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Volumn 20, Issue 2, 2013, Pages 77-84

Hepatitis C virus diversity and hepatic steatosis

Author keywords

genotype; hepatic steatosis; hepatitis C virus; lipid droplet

Indexed keywords

MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; REACTIVE OXYGEN METABOLITE; STEROL REGULATORY ELEMENT BINDING PROTEIN;

EID: 84872138890     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/jvh.12035     Document Type: Review
Times cited : (50)

References (62)
  • 3
    • 70349247875 scopus 로고    scopus 로고
    • Sites and mechanisms of insulin resistance in nonobese, nondiabetic patients with chronic hepatitis C
    • Vanni E, Abate ML, Gentilcore E, et al,. Sites and mechanisms of insulin resistance in nonobese, nondiabetic patients with chronic hepatitis C. Hepatology 2009; 50: 697-706.
    • (2009) Hepatology , vol.50 , pp. 697-706
    • Vanni, E.1    Abate, M.L.2    Gentilcore, E.3
  • 4
    • 77449150552 scopus 로고    scopus 로고
    • Chronic hepatitis C is associated with peripheral rather than hepatic insulin resistance
    • Milner KL, van der Poorten D, Trenell M, et al,. Chronic hepatitis C is associated with peripheral rather than hepatic insulin resistance. Gastroenterology 2010; 138: 932-941.
    • (2010) Gastroenterology , vol.138 , pp. 932-941
    • Milner, K.L.1    Van Der Poorten, D.2    Trenell, M.3
  • 5
    • 77954378905 scopus 로고    scopus 로고
    • The importance of steatosis in chronic hepatitis C infection and its management
    • Cross TJ, Rashid MM, Berry PA, Harrison PM,. The importance of steatosis in chronic hepatitis C infection and its management. Hepatol Res 2010; 40: 237-247.
    • (2010) Hepatol Res , vol.40 , pp. 237-247
    • Cross, T.J.1    Rashid, M.M.2    Berry, P.A.3    Harrison, P.M.4
  • 7
    • 10744224572 scopus 로고    scopus 로고
    • Effect of antiviral treatment on evolution of liver steatosis in patients with chronic hepatitis C: Indirect evidence of a role of hepatitis C virus genotype 3 in steatosis
    • DOI 10.1136/gut.2002.009936
    • Castera L, Hezode C, Roudot-Thoraval F, et al,. Effect of antiviral treatment on evolution of liver steatosis in patients with chronic hepatitis C: indirect evidence of a role of hepatitis C virus genotype 3 in steatosis. Gut 2004; 53: 420-424. (Pubitemid 38241341)
    • (2004) Gut , vol.53 , Issue.3 , pp. 420-424
    • Castera, L.1    Hezode, C.2    Roudot-Thoraval, F.3    Lonjon, I.4    Zafrani, E.-S.5    Pawlotsky, J.-M.6    Dhumeaux, D.7
  • 8
    • 17044382863 scopus 로고    scopus 로고
    • An in vitro model of hepatitis C virus genotype 3a-associated triglyceride accumulation
    • Abid K, Pazienza V, de Gottardi A, et al,. An in vitro model of hepatitis C virus genotype 3a-associated triglyceride accumulation. J Hepatol 2005; 42: 744-751.
