Exploring key orientations at protein-protein interfaces with small molecule probes

Journal of the American Chemical Society

Volumn 135, Issue 1, 2013, Pages 167-173

  Ko, Eunhwa ^a   Raghuraman, Arjun ^a   Perez, Lisa M ^a   Ioerger, Thomas R ^a   Burgess, Kevin ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMEDICAL SCIENCE; CHEMOTYPES; DATA MINING ALGORITHM; HIV-1 PROTEASE; INTERFACE REGIONS; PROTEIN-PROTEIN INTERACTIONS; PROTEIN-PROTEIN INTERFACE; SIDE-CHAINS; SMALL MOLECULES;

ALGORITHMS; AMINO ACIDS; DATA MINING; DIMERIZATION; MOLECULES; PROBES; PROTEINS;

CONFORMATIONS;

AMINO ACID; HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE; MOLECULAR SCAFFOLD;

ALGORITHM; AMINO ACID SEQUENCE; ARTICLE; BIOMEDICINE; CONTROLLED STUDY; DATA MINING; DIMERIZATION; MOLECULAR PROBE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RIGIDITY;

ALGORITHMS; DIMERIZATION; FLUORESCENT DYES; HIV PROTEASE; MODELS, MOLECULAR; PROTEIN BINDING; SMALL MOLECULE LIBRARIES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84872118404     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja3067258     Document Type: Article

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