-
1
-
-
77049113770
-
The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity
-
Brew, K., and Nagase, H. (2010) The tissue inhibitors of metalloproteinases (TIMPs): an ancient family with structural and functional diversity. Biochim. Biophys. Acta 1803, 55-71
-
(2010)
Biochim. Biophys. Acta
, vol.1803
, pp. 55-71
-
-
Brew, K.1
Nagase, H.2
-
2
-
-
0025962223
-
The 21-kDa protein is a transformation-sensitive metalloproteinase inhibitor of chicken fibroblasts
-
Staskus, P. W., Masiarz, F. R., Pallanck, L. J., and Hawkes, S. P. (1991) The 21-kDa protein is a transformation-sensitive metalloproteinase inhibitor of chicken fibroblasts. J. Biol. Chem. 266, 449-454 (Pubitemid 21906142)
-
(1991)
Journal of Biological Chemistry
, vol.266
, Issue.1
, pp. 449-454
-
-
Staskus, P.W.1
Masiarz, F.R.2
Pallanck, L.J.3
Hawkes, S.P.4
-
3
-
-
0034613296
-
TIMP-3 binds to sulfated glycosaminoglycans of the extracellular matrix
-
Yu, W. H., Yu, S., Meng, Q., Brew, K., and Woessner, J. F. (2000) TIMP-3 binds to sulfated glycosaminoglycans of the extracellular matrix. J. Biol. Chem. 275, 31226-31232
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 31226-31232
-
-
Yu, W.H.1
Yu, S.2
Meng, Q.3
Brew, K.4
Woessner, J.F.5
-
4
-
-
0034833362
-
Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3)
-
DOI 10.1172/JCI200112067
-
Leco, K. J., Waterhouse, P., Sanchez, O. H., Gowing, K. L., Poole, A. R., Wakeham, A., Mak, T. W., and Khokha, R. (2001) Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3). J. Clin. Invest. 108, 817-829 (Pubitemid 32884192)
-
(2001)
Journal of Clinical Investigation
, vol.108
, Issue.6
, pp. 817-829
-
-
Leco, K.J.1
Waterhouse, P.2
Sanchez, O.H.3
Gowing, K.L.M.4
Poole, A.R.5
Wakeham, A.6
Mak, T.W.7
Khokha, R.8
-
5
-
-
6444240024
-
TIMP-3 deficiency leads to dilated cardiomyopathy
-
DOI 10.1161/01.CIR.0000134959.83967.2D
-
Fedak, P. W., Smookler, D. S., Kassiri, Z., Ohno, N., Leco, K. J., Verma, S., Mickle, D. A., Watson, K. L., Hojilla, C. V., Cruz, W., Weisel, R. D., Li, R. K., and Khokha, R. (2004) TIMP-3 deficiency leads to dilated cardiomyopathy. Circulation 110, 2401-2409 (Pubitemid 39407346)
-
(2004)
Circulation
, vol.110
, Issue.16
, pp. 2401-2409
-
-
Fedak, P.W.M.1
Smookler, D.S.2
Kassiri, Z.3
Ohno, N.4
Leco, K.J.5
Verma, S.6
Mickle, D.A.G.7
Watson, K.L.8
Hojilla, C.V.9
Cruz, W.10
Weisel, R.D.11
Li, R.-K.12
Khokha, R.13
-
6
-
-
0034823461
-
Accelerated apoptosis in the Timp-3-deficient mammary gland
-
DOI 10.1172/JCI200113171
-
Fata, J. E., Leco, K. J., Voura, E. B., Yu, H. Y., Waterhouse, P., Murphy, G., Moorehead, R. A., and Khokha, R. (2001) Accelerated apoptosis in the TIMP-3-deficient mammary gland. J. Clin. Invest. 108, 831-841 (Pubitemid 32880292)
-
(2001)
Journal of Clinical Investigation
, vol.108
, Issue.6
, pp. 831-841
-
-
Fata, J.E.1
Leco, K.J.2
Voura, E.B.3
Yu, H.-Y.E.4
Waterhouse, P.5
Murphy, G.6
Moorehead, R.A.7
Khokha, R.8
-
7
-
-
33947175117
-
-/- mice
-
DOI 10.1002/art.22427
-
Sahebjam, S., Khokha, R., and Mort, J. S. (2007) Increased collagen and aggrecan degradation with age in the joints of Timp3-/- mice. Arthritis Rheum. 56, 905-909 (Pubitemid 46399438)
-
(2007)
Arthritis and Rheumatism
, vol.56
, Issue.3
, pp. 905-909
-
-
Sahebjam, S.1
Khokha, R.2
Mort, J.S.3
-
8
-
-
4444229437
-
-/- mice leads to chronic hepatic inflammation and failure of liver regeneration
-
-/- mice leads to chronic hepatic inflammation and failure of liver regeneration. Nat. Genet. 36, 969-977
-
(2004)
Nat. Genet.