    • (2005) J Hepatol , vol.42 , pp. 744-751
    • Abid, K.1    Pazienza, V.2    De Gottardi, A.3
  • 9
    • 34548130208 scopus 로고    scopus 로고
    • The genotype 3-specific hepatitis C virus core protein residue phenylalanine 164 increases steatosis in an in vitro cellular model
    • DOI 10.1136/gut.2006.108647
    • Hourioux C, Patient R, Morin A, et al,. The genotype 3-specific hepatitis C virus core protein residue phenylalanine 164 increases steatosis in an in vitro cellular model. Gut 2007; 56: 1302-1308. (Pubitemid 47300434)
    • (2007) Gut , vol.56 , Issue.9 , pp. 1302-1308
    • Hourioux, C.1    Patient, R.2    Morin, A.3    Blanchard, E.4    Moreau, A.5    Trassard, S.6    Giraudeau, B.7    Roingeard, P.8
  • 10
    • 39149138470 scopus 로고    scopus 로고
    • Specific polymorphisms in hepatitis C virus genotype 3 core protein associated with intracellular lipid accumulation
    • DOI 10.1086/524846
    • Jhaveri R, McHutchison J, Patel K, Qiang G, Diehl AM,. Specific polymorphisms in hepatitis C virus genotype 3 core protein associated with intracellular lipid accumulation. J Infect Dis 2008; 197: 283-291. (Pubitemid 351263449)
    • (2008) Journal of Infectious Diseases , vol.197 , Issue.2 , pp. 283-291
    • Jhaveri, R.1    McHutchison, J.2    Patel, K.3    Qiang, G.4    Diehl, A.M.5
  • 12
    • 77956629698 scopus 로고    scopus 로고
    • Ultrastructural and quantitative analysis of the lipid droplet clustering induced by hepatitis C virus core protein
    • Depla M, Uzbekov R, Hourioux C, et al,. Ultrastructural and quantitative analysis of the lipid droplet clustering induced by hepatitis C virus core protein. Cell Mol Life Sci 2010; 67: 3151-3161.
    • (2010) Cell Mol Life Sci , vol.67 , pp. 3151-3161
    • Depla, M.1    Uzbekov, R.2    Hourioux, C.3
  • 13
    • 79955448291 scopus 로고    scopus 로고
    • The birth and life of lipid droplets: Learning from the hepatitis C virus
    • Roingeard P, Depla M,. The birth and life of lipid droplets: learning from the hepatitis C virus. Biol Cell 2011; 103: 223-231.
    • (2011) Biol Cell , vol.103 , pp. 223-231
    • Roingeard, P.1    Depla, M.2
  • 14
    • 78149359508 scopus 로고    scopus 로고
    • Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1
    • Herker E, Harris C, Hernandez C, et al,. Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. Nat Med 2010; 16: 1295-1298.
    • (2010) Nat Med , vol.16 , pp. 1295-1298
    • Herker, E.1    Harris, C.2    Hernandez, C.3
  • 15
    • 82755163055 scopus 로고    scopus 로고
    • Hepatitis C virus core protein decreases lipid droplet turnover: A mechanism for core-induced steatosis
    • Harris C, Herker E, Farese RV, Ott M,. Hepatitis C virus core protein decreases lipid droplet turnover: a mechanism for core-induced steatosis. J Biol Chem 2011; 286: 42615-42625.
    • (2011) J Biol Chem , vol.286 , pp. 42615-42625
    • Harris, C.1    Herker, E.2    Farese, R.V.3    Ott, M.4
  • 17
    • 50249107793 scopus 로고    scopus 로고
    • Hepatitis C virus budding at lipid droplet-associated ER membrane visualized by 3D electron microscopy
    • Roingeard P, Hourioux C, Blanchard E, Prensier G,. Hepatitis C virus budding at lipid droplet-associated ER membrane visualized by 3D electron microscopy. Histochem Cell Biol 2008; 130: 561-566.
    • (2008) Histochem Cell Biol , vol.130 , pp. 561-566
    • Roingeard, P.1    Hourioux, C.2    Blanchard, E.3    Prensier, G.4
  • 18
    • 38449108483 scopus 로고    scopus 로고
    • Hepatitis C virus core protein, lipid droplets and steatosis
    • DOI 10.1111/j.1365-2893.2007.00953.x
    • Roingeard P, Hourioux C,. Hepatitis C virus core protein, lipid droplets and steatosis. J Viral Hepat 2008; 15: 157-164. (Pubitemid 351143746)
    • (2008) Journal of Viral Hepatitis , vol.15 , Issue.3 , pp. 157-164
    • Roingeard, P.1    Hourioux, C.2
  • 21
    • 28844447277 scopus 로고    scopus 로고
    • Hepatitis C virus nonstructural proteins inhibit apolipoprotein B100 secretion
    • DOI 10.1074/jbc.M510391200
    • Domitrovich AM, Felmlee DJ, Siddiqui A,. Hepatitis C virus nonstructural proteins inhibit apolipoprotein B100 secretion. J Biol Chem 2005; 280: 39802-39808. (Pubitemid 41779113)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.48 , pp. 39802-39808
    • Domitrovich, A.M.1    Felmlee, D.J.2    Siddiqui, A.3
  • 22
    • 33644876665 scopus 로고    scopus 로고
    • Serum lipid pattern in chronic hepatitis C: Histological and virological correlations
    • Siagris D, Christofidou M, Theocharis GJ, et al,. Serum lipid pattern in chronic hepatitis C: histological and virological correlations. J Viral Hepat 2006; 13: 56-61.
