Activation of p38 MAPK through transient receptor potential A1 in a rat model of gastric distension-induced visceral pain

NeuroReport

Volumn 24, Issue 2, 2013, Pages 68-72

  Kondo, Takashi ^a   Sakurai, Jun ^a   Miwa, Hiroto ^a   Noguchi, Koichi ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

Dorsal root ganglion; Gastric distension; P38 MAPK; Transient receptor potential A1; Visceral pain

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ELECTROMYOGRAPHY; ENZYME ACTIVATION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INFLAMMATION; MALE; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL GANGLION; STOMACH DISTENSION; VISCERAL PAIN;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; GANGLIA, SPINAL; HYPERALGESIA; IMIDAZOLES; MALE; NEURONS, AFFERENT; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TRPC CATION CHANNELS; VISCERAL PAIN;

EID: 84872095211     PISSN: 09594965     EISSN: 1473558X     Source Type: Journal    
DOI: 10.1097/WNR.0b013e32835c7df2     Document Type: Article

References (23)

1. Ozaki N, Gebhart GF. Characterization of mechanosensitive splanchnic nerve afferent fibers innervating the rat stomach. Am J Physiol Gastrointest Liver Physiol 2001; 281:G1449-G1459.
2. Ozaki N, Bielefeldt K, Sengupta JN, Gebhart GF. Models of gastric hyperalgesia in the rat. Am J Physiol Gastrointest Liver Physiol 2002; 283:G666-G676. (Pubitemid 34920355)
3. Lamb K, Kang YM, Gebhart GF, Bielefeldt K. Gastric inflammation triggers hypersensitivity to acid in awake rats. Gastroenterology 2003; 125:1410-1418. (Pubitemid 37409761)
4. Kondo T, Obata K, Miyoshi K, Sakurai J, Tanaka J, Miwa H, et al. Transient receptor potential A1 mediates gastric distension-induced visceral pain in rats. Gut 2009; 58:1342-1352.
5. Sakurai J, Obata K, Ozaki N, Tokunaga A, Kobayashi K, Yamanaka H, et al. Activation of extracellular signal-regulated protein kinase in sensory neurons after noxious gastric distension and its involvement in acute visceral pain in rats. Gastroenterology 2008; 134:1094-1103. (Pubitemid 351451978)
6. Kondo T, Oshima T, Obata K, Sakurai J, Knowles CH, Matsumoto T, et al. Role of transient receptor potential A1 in gastric nociception. Digestion 2010; 82:150-155.
7. Lewis TS, Shapiro PS, Ahn NG. Signal transduction through MAP kinase cascades. Adv Cancer Res 1998; 74:49-139. (Pubitemid 28193546)
8. Widmann C, Gibson S, Jarpe MB, Johnson GL. Mitogen-activated protein kinase:conservation of a three-kinase module from yeast to human. Physiol Rev 1999; 79:143-180. (Pubitemid 29056951)
9. Shi Y, Gaestel M. In the cellular garden of forking paths:how p38 MAPKs signal for downstream assistance. Biol Chem 2002; 383:1519-1536. (Pubitemid 35282972)
10. Ji RR, Samad TA, Jin SX, Schmoll R, Woolf CJ. p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia. Neuron 2002; 36:57-68.
11. Jin SX, Zhuang ZY,Woolf CJ, Ji RR. p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain. J Neurosci 2003; 23:4017-4022. (Pubitemid 36958419)
12. Kim SY, Bae JC, Kim JY, Lee HL, Lee KM, Kim DS, et al. Activation of p38 MAP kinase in the rat dorsal root ganglia and spinal cord following peripheral inflammation and nerve injury. Neuroreport 2002; 13:2483-2486.
13. Obata K, Noguchi K. MAPK activation in nociceptive neurons and pain hypersensitivity. Life Sci 2004; 74:2643-2653. (Pubitemid 38369361)
14. Schafers M, Svensson CI, Sommer C, Sorkin LS. Tumor necrosis factoralpha induces mechanical allodynia after spinal nerve ligation by activation of p38 MAPK in primary sensory neurons. J Neurosci 2003; 23:2517-2521. (Pubitemid 36418584)
15. Mizushima T, Obata K, Yamanaka H, Dai Y, Fukuoka T, Tokunaga A, et al. Activation of p38 MAPK in primary afferent neurons by noxious stimulation and its involvement in the development of thermal hyperalgesia. Pain 2005; 113:51-60. (Pubitemid 40038446)
16. Fukuoka T, Kondo E, Dai Y, Hashimoto N, Noguchi K. Brain-derived neurotrophic factor increases in the uninjured dorsal root ganglion neurons in selective spinal nerve ligation model. J Neurosci 2001; 21:4891-4900. (Pubitemid 32565647)
17. Noguchi K, Kawai Y, Fukuoka T, Senba E, Miki K. Substance P induced by peripheral nerve injury in primary afferent sensory neurons and its effect on dorsal column nucleus neurons. J Neurosci 1995; 15:7633-7643.
18. Michael GJ, Averill S, Nitkunan A, Rattray M, Bennett DL, Yan Q, et al. Nerve growth factor treatment increases brain-derived neurotrophic factor selectively in TrkA-expressing dorsal root ganglion cells and in their central terminations within the spinal cord. J Neurosci 1997; 17:8476-8490. (Pubitemid 27461069)
19. Dai Y, Wang S, Tominaga M, Yamamoto S, Fukuoka T, Higashi T, et al. Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain. J Clin Invest 2007; 117:1979-1987. (Pubitemid 47036332)
20. Obata K, Katsura H, Mizushima T, Yamanaka H, Kobayashi K, Dai Y, et al. TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury. J Clin Invest 2005; 115:2393-2401. (Pubitemid 41266201)
21. Dai Y, Iwata K, Fukuoka T, Kondo E, Tokunaga A, Yamanaka H, et al. Phosphorylation of extracellular signal-regulated kinase in primary afferent neurons by noxious stimuli and its involvement in peripheral sensitization. J Neurosci 2002; 22:7737-7745. (Pubitemid 35386372)
22. Bradesi S, Svensson CI, Steinauer J, Pothoulakis C, Yaksh TL, Mayer EA. Role of spinal microglia in visceral hyperalgesia and NK1R up-regulation in a rat model of chronic stress. Gastroenterology 2009; 136:1339-1348, e1331-e1332.
23. Torocsik B, Szeberenyi J. Anisomycin uses multiple mechanisms to stimulate mitogen-activated protein kinases and gene expression and to inhibit neuronal differentiation in PC12 phaeochromocytoma cells. Eur J Neurosci 2000; 12:527-532. (Pubitemid 30142753)