SFRP5 inhibits gastric epithelial cell migration induced by macrophage-derived Wnt5a

Carcinogenesis

Volumn 34, Issue 1, 2013, Pages 146-152

  Zhao, Chenghai ^a   Ma, Haiying ^a   Bu, Xianmin ^a   Wang, Wei ^a   Zhang, Ning ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BACTERIUM LIPOPOLYSACCHARIDE; CHEMOKINE RECEPTOR CXCR4; PROTEIN C JUN; RECOMBINANT PROTEIN; SECRETED FRIZZLED RELATED PROTEIN 5; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; WNT5A PROTEIN;

ARTICLE; CANCER GROWTH; CELL MIGRATION; CULTURE MEDIUM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; GENE EXPRESSION; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN METHYLATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; STOMACH CANCER; STOMACH EPITHELIUM;

CELL LINE, TUMOR; DNA METHYLATION; EPITHELIAL CELLS; EYE PROTEINS; HUMANS; MACROPHAGES; MEMBRANE PROTEINS; PROTO-ONCOGENE PROTEINS; RNA, SMALL INTERFERING; STOMACH NEOPLASMS; WNT PROTEINS;

EID: 84872129603     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgs309     Document Type: Article

References (40)

1. Zhao,C. et al. (2009) Downregulation of SFRP5 expression and its inverse correlation with those of MMP-7 and MT1-MMP in gastric cancer. BMC Cancer, 9, 224.
2. Lee,A.Y. et al. (2004) Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma. Oncogene, 23, 6672-6676.
3. Urakami,S. et al. (2006) Combination analysis of hypermethylated Wntantagonist family genes as a novel epigenetic biomarker panel for bladder cancer detection. Clin. Cancer Res., 12(7 Pt 1), 2109-2116.
4. Suzuki,H. et al. (2008) Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer. Br. J. Cancer, 98, 1147-1156.
5. Götze,S. et al. (2010) Frequent promoter hypermethylation of Wnt pathway inhibitor genes in malignant astrocytic gliomas. Int. J. Cancer, 126, 2584-2593.
6. Bu,X.M. et al. (2008) Hypermethylation and aberrant expression of secreted frizzled-related protein genes in pancreatic cancer. World J. Gastroenterol., 14, 3421-3424.
7. Liang,H. et al. (2003) Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue. Cancer Cell, 4, 349-360.
8. Kremenevskaja,N. et al. (2005) Wnt-5a has tumor suppressor activity in thyroid carcinoma. Oncogene, 24, 2144-2154.
9. Kurayoshi,M. et al. (2006) Expression of Wnt-5a is correlated with aggressiveness of gastric cancer by stimulating cell migration and invasion. Cancer Res., 66, 10439-10448.
10. Weeraratna,A.T. et al. (2002) Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma. Cancer Cell, 1, 279-288.
11. Enomoto,M. et al. (2009) Autonomous regulation of osteosarcoma cell invasiveness by Wnt5a/Ror2 signaling. Oncogene, 28, 3197-3208.
12. Ripka,S. et al. (2007) WNT5A-target of CUTL1 and potent modulator of tumor cell migration and invasion in pancreatic cancer. Carcinogenesis, 28, 1178-1187.
13. Yamamoto,H. et al. (2010) Wnt5a signaling is involved in the aggressiveness of prostate cancer and expression of metalloproteinase. Oncogene, 29, 2036-2046.
14. Pukrop,T. et al. (2006) Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines. Proc. Natl. Acad. Sci. U.S.A., 103, 5454-5459.
15. Smith,K. et al. (1999) Up-regulation of macrophage wnt gene expression in adenoma-carcinoma progression of human colorectal cancer. Br. J. Cancer, 81, 496-502.
16. Schumacher,M.A. et al. (2012) Gastric Sonic Hedgehog acts as a macrophage chemoattractant during the immune response to Helicobacter pylori. Gastroenterology, 142, 1150-1159.e6.
17. Oshima,H. et al. (2011) Prostaglandin E2 signaling and bacterial infection recruit tumor-promoting macrophages to mouse gastric tumors. Gastroenterology, 140, 596-607.e7.