    • (2006) J Viral Hepat , vol.13 , pp. 56-61
    • Siagris, D.1    Christofidou, M.2    Theocharis, G.J.3
  • 27
    • 34247636649 scopus 로고    scopus 로고
    • Up-regulation of fatty acid synthase promoter by hepatitis C virus core protein: Genotype-3a core has a stronger effect than genotype-1b core
    • Jackel-Cram C, Babiuk LA, Liu Q,. Up-regulation of fatty acid synthase promoter by hepatitis C virus core protein: genotype-3a core has a stronger effect than genotype-1b core. J Hepatol 2007; 46: 985-987.
    • (2007) J Hepatol , vol.46 , pp. 985-987
    • Jackel-Cram, C.1    Babiuk, L.A.2    Liu, Q.3
  • 28
    • 78149439794 scopus 로고    scopus 로고
    • Expression of genes involved in lipogenesis is not increased in patients with HCV genotype 3 in human liver
    • Ryan MC, Desmond PV, Slavin JL, Congiu M,. Expression of genes involved in lipogenesis is not increased in patients with HCV genotype 3 in human liver. J Viral Hepat 2011; 18: 53-60.
    • (2011) J Viral Hepat , vol.18 , pp. 53-60
    • Ryan, M.C.1    Desmond, P.V.2    Slavin, J.L.3    Congiu, M.4
  • 29
    • 34547097746 scopus 로고    scopus 로고
    • Hepatitis C virus induces proteolytic cleavage of sterol regulatory element binding proteins and stimulates their phosphorylation via oxidative stress
    • DOI 10.1128/JVI.00125-07
    • Waris G, Felmlee DJ, Negro F, Siddiqui A,. Hepatitis C virus induces proteolytic cleavage of sterol regulatory element binding proteins and stimulates their phosphorylation via oxidative stress. J Virol 2007; 81: 8122-8130. (Pubitemid 47101498)
    • (2007) Journal of Virology , vol.81 , Issue.15 , pp. 8122-8130
    • Waris, G.1    Felmlee, D.J.2    Negro, F.3    Siddiqui, A.4
  • 30
    • 44649115421 scopus 로고    scopus 로고
    • Activation of sterol regulatory element-binding protein 1c and fatty acid synthase transcription by hepatitis C virus non-structural protein 2
    • Oem JK, Jackel-Cram C, Li YP, et al,. Activation of sterol regulatory element-binding protein 1c and fatty acid synthase transcription by hepatitis C virus non-structural protein 2. J Gen Virol 2008; 89: 1225-1230.
