-
1
-
-
0000659286
-
Observations respecting an ulcer of peculiar character, which attacks the eyelids and other parts of the face
-
Jacob A. Observations respecting an ulcer of peculiar character, which attacks the eyelids and other parts of the face. Dublin Hosp Rep Commun Med Surg 1827;4:232-239.
-
(1827)
Dublin Hosp Rep Commun Med Surg
, vol.4
, pp. 232-239
-
-
Jacob, A.1
-
2
-
-
0026087955
-
Biology of basal cell carcinoma (part I)
-
Miller SJ. Biology of basal cell carcinoma (part I). J Am Acad Dermatol 1991;24:1-13.
-
(1991)
J Am Acad Dermatol
, vol.24
, pp. 1-13
-
-
Miller, S.J.1
-
3
-
-
0026081793
-
Biology of basal cell carcinoma (part II)
-
Miller SJ. Biology of basal cell carcinoma (part II). J Am Acad Dermatol 1991;24:161-175.
-
(1991)
J Am Acad Dermatol
, vol.24
, pp. 161-175
-
-
Miller, S.J.1
-
4
-
-
0029551028
-
Aetiology and pathogenesis of basal cell carcinoma
-
Miller SJ. Aetiology and pathogenesis of basal cell carcinoma. Clin Dermatol 1995;13:527-536.
-
(1995)
Clin Dermatol
, vol.13
, pp. 527-536
-
-
Miller, S.J.1
-
5
-
-
0036241594
-
Carcinogenesis of basal cell carcinomas: Genetics and molecular mechanisms
-
Lacour JP. Carcinogenesis of basal cell carcinomas: Genetics and molecular mechanisms. Br J Dermatol 2002;146(Suppl 61):17-19.
-
(2002)
Br J Dermatol
, vol.146
, Issue.SUPPL. 61
, pp. 17-19
-
-
Lacour, J.P.1
-
6
-
-
77958463578
-
-
American Cancer Society, January 31, 2012. Available at:, Accessed February 22, 2012
-
American Cancer Society. Skin cancer: Basal and squamous cell. January 31, 2012. Available at: http://documents. cancer.org/acs/groups/cid/documents/ webcontent/003139-pdf.pdf. Accessed February 22, 2012.
-
Skin cancer: Basal and squamous cell
-
-
-
7
-
-
34548398873
-
-
Skin Cancer Foundation, Available at:, Accessed February 27, 2012
-
Skin Cancer Foundation. Skin cancer facts. Available at: www.skincancer.org/ skin-cancer-information/skin-cancerfacts. Accessed February 27, 2012.
-
Skin cancer facts
-
-
-
9
-
-
33947232153
-
Anatomy and organization of human skin
-
In: Burns T, Breathnach S, Cox N, Griffiths C, eds., 7th ed, Oxford, U.K.: Blackwell Science Ltd
-
McGrath JA, Eady RAJ, Pope FM. Anatomy and organization of human skin. In: Burns T, Breathnach S, Cox N, Griffiths C, eds. Rook's Textbook of Dermatology, 7th ed, Oxford, U.K.: Blackwell Science Ltd; 2004:3.1-3.84.
-
(2004)
Rook's Textbook of Dermatology
, pp. 31-384
-
-
McGrath, J.A.1
Eady, R.A.J.2
Pope, F.M.3
-
11
-
-
37549072095
-
-
National Comprehensive Cancer Network, (NCCN Guidelines): Basal cell and squamous cell skin cancers, Version 1.2012. Available at:, Accessed February 27, 2012
-
National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines): Basal cell and squamous cell skin cancers, Version 1.2012. Available at: www.nccn.org/ professionals/physician_gls/pdf/nmsc. pdf. Accessed February 27, 2012.
-
NCCN Clinical Practice Guidelines in Oncology
-
-
-
13
-
-
3042818253
-
Aggressive basal cell carcinoma: Presentation, pathogenesis, and management
-
Walling HW, Fosko SW, Geraminejad PA, et al. Aggressive basal cell carcinoma: Presentation, pathogenesis, and management. Cancer Metastasis Rev 2004;23:389-402.
-
(2004)
Cancer Metastasis Rev
, vol.23
, pp. 389-402
-
-
Walling, H.W.1
Fosko, S.W.2
Geraminejad, P.A.3
-
14
-
-
84872037837
-
-
American Academy of Dermatology, Available at:, Accessed February 27, 2012
-
American Academy of Dermatology. Skin cancer: Who gets and causes. 2012. Available at: www.aad.org/skin-conditions/ dermatology-a-to-z/skin-cancer/whogets-causes. Accessed February 27, 2012.
