Morschhauser, F.1
Leonard, J.P.2
Fayad, L.3
-
115
-
-
77955175014
-
Results of a phase i/ii study of ocrelizumab, a fully humanized anti-cd20 mab, in patients with relapsed/refractory follicular lymphoma
-
Morschhauser F, Marlton P, Vitolo U, et al. Results of a phase I/II study of ocrelizumab, a fully humanized anti-CD20 mAb, in patients with relapsed/refractory follicular lymphoma. Ann Oncol 2010;21:1870-6
-
(2010)
Ann Oncol
, vol.21
, Issue.6
-
-
Morschhauser, F.1
Marlton, P.2
Vitolo, U.3
-
116
-
-
56249095457
-
Rituximab in combination with high-dose methylprednisolone for the treatment of fludarabine refractory high-risk chronic lymphocytic leukemia
-
Castro JE, Sandoval-Sus JD, Bole J, Rassenti L. Rituximab in combination with high-dose methylprednisolone for the treatment of fludarabine refractory high-risk chronic lymphocytic leukemia. Leukemia 2008;22:2048-53
-
(2008)
Leukemia
, vol.22
, pp. 2048-53
-
-
Castro, J.E.1
Sandoval-Sus, J.D.2
Bole, J.3
Rassenti, L.4
|