Long-term outcomes of concomitant chemoradiotherapy incorporating high-dose-rate brachytherapy to treat locally advanced cervical cancer

Tumori

Volumn 98, Issue 5, 2012, Pages 615-621

  Lee, Hyun Jin ^a   Kim, Young Seok ^a   Shin, Seong Soo ^a   Nam, Joo Hyun ^a   Kim, Young Tak ^a   Han, Seungbong ^a   Choi, Eun Kyung ^a  

^a University of Ulsan   (South Korea)

Author keywords

Chemoradiotherapy; High dose rate brachytherapy; Uterine cervical cancer

Indexed keywords

CARBOPLATIN; CISPLATIN; FLUOROURACIL; IFOSFAMIDE; PACLITAXEL;

ADULT; ADVANCED CANCER; AGED; ARTICLE; BLOOD TOXICITY; BRACHYTHERAPY; CANCER CONTROL; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CHEMORADIOTHERAPY; DISEASE FREE SURVIVAL; DYSURIA; EXTERNAL BEAM RADIOTHERAPY; FEMALE; FOLLOW UP; GASTROINTESTINAL TOXICITY; HEMATURIA; HIGH DOSE RATE INTRACAVITARY BRACHYTHERAPY; HUMAN; INTESTINE OBSTRUCTION; LYMPHADENOPATHY; MAJOR CLINICAL STUDY; MULTIPLE CYCLE TREATMENT; OVERALL SURVIVAL; PARAAORTIC LYMPH NODE; PARAMETRIAL DISEASE; PELVIC LYMPHADENOPATHY; PROCTITIS; RADIATION DOSE; RECTOVAGINAL FISTULA; SIDE EFFECT; SURVIVAL RATE; TUMOR VOLUME; URETER OBSTRUCTION; URINARY FREQUENCY; URINARY URGENCY; UROGENITAL TRACT DISEASE; UTERINE CERVIX CANCER; UTERINE CERVIX DISEASE;

ADULT; AGED; ANALYSIS OF VARIANCE; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BRACHYTHERAPY; CHEMORADIOTHERAPY; CISPLATIN; DISEASE-FREE SURVIVAL; DRUG ADMINISTRATION SCHEDULE; FEMALE; FLUOROURACIL; HUMANS; KAPLAN-MEIER ESTIMATE; MIDDLE AGED; NEOPLASM STAGING; PACLITAXEL; RADIOTHERAPY DOSAGE; RETROSPECTIVE STUDIES; TIME FACTORS; TREATMENT OUTCOME; UTERINE CERVICAL NEOPLASMS;

EID: 84872071105     PISSN: 03008916     EISSN: 20382529     Source Type: Journal    
DOI: 10.1700/1190.13203     Document Type: Article

References (27)

1. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D: Global cancer statistics. CA Cancer J Clin, 61: 69-90, 2011.
2. Kim YT: Current status of cervical cancer and HPV infection in Korea. J Gynecol Oncol, 20: 1-7, 2009.
3. Keys HM, Bundy BN, Stehman FB, Muderspach LI, Chafe WE, Suggs CL 3rd, Walker JL, Gersell D: Cisplatin, radiation, and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage IB cervical carcinoma. N Engl J Med, 340: 1154-1161, 1999.
4. Morris M, Eifel PJ, Lu J, Grigsby PW, Levenback C, Stevens RE, Rotman M, Gershenson DM, Mutch DG: Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer. N Engl J Med, 340: 1137-1143, 1999.
5. Rose PG, Bundy BN, Watkins EB, Thigpen JT, Deppe G, Maiman MA, Clarke-Pearson DL, Insalaco S: Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer. N Engl J Med, 340: 1144-1153, 1999.
6. Whitney CW, Sause W, Bundy BN, Malfetano JH, Hannigan EV, Fowler WC Jr, Clarke-Pearson DL, Liao SY: Randomized comparison of fluorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stage IIB-IVA carcinoma of the cervix with negative para-aortic lymph nodes: a Gynecologic Oncology Group and Southwest Oncology Group study. J Clin Oncol, 17: 1339-1348, 1999.
7. Peters WA, 3rd, Liu PY, Barrett RJ 2nd, Stock RJ, Monk BJ, Berek JS, Souhami L, Grigsby P, Gordon W Jr, Alberts DS: Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix. J Clin Oncol, 18: 1606-1613, 2000.
8. Pearcey R, Brundage M, Drouin P, Jeffrey J, Johnston D, Lukka H, MacLean G, Souhami L, Stuart G, Tu D: Phase III trial comparing radical radiotherapy with and without cisplatin chemotherapy in patients with advanced squamous cell cancer of the cervix. J Clin Oncol, 20: 966-972, 2002.
9. Tseng CJ, Chang CT, Lai CH, Soong YK, Hong JH, Tang SG, Hsueh S: A randomized trial of concurrent chemoradiotherapy versus radiotherapy in advanced carcinoma of the uterine cervix. Gynecol Oncol, 66: 52-58, 1997.
10. Nag S, Erickson B, Thomadsen B, Orton C, Demanes JD, Petereit D: The American Brachytherapy Society recommendations for high-dose-rate brachytherapy for carcinoma of the cervix. Int J Radiat Oncol Biol Phys, 48: 201-211, 2000.
11. Hareyama M, Sakata K, Oouchi A, Nagakura H, Shido M, Someya M, Koito K: High-dose-rate versus low-dose-rate intracavitary therapy for carcinoma of the uterine cervix: a randomized trial. Cancer, 94: 117-124, 2002.
12. Lertsanguansinchai P, Lertbutsayanukul C, Shotelersuk K, Khorprasert C, Rojpornpradit P, Chottetanaprasith T, Srisuthep A, Suriyapee S, Jumpangern C, Tresukosol D, Charoonsantikul C: Phase III randomized trial comparing LDR and HDR brachytherapy in treatment of cervical carcinoma. Int J Radiat Oncol Biol Phys, 59: 1424-1431, 2004.
13. Teshima T, Inoue T, Ikeda H, Miyata Y, Nishiyama K, Inoue T, Murayama S, Yamasaki H, Kozuka T: High-dose rate and low-dose rate intracavitary therapy for carcinoma of the uterine cervix. Final results of Osaka University Hospital. Cancer, 72: 2409-2414, 1993.
14. Atahan IL, Onal C, Ozyar E, Yiliz F, Selek U, Kose F: Longterm outcome and prognostic factors in patients with cervical carcinoma: a retrospective study. Int J Gynecol Cancer, 17: 833-842, 2007.
15. Chen SW, Liang JA, Hung YC, Yeh LS, Chang WC, Lin WC, Yang SN, Lin FJ: Concurrent weekly cisplatin plus external beam radiotherapy and high-dose rate brachytherapy for advanced cervical cancer: a control cohort comparison with radiation alone on treatment outcome and complications. Int J Radiat Oncol Biol Phys, 66: 1370-1377, 2006.
16. Novetsky AP, Einstein MH, Goldberg GL, Hailpern SM, Landau E, Fields AL, Mutyala S, Kalnicki S, Garg M: Efficacy and toxicity of concomitant cisplatin with external beam pelvic radiotherapy and two high-dose-rate brachytherapy insertions for the treatment of locally advanced cervical cancer. Gynecol Oncol, 105: 635-640, 2007.
17. Parker K, Gallop-Evans E, Hanna L, Adams M: Five years' experience treating locally advanced cervical cancer with concurrent chemoradiotherapy and high-dose-rate brachytherapy: results from a single institution. Int J Radiat Oncol Biol Phys, 74: 140-146, 2009.
18. Sakata K, Sakurai H, Suzuki Y, Katoh S, Ohno T, Toita T, Kataoka M, Tanaka E, Kaneyasu Y, Uno T, Harima Y, Nakano T, Japan Radiation Oncology Study G: Results of concomitant chemoradiation for cervical cancer using high dose rate intracavitary brachytherapy: study of JROSG (Japan Radiation Oncology Study Group). Acta Oncol, 47: 434-441, 2008.
19. Teh J, Yap SP, Tham I, Sethi VK, Chua EJ, Yeo R, Ho TH, Tay EH, Chia YN, Soh LT, Khoo-Tan HS: Concurrent chemoradiotherapy incorporating high-dose rate brachytherapy for locally advanced cervical carcinoma: survival outcomes, patterns of failure, and prognostic factors. Int J Gynecol Cancer, 20: 428-433, 2010.
20. Toita T, Moromizato H, Ogawa K, Kakinohana Y, Maehama T, Kanazawa K, Murayama S: Concurrent chemoradiotherapy using high-dose-rate intracavitary brachytherapy for uterine cervical cancer. Gynecol Oncol, 96: 665-670, 2005.
21. Forrest JL, Ackerman I, Barbera L, Barnes EA, Davidson M, Kiss A, Thomas G: Patient outcome study of concurrent chemoradiation, external beam radiotherapy, and high-dose rate brachytherapy in locally advanced carcinoma of the cervix. Int J Gynecol Cancer, 20: 1074-1078, 2010.
22. Kim YS, Kim JH, Ahn SD, Lee SW, Shin SS, Nam JH, Kim YT, Kim YM, Kim JH, Choi EK: High-dose extended-field irradiation and high-dose-rate brachytherapy with concurrent chemotherapy for cervical cancer with positive para-aortic lymph nodes. Int J Radiat Oncol Biol Phys, 74: 1522-1528, 2009.
23. Kim YS, Shin SS, Nam JH, Kim YT, Kim YM, Kim JH, Choi EK: Prospective randomized comparison of monthly fluorouracil and cisplatin versus weekly cisplatin concurrent with pelvic radiotherapy and high-dose rate brachytherapy for locally advanced cervical cancer. Gynecol Oncol, 108: 195-200, 2008.
24. ICRU: Prescribing, recording, and reporting photon beam therapy. ICRU Report 38. Bethesda, Maryland. International Commission on Radiation Units and Measurements, 1985.
25. Potter R, Dimopoulos J, Georg P, Lang S, Waldhausl C, Wachter-Gerstner N, Weitmann H, Reinthaller A, Knocke TH, Wachter S, Kirisits C: Clinical impact of MRI assisted dose volume adaptation and dose escalation in brachytherapy of locally advanced cervix cancer. Radiother Oncol, 83: 148-155, 2007.
26. Perez CA, Grigsby PW, Castro-Vita H, Lockett MA: Carcinoma of the uterine cervix. I. Impact of prolongation of overall treatment time and timing of brachytherapy on outcome of radiation therapy. Int J Radiat Oncol Biol Phys, 32: 1275-1288, 1995.
27. Petereit DG, Sarkaria JN, Chappell R, Fowler JF, Hartmann TJ, Kinsella TJ, Stitt JA, Thomadsen BR, Buchler DA: The adverse effect of treatment prolongation in cervical carcinoma. Int J Radiat Oncol Biol Phys, 32: 1301-1307, 1995.