, vol.36
, pp. 969-977
-
-
Mohammed, F.F.1
Smookler, D.S.2
Taylor, S.E.3
Fingleton, B.4
Kassiri, Z.5
Sanchez, O.H.6
English, J.L.7
Matrisian, L.M.8
Au, B.9
Yeh, W.C.10
Khokha, R.11
-
9
-
-
0345358579
-
Negative impact of tissue inhibitor of metalloproteinase-3 null mutation on lung structure and function in response to sepsis
-
Martin, E. L., Moyer, B. Z., Pape, M. C., Starcher, B., Leco, K. J., and Veldhuizen, R. A. (2003) Negative impact of tissue inhibitor of metalloproteinase-3 null mutation on lung structure and function in response to sepsis. Am. J. Physiol. Lung Cell Mol. Physiol. 285, L1222-1232 (Pubitemid 37448793)
-
(2003)
American Journal of Physiology - Lung Cellular and Molecular Physiology
, vol.285
, Issue.6
-
-
Martin, E.L.1
Moyer, B.Z.2
Pape, M.C.3
Starcher, B.4
Leco, K.J.5
Veldhuizen, R.A.W.6
-
10
-
-
70349633646
-
TIMP3 is reduced in atherosclerotic plaques from subjects with type 2 diabetes and increased by SirT1
-
Cardellini, M., Menghini, R., Martelli, E., Casagrande, V., Marino, A., Rizza, S., Porzio, O., Mauriello, A., Solini, A., Ippoliti, A., Lauro, R., Folli, F., and Federici, M. (2009) TIMP3 is reduced in atherosclerotic plaques from subjects with type 2 diabetes and increased by SirT1. Diabetes 58, 2396-2401
-
(2009)
Diabetes
, vol.58
, pp. 2396-2401
-
-
Cardellini, M.1
Menghini, R.2
Martelli, E.3
Casagrande, V.4
Marino, A.5
Rizza, S.6
Porzio, O.7
Mauriello, A.8
Solini, A.9
Ippoliti, A.10
Lauro, R.11
Folli, F.12
Federici, M.13
-
11
-
-
0032531277
-
Up-regulation of tissue inhibitor of metalloproteinases-3 gene expression by TGF-β in articular chondrocytes is mediated by serine/threonine and tyrosine kinases
-
DOI 10.1002/(SICI)1097-4644(19980915)70:4<517::AID-JCB8>3.0.CO;2-M
-
Su, S., DiBattista, J. A., Sun, Y., Li, W. Q., and Zafarullah, M. (1998) Upregulation of tissue inhibitor of metalloproteinases-3 gene expression by TGF-β in articular chondrocytes is mediated by serine/threonine and tyrosine kinases. J. Cell Biochem. 70, 517-527 (Pubitemid 28357961)
-
(1998)
Journal of Cellular Biochemistry
, vol.70
, Issue.4
, pp. 517-527
-
-
Su, S.1
DiBattista, J.A.2
Sun, Y.3
Li, W.Q.4
Zafarullah, M.5
-
12
-
-
0001155860
-
Oncostatin M up-regulates tissue inhibitor of metalloproteinases-3 gene expression in articular chondrocytes viade novo transcription, protein synthesis, and tyrosine kinase- and mitogen-activated protein kinase- dependent mechanisms
-
Li, W. Q., and Zafarullah, M. (1998) Oncostatin M up-regulates tissue inhibitor of metalloproteinases-3 gene expression in articular chondrocytes via de novo transcription, protein synthesis, and tyrosine kinase- and mitogen-activated protein kinase-dependent mechanisms. J. Immunol. 161, 5000-5007 (Pubitemid 28492082)
-
(1998)
Journal of Immunology
, vol.161
, Issue.9
, pp. 5000-5007
-
-
Li, W.Q.1
Zafarullah, M.2
-
13
-
-
18644384743
-
Tissue inhibitor of metalloproteinase-3 (TIMP-3) gene is methylated in the development of esophageal adenocarcinoma: Loss of expression correlates with poor prognosis
-
DOI 10.1002/ijc.20830
-
Darnton, S. J., Hardie, L. J., Muc, R. S., Wild, C. P., and Casson, A. G. (2005) Tissue inhibitor of metalloproteinase-3 (TIMP-3) gene is methylated in the development of esophageal adenocarcinoma: loss of expression correlates with poor prognosis. Int. J. Cancer 115, 351-358 (Pubitemid 40663737)
-
(2005)
International Journal of Cancer
, vol.115
, Issue.3
, pp. 351-358
-
-
Darnton, S.J.1
Hardie, L.J.2
Muc, R.S.3
Wild, C.P.4
Casson, A.G.5
-
14
-
-
50249173450
-
MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators
-
Gabriely, G., Wurdinger, T., Kesari, S., Esau, C. C., Burchard, J., Linsley, P. S., and Krichevsky, A. M. (2008) MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. Mol. Cell. Biol. 28, 5369-5380
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 5369-5380
-
-
Gabriely, G.1
Wurdinger, T.2
Kesari, S.3
Esau, C.C.4
Burchard, J.5
Linsley, P.S.6
Krichevsky, A.M.7
-
15
-
-
70949104622
-
miR- 221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation
-
Garofalo, M., Di Leva, G., Romano, G., Nuovo, G., Suh, S. S., Ngankeu, A., Taccioli, C., Pichiorri, F., Alder, H., Secchiero, P., Gasparini, P., Gonelli, A., Costinean, S., Acunzo, M., Condorelli, G., and Croce, C. M. (2009) miR- 221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation. Cancer Cell 16, 498-509
