Radio-protective effect of catalpol in cultured cells and mice

Journal of Radiation Research

Volumn 54, Issue 1, 2013, Pages 76-82

  Chen, Chengjie ^a,b,c   Chen, Zhe ^a   Xu, Fang ^c   Zhu, Chao ^c   Fang, Fanfu ^a   Shu, Shi ^a   Li, Min ^b   Ling, Changquan ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c Aviation Medical Evaluation and Training Center of Airforce in Hangzhou   (China)

Author keywords

apoptosis; catalpol; radioprotection; reactive oxygen species

Indexed keywords

IONIZING RADIATION; MAMMALS; OXYGEN; RADIATION SHIELDING;

BIOACTIVE COMPONENTS; CATALPOL; CELL APOPTOSIS; CULTURED CELL; DNA DAMAGES; HUMAN LYMPHOCYTES; PROTECTIVE EFFECTS; RADIATION-INDUCED; RADIOPROTECTION; REACTIVE OXYGEN SPECIES;

CELL DEATH;

MUS; REHMANNIA;

EID: 84872050733     PISSN: 04493060     EISSN: 13499157     Source Type: Journal    
DOI: 10.1093/jrr/rrs080     Document Type: Article

References (36)

1. Dubner D, Gisone P, Jaitovich I et al. Free radicals production and estimation of oxidative stress related to gamma irradiation. Biol Race Elem Res 1995;47:265-70.
2. Cadet J, Bellon S, Douki T et al. Radiation-induced DNA damage: Formation, measurement, and biochemical features. J Environ Pathol Toxicol Oncol 2004;23:33-43.
3. Ogawa Y, Kobayashi T, Nishioka A et al. Radiation-induced reactive oxygen species (ROS) formation prior to oxidative DNA damage in human peripheral T cells. Int J Mol Med 2003;11:149-52.
4. Olive P-L. The role of DNA single and double strand breaks in cell killing by ionizing radiation. Radiat Res 1998;150:42-51.
5. Ramachandran A, Madesh M, Balasubramanian K-A. Apoptosis in the intestinal epithelium: Its relevance in normal and pathophysiological conditions. J Gastroenterol Hepatol 2000;15:109-20.
6. Potten C-S. Extreme sensitivity of some intestinal crypt cells to X and gamma irradiation. Nature 1977;269:518-21.
7. Dainiak N. Hematologic consequences of exposure to ionizing radiation. Exp Hematol 2002;30:513-28.
8. Weiss J-F, Landauer M-R. Protection against ionizing radiation by antioxidant nutrients and phytochemicals. Toxicology 2003;189:1-20.
9. Wen X-Y, Wang L, Tian Y-P. Protective effect of Sisheng Decoction on radiation-induced injury of mice. Acad J PLA post Med School 2010;9:921-3.
10. Zhang S-F, Chen Z, Li B et al. Effects of Sisheng Decoction on spontaneous activity and serum concentration of malondialdehyde in mice with yin deficiency syndrome. J Chin Integra Med 2008;10:1029-33.
11. Chun R-L, Zhou Z, Zhu D et al. Protective effect of paeoniflorin on irradiation-induced cell damage involved in modulation of reactive oxygen species and the mitogen-activated protein kinases. IJBCB 2007;39:426-38.
12. Sang G-K, Seon Y-N, Choon W-K. In vivo radioprotective effects of oltipraz in γ-irradiated mice. Biochem Pharmacol 1998;55:1585-90.
13. Chiu C-J, McArdle A-H, Brown R et al. Intestinal mucosal lesion in low-flow states. I. A morphological, hemodynamic, and metabolic reappraisal. Arch Surg 1970;101:478-83.
14. Kakkar P, Das B, Viswanathan P-N. A modified spectrophoto-Metric assay of superoxide dismutase (SOD). Indian J Biochem Biophys 1984;21:130-2.
15. Ellman G-L. Tissue sulfhydryl groups. Arch Biochem Biophys 1959;82:70-7.
16. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979;95:351-8.
