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Volumn 24, Issue 1, 2013, Pages 65-73

Quinpirole and 8-OH-DPAT induce compulsive checking behavior in male rats by acting on different functional parts of an OCD neurocircuit

Author keywords

compulsive checking behavior; dopamine serotonin interaction; obsessive compulsive disorder; rat; security motivation

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; QUINPIROLE;

EID: 84872075489     PISSN: 09558810     EISSN: 14735849     Source Type: Journal    
DOI: 10.1097/FBP.0b013e32835d5b7a     Document Type: Article
Times cited : (35)

References (59)
  • 1
    • 84893048020 scopus 로고    scopus 로고
    • Modifying 5-HT1A receptor gene expression as a new target for antidepressant therapy
    • Article 35
    • Albert PR, Le François B (2010). Modifying 5-HT1A receptor gene expression as a new target for antidepressant therapy. Front Neurosci 4:Article 35.
    • (2010) Front Neurosci , vol.4
    • Albert, P.R.1    Le François, B.2
  • 2
    • 33846426067 scopus 로고    scopus 로고
    • Pharmacologic mechanisms of serotonergic regulation of dopamine neurotransmission
    • Alex KD, Pehek EA (2007). Pharmacologic mechanisms of serotonergic regulation of dopamine neurotransmission. Pharmacol Ther 113:296-320.
    • (2007) Pharmacol Ther , vol.113 , pp. 296-320
    • Alex, K.D.1    Pehek, E.A.2
  • 3
    • 2342537848 scopus 로고    scopus 로고
    • Pathophysiology of obsessive-compulsive disorder: A necessary link between phenomenology, neuropsychology, imagery and physiology
    • Aouizerate B, Guehl D, Cuny E, Rougier A, Bioulac B, Tignol J, et al. (2004). Pathophysiology of obsessive-compulsive disorder: a necessary link between phenomenology, neuropsychology, imagery and physiology. Prog Neurobiol 72:195-221.
    • (2004) Prog Neurobiol , vol.72 , pp. 195-221
    • Aouizerate, B.1    Guehl, D.2    Cuny, E.3    Rougier, A.4    Bioulac, B.5    Tignol, J.6
  • 4
    • 0032970989 scopus 로고    scopus 로고
    • A review of central 5-HT receptors and their function
    • Barnes NM, Sharp T (1999). A review of central 5-HT receptors and their function. Neuropharmacology 38:1083-1152.
    • (1999) Neuropharmacology , vol.38 , pp. 1083-1152
    • Barnes, N.M.1    Sharp, T.2
  • 5
    • 0027074323 scopus 로고
    • Neuroimaging studies of obsessive compulsive disorder
    • Baxter LR Jr. (1992). Neuroimaging studies of obsessive compulsive disorder. Psychiatr Clin North Am 15:871-884.
    • (1992) Psychiatr Clin North Am , vol.15 , pp. 871-884
    • Baxter Jr., L.R.1
  • 6
    • 53849146695 scopus 로고    scopus 로고
    • Effects of salvinorin A on locomotor sensitization to D2/D3 dopamine agonist quinpirole
    • Beerepoot P, Lam V, Luu A, Tsoi B, Siebert D, Szechtman H (2008). Effects of salvinorin A on locomotor sensitization to D2/D3 dopamine agonist quinpirole. Neurosci Lett 446:101-104.
    • (2008) Neurosci Lett , vol.446 , pp. 101-104
    • Beerepoot, P.1    Lam, V.2    Luu, A.3    Tsoi, B.4    Siebert, D.5    Szechtman, H.6
  • 7
    • 0035208451 scopus 로고    scopus 로고
    • The morphogenesis of motor rituals in rats treated chronically with the dopamine agonist quinpirole
    • Ben Pazi A, Szechtman H, Eilam D (2001). The morphogenesis of motor rituals in rats treated chronically with the dopamine agonist quinpirole. Behav Neurosci 115:1301-1317.
    • (2001) Behav Neurosci , vol.115 , pp. 1301-1317
    • Ben Pazi, A.1    Szechtman, H.2    Eilam, D.3
  • 8
    • 33947411763 scopus 로고    scopus 로고
    • Why ritualized behavior? Precaution systems and action parsing in developmental, pathological and cultural rituals
    • Boyer P, Lienard P (2006). Why ritualized behavior? Precaution systems and action parsing in developmental, pathological and cultural rituals. Behav Brain Sci 29:595-613.