-
(2012)
Skin cancer: Who gets and causes
-
-
-
15
-
-
7044263345
-
Diagnosis and treatment of basal cell and squamous cell carcinoma
-
Stulberg DL, Crandell B, Fawcett RS. Diagnosis and treatment of basal cell and squamous cell carcinoma. Am Fam Physician 2004;70:1481-1488.
-
(2004)
Am Fam Physician
, vol.70
, pp. 1481-1488
-
-
Stulberg, D.L.1
Crandell, B.2
Fawcett, R.S.3
-
18
-
-
84966634048
-
-
National Cancer Institute, Surveillance Epidemiology and End Results (SEER), Available at:, Accessed February 28, 2012
-
National Cancer Institute, Surveillance Epidemiology and End Results (SEER). SEER stat fact sheets: Other non-epithelial skin. Available at: http://seer.cancer.gov/ statfacts/html/othskin.html. Accessed February 28, 2012
-
SEER stat fact sheets: Other non-epithelial skin
-
-
-
20
-
-
0028284693
-
Nonmelanoma skin cancer in the United States: Incidence
-
Miller DL, Weinstock MA. Nonmelanoma skin cancer in the United States: Incidence. J Am Acad Dermatol 1994;30:774-778.
-
(1994)
J Am Acad Dermatol
, vol.30
, pp. 774-778
-
-
Miller, D.L.1
Weinstock, M.A.2
-
21
-
-
0034522131
-
Changing trends in non-melanoma skin cancer in South Wales, 1988-1998
-
Holmes SA, Malinovszky K, Roberts DL. Changing trends in non-melanoma skin cancer in South Wales, 1988-1998. Br J Dermatol 2000;143:1224-1229.
-
(2000)
Br J Dermatol
, vol.143
, pp. 1224-1229
-
-
Holmes, S.A.1
Malinovszky, K.2
Roberts, D.L.3
-
22
-
-
0027532008
-
Trends in non-melanocytic skin cancer treated in Australia: The second national survey
-
Marks R, Staples M, Giles G. Trends in non-melanocytic skin cancer treated in Australia: The second national survey. Int J Cancer 1993;53:585-590.
-
(1993)
Int J Cancer
, vol.53
, pp. 585-590
-
-
Marks, R.1
Staples, M.2
Giles, G.3
-
23
-
-
4644335843
-
Rapid and continuous increases in incidence rates of basal cell carcinoma in the southeast Netherlands since 1973
-
de Vries E, Louwman M, Bastiaens M, et al. Rapid and continuous increases in incidence rates of basal cell carcinoma in the southeast Netherlands since 1973. J Invest Dermatol 2004;123:634-638.
-
(2004)
J Invest Dermatol
, vol.123
, pp. 634-638
-
-
de Vries, E.1
Louwman, M.2
Bastiaens, M.3
-
24
-
-
0037335413
-
Diagnosing skin malignancy: Assessment of predictive clinical criteria and risk factors
-
Strayer SM, Reynolds PL. Diagnosing skin malignancy: Assessment of predictive clinical criteria and risk factors. J Fam Pract 2003;52:210-218.
-
(2003)
J Fam Pract
, vol.52
, pp. 210-218
-
-
Strayer, S.M.1
Reynolds, P.L.2
-
25
-
-
31644445651
-
Basal cell carcinoma: Biology, morphology, and clinical implications
-
Crowson AN. Basal cell carcinoma: Biology, morphology, and clinical implications. Modern Pathol 2006;19:S127-S149.
-
(2006)
Modern Pathol
, vol.19
-
-
Crowson, A.N.1
-
26
-
-
33747032013
-
The burden of skin diseases: 2004: A joint project of the American Academy of Dermatology Association and the Society for Investigative Dermatology
-
Bickers DR, Lim HW, Margolis D, et al. The burden of skin diseases: 2004: A joint project of the American Academy of Dermatology Association and the Society for Investigative Dermatology. J Am Acad Dermatol 2006;55:490-500.