-
(2009)
Cancer Cell
, vol.16
, pp. 498-509
-
-
Garofalo, M.1
Di Leva, G.2
Romano, G.3
Nuovo, G.4
Suh, S.S.5
Ngankeu, A.6
Taccioli, C.7
Pichiorri, F.8
Alder, H.9
Secchiero, P.10
Gasparini, P.11
Gonelli, A.12
Costinean, S.13
Acunzo, M.14
Condorelli, G.15
Croce, C.M.16
-
16
-
-
77950095763
-
TGFβ-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3
-
Wang, B., Hsu, S. H., Majumder, S., Kutay, H., Huang, W., Jacob, S. T., and Ghoshal, K. (2010) TGFβ-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3. Oncogene 29, 1787-1797
-
(2010)
Oncogene
, vol.29
, pp. 1787-1797
-
-
Wang, B.1
Hsu, S.H.2
Majumder, S.3
Kutay, H.4
Huang, W.5
Jacob, S.T.6
Ghoshal, K.7
-
17
-
-
79959464268
-
HMGB1 attenuates cardiac remodelling in the failing heart via enhanced cardiac regeneration and miR-206-mediated inhibition of TIMP-3
-
Limana, F., Esposito, G., D'Arcangelo, D., Di Carlo, A., Romani, S., Melillo, G., Mangoni, A., Bertolami, C., Pompilio, G., Germani, A., and Capogrossi, M. C. (2011) HMGB1 attenuates cardiac remodelling in the failing heart via enhanced cardiac regeneration and miR-206-mediated inhibition of TIMP-3. PLoS One 6, e19845
-
(2011)
PLoS One
, vol.6
-
-
Limana, F.1
Esposito, G.2
D'Arcangelo, D.3
Di Carlo, A.4
Romani, S.5
Melillo, G.6
Mangoni, A.7
Bertolami, C.8
Pompilio, G.9
Germani, A.10
Capogrossi, M.C.11
-
18
-
-
54049085750
-
Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases
-
Troeberg, L., Fushimi, K., Khokha, R., Emonard, H., Ghosh, P., and Nagase, H. (2008) Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases. FASEB J. 22, 3515-3524
-
(2008)
FASEB J.
, vol.22
, pp. 3515-3524
-
-
Troeberg, L.1
Fushimi, K.2
Khokha, R.3
Emonard, H.4
Ghosh, P.5
Nagase, H.6
-
19
-
-
0036514256
-
Diverse roles for the LDL receptor family
-
DOI 10.1016/S1043-2760(01)00526-4, PII S1043276001005264
-
Strickland, D. K., Gonias, S. L., and Argraves, W. S. (2002) Diverse roles for the LDL receptor family. Trends Endocrinol. Metab. 13, 66-74 (Pubitemid 36740449)
-
(2002)
Trends in Endocrinology and Metabolism
, vol.13
, Issue.2
, pp. 66-74
-
-
Strickland, D.K.1
Gonias, S.L.2
Argraves, W.S.3
-
20
-
-
28344453429
-
Beyond endocytosis: LRP function in cell migration, proliferation and vascular permeability
-
DOI 10.1111/j.1538-7836.2005.01371.x
-
Lillis, A. P., Mikhailenko, I., and Strickland, D. K. (2005) Beyond endocytosis: LRP function in cell migration, proliferation and vascular permeability. J. Thromb. Haemost. 3, 1884-1893 (Pubitemid 41716576)
-
(2005)
Journal of Thrombosis and Haemostasis
, vol.3
, Issue.8
, pp. 1884-1893
-
-
Lillis, A.P.1
Mikhailenko, I.2
Strickland, D.K.3
-
21
-
-
80051824506
-
Shedding of low density lipoprotein receptor-related protein-1 in acute respiratory distress syndrome
-
Wygrecka, M., Wilhelm, J., Jablonska, E., Zakrzewicz, D., Preissner, K. T., Seeger, W., Guenther, A., and Markart, P. (2011) Shedding of low density lipoprotein receptor-related protein-1 in acute respiratory distress syndrome. Am. J. Respir. Crit Care Med. 184, 438-448
-
(2011)
Am. J. Respir. Crit Care Med.
, vol.184
, pp. 438-448
-
-
Wygrecka, M.1
Wilhelm, J.2
Jablonska, E.3
Zakrzewicz, D.4
Preissner, K.T.5
Seeger, W.6
Guenther, A.7
Markart, P.8
-
22
-
-
67651148199
-
Metalloproteinase-dependent shedding of low density lipoprotein receptor-related protein-1 ectodomain decreases endocytic clearance of endometrial matrix metalloproteinase-2 and -9 at menstruation
-
Selvais, C., Gaide Chevronnay, H. P., Lemoine, P., Dedieu, S., Henriet, P., Courtoy, P. J., Marbaix, E., and Emonard, H. (2009) Metalloproteinase- dependent shedding of low density lipoprotein receptor-related protein-1 ectodomain decreases endocytic clearance of endometrial matrix metalloproteinase-2 and -9 at menstruation. Endocrinology 150, 3792-3799
-
(2009)
Endocrinology
, vol.150
, pp. 3792-3799
-
-
Selvais, C.1
Gaide Chevronnay, H.P.2
Lemoine, P.3
Dedieu, S.4
Henriet, P.5
Courtoy, P.J.6
Marbaix, E.7
Emonard, H.8
-
23
-
-
65349140569
-
LRP1 shedding in human brain: Roles of ADAM10 and ADAM17
-
Liu, Q., Zhang, J., Tran, H., Verbeek, M. M., Reiss, K., Estus, S., and Bu, G. (2009) LRP1 shedding in human brain: roles of ADAM10 and ADAM17. Mol. Neurodegener. 4, 17
-
(2009)
Mol. Neurodegener.