    • (2006) Behav Brain Sci , vol.29 , pp. 595-613
    • Boyer, P.1    Lienard, P.2
  • 9
    • 84872073307 scopus 로고
    • Canadian Council on Animal Care 2nd ed. Ottawa, Ontario: CCAC
    • Canadian Council on Animal Care (1993). Guide to the care and use of experimental animals. Vol. 1. 2nd ed. Ottawa, Ontario: CCAC.
    • (1993) Guide to the Care and Use of Experimental Animals , vol.1
  • 10
    • 79251557170 scopus 로고    scopus 로고
    • Activity modulation of the globus pallidus and the nucleus entopeduncularis affects compulsive checking in rats
    • Djodari-Irani A, Klein J, Banzhaf J, Joel D, Heinz A, Harnack D, et al. (2011). Activity modulation of the globus pallidus and the nucleus entopeduncularis affects compulsive checking in rats. Behav Brain Res 219:149-158.
    • (2011) Behav Brain Res , vol.219 , pp. 149-158
    • Djodari-Irani, A.1    Klein, J.2    Banzhaf, J.3    Joel, D.4    Heinz, A.5    Harnack, D.6
  • 11
    • 0034829038 scopus 로고    scopus 로고
    • SEE: A tool for the visualization and analysis of rodent exploratory behavior
    • Drai D, Golani I (2001). SEE: a tool for the visualization and analysis of rodent exploratory behavior. Neurosci Biobehav Rev 25:409-426.
    • (2001) Neurosci Biobehav Rev , vol.25 , pp. 409-426
    • Drai, D.1    Golani, I.2
  • 12
    • 0034654483 scopus 로고    scopus 로고
    • Statistical discrimination of natural modes of motion in rat exploratory behavior
    • Drai D, Benjamini Y, Golani I (2000). Statistical discrimination of natural modes of motion in rat exploratory behavior. J Neurosci Methods 96:119-131.
    • (2000) J Neurosci Methods , vol.96 , pp. 119-131
    • Drai, D.1    Benjamini, Y.2    Golani, I.3
  • 13
    • 33645069657 scopus 로고    scopus 로고
    • Development and temporal organization of compulsive checking induced by repeated injections of the dopamine agonist quinpirole in an animal model of obsessive-compulsive disorder
    • Dvorkin A, Perreault ML, Szechtman H (2006). Development and temporal organization of compulsive checking induced by repeated injections of the dopamine agonist quinpirole in an animal model of obsessive-compulsive disorder. Behav Brain Res 169:303-311.
    • (2006) Behav Brain Res , vol.169 , pp. 303-311
    • Dvorkin, A.1    Perreault, M.L.2    Szechtman, H.3
  • 14
    • 78149255370 scopus 로고    scopus 로고
    • Features of compulsive checking behavior mediated by nucleus accumbens and orbital frontal cortex
    • Dvorkin A, Silva C, McMurran T, Bisnaire L, Foster J, Szechtman H (2010). Features of compulsive checking behavior mediated by nucleus accumbens and orbital frontal cortex. Eur J Neurosci 32:1552-1563.
    • (2010) Eur J Neurosci , vol.32 , pp. 1552-1563
    • Dvorkin, A.1    Silva, C.2    McMurran, T.3    Bisnaire, L.4    Foster, J.5    Szechtman, H.6
  • 15
    • 0004265660 scopus 로고
    • 2nd ed. Rev. with 17 programs. Oxford Oxfordshire: B Blackwell
    • Ebdon D (1985). Statistics in geography. 2nd ed. Rev. with 17 programs. Oxford, Oxfordshire: B. Blackwell.
    • (1985) Statistics in Geography
    • Ebdon, D.1
  • 16
    • 0024414254 scopus 로고
    • Home base behavior of rats (Rattus norvegicus) exploring a novel environment
    • Eilam D, Golani I (1989). Home base behavior of rats (Rattus norvegicus) exploring a novel environment. Behav Brain Res 34:199-211.
