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Volumn 8, Issue 12, 2012, Pages

SLI-1 Cbl Inhibits the Engulfment of Apoptotic Cells in C. elegans through a Ligase-Independent Function

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; CBL PROTEIN; GUANOSINE TRIPHOSPHATASE; PROTEIN SLI 1; RAC PROTEIN; RING FINGER PROTEIN; TYROSINE KINASE RECEPTOR; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

EID: 84872013502     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003115     Document Type: Article
Times cited : (10)

References (61)
  • 1
    • 15944373937 scopus 로고    scopus 로고
    • Clearance of apoptotic cells in Caenorhabditis elegans
    • Mangahas P, Zhou Z, (2005) Clearance of apoptotic cells in Caenorhabditis elegans. Semin Cell Dev Biol 16: 295-306.
    • (2005) Semin Cell Dev Biol , vol.16 , pp. 295-306
    • Mangahas, P.1    Zhou, Z.2
  • 2
    • 33646867879 scopus 로고    scopus 로고
    • C. elegans Dynamin mediates the signaling of phagocytic receptor CED-1 for the engulfment and degradation of apoptotic cells
    • Yu X, Odera S, Chuang C, Lu N, Zhou Z, (2006) C. elegans Dynamin mediates the signaling of phagocytic receptor CED-1 for the engulfment and degradation of apoptotic cells. Developmental Cell 10: 743-757.
    • (2006) Developmental Cell , vol.10 , pp. 743-757
    • Yu, X.1    Odera, S.2    Chuang, C.3    Lu, N.4    Zhou, Z.5
  • 3
    • 33744508200 scopus 로고    scopus 로고
    • Dynamin as a mover and pincher during cell migration and invasion
    • Kruchten AE, (2006) Dynamin as a mover and pincher during cell migration and invasion. Journal of Cell Science 119: 1683-1690.
    • (2006) Journal of Cell Science , vol.119 , pp. 1683-1690
    • Kruchten, A.E.1
  • 4
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • Etienne-Manneville S, Hall A, (2002) Rho GTPases in cell biology. Nature 420: 629-635.
    • (2002) Nature , vol.420 , pp. 629-635
    • Etienne-Manneville, S.1    Hall, A.2
  • 5
    • 0036045768 scopus 로고    scopus 로고
    • Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex
    • Brugnera E, Haney L, Grimsley C, Lu M, Walk SF, et al. (2002) Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex. Nat Cell Biol 4: 574-582.
    • (2002) Nat Cell Biol , vol.4 , pp. 574-582
    • Brugnera, E.1    Haney, L.2    Grimsley, C.3    Lu, M.4    Walk, S.F.5
  • 6
    • 14544290056 scopus 로고    scopus 로고
    • Two pathways converge at CED-10 to mediate actin rearrangement and corpse removal in C. elegans
    • Kinchen JM, Cabello J, Klingele D, Wong K, Feichtinger R, et al. (2005) Two pathways converge at CED-10 to mediate actin rearrangement and corpse removal in C. elegans. Nature 434: 93-99.
    • (2005) Nature , vol.434 , pp. 93-99
    • Kinchen, J.M.1    Cabello, J.2    Klingele, D.3    Wong, K.4    Feichtinger, R.5
  • 7
    • 0035195553 scopus 로고    scopus 로고
    • Three C. elegans Rac proteins and several alternative Rac regulators control axon guidance, cell migration and apoptotic cell phagocytosis
    • Lundquist EA, Reddien PW, Hartwieg E, Horvitz HR, Bargmann CI, (2001) Three C. elegans Rac proteins and several alternative Rac regulators control axon guidance, cell migration and apoptotic cell phagocytosis. Development 128: 4475-4488.
    • (2001) Development , vol.128 , pp. 4475-4488
    • Lundquist, E.A.1    Reddien, P.W.2    Hartwieg, E.3    Horvitz, H.R.4    Bargmann, C.I.5
  • 8
    • 19944376460 scopus 로고    scopus 로고
    • Phagocytosis of apoptotic cells is regulated by a UNC-73/TRIO-MIG-2/RhoG signaling module and armadillo repeats of CED-12/ELMO
    • deBakker CD, Haney LB, Kinchen JM, Grimsley C, Lu M, et al. (2004) Phagocytosis of apoptotic cells is regulated by a UNC-73/TRIO-MIG-2/RhoG signaling module and armadillo repeats of CED-12/ELMO. Curr Biol 14: 2208-2216.