17. Nakae D, Kobayashi Y, Akai H et al. Involvement of 8-Hydrox-Yguanine formation in the initiation of rat liver carcinogenesis by low dose levels of N-nitrosodiethylamine. Cancer Res 1997;57:1281-7.
18. Victoria V-B, Torres M-C, Boix L et al. α-Tocopherol, MDA-HNE and 8-OHdG levels in liver and heart mitochondria of adriamycin-treated rats fed with alcohol-free beer. Toxicology 2008;249:97-101.
19. Inoue T, Hayashi M, Takayanagi K et al. Oxidative DNA damage is induced by chronic cigarette smoking, but repaired by abstention. J Health Sci 2003;51:169-172.
20. Toyokuni S, Tanaka T, Hattori Y et al. Quantitative immunohistochemical determination of 8-Hydroxy-2deoxyguanosine by a monoclonal antibody N45.1: Its application to ferric nitrilotriacetate-induced renal carcinogenesis model. Lab Invest 1997;76:365-74.
21. Pungitore C-R, León L-G, García C et al. Novel antiproliferative analogs of the Taq DNA polymerase inhibitor catalpol. Bioorg Med Chem Lett 2007;17:1332-5.
22. Kim H-M, An C-S, Jung K-Y et al. Rehmannia glutinosa inhibits tumour necrosis factor-alpha and interleukin-1 secretion from mouse astrocytes. Pharmacol Res 1999;40: 171-6.
23. Bi J, Jiang B, Liu J-H et al. Protective effects of catalpol against H2O2-induced oxidative stress in astrocytes primary cultures. Neurosci Lett 2008;442:224-7.
24. Mao Y-R, Jiang L, Duan Y-L et al. Efficacy of catalpol as protectant against oxidative stress and mitochondrial dysfunction on rotenone-induced toxicity in mice brain. Environ Toxicol Pharmacol 2007;23:314-18.
25. Zhang X-L, Zhang A, Jiang B et al. Further pharmacological evidence of the neuroprotective effect of catalpol from Rehmannia glutinosa. Phytomedicine 2008;15:484-90.
26. Jiang B, Liu J-H, Bao Y-M et al. Catalpol inhibits apoptosis in hydrogen peroxide-induced PC12 cells by preventing cytochrome c release and inactivating of caspase cascade. Toxicon 2004;43:53-9.
27. Li D-Q, Bao Y-M, Li Y et al. Catalpol modulates the expressions of Bcl-2 and Bax and attenuates apoptosis in gerbils after ischemic injury. Brain Res 2006;1115:179-85.
28. Kalpana K-B, Devipriya N, Srinivasan M. Investigation of the radioprotective efficacy of hesperidin against gamma radiation induced cellular damage in cultured human peripheral blood lymphocytes. Mutat Res 2009;676:54-61.
29. El-Nahas S-M, Mattar R-E, Mohamed A-A. Radioprotective effect of vitamins C and E. Mutat Res 1993;301:143-7.
30. Shimomura Kojima S, Matsumori S. Effect of pre-irradiation with low dose γ-rays on chemically induced hepatotoxicity and glutathione depletion. Anticancer Res 2000;20:1583-6.
31. Pandey B-N, Mishra K-P. Fluorescence and ESR studies on membrane oxidative damage by γ-radiation. Appl Magn Reson 2000;18:483-92.
32. Kasai H. Analysis of a form of oxidative DNA damage, 8-Hydroxy-2- deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis. Mutat Res 1997;387:147-63.
33. Hosseinimehr S-J. Trends in the development of radioprotective agents. Drug Discov Today 2007;12:794-805.
34. Herodin F, Drouet M. Cytokine-based treatment of accidentally irradiated victims and new approaches. Exp Hematol 2005;33:1071-108.
35. Gosselin T-K, Mautner B. Amifostine as a radioprotectant. Clin J Oncol Nurs 2002;6:175-6.
36. Genvresse I, Lange C, Schanz J et al. Tolerability of the cytoprotective agent amifostine in elderly patients receiving chemotherapy: A comparative study. Anticancer Drugs 2004;12:345-9.