Rituximab-cyclophosphamide-dexamethasone combination in the management of autoimmune cytopenias associated with chronic lymphocytic leukemia

Leukemia

Volumn 25, Issue 3, 2011, Pages 473-478

  Rossignol, J ^a   Michallet, A S ^b   Oberic, L ^c   Picard, M ^c   Garon, A ^b   Willekens, C ^c   Dulery, R ^a   Leleu, X ^a   Cazin, B ^a   Ysebaert, L ^c  

^a LILLE UNIVERSITY HOSPITAL   (France)

^b CENTRE HOSPITALIER LYON SUD   (France)

^c CHU PURPAN   (France)

Author keywords

AIHA; AITP; chronic lymphocytic leukemia; Evan's syndrome; PRCA; RCD

Indexed keywords

ALEMTUZUMAB; CHLORAMBUCIL; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DOXORUBICIN; FLUDARABINE; HEMOGLOBIN; PREDNISOLONE; PREDNISONE; RITUXIMAB; VINCRISTINE;

ADULT; AGED; ARTICLE; AUTOIMMUNE HEMOLYTIC ANEMIA; AUTOIMMUNITY; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; DIAGNOSTIC PROCEDURE; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE DURATION; DRUG SAFETY; DRUG TOLERABILITY; FEBRILE NEUTROPENIA; FEMALE; HUMAN; IDIOPATHIC THROMBOCYTOPENIC PURPURA; MALE; MULTIPLE CYCLE TREATMENT; PRIORITY JOURNAL; PURE RED CELL ANEMIA; RELAPSE; SPLENECTOMY; THROMBOCYTE COUNT;

EID: 79952445044     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2010.278     Document Type: Article

References (15)

1. Hamblin TJ. Autoimmune complications of chronic lymphocytic leukemia. Semin Oncol 2006; 33: 230-239. .
2. Karlsson C, Hansson L, Celsing F, Lundin J. Treatment of severe refractory autoimmune hemolytic anemia in B-cell chronic lymphocytic leukemia with alemtuzumab (humanized CD52 monoclonal antibody). Leukemia 2007; 21: 511-514. .
3. Hallek M, Cheson BD, Catovsky D, Caligaris-Capio F, Dighiero G, Döhner H et al. International workshop on chronic lymphocytic leukemia (2008) Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the international workshop on chronic lymphocytic leukemia updating the National Cancer Institute-working group 1996 guidelines. Blood 2008; 111: 5446-5456. .
4. Dearden C. Disease-specific complications of chronic lymphocytic leukemia. Hematology Am Soc Hematol Educ Program 2008; 2008: 450-456. .
5. Hall AM, Vickers MA, McLeod E, Barker RN. Rh autoantigen presentation to helper T cells in chronic lymphocytic leukemia by malignant B cells. Blood 2005; 105: 2007-2015. . (Pubitemid 40731785)
6. Gupta N, Kavuru S, Patel D, Janson D, Driscoll N, Ahmed S et al. Rituximab-based chemotherapy for steroid-refractory autoimmune hemolytic anemia of chronic lymphocytic leukemia. Leukemia 2002; 16: 2092-2095. . (Pubitemid 35203453)
7. Kaufman M, Limaye S, Driscoll N, Johnson C, Caramanica A, Lebowicz Y et al. A combination of rituximab, cyclophosphamide and dexamethasone effectively treats immune cytopenias of chronic lymphocytic leukemias. Leuk Lymphoma 2009; 50: 892-899. .
8. Bowen DA, Call TG, Shanafelt T, Kay N, Schwager S, Reinalda M et al. Treatment of autoimmune cytopenia complicating progressive chronic lymphocytic leukemia/small lymphocytic lymphoma with rituximab, cyclophosphamide, vincristine, and prednisone. Leuk Lymphoma 2010; 51: 620-627. .
9. Zent CS, Ding W, Schwager S, Reinalda M, Hoyer D, Jelinek D et al. The prognostic significance of cytopenia in chronic lymphocytic leukaemia/small lymphocytic lymphoma. Br J Haematol 2008; 141: 615-621. . (Pubitemid 351667621)
10. Mauro F, Foa R, Cerretti R, Giannarelli D, Coluzzi S, Girelli G. Autoimmune hemolytic anemia in chronic lymphocytic leukemia: clinical, therapeutic, and prognostic features. Blood 2000; 95: 2786-2792. . (Pubitemid 30235886)
11. Zent CS, Kay NE. Autoimmune complications in chronic lymphocytic leukemia. Best Pract Res Clin Haematol 2010; 23: 47-59. .
12. Visco C, Ruggeri M, Evangelista ML, Stasi R, Zanotti R, Giaretta I et al. Impact of immune thrombocytopenia on the clinical course of chronic lymphocytic leukemia. Blood 2008; 111: 1110-1116. . (Pubitemid 351213389)
13. Ghazal H. Successful treatment of pure red cell aplasia with rituximab in patients with chronic lymphocytic leukemia. Blood 2002; 99: 1092-1094. . (Pubitemid 34525578)
14. Narra K, Borghaei H, Al-Saleem T, Höglund M, Smith MR. Pure red cell aplasia in B-cell lymphoprliferative disorder treated with rituximab: report of two cases and review of the literature. Leukemia Res 2006; 30: 109-114. . (Pubitemid 41654714)
15. D'Arena G, Laurenti L, Capalbo S, D'Arco AM, De Filippi R, Marcacci G et al. Rituximab therapy for chronic lymphocytic leukemia-associated autoimmune hemolytic anemia. Am J Hematol 2006; 81: 598-602. (Pubitemid 44066170)