-
(2006)
J Am Acad Dermatol
, vol.55
, pp. 490-500
-
-
Bickers, D.R.1
Lim, H.W.2
Margolis, D.3
-
27
-
-
85172067606
-
-
National Cancer Institute, July 29, Available at:, Accessed February 27, 2012
-
National Cancer Institute. Basal cell carcinoma of the skin: Treatment. July 29, 2011. Available at: www.cancer.gov/ cancer topics/pdq/treatment/skin/ HealthProfessional. Accessed February 27, 2012.
-
(2011)
Basal cell carcinoma of the skin: Treatment
-
-
-
28
-
-
45749085217
-
Guidelines for the management of basal cell carcinoma
-
Telfer NR, Colver GB, Morton CA. Guidelines for the management of basal cell carcinoma. Br J Dermatol 2008;159:35-48.
-
(2008)
Br J Dermatol
, vol.159
, pp. 35-48
-
-
Telfer, N.R.1
Colver, G.B.2
Morton, C.A.3
-
30
-
-
33749169664
-
Metastatic basal cell carcinoma: A case report and literature review. How accurate is our incidence data?
-
Wadhera A, Fazio M, Bricca G, Stanton O. Metastatic basal cell carcinoma: A case report and literature review. How accurate is our incidence data? Dermatol Online J 2006;12(5):7.
-
(2006)
Dermatol Online J
, vol.12
, Issue.5
, pp. 7
-
-
Wadhera, A.1
Fazio, M.2
Bricca, G.3
Stanton, O.4
-
31
-
-
0025342009
-
Long-term survival following nodal metastases from basal cell carcinoma
-
Raszewski RL, Guyuron B. Long-term survival following nodal metastases from basal cell carcinoma. Ann Plast Surg 1990;24:170-175.
-
(1990)
Ann Plast Surg
, vol.24
, pp. 170-175
-
-
Raszewski, R.L.1
Guyuron, B.2
-
32
-
-
84901289182
-
-
January 30, Available at:, Accessed February 28, 2012
-
FDA approves new treatment for most common type of skin cancer, January 30, 2012. Available at: www.fda.gov/News Events/Newsroom/PressAnnouncements/ ucm289545.htm. Accessed February 28, 2012.
-
(2012)
FDA approves new treatment for most common type of skin cancer
-
-
-
33
-
-
85172056650
-
-
South San Francisco, Calif.: Genentech; January 2012. Available at:, Accessed February 22, 2012
-
Erivedg (vismodegib), prescribing information. South San Francisco, Calif.: Genentech; January 2012. Available at: www. gene.com/gene/products/information/ erivedge/pdf/erivedge_prescribing.pdf. Accessed February 22, 2012.
-
Erivedg (vismodegib), prescribing information
-
-
-
34
-
-
85172067839
-
-
February 16, Available at:, Accessed February 28, 2012
-
Prous Science. Molecule of the month: Vismodegib. February 16, 2012. Available at: www.prous.com/molecules/default. asp?ID=210. Accessed February 28, 2012.
-
(2012)
Prous Science. Molecule of the month: Vismodegib
-
-
-
35
-
-
0035257660
-
Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation
-
Bhardwaj G, Murdoch B, Wu D, et al. Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation. Nat Immunol 2001;2:172-180.
-
(2001)
Nat Immunol
, vol.2
, pp. 172-180
-
-
Bhardwaj, G.1
Murdoch, B.2
Wu, D.3
-
36
-
-
27144487469
-
In vivo analysis of quiescent adult neural stem cells responding to Sonic Hedgehog
-
Ahn S, Joyner AL. In vivo analysis of quiescent adult neural stem cells responding to Sonic Hedgehog. Nature 2005;437:894-897.
-
(2005)
Nature
, vol.437
, pp. 894-897
-
-
Ahn, S.1
Joyner, A.L.2
-
37
-
-
33745728170
-
Hedgehog signaling and Bmi-1 regulate selfrenewal of normal and malignant human mammary stem cells
-
Liu S, Dontu G, Mantle ID, et al. Hedgehog signaling and Bmi-1 regulate selfrenewal of normal and malignant human mammary stem cells. Cancer Res 2006;66:6063-6071.
-
(2006)
Cancer Res
, vol.66
, pp. 6063-6071
-
-
Liu, S.1
Dontu, G.2
Mantle, I.D.3
-
38
-
-
0002452569
-
Developmental roles and clinical significance of Hedgehog signaling
-
McMahon AP, Ingham PW, Tabin CJ. Developmental roles and clinical significance of Hedgehog signaling. Curr Top Dev Biol 2003;53:1-114.
