-
1
-
-
79952681720
-
Sirolimus and its analogs and its effects on vascular diseases
-
Adelman S. Sirolimus and its analogs and its effects on vascular diseases. Curr Pharm Des 2010; 16: 4002.
-
(2010)
Curr Pharm des
, vol.16
, pp. 4002
-
-
Adelman, S.1
-
2
-
-
0033552883
-
AtherosclerosisVan inflammatory disease
-
Ross R. AtherosclerosisVan inflammatory disease. N Engl J Med 1999; 340: 115.
-
(1999)
N Engl J Med
, vol.340
, pp. 115
-
-
Ross, R.1
-
3
-
-
0037180771
-
Inflammation in atherosclerosis
-
Libby P. Inflammation in atherosclerosis. Nature 2002; 420: 868.
-
(2002)
Nature
, vol.420
, pp. 868
-
-
Libby, P.1
-
4
-
-
0032105481
-
Rapamune (RAPA, rapamycin, sirolimus): Mechanism of action of immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression
-
Sehgal SN. Rapamune (RAPA, rapamycin, sirolimus): mechanism of action of immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression. Clin Biochem 1998; 31: 335.
-
(1998)
Clin Biochem
, vol.31
, pp. 335
-
-
Sehgal, S.N.1
-
5
-
-
77952595127
-
Sirolimus inhibits endogenous cholesterol synthesis induced by inflammatory stress in human vascular smooth muscle cells
-
Ma KL, Varghese Z, Ku Y, et al. Sirolimus inhibits endogenous cholesterol synthesis induced by inflammatory stress in human vascular smooth muscle cells. Am J Physiol Heart Circ Physiol 2010; 298: H1646.
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.298
-
-
Ma, K.L.1
Varghese, Z.2
Ku, Y.3
-
6
-
-
34447530621
-
Anti-atherosclerotic effects of sirolimus on human vascular smooth muscles cells
-
Ma KL, Ruan XZ, Powis SH, et al. Anti-atherosclerotic effects of sirolimus on human vascular smooth muscles cells. Am J Physiol Heart Circ Physiol 2007; 292: H2721.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.292
-
-
Ma, K.L.1
Ruan, X.Z.2
Powis, S.H.3
-
7
-
-
0038585135
-
Protective effect of the immunosuppressant sirolimus against aortic atherosclerosis in apo E-deficient mice
-
Elloso MM, Azrolan N, Sehgal SN, et al. Protective effect of the immunosuppressant sirolimus against aortic atherosclerosis in apo E-deficient mice. Am J Transplant 2003; 3: 562.
-
(2003)
Am J Transplant
, vol.3
, pp. 562
-
-
Elloso, M.M.1
Azrolan, N.2
Sehgal, S.N.3
-
8
-
-
10944223355
-
Cardiovascular risk profile in patients treated with sirolimus after renal transplantation
-
Morales JM. Cardiovascular risk profile in patients treated with sirolimus after renal transplantation. Kidney Int Suppl 2005; 93: S69.
-
(2005)
Kidney Int Suppl
, vol.93
-
-
Morales, J.M.1
-
9
-
-
0036664390
-
Effects of sirolimus on lipids in renal allograft recipients: An analysis using the Framingham risk model
-
Blum CB. Effects of sirolimus on lipids in renal allograft recipients: an analysis using the Framingham risk model. Am J Transplant 2002; 2: 551.
-
(2002)
Am J Transplant
, vol.2
, pp. 551
-
-
Blum, C.B.1
-
10
-
-
0034789734
-
Risk factors for management of post-transplantation cardiovascular disease
-
Fellstrom B. Risk factors for management of post-transplantation cardiovascular disease. Biodrugs 2001; 15: 261.
-
(2001)
Biodrugs
, vol.15
, pp. 261
-
-
Fellstrom, B.1
-
12
-
-
0031738068
-
Controlling the epidemic of cardiovascular disease in chronic renal disease what do we know? What do we need to learn? Where do we go from here?
-
Levey AS, Beto JA, Coronado BE, et al. Controlling the epidemic of cardiovascular disease in chronic renal disease: what do we know? What do we need to learn? Where do we go from here? Am J Kidney Dis 1998; 32: 853.
-
(1998)
Am J Kidney Dis
, vol.32
, pp. 853
-
-
Levey, A.S.1
Beto, J.A.2
Coronado, B.E.3
-
14
-
-
66949167065
-
Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptor
-
Zhao L, Ding T, Cyrus T, et al. Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptor. Br J Pharmacol 2009; 156: 774.
