Role of hyperglycemia-mediated erythrocyte redox state alteration in the development of diabetic retinopathy

Retina

Volumn 33, Issue 1, 2013, Pages 207-216

  Choudhuri, Subhadip ^a   Mandal, Lakshmi K ^b   Paine, Suman ^a   Sen, Aditi ^a   Dutta, Deep ^a   Chowdhury, Imran ^a   Mukherjee, Amrita ^a   Saha, Avijit ^a   Bhadhuri, Gautam ^b   Bhattacharya, Basudev ^a  

^a INSTITUTE OF POST GRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

^b MEDICAL COLLEGE AND HOSPITAL   (India)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE; LACTIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ADULT; ARTICLE; CONTROLLED STUDY; DIABETES CONTROL; DIABETIC PATIENT; DIABETIC RETINOPATHY; DISEASE ASSOCIATION; DISEASE COURSE; ERYTHROCYTE; FEMALE; HUMAN; HYPERGLYCEMIA; LACTATE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATION REDUCTION STATE; PROTEIN BLOOD LEVEL; RETINA CELL; SPECTROPHOTOMETRY; VITREOUS BODY;

BLOOD GLUCOSE; BLOOD PRESSURE; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 2; DIABETIC RETINOPATHY; ERYTHROCYTE MEMBRANE; ERYTHROCYTES; FEMALE; FLUORESCEIN ANGIOGRAPHY; GLUCOSE TOLERANCE TEST; GLUTATHIONE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; HYPERGLYCEMIA; LACTIC ACID; MALE; MIDDLE AGED; NAD; NADP; OXIDATION-REDUCTION; PYRUVIC ACID;

EID: 84872059978     PISSN: 0275004X     EISSN: 15392864     Source Type: Journal    
DOI: 10.1097/IAE.0b013e318256202e     Document Type: Article

References (50)