    • (2004) Curr Biol , vol.14 , pp. 2208-2216
    • deBakker, C.D.1    Haney, L.B.2    Kinchen, J.M.3    Grimsley, C.4    Lu, M.5
  • 9
    • 0345374587 scopus 로고    scopus 로고
    • Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12
    • Wang X, Wu Y-C, Fadok VA, Lee M-C, Gengyo-Ando K, et al. (2003) Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12. Science 302: 1563-1566.
    • (2003) Science , vol.302 , pp. 1563-1566
    • Wang, X.1    Wu, Y.-C.2    Fadok, V.A.3    Lee, M.-C.4    Gengyo-Ando, K.5
  • 10
    • 77949487317 scopus 로고    scopus 로고
    • Engulfment of apoptotic cells in C. elegans is mediated by Integrin α/SRC signaling
    • doi:10.1016/j.cub.2010.01.062
    • Hsu T-Y, Wu Y-C, (2010) Engulfment of apoptotic cells in C. elegans is mediated by Integrin α/SRC signaling. Current Biology 20: 477-486 doi:10.1016/j.cub.2010.01.062.
    • (2010) Current Biology , vol.20 , pp. 477-486
    • Hsu, T.-Y.1    Wu, Y.-C.2
  • 11
    • 45149101493 scopus 로고    scopus 로고
    • Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling
    • Ziegenfuss JS, Biswas R, Avery MA, Hong K, Sheehan AE, et al. (2008) Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling. Nature 453: 935-939.
    • (2008) Nature , vol.453 , pp. 935-939
    • Ziegenfuss, J.S.1    Biswas, R.2    Avery, M.A.3    Hong, K.4    Sheehan, A.E.5
  • 12
    • 54549121474 scopus 로고    scopus 로고
    • Undertaker, a Drosophila junctophilin, links Draper-mediated phagocytosis and calcium homeostasis
    • Cuttell L, Vaughan A, Silva E, Escaron C, Lavine M, et al. (2008) Undertaker, a Drosophila junctophilin, links Draper-mediated phagocytosis and calcium homeostasis. cell 135: 524-534.
    • (2008) Cell , vol.135 , pp. 524-534
    • Cuttell, L.1    Vaughan, A.2    Silva, E.3    Escaron, C.4    Lavine, M.5
  • 13
    • 70349168768 scopus 로고    scopus 로고
    • An essential role for calcium flux in phagocytes for apoptotic cell engulfment and the anti-inflammatory response
    • Gronski MA, Kinchen JM, Juncadella IJ, Franc NC, Ravichandran KS, (2009) An essential role for calcium flux in phagocytes for apoptotic cell engulfment and the anti-inflammatory response. Cell Death Differ 16: 1323-1331.
    • (2009) Cell Death Differ , vol.16 , pp. 1323-1331
    • Gronski, M.A.1    Kinchen, J.M.2    Juncadella, I.J.3    Franc, N.C.4    Ravichandran, K.S.5
  • 14
    • 65949107540 scopus 로고    scopus 로고
    • Abl Kinase inhibits the engulfment of apopotic cells in Caenorhabditis elegans
    • doi:10.1371/journal.pbio.1000099
    • Hurwitz ME, Vanderzalm PJ, Bloom L, Goldman J, Garriga G, et al. (2009) Abl Kinase inhibits the engulfment of apopotic cells in Caenorhabditis elegans. PLoS Biol 7: e99 doi:10.1371/journal.pbio.1000099.
    • (2009) PLoS Biol , vol.7
    • Hurwitz, M.E.1    Vanderzalm, P.J.2    Bloom, L.3    Goldman, J.4    Garriga, G.5
  • 15
    • 0032403083 scopus 로고    scopus 로고
    • WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac
    • Miki H, Suetsugu S, Takenawa T, (1998) WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac. EMBO J 17: 6932-6941.
    • (1998) EMBO J , vol.17 , pp. 6932-6941
    • Miki, H.1    Suetsugu, S.2    Takenawa, T.3
  • 16
    • 0037102301 scopus 로고    scopus 로고
    • Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
    • Eden S, Rohatgi R, Podtelejnikov AV, Mann M, Kirschner MW, (2002) Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck. Nature 418: 790-793.