    • (1989) Behav Brain Res , vol.34 , pp. 199-211
    • Eilam, D.1    Golani, I.2
  • 17
    • 16844379173 scopus 로고    scopus 로고
    • Psychostimulant-induced behavior as an animal model of obsessive-compulsive disorder: An ethological approach to the form of compulsive rituals
    • Eilam D, Szechtman H (2005). Psychostimulant-induced behavior as an animal model of obsessive-compulsive disorder: an ethological approach to the form of compulsive rituals. CNS Spectr 10:191-202.
    • (2005) CNS Spectr , vol.10 , pp. 191-202
    • Eilam, D.1    Szechtman, H.2
  • 18
    • 0028816558 scopus 로고
    • Perseveration without hyperlocomotion in a spontaneous alternation task in rats sensitized to the dopamine agonist quinpirole
    • Einat H, Szechtman H (1995). Perseveration without hyperlocomotion in a spontaneous alternation task in rats sensitized to the dopamine agonist quinpirole. Physiol Behav 57:55-59.
    • (1995) Physiol Behav , vol.57 , pp. 55-59
    • Einat, H.1    Szechtman, H.2
  • 19
    • 33747066901 scopus 로고    scopus 로고
    • The normalcy of neurosis: Evolutionary origins of obsessive-compulsive disorder and related behaviors
    • Feygin DL, Swain JE, Leckman JF (2006). The normalcy of neurosis: evolutionary origins of obsessive-compulsive disorder and related behaviors. Prog Neuropsychopharmacol Biol Psychiatry 30:854-864.
    • (2006) Prog Neuropsychopharmacol Biol Psychiatry , vol.30 , pp. 854-864
    • Feygin, D.L.1    Swain, J.E.2    Leckman, J.F.3
  • 20
    • 37549064027 scopus 로고    scopus 로고
    • 5-HT receptor regulation of neurotransmitter release
    • Fink KB, Gö thert M (2007). 5-HT receptor regulation of neurotransmitter release. Pharmacol Rev 59:360-417.
    • (2007) Pharmacol Rev , vol.59 , pp. 360-417
    • Fink, K.B.1    Göthert, M.2
  • 21
    • 19944426181 scopus 로고    scopus 로고
    • Randomized, placebo-controlled trial of exposure and ritual prevention, clomipramine, and their combination in the treatment of obsessive-compulsive disorder
    • Foa EB, Liebowitz MR, Kozak MJ, Davies S, Campeas R, Franklin ME, et al. (2005). Randomized, placebo-controlled trial of exposure and ritual prevention, clomipramine, and their combination in the treatment of obsessive-compulsive disorder. Am J Psychiatry 162:151-161.
    • (2005) Am J Psychiatry , vol.162 , pp. 151-161
    • Foa, E.B.1    Liebowitz, M.R.2    Kozak, M.J.3    Davies, S.4    Campeas, R.5    Franklin, M.E.6
  • 22
    • 0027458604 scopus 로고
    • Stopping behavior: Constraints on exploration in rats (Rattus norvegicus
    • Golani I, Benjamini Y, Eilam D (1993). Stopping behavior: constraints on exploration in rats (Rattus norvegicus). Behav Brain Res 53:21-33.
    • (1993) Behav Brain Res , vol.53 , pp. 21-33
    • Golani, I.1    Benjamini, Y.2    Eilam, D.3
  • 23
    • 0033636505 scopus 로고    scopus 로고
    • Toward a neurobiology of obsessive-compulsive disorder
    • Graybiel AM, Rauch SL (2000). Toward a neurobiology of obsessive-compulsive disorder. Neuron 28:343-347.
    • (2000) Neuron , vol.28 , pp. 343-347
    • Graybiel, A.M.1    Rauch, S.L.2
  • 25
    • 79954589565 scopus 로고    scopus 로고
    • 5-HT receptors and reward-related behaviour: A review
    • Hayes DJ, Greenshaw AJ (2011). 5-HT receptors and reward-related behaviour: a review. Neurosci Biobehav Rev 35:1419-1449.
    • (2011) Neurosci Biobehav Rev , vol.35 , pp. 1419-1449
    • Hayes, D.J.1    Greenshaw, A.J.2
  • 26
    • 0742272070 scopus 로고    scopus 로고
    • The dynamics of spatial behavior how can robust smoothing techniques help?
