Triterpenes as potential dimerization inhibitors of HIV-1 protease

Biochemical and Biophysical Research Communications

Volumn 227, Issue 2, 1996, Pages 484-488

  Quéré, Luc ^a   Wenger, Traudl ^a   Schramm, Hans J ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE INHIBITOR; TRITERPENE;

AMINO ACID SEQUENCE; ARTICLE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROGEN BOND; PRIORITY JOURNAL; VIRUS INHIBITION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0030583586     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.1996.1533     Document Type: Article

References (18)

1. 1. Schramm, H. J., Nakashima, H., Schramm, W., Wakayama, H., and Yamamoto, N. (1991) Biochem. Biophys. Res. Comm. 179, 847-851.
2. 2. Zhang, Z.-Y., Poorman, R. A., Maggiora, L. L., Heinrikson, R. L., and Kezdy, F. J. (1991) J. Biol. Chem. 266, 15591-15594.
3. 3. Schramm, H. J., Boetzel, J., Büttner, J., Fritsche, E., Göhring, W., Jaeger, E., König, S., Thumfart, O., Wenger, T., Nagel, N. E., and Schramm, W. (1996) Antiviral Res. 30, 155-170.
4. 4. Wlodawer, A., and Erickson, J. (1993) Ann. Rev. Biochem. 62, 543-585.
5. 5. Billich, A., Hammerschmidt, F., and Winkler, G. (1990) Biol. Chem. Hoppe-Seyler 371, 265-271.
6. 6. Richards, A. D., Phylip, L. H., Farmerie, W. G., Scarborough, P. E., Alvarez, A., Dunn, B. M., Hirel, P.-H., Konvalinka, J., Strop, P., Pavlickova, L., Kostka, V., and Kay, J. (1990) J. Biol. Chem. 265, 7733-7736.
7. 7. Wang, S., Milne, G. W. A., Yan, X., Posey, I. J., Nicklaus, M. C., Graham, L., and Rice, W. G. (1996) J. Med. Chem. 39, 2047-2054.
8. 8. Kennard, O., Watson, D. G., Allen, F. H., Motherwell, W. D. S., Town, W. G., and Rodgers, J. (1975) Chem. Ber. 11, 213-216.
9. 9. Allen, F. M., and Kennard, O. (1993) Chem. Design and Automat. News 8, 31-37.
10. 10. CSD System Design, Programming and Documentation (October 1992).
11. 11. Erickson, J., Neidhart, D. J., Van Drie, J., Kempf, D. J., Wang, X. C., Norbeck, D. W., Plattner, J. J., Rittenhouse, J. W., Turon, M., Widebrug, N., Kohlbrenner, W. E., Simmer, R., Helfrick, R., Paul, D. A., and Knigge, M. (1990) Science 249, 527-532.
12. 12. Venable, R. M., Brooks, B. R., and Carson, F. W. (1993) Proteins: Struct., Funct. and Genet. 15, 374-384.
13. 13. Hirschmann, R., Sprengler, P. A., Kawasaki, T., Leaky, J. W., Shakespeare, W. C., and Smith, A. B., III (1992) J. Am. Chem. Soc. 114, 9699-9701.
14. 14. Okano, M., Fukamiya, N., Tagahara, K., Cosentino, M., Lee, M. T.-Y., Morris-Natschke, S., and Lee, K.-H. (1996) Bioorg. & Med. Chem. Lett. 6, 701-706.
15. 15. Evers, M., Poujade, C., Soler, F., Ribeill, Y., Lelièvre, Y., Gueguen, J.-C., Reisdorf, D., Morize, I., Pauwels, R., De Clercq, E., Hénin, Y., Bousseau, A., Mayaux, J.-F., Le Pecq, J.-B., and Dereu, N. (1996) J. Med. Chem. 39, 1056-1068.
16. 16. Ying, Q.-L., Rinehart, A. R., Simon, S. R., and Cheronis, J. C. (1991) Biochem. J. 277, 521-526.
17. 17. Karrer, W. (1976) Konstitution und Vorkommen der organischen Pflanzenstoffe, Birkhäuser Verlag, Basel und Stuttgart.
18. 18. Devon, T. K., and Scott, A. I. (1975) Handbook of Naturally Occurring Compounds, Vol. II, Academic Press, New York/San Francisco/London.