Joint X-ray crystallographic and molecular dynamics study of cellobiohydrolase i from Trichoderma harzianum: Deciphering the structural features of cellobiohydrolase catalytic activity

FEBS Journal

Volumn 280, Issue 1, 2013, Pages 56-69

  Textor, Larissa C ^a   Colussi, Francieli ^a   Silveira, Rodrigo L ^b   Serpa, Viviane ^a   De Mello, Bruno L ^a   Muniz, João Renato C ^a   Squina, Fabio M ^c   Pereira Jr , Nei ^d   Skaf, Munir S ^b   Polikarpov, Igor ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

^c BRAZILIAN CENTER FOR RESEARCH IN ENERGY AND MATERIALS CNPEM   (Brazil)

^d FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

biomass; cellobiohydrolase; enzymatic hydrolysis; molecular dynamics; X ray structure

Indexed keywords

ALANINE; CELLOBIOHYDROLASE 1; FUNGAL ENZYME; GLUCOSIDE; TYROSINE; UNCLASSIFIED DRUG; VALINE;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME DEGRADATION; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; HYPOCREA JECORINA; HYPOCREA LIXII; INHIBITION KINETICS; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RESIDUE ANALYSIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; CELLULOSE 1,4-BETA-CELLOBIOSIDASE; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; KINETICS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, SECONDARY; STRUCTURAL HOMOLOGY, PROTEIN; TRICHODERMA;

FUNGI; HYPOCREA JECORINA; HYPOCREA LIXII;

EID: 84872039730     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12049     Document Type: Article

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