Two hits are better than one: Membrane-active and DNA binding-related double-action mechanism of NK-18, a novel antimicrobial peptide derived from mammalian NK-lysin

Antimicrobial Agents and Chemotherapy

Volumn 57, Issue 1, 2013, Pages 220-228

  Yan, Jiexi ^a   Wang, Kairong ^a   Dang, Wen ^a   Chen, Ru ^a   Xie, Junqiu ^a   Zhang, Bangzhi ^a   Song, Jingjing ^a   Wang, Rui ^a  

^a LANZHOU UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CALCEIN; DNA; NK 18; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

ABSORPTION SPECTROSCOPY; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL MEMBRANE; BACTERIAL OUTER MEMBRANE; CONFOCAL LASER MICROSCOPY; CYTOPLASM; CYTOTOXIC T LYMPHOCYTE; DRUG DNA BINDING; ESCHERICHIA COLI; FLOW CYTOMETRY; MINIMUM INHIBITORY CONCENTRATION; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; TRANSMISSION ELECTRON MICROSCOPY;

ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CYTOPLASM; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ESCHERICHIA COLI; KINETICS; MICROBIAL SENSITIVITY TESTS; MICROSCOPY, ELECTRON, TRANSMISSION; PROTEOLIPIDS; SOLID-PHASE SYNTHESIS TECHNIQUES; STAPHYLOCOCCUS AUREUS; UNILAMELLAR LIPOSOMES;

EID: 84872017691     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01619-12     Document Type: Article

References (44)