1. Frank RN. Diabetic retinopathy. N Engl J Med 2004;350: 48-58.
2. Aylward GW. Progressive changes in diabetics and their management. Eye 2005;19:1115-1118.
3. Bhavasar AR. Diabetic retinopathy: the latest in current management. Retina 2006;26(suppl 6):S71-S79.
4. Ozturk BT, Bozkurt B, Kerimoglu H, et al. Effect of serum cytokines and VEGF levels on diabetic retinopathy and macular thickness. Mol Vis 2009;15:1906-1914.
5. Abu El-Asrar AM, Struyf S, Kangave D, et al. Chemokines in proliferative diabetic retinopathy and proliferative vitreoretinopathy. Eur Cytokine Netw 2006;17:155-165.
6. Ido Y, Kilo C, Williamson Jr. Cytosolic NADH/NAD+, free radicals and vascular dysfunction in early diabetes mellitus. Diabetologia 1997;40:S115-S117.
7. Williamson JR, Chang K, Frangos M, et al. Hyperglycemic pseudohypoxia and diabetic complications. Diabetes 1993;42: 801-813.
8. Bravi MC, Pietrangeli P, Laurenti O, et al. Polyol pathway activation and glutathione redox status in non insulin dependent diabetic patients. Metabolism 1997;46:1194-1198.
9. Nyengaard JR, Ido Y, Kilo C, Williamson Jr. Interactions between hyperglycemia and hypoxia implications for diabetic retinopathy. Diabetes 2004;53:2931-2938.
10. Barron JT, Gu Land Parillo JE. Malate-aspartate shuttle, cytoplasmic NADH redox potential, and energetics in vascular smooth muscle. J Mol Cell Cardiol 1998;30:1571-1579.
11. Lin SJ, Guarente L. Nicotenamide adenine dinucleotide, a metabolic regulator of transcription, longevity and disease. Curr Opin Cell Biol 2003;15:241-246.
12. Ido Y, Chang K, Woolsey TA, Williamson Jr. NADH: sensor of blood flow need in brain, muscle, and other tissues. FASEB J 2001;15:1419-1423.
13. Reddy GB, Satyanarayana A, Balakrishna N, et al. Erythrocyte aldose reductase activity and sorbitol levels in diabetic retinopathy. Mol Vis 2008;14:593-601.
14. Dagher Z, Park YS, Asnaghi V, et al. Studies of rat and human retinas predict a role for the polyol pathway in human diabetic retinopathy. Diabetes 2004;53:2404-2411.
15. Asnaghi V, Gerhardinger C, Hoen T, et al. A role for the polyol pathway in the early neuroretinal apoptosis and glial changes induced by diabetes in rat. Diabetes 2003;52: 506-511.
16. Barron JT, Gu L, Parrillo JE. NADH / NAD redox state of cytoplasmic glycolytic compartments in vascular smooth muscle. Am J Physiol Heart Circ Physiol 2000;279: H2872-H2878.
17. Maria K, Vanden E, Nyeengaard J, et al. Elevated glucose levels increase retinal glycolysis and sorbitol pathway metabolism. Invest Ophthalmol Vis Sci 1995;36:1675-1685.
18. Lorenzi M. The polyol pathway as a mechanism for diabetic retinopathy: attractive, elusive and resilient. Exp Diabetes Res 2007;2007:1-10.
19. Hwang JH, Kim DW, Jo EJ, et al. Pharmacological stimulation of NADH oxidation ameliorates obesity and related phenotypes in mice. Diabetes 2009;58:965-974.
20. Haskins K, Bradley B, Powers K. Oxidative stress in type 1 diabetes. Ann N Y Acad Sci 2003;1005:43-54.
21. Kowluru RA. Diabetic retinopathy: mitochondrial dysfunction and retinal capillary cell death. Antioxid Redox Signal 2005;7: 1581-1587.
22. World Health Organization. Definition and Diagnosis of Diabetes Mellitus and Intermediate Hyperglycemia: Report of a WHO/IDF Consultation: Diagnosis and Classification of Diabetes Mellitus. Geneva, Switzerland: World Health Organization; 2006.
23. Liao JC, Rountree M, Good R, et al. Determination of D-sorbitol in human erythrocytes by an improved enzymatic method with fluorometric detection. Clin Chem 1988;34:2327-2330.
24. Travis SF, Morrison AD, Clements RS, et al. Metabolic alterations in the human erythrocyte produced by increase in glucose concentration: the role of the polyol pathway. J Clin Invest 1971;50:2104-2112.
25. Izuta H, Matsunaga N, Shimazawa M, et al. Proliferative diabetic retinopathy and relations among antioxidant activity, oxidative stress, and VEGF in the vitreous body. Mol Vis 2010;16:130-136.
26. Orlidge A, D'Amore PA. Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells. J Cell Biol 1987;105:1455-1462.
27. Murphy RP. Management of diabetic retinopathy. Am Fam Physician 1995;51:785-796.
28. Rema M, Pradeepa R. Diabetic retinopathy: an Indian perspective. Indian J Med Res 2007;125:297-310.
29. Pfister F, Feng Y, Hagen FV, et al. A novel mechanism of pericyte loss in experimental diabetic retinopathy. Diabetes 2008;57:2495-2502.
30. Mari M, Colell A, Morales A, et al. Redox control of liver function in health and disease. Antioxid Redox Signal 2010; 12:1295-1328.
31. Circu ML, Aw TY. Glutathione and apoptosis. Free Radic Res 2008;42:689-706.
32. Tian WN, Stanton RC, Leigh D, et al. Importance of glucose- 6-phosphatedehydrogenase activity in cell death. Am J Physiol Lung Cell Mol Physiol 2010;299:L513-L522.
33. Jones DP, Carlson JL, Mody VC, et al. Redox state of glutathione in human plasma. Free Radic Biol Med 2000;28: 625-635.
34. Chung SS, Ho EC, Lam KS, Chung SK. Contribution of polyol pathway to diabetes-induced oxidative stress. J Am Soc Nephrol 2003;14:S233-S236.
35. Xu Y, Zhang Z, Hu J, et al. Glucose-6-phosphate dehydrogenase- deficient mice have increased renal oxidative stress and increased albuminuria. FASEB J 2010;24:609-616.
36. Maritim AC, Sanders RA, Watkins JB. Diabetes, oxidative stress, and antioxidants: a review. J Biochem Mol Toxicol 2003:17;24-38.
37. Pennathu S, Ido Y, Heller JI, et al. Reactive carbonyls and polyunsaturated fatty acids produce a hydroxyl radical-like species. J Biol Chem 2005;280:22706-22714.
38. Ciuchi E, Odetti P, Prando R. Relation between glutathione and sorbitol concentrations in erythrocytes from diabetic patients. Metabolism 1996;45:611-613.
39. Ido Y, Chang K, Williamson Jr. NADH augments blood flow in physiologically activated retina and visual cortex. Proc Natl Acad Sci U S A 2004;101:653-658.
40. Easlon E, Tsang F, Skinner C, et al. The malate-aspartate NADH shuttle components are novel metabolic longevity regulators required for calorie restriction-mediated life span extension in yeast. Genes Dev 2008;22:931-944.
41. Aiello LP. The potential role of PKC b in diabetic retinopathy and macular edema. Surv Ophthalmol 2002;47:263-269.
42. Yamagishi S, Takeuchi M. Inhibition of protein kinase C might be harmful to diabetic retinopathy. Med Hypotheses 2004;63: 135-137.
43. Guzik TJ, West NE, Black E. Vascular superoxide production by NAD(P)H oxidase association with endothelial dysfunction and clinical risk factors. Circ Res 2000;86:e85-e90.
44. Williamson JR, Ido Y. The Vascular Cellular Consequence of Hyperglycemia, in Diabetic Angiopathy. New York, NY: Arnold Oxford University Press; 1999:161-185.
45. Trudeau K, Molina JA, Roy S. High glucose induces mitochondrial morphology and metabolic changes in retinal pericytes. Invest Ophthalmol Vis Sci 2011;52:8657-8664.
46. Zhong Q, Kowluru RA. Diabetic retinopathy and damage to mitochondrial structure and transport machinery. Invest Ophthalmol Vis Sci 2011;52:8739-8746.
47. Minetti M, Agati L, Malorni W. The microenvironment can shift erythrocytes from a friendly to a harmful behavior: pathogenic implications for vascular diseases. Cardiovasc Res 2007;75:21-28.
48. Michael J, MacDonald A, Frank WR, et al. Stimulation of insulin release by glyceraldehyde may not be similar to glucose. Arch Biochem Biophys 2006;447:118-126.
49. Salceda R, Vilchis C, Coffe V, Hernández-Muñoz R. Changes in the redox state in the retina and brain during the onset of diabetes in rats. Neurochem Res 1998;23:893-897.
50. Li Q, Hwang CY, Ananthakrishnan R, et al. Polyol pathway and modulation of ischemia-reperfusion injury in type 2 diabetic BBZ rat hearts. Cardiovasc Diabetol 2008;7:33.