    • (2002) Nature , vol.418 , pp. 790-793
    • Eden, S.1    Rohatgi, R.2    Podtelejnikov, A.V.3    Mann, M.4    Kirschner, M.W.5
  • 17
    • 0036499989 scopus 로고    scopus 로고
    • The GEX-2 and GEX-3 proteins are required for tissue morphogenesis and cell migrations in C. elegans
    • Soto MC, Qadota H, Kasuya K, Inoue M, Tsuboi D, et al. (2002) The GEX-2 and GEX-3 proteins are required for tissue morphogenesis and cell migrations in C. elegans. Genes Dev 16: 620-632.
    • (2002) Genes Dev , vol.16 , pp. 620-632
    • Soto, M.C.1    Qadota, H.2    Kasuya, K.3    Inoue, M.4    Tsuboi, D.5
  • 18
    • 56449091763 scopus 로고    scopus 로고
    • The WAVE/SCAR complex promotes polarized cell movements and actin enrichment in epithelia during C. elegans embryogenesis
    • Patel F, Bernadskaya Y, Chen E, Jobanputra A, Pooladi Z, et al. (2008) The WAVE/SCAR complex promotes polarized cell movements and actin enrichment in epithelia during C. elegans embryogenesis. Developmental Biology pp. 37.
    • (2008) Developmental Biology , pp. 37
    • Patel, F.1    Bernadskaya, Y.2    Chen, E.3    Jobanputra, A.4    Pooladi, Z.5
  • 19
    • 0347379920 scopus 로고    scopus 로고
    • Engulfment of apoptotic cells is negatively regulated by Rho-mediated signaling
    • Tosello-Trampont A-C, Nakada-Tsukui K, Ravichandran KS, (2003) Engulfment of apoptotic cells is negatively regulated by Rho-mediated signaling. J Biol Chem 278: 49911-49919.
    • (2003) J Biol Chem , vol.278 , pp. 49911-49919
    • Tosello-Trampont, A.-C.1    Nakada-Tsukui, K.2    Ravichandran, K.S.3
  • 20
    • 78650512821 scopus 로고    scopus 로고
    • Loss of the RhoGAP SRGP-1 promotes the clearance of dead and injured cells in Caenorhabditis elegans
    • Neukomm LJ, Frei AP, Cabello J, Kinchen JM, Zaidel-Bar R, et al. (2010) Loss of the RhoGAP SRGP-1 promotes the clearance of dead and injured cells in Caenorhabditis elegans. Nat Cell Biol 13: 79-86.
    • (2010) Nat Cell Biol , vol.13 , pp. 79-86
    • Neukomm, L.J.1    Frei, A.P.2    Cabello, J.3    Kinchen, J.M.4    Zaidel-Bar, R.5
  • 21
    • 72949117533 scopus 로고    scopus 로고
    • Caenorhabditis elegans myotubularin MTM-1 negatively regulates the engulfment of apoptotic cells
    • doi:10.1371/journal.pgen.1000679
    • Zou W, Lu Q, Zhao D, Li W, Mapes J, et al. (2009) Caenorhabditis elegans myotubularin MTM-1 negatively regulates the engulfment of apoptotic cells. PLoS Genet 5: e1000679 doi:10.1371/journal.pgen.1000679.
    • (2009) PLoS Genet , vol.5
    • Zou, W.1    Lu, Q.2    Zhao, D.3    Li, W.4    Mapes, J.5
  • 22
    • 79955552492 scopus 로고    scopus 로고
    • The phosphoinositide phosphatase MTM-1 regulates apoptotic cell corpse clearance through CED-5-CED-12 in C. elegans
    • Neukomm LJ, Nicot A-S, Kinchen JM, Almendinger J, Pinto SM, et al. (2011) The phosphoinositide phosphatase MTM-1 regulates apoptotic cell corpse clearance through CED-5-CED-12 in C. elegans. Development 138: 2003-2014.
    • (2011) Development , vol.138 , pp. 2003-2014
    • Neukomm, L.J.1    Nicot, A.-S.2    Kinchen, J.M.3    Almendinger, J.4    Pinto, S.M.5
  • 23
    • 33845729889 scopus 로고    scopus 로고
    • SWAN-1, a Caenorhabditis elegans WD repeat protein of the AN11 family, is a negative regulator of Rac GTPase function
    • doi:10.1534/genetics.106.063115
    • Yang Y, Lu J, Rovnak J, Quackenbush SL, Lundquist EA, (2006) SWAN-1, a Caenorhabditis elegans WD repeat protein of the AN11 family, is a negative regulator of Rac GTPase function. Genetics 174: 1917-1932 doi:10.1534/genetics.106.063115.
