Synthesis, biochemical evaluation and molecular modeling studies of novel rhodium complexes with nanomolar activity against platelet activating factor

Journal of Inorganic Biochemistry

Volumn 120, Issue , 2013, Pages 63-73

  Tsoupras, Alexandros B ^a   Papakyriakou, Athanasios ^b   Demopoulos, Constantinos A ^a   Philippopoulos, Athanassios I ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

Author keywords

Cancer; Inflammation; PAF inhibition; PAFreceptor; Platelet Activating Factor (PAF); Rhodium complexes

Indexed keywords

RHODIUM COMPLEX; THROMBOCYTE ACTIVATING FACTOR; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST;

ARTICLE; DRUG INHIBITION; DRUG SCREENING; DRUG SYNTHESIS; IC 50; LIGAND BINDING; MOLECULAR DOCKING; MOLECULAR MODEL;

ANIMALS; AZEPINES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; INHIBITORY CONCENTRATION 50; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; ORGANOMETALLIC COMPOUNDS; PLATELET ACTIVATING FACTOR; PLATELET AGGREGATION INHIBITORS; RABBITS; RHODIUM; STRUCTURE-ACTIVITY RELATIONSHIP; THROMBIN; TRIAZOLES;

EID: 84872129041     PISSN: 01620134     EISSN: 18733344     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2012.12.004     Document Type: Article

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