    • (2008) J Gen Virol , vol.89 , pp. 1225-1230
    • Oem, J.K.1    Jackel-Cram, C.2    Li, Y.P.3
  • 31
    • 27844604269 scopus 로고    scopus 로고
    • Hepatitis C virus core protein inhibits mitochondrial electron transport and increases reactive oxygen species (ROS) production
    • DOI 10.1074/jbc.M506412200
    • Korenaga M, Wang T, Li Y, et al,. Hepatitis C virus core protein inhibits mitochondrial electron transport and increases reactive oxygen species (ROS) production. J Biol Chem 2005; 280: 37481-37488. (Pubitemid 41642356)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.45 , pp. 37481-37488
    • Korenaga, M.1    Wang, T.2    Li, Y.3    Showalter, L.A.4    Chan, T.5    Sun, J.6    Weinman, S.A.7
  • 32
    • 0036165333 scopus 로고    scopus 로고
    • Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein
    • Okuda M, Li K, Beard MR, et al,. Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein. Gastroenterology 2002; 122: 366-375. (Pubitemid 34116988)
    • (2002) Gastroenterology , vol.122 , Issue.2 , pp. 366-375
    • Okuda, M.1    Li, K.2    Beard, M.R.3    Showalter, L.A.4    Scholle, F.5    Lemon, S.M.6    Weinman, S.A.7
  • 33
    • 79959537058 scopus 로고    scopus 로고
    • Down-regulation of phosphatase and tensin homolog by hepatitis C virus core 3a in hepatocytes triggers the formation of large lipid droplets
    • Clément S, Peyrou M, Sanchez-Pareja A, et al,. Down-regulation of phosphatase and tensin homolog by hepatitis C virus core 3a in hepatocytes triggers the formation of large lipid droplets. Hepatology 2011; 54: 38-49.
    • (2011) Hepatology , vol.54 , pp. 38-49
    • Clément, S.1    Peyrou, M.2    Sanchez-Pareja, A.3
  • 34
    • 79960807577 scopus 로고    scopus 로고
    • Current understanding of insulin resistance in hepatitis C
    • Kaddai V, Negro F,. Current understanding of insulin resistance in hepatitis C. Expert Rev Gastroenterol Hepatol 2011; 5: 503-516.
    • (2011) Expert Rev Gastroenterol Hepatol , vol.5 , pp. 503-516
    • Kaddai, V.1    Negro, F.2
  • 35
    • 0033779703 scopus 로고    scopus 로고
    • Prevalence of type 2 diabetes mellitus among persons with hepatitis C virus infection in the United States
    • Mehta SH, Brancati FL, Sulkowski MS, Strathdee SA, Szklo M, Thomas DL,. Prevalence of type 2 diabetes mellitus among persons with hepatitis C virus infection in the United States. Ann Intern Med 2000; 133: 592-599.
    • (2000) Ann Intern Med , vol.133 , pp. 592-599
    • Mehta, S.H.1    Brancati, F.L.2    Sulkowski, M.S.3    Strathdee, S.A.4    Szklo, M.5    Thomas, D.L.6
  • 36
    • 84856474979 scopus 로고    scopus 로고
    • The interaction of metabolic factors with HCV infection: Does it matter?
    • Bugianesi E, Salamone F, Negro F,. The interaction of metabolic factors with HCV infection: does it matter? J Hepatol 2012; 56: S56-S65.
    • (2012) J Hepatol , vol.56
    • Bugianesi, E.1    Salamone, F.2    Negro, F.3
  • 37
    • 18244382304 scopus 로고    scopus 로고
    • Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
    • DOI 10.1172/JCI200523621
    • Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, Parks EJ,. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest 2005; 115: 1343-1351. (Pubitemid 40629054)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.5 , pp. 1343-1351
    • Donnelly, K.L.1    Smith, C.I.2    Schwarzenberg, S.J.3    Jessurun, J.4    Boldt, M.D.5    Parks, E.J.6
  • 40
    • 21044456174 scopus 로고    scopus 로고
    • Insulin resistance is a cause of steatosis and fibrosis progression in chronic hepatitis C
    • DOI 10.1136/gut.2004.050302
    • Fartoux L, Poujol-Robert A, Guéchot J, Wendum D, Poupon R, Serfaty L,. Insulin resistance is a cause of steatosis and fibrosis progression in chronic hepatitis C. Gut 2005; 54: 1003-1008. (Pubitemid 40873917)
    • (2005) Gut , vol.54 , Issue.7 , pp. 1003-1008
    • Fartoux, L.1    Poujol-Robert, A.2    Guechot, J.3    Wendum, D.4    Poupon, R.5    Serfaty, L.6
  • 43
    • 47149095922 scopus 로고    scopus 로고
    • Morphological changes in intracellular lipid droplets induced by different hepatitis C virus genotype core sequences and relationship with steatosis
    • DOI 10.1002/hep.22288
    • Piodi A, Chouteau P, Lerat H, Hézode C, Pawlotsky JM,. Morphological changes in intracellular lipid droplets induced by different hepatitis C virus genotype core sequences and relationship with steatosis. Hepatology 2008; 48: 16-27. (Pubitemid 351975527)
    • (2008) Hepatology , vol.48 , Issue.1 , pp. 16-27
    • Piodi, A.1    Chouteau, P.2    Lerat, H.3    Hezode, C.4    Pawlotsky, J.-M.5
  • 44
    • 84859086722 scopus 로고    scopus 로고
    • Viral sequence variation in chronic carriers of hepatitis C virus has a low impact on liver steatosis
    • Depla M, d'Alteroche L, Le Gouge A, et al,. Viral sequence variation in chronic carriers of hepatitis C virus has a low impact on liver steatosis. PLoS ONE 2012; 7: e33749.