-
(2009)
Br J Pharmacol
, vol.156
, pp. 774
-
-
Zhao, L.1
Ding, T.2
Cyrus, T.3
-
15
-
-
0029845013
-
Rapamycin inhibits vascular smooth muscle cell migration
-
Poon M, Marx SO, Gallo R, et al. Rapamycin inhibits vascular smooth muscle cell migration. J Clin Invest 2005; 98: 2277.
-
(2005)
J Clin Invest
, vol.98
, pp. 2277
-
-
Poon, M.1
Marx, S.O.2
Gallo, R.3
-
16
-
-
0347985757
-
Rapamycin attenuates atherosclerosis induced by dietary cholesterol in apolipoprotein-deficient mice through a p27Kip1-independent pathway
-
Castro C, Campistol JM, Sancho D, et al. Rapamycin attenuates atherosclerosis induced by dietary cholesterol in apolipoprotein-deficient mice through a p27Kip1-independent pathway. Atherosclerosis 2004; 172: 31.
-
(2004)
Atherosclerosis
, vol.172
, pp. 31
-
-
Castro, C.1
Campistol, J.M.2
Sancho, D.3
-
17
-
-
26044448312
-
Rapamycin attenuates atherosclerotic plaque progression in apolipoprotein e knockout mice: Inhibitory effect on monocyte chemotaxis
-
Pakala R, Stabile E, Jang GJ, et al. Rapamycin attenuates atherosclerotic plaque progression in apolipoprotein E knockout mice: inhibitory effect on monocyte chemotaxis. J Cardiovasc Pharm2005; 46: 481.
-
J Cardiovasc Pharm2005
, vol.46
, pp. 481
-
-
Pakala, R.1
Stabile, E.2
Jang, G.J.3
-
18
-
-
33846177854
-
The pharmacodynamics effects of sirolimus and sirolimus-calcineurin inhibitor combinations on macrophage scavenger and nuclear hormone receptors
-
Mathis AS, Jin S, Friedman GS, et al. The pharmacodynamics effects of sirolimus and sirolimus-calcineurin inhibitor combinations on macrophage scavenger and nuclear hormone receptors. J Pharm Sci 2007; 96: 209.
-
(2007)
J Pharm Sci
, vol.96
, pp. 209
-
-
Mathis, A.S.1
Jin, S.2
Friedman, G.S.3
-
19
-
-
36048952425
-
Risk factors for atherosclerosis and the development of preatherosclerotic intimal hyperplasia
-
Cizek SM, Bedri S, Talusan P, et al. Risk factors for atherosclerosis and the development of preatherosclerotic intimal hyperplasia. Cardiovasc Pathol 2007; 16: 344.
-
(2007)
Cardiovasc Pathol
, vol.16
, pp. 344
-
-
Cizek, S.M.1
Bedri, S.2
Talusan, P.3
-
20
-
-
1442325390
-
The mTOR/p70/S6k1 pathway regulates vascular smooth muscle cell differentiation
-
Martin KA, Rzucidlo EM, Merenick BL, et al. The mTOR/p70/S6k1 pathway regulates vascular smooth muscle cell differentiation. Am J Physiol Cell Physiol 2004; 286: C507.
-
(2004)
Am J Physiol Cell Physiol
, vol.286
-
-
Martin, K.A.1
Rzucidlo, E.M.2
Merenick, B.L.3
-
21
-
-
0028821333
-
Rapamycin (sirolimus) inhibits vascular smooth muscle DNA synthesis in vitro and suppresses narrowing in arterial allografts in balloon-injured carotid arteries: Evidence that rapamycin antagonizes growth factor action on immune and non-immune cells
-
Morris RE, Cao W, Huang X, et al. Rapamycin (sirolimus) inhibits vascular smooth muscle DNA synthesis in vitro and suppresses narrowing in arterial allografts in balloon-injured carotid arteries: evidence that rapamycin antagonizes growth factor action on immune and non-immune cells. Transplant Proc 1995; 27: 430.
-
(1995)
Transplant Proc
, vol.27
, pp. 430
-
-
Morris, R.E.1
Cao, W.2
Huang, X.3
-
22
-
-
0034855964
-
The growth suppressor p27 (Kip1) protects against diet-induced atherosclerosis
-
Diez-Juan A, Andres V. The growth suppressor p27 (Kip1) protects against diet-induced atherosclerosis. FASEB J 2001; 11: 1989.
