CXC-chemokine receptor 4 antagonist AMD3100 promotes cardiac functional recovery after ischemia/reperfusion injury via endothelial nitric oxide synthase-dependent mechanism

Circulation

Volumn 127, Issue 1, 2013, Pages 63-73

  Jujo, Kentaro ^a,b   Ii, Masaaki ^c   Sekiguchi, Haruki ^b   Klyachko, Ekaterina ^a   Misener, Sol ^a   Tanaka, Toshikazu ^a,b   Tongers, Jörn ^a   Roncalli, Jérôme ^a   Renault, Marie Ange ^a   Thorne, Tina ^a   Ito, Aiko ^a   Clarke, Trevor ^a   Kamide, Christine ^a   Tsurumi, Yukio ^d   Hagiwara, Nobuhisa ^b   Qin, Gangjian ^a   Asahi, Michio ^c   Losordo, Douglas W ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^c OSAKA MEDICAL COLLEGE   (Japan)

^d HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

ischemia; myocardium; nitric oxide synthase; pharmaceutical preparations; reperfusion

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; GELATINASE B; PLERIXAFOR;

ACUTE HEART INFARCTION; ARTICLE; BLOOD FLOW; BONE MARROW; CARDIOVASCULAR RISK; HEART FUNCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE FUNCTION; HEART PROTECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; STEM CELL MOBILIZATION; UPREGULATION;

ANIMALS; BONE MARROW TRANSPLANTATION; CARDIOTONIC AGENTS; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEMATOPOIETIC STEM CELL MOBILIZATION; HEMATOPOIETIC STEM CELLS; HETEROCYCLIC COMPOUNDS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; NITRIC OXIDE SYNTHASE TYPE III; RECEPTORS, CXCR4; RECOVERY OF FUNCTION; SIGNAL TRANSDUCTION;

EID: 84872088957     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.112.099242     Document Type: Article

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