    • (2012) PLoS ONE , vol.7
    • Depla, M.1    D'Alteroche, L.2    Le Gouge, A.3
  • 45
    • 35648963197 scopus 로고    scopus 로고
    • Robust Hepatitis C Genotype 3a Cell Culture Releasing Adapted Intergenotypic 3a/2a (S52/JFH1) Viruses
    • DOI 10.1053/j.gastro.2007.08.005, PII S0016508507014515
    • Gottwein JM, Scheel TK, Hoegh AM, et al,. Robust hepatitis C genotype 3a cell culture releasing adapted intergenotypic 3a/2a (S52/JFH1) viruses. Gastroenterology 2007; 133: 1614-1626. (Pubitemid 350029736)
    • (2007) Gastroenterology , vol.133 , Issue.5 , pp. 1614-1626
    • Gottwein, J.M.1    Scheel, T.K.H.2    Hoegh, A.M.3    Lademann, J.B.4    Eugen-Olsen, J.5    Lisby, G.6    Bukh, J.7
  • 46
    • 37549005607 scopus 로고    scopus 로고
    • The lipid droplet binding domain of hepatitis C virus core protein is a major determinant for efficient virus assembly
    • Shavinskaya A, Boulant S, Penin F, McLauchlan J, Bartenschlager R,. The lipid droplet binding domain of hepatitis C virus core protein is a major determinant for efficient virus assembly. J Biol Chem 2007; 282: 37158-37169.
    • (2007) J Biol Chem , vol.282 , pp. 37158-37169
    • Shavinskaya, A.1    Boulant, S.2    Penin, F.3    McLauchlan, J.4    Bartenschlager, R.5
  • 47
    • 49149113893 scopus 로고    scopus 로고
    • Interaction of hepatitis C virus nonstructural protein 5A with core protein is critical for the production of infectious virus particles
    • Masaki T, Suzuki R, Murakami K, et al,. Interaction of hepatitis C virus nonstructural protein 5A with core protein is critical for the production of infectious virus particles. J Virol 2008; 82: 7964-7976.
    • (2008) J Virol , vol.82 , pp. 7964-7976
    • Masaki, T.1    Suzuki, R.2    Murakami, K.3
  • 48
    • 69249229453 scopus 로고    scopus 로고
    • Hepatitis C virus NS5A protein increases hepatic lipid accumulation via induction of activation and expression of PPARgamma
    • Kim K, Kim KH, Ha E, Park JY, Sakamoto N, Cheong J,. Hepatitis C virus NS5A protein increases hepatic lipid accumulation via induction of activation and expression of PPARgamma. FEBS Lett 2009; 583: 2720-2726.