, vol.4
, pp. 17
-
-
Liu, Q.1
Zhang, J.2
Tran, H.3
Verbeek, M.M.4
Reiss, K.5
Estus, S.6
Bu, G.7
-
25
-
-
0028800945
-
Analysis of ligand binding to the α2-macroglobulin receptor/lowdensity lipoprotein receptor-related protein: Evidence that lipoprotein lipase and the carboxyl-terminal domain of the receptor-associated protein bind to the same site
-
Nielsen, M. S., Nykjaer, A., Warshawsky, I., Schwartz, A. L., and Gliemann, J. (1995) Analysis of ligand binding to the α2-macroglobulin receptor/lowdensity lipoprotein receptor-related protein: evidence that lipoprotein lipase and the carboxyl-terminal domain of the receptor-associated protein bind to the same site. J. Biol. Chem. 270, 23713-23719
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 23713-23719
-
-
Nielsen, M.S.1
Nykjaer, A.2
Warshawsky, I.3
Schwartz, A.L.4
Gliemann, J.5
-
26
-
-
1642280932
-
Altered Proteolytic Activities of ADAMTS-4 Expressed by C-terminal Processing
-
DOI 10.1074/jbc.M312123200
-
Kashiwagi, M., Enghild, J. J., Gendron, C., Hughes, C., Caterson, B., Itoh, Y., and Nagase, H. (2004) Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing. J. Biol. Chem. 279, 10109-10119 (Pubitemid 38372615)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.11
, pp. 10109-10119
-
-
Kashiwagi, M.1
Enghild, J.J.2
Gendron, C.3
Hughes, C.4
Caterson, B.5
Itoh, Y.6
Nagase, H.7
-
27
-
-
70449722891
-
The C-terminal domains of ADAMTS-4 and ADAMTS-5 promote association with N-TIMP-3
-
Troeberg, L., Fushimi, K., Scilabra, S. D., Nakamura, H., Dive, V., Thøgersen, I. B., Enghild, J. J., and Nagase, H. (2009) The C-terminal domains of ADAMTS-4 and ADAMTS-5 promote association with N-TIMP-3. Matrix Biol. 28, 463-469
-
(2009)
Matrix Biol.
, vol.28
, pp. 463-469
-
-
Troeberg, L.1
Fushimi, K.2
Scilabra, S.D.3
Nakamura, H.4
Dive, V.5
Thøgersen, I.B.6
Enghild, J.J.7
Nagase, H.8
-
28
-
-
2142854239
-
Animal cell mutants defective in glycosaminoglycan biosynthesis
-
DOI 10.1073/pnas.82.10.3197
-
Esko, J. D., Stewart, T. E., and Taylor, W. H. (1985) Animal cell mutants defective in glycosaminoglycan biosynthesis. Proc. Natl. Acad. Sci. U.S.A. 82, 3197-3201 (Pubitemid 15029573)
-
(1985)
Proceedings of the National Academy of Sciences of the United States of America
, vol.82
, Issue.10
, pp. 3197-3201
-
-
Esko, J.D.1
Stewart, T.E.2
Taylor, W.H.3
-
29
-
-
0028343888
-
Genetic deficiency in low density lipoprotein receptor-related protein confers cellular resistance to Pseudomonas endotoxin A: Evidence that this protein is required for uptake and degradation of multiple ligands
-
Willnow, T. E., and Herz, J. (1994) Genetic deficiency in low density lipoprotein receptor-related protein confers cellular resistance to Pseudomonas endotoxin A: evidence that this protein is required for uptake and degradation of multiple ligands J. Cell Sci. 107, 719-726
-
(1994)