1. Alanis AJ. 2005. Resistance to antibiotics: are we in the post-antibiotic era? Arch. Med. Res. 36:697-705. (Pubitemid 41436239)
2. Heymann DL. 2006 Resistance to anti-infective drugs and the threat to public health. Cell 124:671-675. (Pubitemid 43261440)
3. Straand J, Gradmann C, Lindbæk M, Simonsen GS. 2008. Antibiotic development and resistance, p 200-211. In Kris H (ed), International encyclopedia of public health. Academic Press, Oxford, United Kingdom.
4. Chen Y, Guarnieri MT, Vasil AI, Vasil ML, Mant CT, Hodges RS. 2007. Role of peptide hydrophobicity in the mechanism of action of {alpha}-helical antimicrobial peptides. Antimicrob. Agents Chemother. 51:1398-1406. (Pubitemid 46586822)
5. Kraus D, Peschel A. 2006. Molecular mechanisms of bacterial resistance to antimicrobial peptides, antimicrobial peptides and human disease, p 231-250. In Shafer WM (ed), vol 306. Springer, Berlin, Germany.
6. Zasloff M. 2002. Antimicrobial peptides of multicellular organisms. Nature 415:389-395. (Pubitemid 34100944)
7. Jenssen H, Hamill P, Hancock REW. 2006. Peptide antimicrobial agents. Clin. Microbiol. Rev. 19:491-511. (Pubitemid 44137212)
8. Nicolas P, Mor A. 1995. Peptides as weapons against microorganisms in the chemical defense system of vertebrates. Annu. Rev. Microbiol. 49:277-304.
9. Boman HG. 1995. Peptide antibiotics and their role in innate immunity. Annu. Rev. Immunol. 13:61-92.
10. Hancock REW, Diamond G. 2000. The role of cationic antimicrobial peptides in innate host defences. Trends Microbiol. 8:402-410.
11. Oppenheim JJ, Biragyn A, Kwak LW, Yang D. 2003. Roles of antimicrobial peptides such as defensins in innate and adaptive immunity. Ann. Rheum. Dis. 62(Suppl. 2):ii17-ii21.
12. Wang K, Yan J, Liu X, Zhang J, Chen R, Zhang B, Dang W, Zhang W, Kai M, Song J, Wang R. 2011. Novel cytotoxicity exhibition mode of polybia-CP, a novel antimicrobial peptide from the venom of the social wasp Polybia paulista. Toxicology 288:27-33.
13. Wang Z, Wang G. 2004. APD: the antimicrobial peptide database. Nucleic Acids Res. 32:D590-D592. doi:10.1093/nar/gkh025. (Pubitemid 38081727)
14. Yan J-X, Wang K-R, Chen R, Song J-J, Zhang B-Z, Dang W, Zhang W, Wang R. 2012. Membrane active antitumor activity of NK-18, a mammalian NK-lysin-derived cationic antimicrobial peptide. Biochimie 94:184-191.
15. Fields GB, Noble RL. 1990. Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids. Int. J. Pept. Protein Res. 35:161-214. (Pubitemid 20126875)
16. Wender PA, Mitchell DJ, Pattabiraman K, Pelkey ET, Steinman L, Rothbard JB. 2000. The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters. Proc. Natl. Acad. Sci. U. S. A. 97:13003-13008.
17. Takemura H, Kaku M, Kohno S, Hirakata Y, Tanaka H, Yoshida R, Tomono K, Koga H, Wada A, Hirayama T, Kamihira S. 1996. Evaluation of susceptibility of gram-positive and -negative bacteria to human defensins by using radial diffusion assay. Antimicrob. Agents Chemother. 40:2280-2284. (Pubitemid 26328031)
18. Joshi S, Bisht GS, Rawat DS, Kumar A, Kumar R, Maiti S, Pasha S. 2010. Interaction studies of novel cell selective antimicrobial peptides with model membranes and E. coli ATCC 11775. Biochim. Biophys. Acta 1798:1864-1875.
19. CLSI. 2006. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard M7-A7. CLSI, Wayne, PA.
20. Pag U, Oedenkoven M, Papo N, Oren Z, Shai Y, Sahl H-G. 2004. In vitro activity and mode of action of diastereomeric antimicrobial peptides against bacterial clinical isolates. J. Antimicrob. Chemother. 53:230-239. (Pubitemid 38239955)
21. Jang WS, Kim HK, Lee KY, Kim SA, Han YS, Lee IH. 2006. Antifungal activity of synthetic peptide derived from halocidin, antimicrobial peptide from the tunicate, Halocynthia aurantium. FEBS Lett. 580:1490-1496. (Pubitemid 43222020)
22. Wang B, Navath RS, Menjoge AR, Balakrishnan B, Bellair R, Dai H, Romero R, Kannan S, Kannan RM. 2010. Inhibition of bacterial growth and intramniotic infection in a guinea pig model of chorioamnionitis using PAMAM dendrimers. Int. J. Pharm. 395:298-308.
23. Je J-Y, Kim S-K. 2006. Chitosan derivatives killed bacteria by disrupting the outer and inner membrane. J. Agric. Food Chem. 54:6629-6633. (Pubitemid 44426938)
24. Papo N, Oren Z, Pag U, Sahl H-G, Shai Y. 2002. The consequence of sequence alteration of an amphipathic α-helical antimicrobial peptide and its diastereomers. J. Biol. Chem. 277:33913-33921.