-
(2001)
FASEB J
, vol.11
, pp. 1989
-
-
Diez-Juan, A.1
Andres, V.2
-
23
-
-
0027301130
-
Rapamycin inhibits arterial intimal thickening caused by both alloimmune and mechanical injury: Its effects on cellular, growth factor, and cytokine responses in injured vessels
-
Gregory CR, Huie P, Billingham ME, et al. Rapamycin inhibits arterial intimal thickening caused by both alloimmune and mechanical injury: its effects on cellular, growth factor, and cytokine responses in injured vessels. Transplantation 1993; 55: 1409.
-
(1993)
Transplantation
, vol.55
, pp. 1409
-
-
Gregory, C.R.1
Huie, P.2
Billingham, M.E.3
-
24
-
-
0033044882
-
Neointimal formation after balloon-induced vascular injury in Yucatan minipigs is reduced by oral rapamycin
-
Burke SE, Lubbers NL, Chen YW, et al. Neointimal formation after balloon-induced vascular injury in Yucatan minipigs is reduced by oral rapamycin. J Cardiovasc Pharmacol 1999; 33: 829.
-
(1999)
J Cardiovasc Pharmacol
, vol.33
, pp. 829
-
-
Burke, S.E.1
Lubbers, N.L.2
Chen, Y.W.3
-
25
-
-
77955984827
-
Murine cytomegalovirus infection leads to increased levels of transplant arteriosclerosis in a murine aortic allograft model
-
Heim C, Abele-Ohi S, Eckl S, et al. Murine cytomegalovirus infection leads to increased levels of transplant arteriosclerosis in a murine aortic allograft model. Transplantation 2010; 90: 373.
-
(2010)
Transplantation
, vol.90
, pp. 373
-
-
Heim, C.1
Abele-Ohi, S.2
Eckl, S.3
-
26
-
-
0028341436
-
Active cytomegalovirus infection of arterial smooth muscle cells in immunocompromised rats. A clue to herpesvirus-associated atherogenesis
-
Persoons MC, Daemen MJ, Bruning JH, et al. Active cytomegalovirus infection of arterial smooth muscle cells in immunocompromised rats. A clue to herpesvirus-associated atherogenesis. Circ Res 1994; 75: 214.
-
(1994)
Circ Res
, vol.75
, pp. 214
-
-
Persoons, M.C.1
Daemen, M.J.2
Bruning, J.H.3
-
27
-
-
0029823367
-
The role of infection in restenosis and atherosclerosis: Focus on cytomegalovirus
-
Epstein SE, Speir E, Zhou YF, et al. The role of infection in restenosis and atherosclerosis: focus on cytomegalovirus. Lancet 1996; 348: 13.
-
(1996)
Lancet
, vol.348
, pp. 13
-
-
Epstein, S.E.1
Speir, E.2
Zhou, Y.F.3
-
28
-
-
0029840904
-
Association between prior cytomegalovirus infection and the risk of restenosis after coronary atherectomy
-
Zhou YF, Keon MB, Waclawiw MA, et al. Association between prior cytomegalovirus infection and the risk of restenosis after coronary atherectomy. New Engl J Med 1996; 335: 625.
-
(1996)
New Engl J Med
, vol.335
, pp. 625
-
-
Zhou, Y.F.1
Keon, M.B.2
Waclawiw, M.A.3
-
29
-
-
77951480815
-
Rapamycin-resistant mTORC1 kinase activity is required for herpesvirus replication
-
Moorman NJ, Shenk T. Rapamycin-resistant mTORC1 kinase activity is required for herpesvirus replication. J Virol 2010; 84: 5260.
-
(2010)
J Virol
, vol.84
, pp. 5260
-
-
Moorman, N.J.1
Shenk, T.2
-
30
-
-
84862290097
-
Review of cytomegalovirus infection findings with mammalian target of rapamycin inhibitorYbased immunosuppressive therapy in de novo renal transplant recipients
-
Nashan B, Gaston R, Emery V, et al. Review of cytomegalovirus infection findings with mammalian target of rapamycin inhibitorYbased immunosuppressive therapy in de novo renal transplant recipients. Transplantation 2012; 93: 1075.
-
(2012)
Transplantation
, vol.93
, pp. 1075
-
-
Nashan, B.1
Gaston, R.2
Emery, V.3
-
32
-
-
39549093148
-
General cardiovascular risk profile for use in primary care: The Framingham Heart Study
-
D'Agostino RB Sr, Vasan RS, Pencina MJ, et al. General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation 2008; 117: 743.
-
(2008)
Circulation
, vol.117
, pp. 743
-
-
D'Agostino Sr., R.B.1
Vasan, R.S.2
Pencina, M.J.3
|