Screen for agents that induce autolysis in Bacillus subtilis

Antimicrobial Agents and Chemotherapy

Volumn 57, Issue 1, 2013, Pages 229-234

  Lacriola, Christopher J ^a   Falk, Shaun P ^a   Weisblum, Bernard ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 AMINOPENICILLANIC ACID; AMFOMYCIN; AMOXICILLIN; AMPICILLIN; ANTIBIOTIC AGENT; ASPARTOCIN; AUTOLYSIN; BACITRACIN; BAMBERMYCIN; BETA GALACTOSIDASE; CEFALEXIN; CIRCULIN; CITRININ; CLOFAZIMINE; CLOXACILLIN; CYCLOSERINE; DAPTOMYCIN; FOSFOMYCIN; GLYCEROL MONOLAURATE; GRAMICIDIN D; MICONAZOLE; MILTEFOSINE; NIGERICIN; NISIN; RISTOCETIN; TELAVANCIN; TELOMYCIN; TYROTHRICIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VANCOMYCIN;

ANTIBIOTIC RESISTANCE; ARTICLE; AUTOLYSIS; BACILLUS ANTHRACIS; BACILLUS SUBTILIS; BACTERIAL CELL WALL; BACTERIAL STRAIN; CELL MEMBRANE; CONTROLLED STUDY; DRUG EFFICACY; DRUG SCREENING; ENTEROCOCCUS FAECIUM; ESCHERICHIA COLI; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

ANTI-BACTERIAL AGENTS; BACILLUS ANTHRACIS; BACILLUS SUBTILIS; BACTERIAL PROTEINS; BACTERIOLYSIS; BETA-GALACTOSIDASE; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CELL WALL; DRUG DISCOVERY; ENTEROCOCCUS FAECIUM; HIGH-THROUGHPUT SCREENING ASSAYS; MICROBIAL SENSITIVITY TESTS; N-ACETYLMURAMOYL-L-ALANINE AMIDASE; SMALL MOLECULE LIBRARIES; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84872039796     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00741-12     Document Type: Article

References (37)