J. Cell Sci.
, vol.107
, pp. 719-726
-
-
Willnow, T.E.1
Herz, J.2
-
30
-
-
0034050724
-
Syndecan-4 deficiency impairs focal adhesion formation only under restricted conditions
-
DOI 10.1074/jbc.275.8.5249
-
Ishiguro, K., Kadomatsu, K., Kojima, T., Muramatsu, H., Tsuzuki, S., Nakamura, E., Kusugami, K., Saito, H., and Muramatsu, T. (2000) Syndecan-4 deficiency impairs focal adhesion formation only under restricted conditions. J. Biol. Chem. 275, 5249-5252 (Pubitemid 30115150)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.8
, pp. 5249-5252
-
-
Ishiguro, K.1
Kadomatsu, K.2
Kojima, T.3
Muramatsu, H.4
Tsuzuki, S.5
Nakamura, E.6
Kusugami, K.7
Saito, H.8
Muramatsu, T.9
-
31
-
-
0345735683
-
TIMP-3 inhibits aggrecanase-mediated glycosaminoglycan release from cartilage explants stimulated by catabolic factors
-
DOI 10.1016/S0014-5793(03)01295-X
-
Gendron, C., Kashiwagi, M., Hughes, C., Caterson, B., and Nagase, H. (2003) TIMP-3 inhibits aggrecanase-mediated glycosaminoglycan release from cartilage explants stimulated by catabolic factors. FEBS Lett. 555, 431-436 (Pubitemid 37532588)
-
(2003)
FEBS Letters
, vol.555
, Issue.3
, pp. 431-436
-
-
Gendron, C.1
Kashiwagi, M.2
Hughes, C.3
Caterson, B.4
Nagase, H.5
-
32
-
-
0030863621
-
Soluble low density lipoprotein receptor-related protein (LRP) circulates in human plasma
-
DOI 10.1074/jbc.272.38.23946
-
Quinn, K. A., Grimsley, P. G., Dai, Y. P., Tapner, M., Chesterman, C. N., and Owensby, D. A. (1997) Soluble low density lipoprotein receptor-related protein (LRP) circulates in human plasma. J. Biol. Chem. 272, 23946-23951 (Pubitemid 27410977)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.38
, pp. 23946-23951
-
-
Quinn, K.A.1
Grimsley, P.G.2
Dai, Y.-P.3
Tapner, M.4
Chesterman, C.N.5
Owensby, D.A.6
-
33
-
-
0032722310
-
Syndecan-4 core protein is sufficient for the assembly of focal adhesions and actin stress fibers
-
Echtermeyer, F., Baciu, P. C., Saoncella, S., Ge, Y., and Goetinck, P. F. (1999) Syndecan-4 core protein is sufficient for the assembly of focal adhesions and actin stress fibers. J. Cell Sci. 112, 3433-3441
-
(1999)
J. Cell Sci.
, vol.112
, pp. 3433-3441
-
-
Echtermeyer, F.1
Baciu, P.C.2
Saoncella, S.3
Ge, Y.4
Goetinck, P.F.5
-
34
-
-
0038297557
-
Tissue inhibitor of metalloproteinases-3 induces apoptosis in melanoma cells by stabilization of death receptors
-
DOI 10.1038/sj.onc.1206292
-
Ahonen, M., Poukkula, M., Baker, A. H., Kashiwagi, M., Nagase, H., Eriksson, J. E., and Kähäri, V. M. (2003) Tissue inhibitor of metalloproteinases-3 induces apoptosis in melanoma cells by stabilization of death receptors. Oncogene 22, 2121-2134 (Pubitemid 36539562)
-
(2003)
Oncogene
, vol.22
, Issue.14
, pp. 2121-2134
-
-
Ahonen, M.1
Poukkula, M.2
Baker, A.H.3
Kashiwagi, M.4
Nagase, H.5
Eriksson, J.E.6
Kahari, V.-M.7
-
35
-
-
77957866595
-
Inflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophages
-
Gorovoy, M., Gaultier, A., Campana, W. M., Firestein, G. S., and Gonias, S. L. (2010) Inflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophages. J. Leukocyte Biol. 88, 769-778
-
(2010)
J. Leukocyte Biol.
, vol.88
, pp. 769-778
-
-
Gorovoy, M.1
Gaultier, A.2
Campana, W.M.3
Firestein, G.S.4
Gonias, S.L.5
-
36
-
-
80051685667
-
Cell cholesterol modulates metalloproteinase-dependent shedding of low density lipoprotein receptor-related protein-1 (LRP-1) and clearance function
-
Selvais, C., D'Auria, L., Tyteca, D., Perrot, G., Lemoine, P., Troeberg, L., Dedieu, S., Noël, A., Nagase, H., Henriet, P., Courtoy, P. J., Marbaix, E., and Emonard, H. (2011) Cell cholesterol modulates metalloproteinase- dependent shedding of low density lipoprotein receptor-related protein-1 (LRP-1) and clearance function. FASEB J. 25, 2770-2781
-
(2011)
FASEB J.
