Mice with an adipocyte-specific lipin 1 separation-of-function allele reveal unexpected roles for phosphatidic acid in metabolic regulation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 2, 2013, Pages 642-647

  Mitra, Mayurranjan S ^a   Chen, Zhouji ^a   Ren, Hongmei ^b   Harris, Thurl E ^c   Chambers, Kari T ^a   Hall, Angela M ^a   Nadra, Karim ^d   Klein, Samuel ^a   Chrast, Roman ^d   Su, Xiong ^a   Morris, Andrew J ^b   Finck, Brian N ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

^d UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLGLYCEROL; CELL PROTEIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; LIPIN 1; LIPIN 2; PHOSPHATIDATE PHOSPHATASE; PHOSPHATIDIC ACID; PHOSPHODIESTERASE IV; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADIPOCYTE; ADIPOSE TISSUE; ALLELE; ARTICLE; ENZYME ACTIVITY; GENETIC RECOMBINATION; HYDROLYSIS; LIPID METABOLISM; LIPOGENESIS; LIPOLYSIS; METABOLIC REGULATION; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

3T3-L1 CELLS; ADIPOCYTES; ALLELES; ANIMALS; BLOTTING, WESTERN; CLONING, MOLECULAR; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; DNA PRIMERS; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GLYCERIDES; HUMANS; LIPOLYSIS; MALE; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NUCLEAR PROTEINS; OBESITY; PHOSPHATIDATE PHOSPHATASE; PHOSPHATIDIC ACIDS; REAL-TIME POLYMERASE CHAIN REACTION;

MUS;

EID: 84872178612     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1213493110     Document Type: Article

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