1. Koch AL. 2003. Bacterial wall as target for attack: past, present, and future research. Clin. Microbiol. Rev. 16:673-687. (Pubitemid 37296555)
2. Green DW. 2002. The bacterial cell wall as a source of antibacterial targets. Expert Opin. Ther. Targets 6:1-19. (Pubitemid 46804569)
3. Schneider T, Sahl HG. 2010. An oldie but a goodie - cell wall biosynthesis as antibiotic target pathway. Int. J. Med. Microbiol. 300:161-169.
4. Silver LL. 2006. Does the cell wall of bacteria remain a viable source of targets for novel antibiotics? Biochem. Pharmacol. 71:996-1005.
5. Silver LL. 2007. Multi-targeting by monotherapeutic antibacterials. Nat. Rev. Drug Discov. 6:41-55. (Pubitemid 46020285)
6. Silver LL. 2011. Challenges of antibacterial discovery. Clin. Microbiol. Rev. 24:71-109.
7. Silver LL. 2012. Rational approaches to antibacterial discovery: pregenomic directed and phenotypic screening, p 33-75. In Dougherty TJ, Pucci MJ (ed), Antibiotic discovery and development. Springer, New York, NY.
8. Kitano K, Tomasz A. 1979. Triggering of autolytic cell wall degradation in Escherichia coli by beta-lactam antibiotics. Antimicrob. Agents Chemother. 16:838-848. (Pubitemid 10082045)
9. Tomasz A, Waks S. 1975. Mechanism of action of penicillin: triggering of the pneumococcal autolytic enzyme by inhibitors of cell wall synthesis. Proc. Natl. Acad. Sci. U. S. A. 72:4162-4166.
10. Choi S, Isaacs A, Clements D, Liu D, Kim H, Scott RW, Winkler JD, DeGrado WF. 2009. De novo design and in vivo activity of conformationally restrained antimicrobial arylamide foldamers. Proc. Natl. Acad. Sci. U. S. A. 106:6968-6973.
11. Fjell CD, Hiss JA, Hancock RE, Schneider G. 2011. Designing antimicrobial peptides: form follows function. Nat. Rev. Drug Discov. 11:37-51.
12. Oren Z, Shai Y. 1998. Mode of action of linear amphipathic alpha-helical antimicrobial peptides. Biopolymers 47:451-463.
13. Rogers HJ, Forsberg CW. 1971. Role of autolysins in the killing of bacteria by some bactericidal antibiotics. J. Bacteriol. 108:1235-1243.
14. Hoover SE, Xu W, Xiao W, Burkholder WF. 2010. Changes in DnaA-dependent gene expression contribute to the transcriptional and developmental response of Bacillus subtilis to manganese limitation in Luria- Bertani medium. J. Bacteriol. 192:3915-3924.
15. Ulijasz AT, Grenader A, Weisblum B. 1996. A vancomycin-inducible lacZ reporter system in Bacillus subtilis: induction by antibiotics that inhibit cell wall synthesis and by lysozyme. J. Bacteriol. 178:6305-6309. (Pubitemid 26365714)
16. Margot P, Pagni M, Karamata D. 1999. Bacillus subtilis 168 gene lytF encodes a gamma-D-glutamate-meso-diaminopimelate muropeptidase expressed by the alternative vegetative sigma factor, sigmaD. Microbiology 145(Part 1):57-65. (Pubitemid 29043577)
17. Gold HS, Unal S, Cercenado E, Thauvin-Eliopoulos C, Eliopoulos GM, Wennersten CB, Moellering RC, Jr. 1993. A gene conferring resistance to vancomycin but not teicoplanin in isolates of Enterococcus faecalis and Enterococcus faecium demonstrates homology with vanB, vanA, and vanC genes of enterococci. Antimicrob. Agents Chemother. 37:1604-1609. (Pubitemid 23226369)
18. Weisblum B, Demohn V. 1969. Erythromycin-inducible resistance in Staphylococcus aureus: survey of antibiotic classes involved. J. Bacteriol. 98:447-452.
19. Ivins BE, Ezzell JW, Jr, Jemski J, Hedlund KW, Ristroph JD, Leppla SH. 1986. Immunization studies with attenuated strains of Bacillus anthracis. Infect. Immun. 52:454-458. (Pubitemid 16117800)
20. Falk SP, Noah JW, Weisblum B. 2010. Screen for inducers of autolysis in Bacillus subtilis. Antimicrob. Agents Chemother. 54:3723-3729.
21. Falk SP, Ulijasz AT, Weisblum B. 2007. Differential assay for high-throughput screening of antibacterial compounds. J. Biomol. Screen. 12: 1102-1108. (Pubitemid 350179698)
22. Tuomanen E, Cozens R, Tosch W, Zak O, Tomasz A. 1986. The rate of killing of Escherichia coli by beta-lactam antibiotics is strictly proportional to the rate of bacterial growth. J. Gen. Microbiol. 132:1297-1304. (Pubitemid 16115638)
23. Mascio CT, Alder JD, Silverman JA. 2007. Bactericidal action of daptomycin against stationary-phase and nondividing Staphylococcus aureus cells. Antimicrob. Agents Chemother. 51:4255-4260. (Pubitemid 350209874)
24. Feng BY, Shoichet BK. 2006. A detergent-based assay for the detection of promiscuous inhibitors. Nat. Protoc. 1:550-553.
25. Kelleher TJ, Lai J-J, DeCourcey JP, Lynch PD, Zenoni M, Tagliani AR. March 2012. High purity lipopeptides. US patent 8129342.
26. Inglese J, Auld DS, Jadhav A, Johnson RL, Simeonov A, Yasgar A, Zheng W, Austin CP. 2006. Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries. Proc. Natl. Acad. Sci. U. S. A. 103:11473-11478. (Pubitemid 44182476)
27. Shai Y. 2002. From innate immunity to de-novo designed antimicrobial peptides. Curr. Pharm. Des. 8:715-725. (Pubitemid 34498561)
28. Tsuchido T, Ahn YH, Takano M. 1987. Lysis of Bacillus subtilis cells by glycerol and sucrose esters of fatty acids. Appl. Environ. Microbiol. 53: 505-508. (Pubitemid 17017538)
29. Tsuchido T, Hiraoka T, Takano M, Shibasaki I. 1985. Involvement of autolysin in cellular lysis of Bacillus subtilis induced by short- and medium-chain fatty acids. J. Bacteriol. 162:42-46. (Pubitemid 15095828)
30. Tsuchido T, Svarachorn A, Soga H, Takano M. 1990. Lysis and aberrant morphology of Bacillus subtilis cells caused by surfactants and their relation to autolysin activity. Antimicrob. Agents Chemother. 34:781-785. (Pubitemid 20142398)
31. Blackman SA, Smith TJ, Foster SJ. 1998. The role of autolysins during vegetative growth of Bacillus subtilis 168. Microbiology 144(Part 1):73-82. (Pubitemid 28045214)
32. Smith TJ, Blackman SA, Foster SJ. 2000. Autolysins of Bacillus subtilis: multiple enzymes with multiple functions. Microbiology 146(Part 2): 249-262. (Pubitemid 30099199)
33. Smith TJ, Foster SJ. 1995. Characterization of the involvement of two compensatory autolysins in mother cell lysis during sporulation of Bacillus subtilis 168. J. Bacteriol. 177:3855-3862.
34. Neumann A, Baginski M, Czub J. 2010. How do sterols determine the antifungal activity of amphotericin B? Free energy of binding between the drug and its membrane targets. J. Am. Chem. Soc. 132:18266-18272.
35. Silverman JA, Perlmutter NG, Shapiro HM. 2003. Correlation of daptomycin bactericidal activity and membrane depolarization in Staphylococcus aureus. Antimicrob. Agents Chemother. 47:2538-2544. (Pubitemid 36919456)
36. Lamsa A, Liu WT, Dorrestein PC, Pogliano K. 2012. The Bacillus subtilis cannibalism toxin SDP collapses the proton motive force and induces autolysis. Mol. Microbiol. 84:486-500.
37. Gründling A, Manson MD, Young R. 2001. Holins kill without warning. Proc. Natl. Acad. Sci. U. S. A. 98:9348-9352. (Pubitemid 32743919)