    • (2009) FEBS Lett , vol.583 , pp. 2720-2726
    • Kim, K.1    Kim, K.H.2    Ha, E.3    Park, J.Y.4    Sakamoto, N.5    Cheong, J.6
  • 49
    • 70349095986 scopus 로고    scopus 로고
    • Non-structural 5A protein of hepatitis C virus induces a range of liver pathology in transgenic mice
    • Wang AG, Lee DS, Moon HB, et al,. Non-structural 5A protein of hepatitis C virus induces a range of liver pathology in transgenic mice. J Pathol 2009; 219: 253-262.
    • (2009) J Pathol , vol.219 , pp. 253-262
    • Wang, A.G.1    Lee, D.S.2    Moon, H.B.3
  • 50
    • 84860389137 scopus 로고    scopus 로고
    • Viral genotype-specific role of PNPLA3, PPARG, MTTP, and IL28B in hepatitis C virus-associated steatosis
    • Cai T, Dufour J-F, Muellhaupt B, et al,. Viral genotype-specific role of PNPLA3, PPARG, MTTP, and IL28B in hepatitis C virus-associated steatosis. J Hepatol 2011; 55: 529-535.
    • (2011) J Hepatol , vol.55 , pp. 529-535
    • Cai, T.1    Dufour, J.-F.2    Muellhaupt, B.3
  • 51
    • 69249111667 scopus 로고    scopus 로고
    • A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity
    • Sookoian S, Castaño GO, Burgueño AL, Gianotti TF, Rosselli MS, Pirola CJ,. A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity. J Lipid Res 2009; 50: 2111-2116.
    • (2009) J Lipid Res , vol.50 , pp. 2111-2116
    • Sookoian, S.1    Castaño, G.O.2    Burgueño, A.L.3    Gianotti, T.F.4    Rosselli, M.S.5    Pirola, C.J.6
  • 52
    • 79957462315 scopus 로고    scopus 로고
    • Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease
    • Sookoian S, Pirola CJ,. Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease. Hepatology 2011; 53: 1883-1894.
    • (2011) Hepatology , vol.53 , pp. 1883-1894
    • Sookoian, S.1    Pirola, C.J.2
  • 53
    • 62749100684 scopus 로고    scopus 로고
    • Microsomal triglyceride transfer protein polymorphism (-493G/T) is associated with hepatic steatosis in patients with chronic hepatitis C
    • Mirandola S, Osterreicher CH, Marcolongo M, et al,. Microsomal triglyceride transfer protein polymorphism (-493G/T) is associated with hepatic steatosis in patients with chronic hepatitis C. Liver Int 2009; 29: 557-565.
    • (2009) Liver Int , vol.29 , pp. 557-565
    • Mirandola, S.1    Osterreicher, C.H.2    Marcolongo, M.3
  • 54
    • 52149104233 scopus 로고    scopus 로고
    • Microsomal triglyceride transfer protein (MTP) -493G/T gene polymorphism contributes to fat liver accumulation in HCV genotype 3 infected patients
    • Zampino R, Ingrosso D, Durante-Mangoni E, et al,. Microsomal triglyceride transfer protein (MTP) -493G/T gene polymorphism contributes to fat liver accumulation in HCV genotype 3 infected patients. J Viral Hepat 2008; 15: 740-746.
    • (2008) J Viral Hepat , vol.15 , pp. 740-746
    • Zampino, R.1    Ingrosso, D.2    Durante-Mangoni, E.3
  • 55
    • 81355147465 scopus 로고    scopus 로고
    • Beneficial IL28B genotype associated with lower frequency of hepatic steatosis in patients with chronic hepatitis C
    • Tillmann HL, Patel K, Muir AJ, et al,. Beneficial IL28B genotype associated with lower frequency of hepatic steatosis in patients with chronic hepatitis C. J Hepatol 2011; 55: 1195-1200.