25. Zhu WL, Song YM, Park Y, Park KH, Yang S-T, Kim JI, Park I-S, Hahm K-S, Shin SY. 2007. Substitution of the leucine zipper sequence in melittin with peptoid residues affects self-association, cell selectivity, and mode of action. Biochim. Biophys. Acta 1768:1506-1517. (Pubitemid 46782713)
26. Beckloff N, Laube D, Castro T, Furgang D, Park S, Perlin D, Clements D, Tang H, Scott RW, Tew GN, Diamond G. 2007. Activity of an antimicrobial peptide mimetic against planktonic and biofilm cultures of oral pathogens. Antimicrob. Agents Chemother. 51:4125-4132. (Pubitemid 350057814)
27. van Soolingen D, Hermans PW, de Haas PE, Soll DR, van Embden JD. 1991. Occurrence and stability of insertion sequences in Mycobacterium tuberculosis complex strains: evaluation of an insertion sequence-dependent DNA polymorphism as a tool in the epidemiology of tuberculosis. J. Clin. Microbiol. 29:2578-2586.
28. Amagliani G, Giammarini C, Omiccioli E, Brandi G, Magnani M. 2007. Detection of Listeria monocytogenes using a commercial PCR kit and different DNA extraction methods. Food Control 18:1137-1142.
29. Tang Y-L, Shi Y-H, Zhao W, Hao G, Le G-W. 2009. Interaction of MDpep9, a novel antimicrobial peptide from Chinese traditional edible larvae of housefly, with Escherichia coli genomic DNA. Food Chem. 115:867-872.
30. Lande R, Gregorio J, Facchinetti V, Chatterjee B, Wang Y-H, Homey B, Cao W, Wang Y-H, Su B, Nestle FO, Zal T, Mellman I, Schroder J-M, Liu Y-J, Gilliet M. 2007. Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide. Nature 449:564-569. (Pubitemid 47525141)
31. Loh B, Grant C, Hancock RE. 1984. Use of the fluorescent probe 1-N-phenylnaphthylamine to study the interactions of aminoglycoside antibiotics with the outer membrane of Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 26:546-551. (Pubitemid 14018094)
32. Falla T, Hancock R. 1997. Improved activity of a synthetic indolicidin analog. Antimicrob. Agents Chemother. 41:771-775. (Pubitemid 27150529)
33. Glukhov E, Stark M, Burrows LL, Deber CM. 2005. Basis for selectivity of cationic antimicrobial peptides for bacterial versus mammalian membranes. J. Biol. Chem. 280:33960-33967. (Pubitemid 41443116)
34. Henzler Wildman KA, Lee DK, Ramamoorthy A. 2003. Mechanism of lipid bilayer disruption by the human antimicrobial peptide, LL-37. Biochemistry 42:6545-6558. (Pubitemid 36665830)
35. Oren Z, Shai Y. 1998. Mode of action of linear amphipathic α-helical antimicrobial peptides. Pept. Sci. 47:451-463.
36. Wang K, Yan J, Chen R, Dang W, Zhang B, Zhang W, Song J, Wang R. 2012. Membrane-active action mode of polybia-CP, a novel antimicrobial peptide isolated from the venom of Polybia paulista. Antimicrob. Agents Chemother. 56:3318-3323.
37. Wu M, Maier E, Benz R, Hancock RE. 1999. Mechanism of interaction of different classes of cationic antimicrobial peptides with planar bilayers and with the cytoplasmic membrane of Escherichia coli. Biochemistry 38:7235-7242.
38. Brogden KA. 2005. Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? Nat. Rev. Microbiol. 3:238-250. (Pubitemid 40298223)
39. Kawasaki H, Koyama T, Conlon JM, Yamakura F, Iwamuro S. 2008. Antimicrobial action of histone H2B in Escherichia coli: evidence for membrane translocation and DNA-binding of a histone H2B fragment after proteolytic cleavage by outer membrane proteinase T. Biochimie 90:1693-1702.
40. Park CB, Kim HS, Kim SC. 1998. Mechanism of action of the antimicrobial peptide buforin II: buforin II kills microorganisms by penetrating the cell membrane and inhibiting cellular functions. Biochem. Biophys. Res. Commun. 244:253-257. (Pubitemid 28419934)
41. Hancock REW. 1984. Alterations in outer membrane permeability. Annu. Rev. Microbiol. 38:237-264.
42. Matsuzaki K. 1999. Why and how are peptide-lipid interactions utilized for self-defense? Magainins and tachyplesins as archetypes. Biochim. Biophys. Acta 1462:1-10.
43. Cho JH, Kim SC. 2010. Non-membrane targets of antimicrobial peptides: novel therapeutic opportunities? In Wang G (ed), Antimicrobial peptides: discovery, design and novel therapeutic strategies. CABI Publishing, Wallingford, United Kingdom.
44. Jang SA, Kim H, Lee JY, Shin JR, Kim DJ, Cho JH, Kim SC. 2012. Mechanism of action and specificity of antimicrobial peptides designed based on buforin IIb. Peptides 34:283-289.