    • Hen I, Sakov A, Kafkafi N, Golani I, Benjamini Y (2004). The dynamics of spatial behavior: how can robust smoothing techniques help? J Neurosci Methods 133:161-172.
    • (2004) J Neurosci Methods , vol.133 , pp. 161-172
    • Hen, I.1    Sakov, A.2    Kafkafi, N.3    Golani, I.4    Benjamini, Y.5
  • 27
    • 84856289525 scopus 로고    scopus 로고
    • When too much is not enough: Obsessive-compulsive disorder as a pathology of stopping, rather than starting
    • Hinds AL, Woody EZ, Van Ameringen M, Schmidt LA, Szechtman H (2012). When too much is not enough: obsessive-compulsive disorder as a pathology of stopping, rather than starting. PLoS One 7:e30586.
    • (2012) PLoS One , vol.7
    • Hinds, A.L.1    Woody, E.Z.2    Van Ameringen, M.3    Schmidt, L.A.4    Szechtman, H.5
  • 28
    • 79959460577 scopus 로고    scopus 로고
    • Animal models of obsessive compulsive disorder: Recent findings and future directions
    • Hoffman KL (2011). Animal models of obsessive compulsive disorder: recent findings and future directions. Expert Opin Drug Discov 6:725-737.
    • (2011) Expert Opin Drug Discov , vol.6 , pp. 725-737
    • Hoffman, K.L.1
  • 30
    • 0027055218 scopus 로고
    • Neurobiology of obsessive compulsive disorder: A review
    • Insel TR (1992). Neurobiology of obsessive compulsive disorder: a review. Int Clin Psychopharmacol 7 (Suppl 1):31-33.
    • (1992) Int Clin Psychopharmacol , vol.7 , Issue.SUPPL. 1 , pp. 31-33
    • Insel, T.R.1
  • 31
    • 33646032703 scopus 로고    scopus 로고
    • Current animal models of obsessive compulsive disorder: A critical review
    • Joel D (2006). Current animal models of obsessive compulsive disorder: a critical review. Prog Neuropsychopharmacol Biol Psychiatry 30:374-388.
    • (2006) Prog Neuropsychopharmacol Biol Psychiatry , vol.30 , pp. 374-388
    • Joel, D.1
  • 32
    • 33748092384 scopus 로고    scopus 로고
    • Animal models of obsessive-compulsive disorder: Rationale to understanding psychobiology and pharmacology
    • Korff S, Harvey BH (2006). Animal models of obsessive-compulsive disorder: rationale to understanding psychobiology and pharmacology. Psychiatr Clin North Am 29:371-390.
    • (2006) Psychiatr Clin North Am , vol.29 , pp. 371-390
    • Korff, S.1    Harvey, B.H.2
  • 35
    • 0024427173 scopus 로고
    • Neurophysiologic dysfunction in basal ganglia/limbic striatal and thalamocortical circuits as a pathogenetic mechanism of obsessive-compulsive disorder
    • Modell JG, Mountz JM, Curtis GC, Greden JF (1989). Neurophysiologic dysfunction in basal ganglia/limbic striatal and thalamocortical circuits as a pathogenetic mechanism of obsessive-compulsive disorder. J Neuropsychiatry Clin Neurosci 1:27-36.
    • (1989) J Neuropsychiatry Clin Neurosci , vol.1 , pp. 27-36
    • Modell, J.G.1    Mountz, J.M.2    Curtis, G.C.3    Greden, J.F.4
  • 36
    • 67449094653 scopus 로고    scopus 로고
    • High-frequency stimulation of the nucleus accumbens core and shell reduces quinpirole-induced compulsive checking in rats
    • Mundt A, Klein J, Joel D, Heinz A, Djodari-Irani A, Harnack D, et al. (2009). High-frequency stimulation of the nucleus accumbens core and shell reduces quinpirole-induced compulsive checking in rats. Eur J Neurosci 29: 2401-2412.
    • (2009) Eur J Neurosci , vol.29 , pp. 2401-2412
    • Mundt, A.1    Klein, J.2    Joel, D.3    Heinz, A.4    Djodari-Irani, A.5    Harnack, D.6
  • 37
    • 0035432701 scopus 로고    scopus 로고
    • EthoVision: A versatile video tracking system for automation of behavioral experiments
    • Noldus LP, Spink AJ, Tegelenbosch RA (2001). EthoVision: a versatile video tracking system for automation of behavioral experiments. Behav Res Methods InstrumComput 33:398-414.