    • (2006) Genetics , vol.174 , pp. 1917-1932
    • Yang, Y.1    Lu, J.2    Rovnak, J.3    Quackenbush, S.L.4    Lundquist, E.A.5
  • 24
    • 79952712455 scopus 로고    scopus 로고
    • A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells
    • doi:10.1073/pnas.1100650108
    • Kao AW, Eisenhut RJ, Martens LH, Nakamura A, Huang A, et al. (2011) A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells. Proc Natl Acad Sci USA 108: 4441-4446 doi:10.1073/pnas.1100650108.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 4441-4446
    • Kao, A.W.1    Eisenhut, R.J.2    Martens, L.H.3    Nakamura, A.4    Huang, A.5
  • 25
    • 33748196233 scopus 로고    scopus 로고
    • The Cbl family proteins: Ring leaders in regulation of cell signaling
    • Swaminathan G, Tsygankov AY, (2006) The Cbl family proteins: Ring leaders in regulation of cell signaling. J Cell Physiol 209: 21-43.
    • (2006) J Cell Physiol , vol.209 , pp. 21-43
    • Swaminathan, G.1    Tsygankov, A.Y.2
  • 26
    • 0033522219 scopus 로고    scopus 로고
    • Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase
    • Meng W, Sawasdikosol S, Burakoff SJ, Eck MJ, (1999) Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase. Nature 398: 84-90.
    • (1999) Nature , vol.398 , pp. 84-90
    • Meng, W.1    Sawasdikosol, S.2    Burakoff, S.J.3    Eck, M.J.4
  • 27
  • 28
    • 34249284476 scopus 로고    scopus 로고
    • Abi-1 forms an epidermal growth factor-inducible complex with Cbl: Role in receptor endocytosis
    • Tanos B, Pendergast A, (2007) Abi-1 forms an epidermal growth factor-inducible complex with Cbl: Role in receptor endocytosis. Cell Signal 19: 1602-1609.
    • (2007) Cell Signal , vol.19 , pp. 1602-1609
    • Tanos, B.1    Pendergast, A.2
  • 29
    • 0029124883 scopus 로고
    • Similarity of sli-1, a regulator of vulval development in C. elegans, to the mammalian proto-oncogene c-cbl
    • Yoon CH, Lee J, Jongeward GD, Sternberg PW, (1995) Similarity of sli-1, a regulator of vulval development in C. elegans, to the mammalian proto-oncogene c-cbl. Science 269: 1102-1105.
    • (1995) Science , vol.269 , pp. 1102-1105
    • Yoon, C.H.1    Lee, J.2    Jongeward, G.D.3    Sternberg, P.W.4
  • 30
    • 0033748123 scopus 로고    scopus 로고
    • Requirements of multiple domains of SLI-1, a Caenorhabditis elegans homologue of c-Cbl, and an inhibitory tyrosine in LET-23 in regulating vulval differentiation
    • Yoon CH, Chang C, Hopper NA, Lesa GM, Sternberg PW, (2000) Requirements of multiple domains of SLI-1, a Caenorhabditis elegans homologue of c-Cbl, and an inhibitory tyrosine in LET-23 in regulating vulval differentiation. Mol Biol Cell 11: 4019-4031.
    • (2000) Mol Biol Cell , vol.11 , pp. 4019-4031
    • Yoon, C.H.1    Chang, C.2    Hopper, N.A.3    Lesa, G.M.4    Sternberg, P.W.5
  • 31
    • 0033980846 scopus 로고    scopus 로고
    • c-Cbl localizes to actin lamellae and regulates lamellipodia formation and cell morphology
    • Scaife RM, Langdon WY, (2000) c-Cbl localizes to actin lamellae and regulates lamellipodia formation and cell morphology. Journal of Cell Science 113 Pt 2: 215-226.