-
(2003)
Curr Top Dev Biol
, vol.53
, pp. 1-114
-
-
McMahon, A.P.1
Ingham, P.W.2
Tabin, C.J.3
-
39
-
-
70349238733
-
Inhibition of the Hedgehog pathway in advanced basal-cell carcinoma
-
Von Hoff DD, LoRusso PM, Rudin CM, et al. Inhibition of the Hedgehog pathway in advanced basal-cell carcinoma. N Engl J Med 2009;361:1164-1172.
-
(2009)
N Engl J Med
, vol.361
, pp. 1164-1172
-
-
von Hoff, D.D.1
LoRusso, P.M.2
Rudin, C.M.3
-
40
-
-
20644431776
-
Sonic hedgehog signaling in basal cell carcinomas
-
Daya-Grosjean L, Couvé-Privat S. Sonic hedgehog signaling in basal cell carcinomas. Cancer Lett 2005;225:181-192.
-
(2005)
Cancer Lett
, vol.225
, pp. 181-192
-
-
Daya-Grosjean, L.1
Couvé-Privat, S.2
-
41
-
-
67650289584
-
Mechanisms of Hedgehog pathway activation in cancer and implications for therapy
-
Scales SJ, de Sauvage FJ. Mechanisms of Hedgehog pathway activation in cancer and implications for therapy. Trends Pharmacol Sci 2009;30:303-312.
-
(2009)
Trends Pharmacol Sci
, vol.30
, pp. 303-312
-
-
Scales, S.J.1
de Sauvage, F.J.2
-
42
-
-
70349244812
-
Treatment of medulloblastoma with Hedgehog pathway inhibitor GDC-0449
-
Rudin CM, Hann CL, Laterra J, et al. Treatment of medulloblastoma with Hedgehog pathway inhibitor GDC-0449. N Engl J Med 2009;361:1173-1178.
-
(2009)
N Engl J Med
, vol.361
, pp. 1173-1178
-
-
Rudin, C.M.1
Hann, C.L.2
Laterra, J.3
-
44
-
-
0031913524
-
Activating Smoothened mutations in sporadic basal-cell carcinoma
-
Xie J, Murone M, Luoh SM, et al. Activating Smoothened mutations in sporadic basal-cell carcinoma. Nature 1998;391:90-92.
-
(1998)
Nature
, vol.391
, pp. 90-92
-
-
Xie, J.1
Murone, M.2
Luoh, S.M.3
-
45
-
-
52649111039
-
Basal cell carcinoma: Attack of the Hedgehog
-
Epstein EH. Basal cell carcinoma: Attack of the Hedgehog. Nat Rev Cancer 2008;8:743-754.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 743-754
-
-
Epstein, E.H.1
-
46
-
-
85172059596
-
Single and multiple-dose IV and oral pharmacokinetics of the Hedgehog pathway inhibitor vismodegib (GDC-0449) during a phase 1 study in healthy female subjects
-
Poster, American Society for Clinical Pharmacology and Therapeutics (ASCPT) Annual Meeting; Dallas, March 2-5, 2011. Available at:, Accessed March 1, 2012
-
Graham RA, Hop CECA, Lum BL, et al. Single and multiple-dose IV and oral pharmacokinetics of the Hedgehog pathway inhibitor vismodegib (GDC-0449) during a phase 1 study in healthy female subjects. Poster, American Society for Clinical Pharmacology and Therapeutics (ASCPT) Annual Meeting; Dallas, March 2-5, 2011. Available at: www.xceleron.com. Accessed March 1, 2012.
-
-
-
Graham, R.A.1
Hop, C.E.C.A.2
Lum, B.L.3
-
47
-
-
79954571612
-
Pharmacokinetics of Hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with locally advanced or metastatic solid tumors: The role of alpha-1-acid glycoprotein binding
-
Graham RA, Lum BL, Cheeti S, et al. Pharmacokinetics of Hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with locally advanced or metastatic solid tumors: The role of alpha-1-acid glycoprotein binding. Clin Cancer Res 2011;17:2512-2520.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 2512-2520
-
-
Graham, R.A.1
Lum, B.L.2
Cheeti, S.3
-
48
-
-
84865245380
-
Pharmacokinetic assessment of drug-drug interaction potential when rosiglitazone or combined oral contraceptive is coadministered with vismodegib in patients with locally advanced or metastatic solid tumors
-
(Abstract No. B188)
-
LoRusso PM, Piha-Paul SA, Colevas AD, et al. Pharmacokinetic assessment of drug-drug interaction potential when rosiglitazone or combined oral contraceptive is coadministered with vismodegib in patients with locally advanced or metastatic solid tumors (Abstract No. B188). Mol Cancer Ther 2011;10(Suppl 1).