    • (2011) J Hepatol , vol.55 , pp. 1195-1200
    • Tillmann, H.L.1    Patel, K.2    Muir, A.J.3
  • 56
    • 84866409701 scopus 로고    scopus 로고
    • The association of genetic variants with hepatic steatosis in patients with genotype 1 chronic hepatitis C infection
    • Epub ahead of print
    • Clark PJ, Thompson AJ, Zhu Q, et al,. The association of genetic variants with hepatic steatosis in patients with genotype 1 chronic hepatitis C infection. Dig Dis Sci 2012; Epub ahead of print
    • (2012) Dig Dis Sci
    • Clark, P.J.1    Thompson, A.J.2    Zhu, Q.3
  • 57
    • 0029026169 scopus 로고
    • Relationship between hepatitis C virus genotypes and sources of infection in patients with chronic hepatitis C
    • Pawlotsky JM, Tsakiris L, Roudot-Thoraval F, et al,. Relationship between hepatitis C virus genotypes and sources of infection in patients with chronic hepatitis C. J Infect Dis 1995; 171: 1607-1610.
    • (1995) J Infect Dis , vol.171 , pp. 1607-1610
    • Pawlotsky, J.M.1    Tsakiris, L.2    Roudot-Thoraval, F.3
  • 58
    • 0026554450 scopus 로고
    • Hepatitis C viremia and anti-HCV antibodies in alcoholics
    • Nalpas B, Thiers V, Pol S, et al,. Hepatitis C viremia and anti-HCV antibodies in alcoholics. J Hepatol 1992; 14: 381-384.
    • (1992) J Hepatol , vol.14 , pp. 381-384
    • Nalpas, B.1    Thiers, V.2    Pol, S.3
  • 59
    • 0027179820 scopus 로고
    • Intravenous drug abuse - The major route of hepatitis C virus transmission among alcohol-dependent individuals?
    • Verbaan H, Andersson K, Eriksson S,. Intravenous drug abuse-the major route of hepatitis C virus transmission among alcohol-dependent individuals? Scand J Gastroenterol 1993; 28: 714-718. (Pubitemid 23231994)
    • (1993) Scandinavian Journal of Gastroenterology , vol.28 , Issue.8 , pp. 714-718
    • Verbaan, H.1    Andersson, K.2    Eriksson, S.3
  • 60
    • 11144342818 scopus 로고    scopus 로고
    • Hepatitis C virus core protein, cytochrome P450 2E1, and alcohol produce combined mitochondrial injury and cytotoxicity in hepatoma cells
    • DOI 10.1053/j.gastro.2004.10.045, PII S001650850401995X
    • Otani K, Korenaga M, Beard MR, et al,. Hepatitis C virus core protein, cytochrome P450 2E1, and alcohol produce combined mitochondrial injury and cytotoxicity in hepatoma cells. Gastroenterology 2005; 128: 96-107. (Pubitemid 40039962)
    • (2005) Gastroenterology , vol.128 , Issue.1 , pp. 96-107
    • Otani, K.1    Korenaga, M.2    Beard, M.R.3    Li, K.4    Qian, T.5    Showalter, L.A.6    Singh, A.K.7    Wang, T.8    Weinman, S.A.9
  • 61
    • 29244484291 scopus 로고    scopus 로고
    • Steatosis in chronic hepatitis C: Why does it really matter?
    • DOI 10.1136/gut.2005.069757
    • Asselah T, Rubbia-Brandt L, Marcellin P, Negro F,. Steatosis in chronic hepatitis C: why does it really matter? Gut 2006; 55: 123-130. (Pubitemid 41820647)
    • (2006) Gut , vol.55 , Issue.1 , pp. 123-130
    • Asselah, T.1    Rubbia-Brandt, L.2    Marcellin, P.3    Negro, F.4
  • 62
    • 33646529840 scopus 로고    scopus 로고
    • Relationship between steatosis, inflammation, and fibrosis in chronic hepatitis C: A meta-analysis of individual patient data
    • Leandro G, Mangia A, Hui J, Fabris P, et al,. Relationship between steatosis, inflammation, and fibrosis in chronic hepatitis C: a meta-analysis of individual patient data. Gastroenterology 2006; 130: 1636-1642.
    • (2006) Gastroenterology , vol.130 , pp. 1636-1642
    • Leandro, G.1    Mangia, A.2    Hui, J.3    Fabris, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.