, vol.25
, pp. 2770-2781
-
-
Selvais, C.1
D'Auria, L.2
Tyteca, D.3
Perrot, G.4
Lemoine, P.5
Troeberg, L.6
Dedieu, S.7
Noël, A.8
Nagase, H.9
Henriet, P.10
Courtoy, P.J.11
Marbaix, E.12
Emonard, H.13
-
37
-
-
24044497252
-
The low density lipoprotein receptor-related protein (LRP) is a novel β-secretase (BACE1) substrate
-
DOI 10.1074/jbc.M414248200
-
von Arnim, C. A., Kinoshita, A., Peltan, I. D., Tangredi, M. M., Herl, L., Lee, B. M., Spoelgen, R., Hshieh, T. T., Ranganathan, S., Battey, F. D., Liu, C. X., Bacskai, B. J., Sever, S., Irizarry, M. C., Strickland, D. K., and Hyman, B. T. (2005) The low density lipoprotein receptor-related protein (LRP) is a novel β-secretase (BACE1) substrate. J. Biol. Chem. 280, 17777-17785 (Pubitemid 41389016)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.18
, pp. 17777-17785
-
-
Von Arnim, C.A.F.1
Kinoshita, A.2
Peltan, I.D.3
Tangredi, M.M.4
Herl, L.5
Lee, B.M.6
Spoelgen, R.7
Hshieh, T.T.8
Ranganathan, S.9
Battey, F.D.10
Liu, C.-X.11
Bacskai, B.J.12
Sever, S.13
Irizarry, M.C.14
Strickland, D.K.15
Hyman, B.T.16
-
38
-
-
1042301387
-
The Low Density Lipoprotein Receptor-related Protein LRP Is Regulated by Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) Proteolysis in Malignant Cells
-
DOI 10.1074/jbc.M311569200
-
Rozanov, D. V., Hahn-Dantona, E., Strickland, D. K., and Strongin, A. Y. (2004) The low density lipoprotein receptor-related protein LRP is regulated by membrane type-1 matrix metalloproteinase (MT1-MMP) proteolysis in malignant cells. J. Biol. Chem. 279, 4260-4268 (Pubitemid 38199013)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.6
, pp. 4260-4268
-
-
Rozanov, D.V.1
Hahn-Dantona, E.2
Strickland, D.K.3
Strongin, A.Y.4
-
39
-
-
0033568616
-
Characterization of the soluble form of the low density lipoprotein receptor-related protein (LRP)
-
DOI 10.1006/excr.1999.4590
-
Quinn, K. A., Pye, V. J., Dai, Y. P., Chesterman, C. N., and Owensby, D. A. (1999) Characterization of the soluble form of the low density lipoprotein receptor-related protein (LRP). Exp. Cell Res. 251, 433-441 (Pubitemid 29431880)
-
(1999)
Experimental Cell Research
, vol.251
, Issue.2
, pp. 433-441
-
-
Quinn, K.A.1
Pye, V.J.2
Dai, Y.-P.3
Chesterman, C.N.4
Owensby, D.A.5
-
40
-
-
0037417411
-
uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion
-
DOI 10.1083/jcb.200211091
-
Engelholm, L. H., List, K., Netzel-Arnett, S., Cukierman, E., Mitola, D. J., Aaronson, H., Kjøller, L., Larsen, J. K., Yamada, K. M., Strickland, D. K., Holmbeck, K., Danø, K., Birkedal-Hansen, H., Behrendt, N., and Bugge, T. H. (2003) uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion. J. Cell Biol. 160, 1009-1015 (Pubitemid 36443870)
-
(2003)
Journal of Cell Biology
, vol.160
, Issue.7
, pp. 1009-1015
-
-
Engelholm, L.H.1
List, K.2
Netzel-Arnett, S.3
Cukierman, E.4
Mitola, D.J.5
Aaronson, H.6
Kjoller, L.7
Larsen, J.K.8
Yamada, K.M.9
Strickland, D.K.10
Holmbeck, K.11
Dano, K.12
Birkedal-Hansen, H.13
Behrendt, N.14
Bugge, T.H.15
-
41
-
-
0347320581
-
uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV
-
DOI 10.1016/j.yexcr.2003.10.008
-
Kjøller, L., Engelholm, L. H., Høyer-Hansen, M., Danø, K., Bugge, T. H., and Behrendt, N. (2004) uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV. Exp. Cell Res. 293, 106-116 (Pubitemid 38064418)
-
(2004)
Experimental Cell Research
, vol.293
, Issue.1
, pp. 106-116
-
-
Kjoller, L.1
Engelholm, L.H.2
Hoyer-Hansen, M.3
Dano, K.4
Bugge, T.H.5
Behrendt, N.6
-
42
-
-
0035805530
-
The low density lipoprotein receptor-related protein modulates levels of matrix metalloproteinase 9 (MMP-9) by mediating its cellular catabolism
-
Hahn-Dantona, E., Ruiz, J. F., Bornstein, P., and Strickland, D. K. (2001) The low density lipoprotein receptor-related protein modulates levels of matrix metalloproteinase 9 (MMP-9) by mediating its cellular catabolism. J. Biol. Chem. 276, 15498-15503
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 15498-15503
-
-
Hahn-Dantona, E.1
Ruiz, J.F.2
Bornstein, P.3
Strickland, D.K.4
-
43
-
-
19944428578
-
Low density lipoprotein receptor-related protein mediates endocytic clearance of pro-MMP-2-TIMP-2 complex through a thrombospondin-independent mechanism
-
DOI 10.1074/jbc.M406792200
-
Emonard, H., Bellon, G., Troeberg, L., Berton, A., Robinet, A., Henriet, P., Marbaix, E., Kirkegaard, K., Patthy, L., Eeckhout, Y., Nagase, H., Hornebeck, W., and Courtoy, P. J. (2004) Low density lipoprotein receptorrelated protein mediates endocytic clearance of pro-MMP-2·TIMP-2 complex through a thrombospondin-independent mechanism. J. Biol. Chem. 279, 54944-54951 (Pubitemid 40053241)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.52
, pp. 54944-54951
-
-
Emonard, H.1
Bellon, G.2
Troeberg, L.3
Berton, A.4
Robinet, A.5
Henriet, P.6
Marbaix, E.7
Kirkegaard, K.8
Patthy, L.9
Eeckhout, Y.10
Nagase, H.11
Hornebeck, W.12
Courtoy, P.J.13
-
44
-
-
70449408083
-
Syndecan-1 is the primary heparan sulfate proteoglycan mediating hepatic clearance of triglyceride-rich lipoproteins in mice
-
Stanford, K. I., Bishop, J. R., Foley, E. M., Gonzales, J. C., Niesman, I. R., Witztum, J. L., and Esko, J. D. (2009) Syndecan-1 is the primary heparan sulfate proteoglycan mediating hepatic clearance of triglyceride-rich lipoproteins in mice. J. Clin. Invest. 119, 3236-3245
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3236-3245
-
-
Stanford, K.I.1
Bishop, J.R.2
Foley, E.M.3
Gonzales, J.C.4
Niesman, I.R.5
Witztum, J.L.6
Esko, J.D.7
-
45
-
-
13844292108
-
Internalization but not binding of thrombospondin-1 to low density lipoprotein receptor-related protein-1 requires heparan sulfate proteoglycans
-
Wang, S., Herndon, M. E., Ranganathan, S., Godyna, S., Lawler, J., Argraves, W. S., and Liau, G. (2004) Internalization but not binding of thrombospondin-1 to low density lipoprotein receptor-related protein-1 requires heparan sulfate proteoglycans. J. Cell. Biochem. 91, 766-776
-
(2004)