    • (2000) Journal of Cell Science , vol.113 , Issue.Pt 2 , pp. 215-226
    • Scaife, R.M.1    Langdon, W.Y.2
  • 32
    • 0344824500 scopus 로고    scopus 로고
    • Rapid microtubule-dependent induction of neurite-like extensions in NIH 3T3 fibroblasts by inhibition of ROCK and Cbl
    • Scaife RM, Job D, Langdon WY, (2003) Rapid microtubule-dependent induction of neurite-like extensions in NIH 3T3 fibroblasts by inhibition of ROCK and Cbl. Mol Biol Cell 14: 4605-4617.
    • (2003) Mol Biol Cell , vol.14 , pp. 4605-4617
    • Scaife, R.M.1    Job, D.2    Langdon, W.Y.3
  • 33
    • 0037442804 scopus 로고    scopus 로고
    • Cbl-ArgBP2 complex mediates ubiquitination and degradation of c-Abl
    • Soubeyran P, Barac A, Szymkiewicz I, Dikic I, (2003) Cbl-ArgBP2 complex mediates ubiquitination and degradation of c-Abl. Biochem J 370: 29-34.
    • (2003) Biochem J , vol.370 , pp. 29-34
    • Soubeyran, P.1    Barac, A.2    Szymkiewicz, I.3    Dikic, I.4
  • 34
    • 0026051936 scopus 로고
    • Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans
    • Ellis RE, Jacobson DM, Horvitz HR, (1991) Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans. Genetics 129: 79-94.
    • (1991) Genetics , vol.129 , pp. 79-94
    • Ellis, R.E.1    Jacobson, D.M.2    Horvitz, H.R.3
  • 35
    • 0028920694 scopus 로고
    • sli-1, a negative regulator of let-23-mediated signaling in C. elegans
    • Jongeward GD, Clandinin TR, Sternberg PW, (1995) sli-1, a negative regulator of let-23-mediated signaling in C. elegans. Genetics 139: 1553-1566.
    • (1995) Genetics , vol.139 , pp. 1553-1566
    • Jongeward, G.D.1    Clandinin, T.R.2    Sternberg, P.W.3
  • 36
    • 33745411180 scopus 로고    scopus 로고
    • Identification and classification of genes that act antagonistically to let-60 Ras signaling in Caenorhabditis elegans vulval development
    • Ceol CJ, Stegmeier F, Harrison MM, Horvitz HR, (2006) Identification and classification of genes that act antagonistically to let-60 Ras signaling in Caenorhabditis elegans vulval development. Genetics 173: 709-726.
    • (2006) Genetics , vol.173 , pp. 709-726
    • Ceol, C.J.1    Stegmeier, F.2    Harrison, M.M.3    Horvitz, H.R.4
  • 37
    • 0022497852 scopus 로고
    • Genetic control of programmed cell death in the nematode C. elegans
    • Ellis HM, Horvitz HR, (1986) Genetic control of programmed cell death in the nematode C. elegans. Cell 44: 817-829.
    • (1986) Cell , vol.44 , pp. 817-829
    • Ellis, H.M.1    Horvitz, H.R.2
  • 38
    • 0033680282 scopus 로고    scopus 로고
    • The ced-8 gene controls the timing of programmed cell deaths in C. elegans
    • Stanfield GM, Horvitz HR, (2000) The ced-8 gene controls the timing of programmed cell deaths in C. elegans. Mol Cell 5: 423-433.
    • (2000) Mol Cell , vol.5 , pp. 423-433
    • Stanfield, G.M.1    Horvitz, H.R.2
  • 40
    • 0032728443 scopus 로고    scopus 로고
    • Mutational analysis of the Caenorhabditis elegans cell-death gene ced-3
    • Shaham S, Reddien PW, Davies B, Horvitz HR, (1999) Mutational analysis of the Caenorhabditis elegans cell-death gene ced-3. Genetics 153: 1655-1671.
    • (1999) Genetics , vol.153 , pp. 1655-1671
    • Shaham, S.1    Reddien, P.W.2    Davies, B.3    Horvitz, H.R.4
  • 41
    • 0035849886 scopus 로고    scopus 로고
    • Phagocytosis promotes programmed cell death in C. elegans
    • Reddien PW, Cameron S, Horvitz HR, (2001) Phagocytosis promotes programmed cell death in C. elegans. Nature 412: 198-202.
    • (2001) Nature , vol.412 , pp. 198-202
    • Reddien, P.W.1    Cameron, S.2    Horvitz, H.R.3
  • 42
    • 0035849895 scopus 로고    scopus 로고
    • Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans
    • Hoeppner DJ, Hengartner MO, Schnabel R, (2001) Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans. Nature 412: 202-206.