    • (2001) Behav Res Methods InstrumComput , vol.33 , pp. 398-414
    • Noldus, L.P.1    Spink, A.J.2    Tegelenbosch, R.A.3
  • 38
    • 33747341585 scopus 로고    scopus 로고
    • Kappa-opioid agonist U69593 potentiates locomotor sensitization to the D2/D3 agonist quinpirole: Pre-and postsynaptic mechanisms
    • Perreault ML, Graham D, Bisnaire L, Simms J, Hayton S, Szechtman H (2005). Kappa-opioid agonist U69593 potentiates locomotor sensitization to the D2/D3 agonist quinpirole: pre-and postsynaptic mechanisms. Neuropsychopharmacology 31:1967-1981.
    • (2005) Neuropsychopharmacology , vol.31 , pp. 1967-1981
    • Perreault, M.L.1    Graham, D.2    Bisnaire, L.3    Simms, J.4    Hayton, S.5    Szechtman, H.6
  • 39
    • 1542375920 scopus 로고    scopus 로고
    • Changes in compulsion and anxiety symptoms with nicotine transdermal patches in non-smoking obsessive-compulsive disorder patients
    • Salin-Pascual RJ, Basanez-Villa E (2003). Changes in compulsion and anxiety symptoms with nicotine transdermal patches in non-smoking obsessive-compulsive disorder patients. Rev Invest Clin 55:650-654.
    • (2003) Rev Invest Clin , vol.55 , pp. 650-654
    • Salin-Pascual, R.J.1    Basanez-Villa, E.2
  • 40
    • 0035318505 scopus 로고    scopus 로고
    • Brain-behavior relationships in obsessive-compulsive disorder
    • Saxena S, Bota RG, Brody AL (2001). Brain-behavior relationships in obsessive-compulsive disorder. Semin Clin Neuropsychiatry 6:82-101.
    • (2001) Semin Clin Neuropsychiatry , vol.6 , pp. 82-101
    • Saxena, S.1    Bota, R.G.2    Brody, A.L.3
  • 41
    • 0034831096 scopus 로고    scopus 로고
    • The EthoVision video tracking system-A tool for behavioral phenotyping of transgenic mice
    • Spink AJ, Tegelenbosch RA, Buma MO, Noldus LP (2001). The EthoVision video tracking system-a tool for behavioral phenotyping of transgenic mice. Physiol Behav 73:731-744.
    • (2001) Physiol Behav , vol.73 , pp. 731-744
    • Spink, A.J.1    Tegelenbosch, R.A.2    Buma, M.O.3    Noldus, L.P.4
  • 42
    • 0037014867 scopus 로고    scopus 로고
    • Obsessive-compulsive disorder
    • Stein DJ (2002). Obsessive-compulsive disorder. Lancet 360:397-405.
    • (2002) Lancet , vol.360 , pp. 397-405
    • Stein, D.J.1
  • 44
    • 0742323861 scopus 로고    scopus 로고
    • Obsessive-compulsive disorder as a disturbance of security motivation
    • Szechtman H, Woody E (2004). Obsessive-compulsive disorder as a disturbance of security motivation. Psychol Rev 111:111-127.
    • (2004) Psychol Rev , vol.111 , pp. 111-127
    • Szechtman, H.1    Woody, E.2
  • 45
    • 0028043115 scopus 로고
    • Effects of dose and interdose interval on locomotor sensitization to the dopamine agonist quinpirole
    • Szechtman H, Dai H, Mustafa S, Einat H, Sullivan RM (1994a). Effects of dose and interdose interval on locomotor sensitization to the dopamine agonist quinpirole. Pharmacol Biochem Behav 48:921-928.