J. Cell. Biochem.
, vol.91
, pp. 766-776
-
-
Wang, S.1
Herndon, M.E.2
Ranganathan, S.3
Godyna, S.4
Lawler, J.5
Argraves, W.S.6
Liau, G.7
-
46
-
-
0030705207
-
Tissue factor pathway inhibitor endocytosis
-
DOI 10.1016/S1050-1738(97)00083-2, PII S1050173897000832
-
Schwartz, A. L., and Broze, G. J., Jr. (1997) Tissue factor pathway inhibitor endocytosis. Trends Cardiovasc. Med. 7, 234-239 (Pubitemid 27459042)
-
(1997)
Trends in Cardiovascular Medicine
, vol.7
, Issue.7
, pp. 234-239
-
-
Schwartz, A.L.1
Broze Jr., G.J.2
-
47
-
-
79551565625
-
Heparan sulphate proteoglycan and the low density lipoprotein receptor-related protein 1 constitute major pathways for neuronal amyloid-β uptake
-
Kanekiyo, T., Zhang, J., Liu, Q., Liu, C. C., Zhang, L., and Bu, G. (2011) Heparan sulphate proteoglycan and the low density lipoprotein receptor-related protein 1 constitute major pathways for neuronal amyloid-β uptake. J. Neurosci. 31, 1644-1651
-
(2011)
J. Neurosci.
, vol.31
, pp. 1644-1651
-
-
Kanekiyo, T.1
Zhang, J.2
Liu, Q.3
Liu, C.C.4
Zhang, L.5
Bu, G.6
-
48
-
-
0035853843
-
Cell surface heparan sulfate proteoglycans participate in factor VIII catabolism mediated by low density lipoprotein receptor-related protein
-
Sarafanov, A. G., Ananyeva, N. M., Shima, M., and Saenko, E. L. (2001) Cell surface heparan sulfate proteoglycans participate in factor VIII catabolism mediated by low density lipoprotein receptor-related protein. J. Biol. Chem. 276, 11970-11979
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 11970-11979
-
-
Sarafanov, A.G.1
Ananyeva, N.M.2
Shima, M.3
Saenko, E.L.4
-
49
-
-
0034670013
-
Activation of factor IX zymogen results in exposure of a binding site for low density lipoprotein receptor-related protein
-
Neels, J. G., van Den Berg, B. M., Mertens, K., ter Maat, H., Pannekoek, H., van Zonneveld, A. J., and Lenting, P. J. (2000) Activation of factor IX zymogen results in exposure of a binding site for low density lipoprotein receptor-related protein. Blood 96, 3459-3465
-
(2000)
Blood
, vol.96
, pp. 3459-3465
-
-
Neels, J.G.1
Van Den Berg, B.M.2
Mertens, K.3
Ter Maat, H.4
Pannekoek, H.5
Van Zonneveld, A.J.6
Lenting, P.J.7
-
50
-
-
33947706206
-
Apolipoprotein A-V interaction with members of the low density lipoprotein receptor gene family
-
DOI 10.1021/bi7000533
-
Nilsson, S. K., Lookene, A., Beckstead, J. A., Gliemann, J., Ryan, R. O., and Olivecrona, G. (2007) Apolipoprotein A-V interaction with members of the low density lipoprotein receptor gene family. Biochemistry 46, 3896-3904 (Pubitemid 46493490)
-
(2007)
Biochemistry
, vol.46
, Issue.12
, pp. 3896-3904
-
-
Nilsson, S.K.1
Lookene, A.2
Beckstead, J.A.3
Gliemann, J.4
Ryan, R.O.5
Olivecrona, G.6
-
51
-
-
0037169492
-
The α-chains of C4b-binding protein mediate complex formation with low density lipoprotein receptor-related protein
-
DOI 10.1074/jbc.M102293200
-
Westein, E., Denis, C. V., Bouma, B. N., and Lenting, P. J. (2002) The α-chains of C4b-binding protein mediate complex formation with lowdensity lipoprotein receptor-related protein. J. Biol. Chem. 277, 2511-2516 (Pubitemid 34953274)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.4
, pp. 2511-2516
-
-
Westein, E.1
Denis, C.V.2
Bouma, B.N.3
Lenting, P.J.4
-
52
-
-
0001353920
-
Purified α2-macroglobulin receptor/LDL receptor-relatedprotein binds urokinase-plasminogen activator inhibitor type-1 complex: Evidence that the α2-macroglobulin receptor mediates cellular degradationof urokinase receptor-bound complexes
-