-
(2011)
Mol Cancer Ther
, vol.10
, Issue.SUPPL. 1
-
-
LoRusso, P.M.1
Piha-Paul, S.A.2
Colevas, A.D.3
-
49
-
-
79954611501
-
Phase I trial of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with refractory, locally advanced or metastatic solid tumors
-
LoRusso PM, Rudin CM, Reddy JC, et al. Phase I trial of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with refractory, locally advanced or metastatic solid tumors. Clin Cancer Res 2011;17:2502-2511.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 2502-2511
-
-
LoRusso, P.M.1
Rudin, C.M.2
Reddy, J.C.3
-
50
-
-
84861856844
-
Efficacy and safety of vismodegib in advanced basal-cell carcinoma
-
Sekulic A, Migden MR, Oro AE, et al. Efficacy and safety of vismodegib in advanced basal-cell carcinoma. N Engl J Med 2012;366:2171-2179.
-
(2012)
N Engl J Med
, vol.366
, pp. 2171-2179
-
-
Sekulic, A.1
Migden, M.R.2
Oro, A.E.3
-
51
-
-
84872034935
-
FDA approves Erivedge (vismodegib) capsule, the first medicine for adults with advanced basal cell carcinoma
-
Roche, January 30, Available at:, Accessed February 29, 2012
-
FDA approves Erivedge (vismodegib) capsule, the first medicine for adults with advanced basal cell carcinoma. Roche, January 30, 2012. Available at: www. roche.com/media/media_releases/medcor-2012-01-30.htm. Accessed February 29, 2012.
-
(2012)
-
-
-
52
-
-
85172062865
-
Vismodegib Briefing Package: Pediatric ODAC Committee Meeting
-
South San Francisco, Calif.: Genentech; November 1, 2011. Available at:, Accessed February 29, 2012
-
Vismodegib Briefing Package: Pediatric ODAC Committee Meeting. South San Francisco, Calif.: Genentech; November 1, 2011. Available at: www.fda. gov/downloads/AdvisoryCommittees/ CommitteesMeetingMaterials/Drugs/ OncologicDrugsAdvisoryCommittee/ UCM277585.pdf. Accessed February 29, 2012.
-
-
-
-
53
-
-
84872007815
-
FDA accepts Roche's New Drug Application for vismodegib in advanced form of skin cancer
-
Roche Group, November 9, 2011. Available at:, Accessed March 5, 2011
-
FDA accepts Roche's New Drug Application for vismodegib in advanced form of skin cancer. Roche Group, November 9, 2011. Available at: www.roche.com/media/ media_releases/med-cor-2011-11-09. htm. Accessed March 5, 2011.
-
-
-
-
54
-
-
84872006276
-
FDA grants priority review for vismodegib for advanced skin cancer
-
FDA grants priority review for vismodegib for advanced skin cancer. Oncology Times 2011;33(23):5.
-
(2011)
Oncology Times
, vol.33
, Issue.23
, pp. 5
-
-
-
55
-
-
84872029194
-
FDA approves Roche's skin cancer drug Erivedge
-
January 31, Available at:, Accessed February 29, 2012
-
Grogan K. FDA approves Roche's skin cancer drug Erivedge. Pharma Times Online, January 31, 2012. Available at: www.pharmatimes.com/article/12-01-31/ FDA_approves_Roche_s_skin_cancer_ drug_Erivedge.aspx. Accessed February 29, 2012.
-
(2012)
Pharma Times Online
-
-
Grogan, K.1
-
56
-
-
84872039083
-
New type of cancer drug gets approval
-
January 31, (online). Available at:, Accessed February 29, 2012
-
Corbett Dooren J, Winslow R. New type of cancer drug gets approval. The Wall Street Journal January 31, 2012 (online). Available at: http://online.wsj.com. Accessed February 29, 2012.
-
(2012)
The Wall Street Journal
-
-
Corbett Dooren, J.1
Winslow, R.2
|