    • (1994) Pharmacol Biochem Behav , vol.48 , pp. 921-928
    • Szechtman, H.1    Dai, H.2    Mustafa, S.3    Einat, H.4    Sullivan, R.M.5
  • 46
    • 0028360983 scopus 로고
    • Dynamics of behavioral sensitization induced by the dopamine agonist quinpirole and a proposed central energy control mechanism [published erratum appears in Psychopharmacology (Berl 1994 116(1):124]
    • Szechtman H, Talangbayan H, Canaran G, Dai H, Eilam D (1994b). Dynamics of behavioral sensitization induced by the dopamine agonist quinpirole and a proposed central energy control mechanism [published erratum appears in Psychopharmacology (Berl) 1994;116(1):124]. Psychopharmacology (Berl) 115:95-104.
    • (1994) Psychopharmacology (Berl) , vol.115 , pp. 95-104
    • Szechtman, H.1    Talangbayan, H.2    Canaran, G.3    Dai, H.4    Eilam, D.5
  • 47
    • 0032441547 scopus 로고    scopus 로고
    • Quinpirole induces compulsive checking behavior in rats: A potential animal model of obsessive-compulsive disorder (OCD
    • Szechtman H, Sulis W, Eilam D (1998). Quinpirole induces compulsive checking behavior in rats: a potential animal model of obsessive-compulsive disorder (OCD). Behav Neurosci 112:1475-1485.
    • (1998) Behav Neurosci , vol.112 , pp. 1475-1485
    • Szechtman, H.1    Sulis, W.2    Eilam, D.3
  • 48
    • 0035789196 scopus 로고    scopus 로고
    • Compulsive checking behavior of quinpirole-sensitized rats as an animal model of obsessive-compulsive disorder (OCD): Form and control
    • Szechtman H, Eckert MJ, Tse WS, Boersma JT, Bonura CA, McClelland JZ, et al. (2001). Compulsive checking behavior of quinpirole-sensitized rats as an animal model of obsessive-compulsive disorder (OCD): form and control. Bmc Neurosci 2:4.
    • (2001) Bmc Neurosci , vol.2 , pp. 4
    • Szechtman, H.1    Eckert, M.J.2    Tse, W.S.3    Boersma, J.T.4    Bonura, C.A.5    McClelland, J.Z.6
  • 49
    • 0030813682 scopus 로고    scopus 로고
    • Locomotor sensitization to quinpirole: Environment-modulated increase in efficacy and context-dependent increase in potency
    • Szumlinski KK, Allan M, Talangbayan H, Tracey A, Szechtman H (1997). Locomotor sensitization to quinpirole: environment-modulated increase in efficacy and context-dependent increase in potency. Psychopharmacology (Berl) 134:193-200.
    • (1997) Psychopharmacology (Berl , vol.134 , pp. 193-200
    • Szumlinski, K.K.1    Allan, M.2    Talangbayan, H.3    Tracey, A.4    Szechtman, H.5
  • 50
    • 0037081498 scopus 로고    scopus 로고
    • Effect of nicotine on quinpirole-induced checking behavior in rats: Implications for obsessive-compulsive disorder
    • Tizabi Y, Louis VA, Taylor CT, Waxman D, Culver KE, Szechtman H (2002). Effect of nicotine on quinpirole-induced checking behavior in rats: implications for obsessive-compulsive disorder. Biol Psychiatry 51:164-171.
    • (2002) Biol Psychiatry , vol.51 , pp. 164-171
    • Tizabi, Y.1    Louis, V.A.2    Taylor, C.T.3    Waxman, D.4    Culver, K.E.5    Szechtman, H.6
  • 51
    • 84857457297 scopus 로고    scopus 로고
    • Serotonin 2A receptor, serotonin transporter and dopamine transporter alterations in dogs with compulsive behaviour as a promising model for human obsessive-compulsive disorder
    • Vermeire S, Audenaert K, De Meester R, Vandermeulen E, Waelbers T, De Spiegeleer B, et al. (2012). Serotonin 2A receptor, serotonin transporter and dopamine transporter alterations in dogs with compulsive behaviour as a promising model for human obsessive-compulsive disorder. Psychiat Res-Neuroimag 201:78-87.
    • (2012) Psychiat Res-Neuroimag , vol.201 , pp. 78-87
    • Vermeire, S.1    Audenaert, K.2    De Meester, R.3    Vandermeulen, E.4    Waelbers, T.5    De Spiegeleer, B.6
  • 52
    • 84913603549 scopus 로고    scopus 로고
    • Neurobiology of obsessive-compulsive disorder: Serotonin and beyond
    • Westenberg HG, Fineberg NA, Denys D (2007). Neurobiology of obsessive-compulsive disorder: serotonin and beyond. CNS Spectr 12 (Suppl 3):14-27.