Nykjaer, A., Petersen, C. M., Møller, B., Jensen, P. H., Moestrup, S. K., Holtet, T. L., Etzerodt, M., Thøgersen, H. C., Munch, M., and Andreasen, P. A. (1992) Purified α2-macroglobulin receptor/LDL receptor-relatedprotein binds urokinase-plasminogen activator inhibitor type-1 complex: evidence that the α2-macroglobulin receptor mediates cellular degradationof urokinase receptor-bound complexes. J. Biol. Chem. 267, 14543-14546
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 14543-14546
-
-
Nykjaer, A.1
Petersen, C.M.2
Møller, B.3
Jensen, P.H.4
Moestrup, S.K.5
Holtet, T.L.6
Etzerodt, M.7
Thøgersen, H.C.8
Munch, M.9
Andreasen, P.A.10
-
53
-
-
0031743824
-
Plasminogen activator inhibitor 1 contains a cryptic high affinity receptor binding site that is exposed upon complex formation with tissue-type plasminogen activator
-
Horn, I. R., van den berg, B. M., Moestrup, S. K., Pannekoek, H., and van Zonneveld, A. J. (1998) Plasminogen activator inhibitor 1 contains a cryptic high affinity receptor binding site that is exposed upon complex formation with tissue-type plasminogen activator. Thromb. Haemost. 80, 822-828
-
(1998)
Thromb. Haemost.
, vol.80
, pp. 822-828
-
-
Horn, I.R.1
Van Den Berg, B.M.2
Moestrup, S.K.3
Pannekoek, H.4
Van Zonneveld, A.J.5
-
54
-
-
0032513248
-
Plasminogen activator inhibitor-1 contains a cryptic high affinity binding site for the low density lipoprotein receptor-related protein
-
DOI 10.1074/jbc.273.11.6358
-
Stefansson, S., Muhammad, S., Cheng, X. F., Battey, F. D., Strickland, D. K., and Lawrence, D. A. (1998) Plasminogen activator inhibitor-1 contains a cryptic high affinity binding site for the low density lipoprotein receptor-related protein. J. Biol. Chem. 273, 6358-6366 (Pubitemid 28144727)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.11
, pp. 6358-6366
-
-
Stefansson, S.1
Muhammad, S.2
Cheng, X.-F.3
Battey, F.D.4
Strickland, D.K.5
Lawrence, D.A.6
-
55
-
-
56649100319
-
The structure of glycosaminoglycans and their interactions with proteins
-
Gandhi, N. S., and Mancera, R. L. (2008) The structure of glycosaminoglycans and their interactions with proteins. Chem. Biol. Drug Des. 72, 455-482
-
(2008)
Chem. Biol. Drug Des.
, vol.72
, pp. 455-482
-
-
Gandhi, N.S.1
Mancera, R.L.2
-
56
-
-
33646046808
-
Structure of an LDLR-RAP complex reveals a general mode for ligand recognition by lipoprotein receptors
-
Fisher, C., Beglova, N., and Blacklow, S. C. (2006) Structure of an LDLR-RAP complex reveals a general mode for ligand recognition by lipoprotein receptors. Mol. Cell 22, 277-283
-
(2006)
Mol. Cell
, vol.22
, pp. 277-283
-
-
Fisher, C.1
Beglova, N.2
Blacklow, S.C.3
-
57
-
-
79751538197
-
A single lysine of the two-lysine recognition motif of the D3 domain of receptor-associated protein is sufficient to mediate endocytosis by low density lipoprotein receptor-related protein
-
van den Biggelaar, M., Sellink, E., Klein Gebbinck, J. W., Mertens, K., and Meijer, A. B. (2011) A single lysine of the two-lysine recognition motif of the D3 domain of receptor-associated protein is sufficient to mediate endocytosis by low density lipoprotein receptor-related protein. Int. J. Biochem. Cell Biol. 43, 431-440
-
(2011)
Int. J. Biochem. Cell Biol.
, vol.43
, pp. 431-440
-
-
Van Den Biggelaar, M.1
Sellink, E.2
Klein Gebbinck, J.W.3
Mertens, K.4
Meijer, A.B.5
-
58
-
-
19444365227
-
2- macroglobulin blocks binding to the low density lipoprotein receptor-related protein-1
-
DOI 10.1016/j.abb.2005.03.019, PII S0003986105001359
-
Arandjelovic, S., Hall, B. D., and Gonias, S. L. (2005) Mutation of lysine 1370 in full-length human α2-macroglobulin blocks binding to the lowdensity lipoprotein receptor-related protein-1. Arch Biochem. Biophys. 438, 29-35 (Pubitemid 40725205)
-
(2005)
Archives of Biochemistry and Biophysics
, vol.438
, Issue.1
, pp. 29-35
-
-
Arandjelovic, S.1
Hall, B.D.2
Gonias, S.L.3
|