18. Blumenthal,A. et al. (2006) The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation. Blood, 108, 965-973.
19. Pereira,C. et al. (2008) Wnt5A/CaMKII signaling contributes to the inflammatory response of macrophages and is a target for the antiinflammatory action of activated protein C and interleukin-10. Arterioscler. Thromb. Vasc. Biol., 28, 504-510.
20. Zhao,C. et al. (2010) Involvement of tumor necrosis factor-alpha in the upregulation of CXCR4 expression in gastric cancer induced by Helicobacter pylori. BMC Cancer, 10, 419.
21. Matsuo,T. et al. (2012) Gastric cancer development after Helicobacter pylori eradication therapy: a new form of gastric neoplasia. Digestion, 85, 61-67.
22. Katoh,M. et al. (2009) Transcriptional mechanisms of WNT5A based on NF-kappaB, Hedgehog, TGFbeta, and Notch signaling cascades. Int. J. Mol. Med., 23, 763-769.
23. Sen,M. et al. (2000) Expression and function of wingless and frizzled homologs in rheumatoid arthritis. Proc. Natl. Acad. Sci. U.S.A., 97, 2791-2796.
24. Li,B. et al. (2011) WNT5A signaling contributes to Aβ-induced neuroinflammation and neurotoxicity. PLoS ONE, 6, e22920.
25. O'Connell,M.P. et al. (2010) The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma. Oncogene, 29, 34-44.
26. Wang,Q. et al. (2010) A novel role for Wnt/Ca2+ signaling in actin cytoskeleton remodeling and cell motility in prostate cancer. PLoS ONE, 5, e10456.
27. Kim,J. et al. (2010) Wnt5a induces endothelial inflammation via betacatenin-independent signaling. J. Immunol., 185, 1274-1282.
28. Ouchi,N. et al. (2010) Sfrp5 is an anti-inflammatory adipokine that modulates metabolic dysfunction in obesity. Science, 329, 454-457.
29. Tamura,M. et al. (2011) Regulation of CXCL12 expression by canonical Wnt signaling in bone marrow stromal cells. Int. J. Biochem. Cell Biol., 43, 760-767.
30. Aman,A. et al. (2008) Wnt/beta-catenin and Fgf signaling control collective cell migration by restricting chemokine receptor expression. Dev. Cell, 15, 749-761.
31. Ghosh,M.C. et al. (2009) Activation of Wnt5A signaling is required for CXC chemokine ligand 12-mediated T-cell migration. Blood, 114, 1366-1373.
32. Kang,G.H. et al. (2008) DNA methylation profiles of gastric carcinoma characterized by quantitative DNA methylation analysis. Lab. Invest., 88, 161-170.
33. Su,H.Y. et al. (2010) Epigenetic silencing of SFRP5 is related to malignant phenotype and chemoresistance of ovarian cancer through Wnt signaling pathway. Int. J. Cancer, 127, 555-567.
34. Veeck,J. et al. (2008) Epigenetic inactivation of the secreted frizzledrelated protein-5 (SFRP5) gene in human breast cancer is associated with unfavorable prognosis. Carcinogenesis, 29, 991-998.
35. Li,Y. et al. (2008) Sfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling. Genes Dev., 22, 3050-3063.
36. Oliveira,M.J. et al. (2006) Helicobacter pylori induces gastric epithelial cell invasion in a c-Met and type IV secretion system-dependent manner. J. Biol. Chem., 281, 34888-34896.
37. Nagy,T.A. et al. (2009) Helicobacter pylori regulates cellular migration and apoptosis by activation of phosphatidylinositol 3-kinase signaling. J. Infect. Dis., 199, 641-651.
38. Kitadai,Y. et al. (2003) Helicobacter pylori infection influences expression of genes related to angiogenesis and invasion in human gastric carcinoma cells. Biochem. Biophys. Res. Commun., 311, 809-814.
39. Pollard,J.W. (2004) Tumour-educated macrophages promote tumour progression and metastasis. Nat. Rev. Cancer, 4, 71-78.
40. Mantovani,A. et al. (2006) Role of tumor-associated macrophages in tumor progression and invasion. Cancer Metastasis Rev., 25, 315-322.