    • (2007) CNS Spectr , vol.12 , Issue.SUPPL. 3 , pp. 14-27
    • Westenberg, H.G.1    Fineberg, N.A.2    Denys, D.3
  • 53
    • 33745329470 scopus 로고    scopus 로고
    • The exploratory behavior of rats in an open environment optimizes security
    • Whishaw IQ, Gharbawie OA, Clark BJ, Lehmann H (2006). The exploratory behavior of rats in an open environment optimizes security. Behav Brain Res 171:230-239.
    • (2006) Behav Brain Res , vol.171 , pp. 230-239
    • Whishaw, I.Q.1    Gharbawie, O.A.2    Clark, B.J.3    Lehmann, H.4
  • 54
    • 42049116546 scopus 로고    scopus 로고
    • The role of the subthalamic nucleus in 'compulsive' behavior in rats
    • Winter C, Flash S, Klavir O, Klein J, Sohr R, Joel D (2008). The role of the subthalamic nucleus in 'compulsive' behavior in rats. Eur J Neurosci 27:1902-1911.
    • (2008) Eur J Neurosci , vol.27 , pp. 1902-1911
    • Winter, C.1    Flash, S.2    Klavir, O.3    Klein, J.4    Sohr, R.5    Joel, D.6
  • 55
    • 0000645386 scopus 로고
    • Obsessive compulsive disorder-is it a basal ganglia dysfunction?
    • Rapoport J, editor Washington, DC: American Psychiatric Press
    • Wise S, Rapoport JL (1989). Obsessive compulsive disorder-is it a basal ganglia dysfunction? In: Rapoport J, editor. Obsessive compulsive disorder in children and adolescence. Washington, DC: American Psychiatric Press; pp. 327-344.
    • (1989) Obsessive Compulsive Disorder in Children and Adolescence , pp. 327-344
    • Wise, S.1    Rapoport, J.L.2
  • 56
    • 23844548906 scopus 로고    scopus 로고
    • Motivation, time course, and heterogeneity in obsessive-compulsive disorder: Response to Taylor McKay and Abramowitz
    • Woody EZ, Szechtman H (2005). Motivation, time course, and heterogeneity in obsessive-compulsive disorder: response to Taylor, McKay, and Abramowitz. Psychol Rev 112:658-661.
    • (2005) Psychol Rev , vol.112 , pp. 658-661
    • Woody, E.Z.1    Szechtman, H.2
  • 57
    • 79951576408 scopus 로고    scopus 로고
    • Adaptation to potential threat: The evolution, neurobiology, and psychopathology of the security motivation system
    • Woody EZ, Szechtman H (2011). Adaptation to potential threat: the evolution, neurobiology, and psychopathology of the security motivation system. Neurosci Biobehav Rev 35:1019-1033.
    • (2011) Neurosci Biobehav Rev , vol.35 , pp. 1019-1033
    • Woody, E.Z.1    Szechtman, H.2
  • 58
    • 0026355203 scopus 로고
    • Spontaneous alternation behavior: An animal model for obsessive-compulsive disorder?
    • Yadin E, Friedman E, Bridger WH (1991). Spontaneous alternation behavior: an animal model for obsessive-compulsive disorder? Pharmacol Biochem Behav 40:311-315.
    • (1991) Pharmacol Biochem Behav , vol.40 , pp. 311-315
    • Yadin, E.1    Friedman, E.2    Bridger, W.H.3
  • 59
    • 34147120311 scopus 로고    scopus 로고
    • Modulation of quinpirole-induced compulsive-like behavior in rats by environmental changes: Implications for OCD rituals and for exploration and navigation
    • Zadicario P, Ronen S, Eilam D (2007). Modulation of quinpirole-induced compulsive-like behavior in rats by environmental changes: implications for OCD rituals and for exploration and navigation. Bmc Neurosci 8:23.
    • (2007) Bmc Neurosci , vol.8 , pp. 23
    • Zadicario, P.1    Ronen, S.2    Eilam, D.3


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