    • (2001) Nature , vol.412 , pp. 202-206
    • Hoeppner, D.J.1    Hengartner, M.O.2    Schnabel, R.3
  • 43
    • 34250025633 scopus 로고    scopus 로고
    • Engulfment is required for cell competition
    • Li W, Baker N, (2007) Engulfment is required for cell competition. Cell 129: 1215-1225.
    • (2007) Cell , vol.129 , pp. 1215-1225
    • Li, W.1    Baker, N.2
  • 44
    • 0017230019 scopus 로고
    • Development of the reproductive system of Caenorhabditis elegans
    • Hirsh D, Oppenheim D, Klass M, (1976) Development of the reproductive system of Caenorhabditis elegans. Developmental Biology 49: 200-219.
    • (1976) Developmental Biology , vol.49 , pp. 200-219
    • Hirsh, D.1    Oppenheim, D.2    Klass, M.3
  • 45
    • 0019890956 scopus 로고
    • On the control of germ cell development in Caenorhabditis elegans
    • Kimble JE, White JG, (1981) On the control of germ cell development in Caenorhabditis elegans. Developmental Biology 81: 208-219.
    • (1981) Developmental Biology , vol.81 , pp. 208-219
    • Kimble, J.E.1    White, J.G.2
  • 46
    • 0032473981 scopus 로고    scopus 로고
    • C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
    • Wu YC, Horvitz HR, (1998) C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180. Nature 392: 501-504.
    • (1998) Nature , vol.392 , pp. 501-504
    • Wu, Y.C.1    Horvitz, H.R.2
  • 47
    • 21444442110 scopus 로고    scopus 로고
    • Structural characterization of a novel Cbl phosphotyrosine recognition motif in the APS family of adapter proteins
    • Hu J, Hubbard SR, (2005) Structural characterization of a novel Cbl phosphotyrosine recognition motif in the APS family of adapter proteins. J Biol Chem 280: 18943-18949.
    • (2005) J Biol Chem , vol.280 , pp. 18943-18949
    • Hu, J.1    Hubbard, S.R.2
  • 48
    • 0033578408 scopus 로고    scopus 로고
    • SLAP, a dimeric adapter protein, plays a functional role in T cell receptor signaling
    • Tang J, Sawasdikosol S, Chang JH, Burakoff SJ, (1999) SLAP, a dimeric adapter protein, plays a functional role in T cell receptor signaling. Proc Natl Acad Sci USA 96: 9775-9780.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 9775-9780
    • Tang, J.1    Sawasdikosol, S.2    Chang, J.H.3    Burakoff, S.J.4
  • 49
    • 0033555527 scopus 로고    scopus 로고
    • Phosphorylation- and activation-independent association of the tyrosine kinase Syk and the tyrosine kinase substrates Cbl and Vav with tubulin in B-cells
    • Fernandez JA, Keshvara LM, Peters JD, Furlong MT, Harrison ML, et al. (1999) Phosphorylation- and activation-independent association of the tyrosine kinase Syk and the tyrosine kinase substrates Cbl and Vav with tubulin in B-cells. J Biol Chem 274: 1401-1406.
    • (1999) J Biol Chem , vol.274 , pp. 1401-1406
    • Fernandez, J.A.1    Keshvara, L.M.2    Peters, J.D.3    Furlong, M.T.4    Harrison, M.L.5
  • 50
  • 52
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner S, (1974) The genetics of Caenorhabditis elegans. Genetics 77: 71-94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 53
    • 0004291817 scopus 로고
    • and the C. elegans Research Community, Plainview (New York): Cold Spring Harbor Laboratory Press
    • Wood W and the C. elegans Research Community (1988) The nematode Caenorhabditis elegans. Plainview (New York): Cold Spring Harbor Laboratory Press. 667 p.
    • (1988) The nematode Caenorhabditis elegans , pp. 667
    • Wood, W.1
  • 55
    • 0035265833 scopus 로고    scopus 로고
    • dpl-1 DP and efl-1 E2F act with lin-35 Rb to antagonize Ras signaling in C. elegans vulval development
    • Ceol CJ, Horvitz HR, (2001) dpl-1 DP and efl-1 E2F act with lin-35 Rb to antagonize Ras signaling in C. elegans vulval development. Mol Cell 7: 461-473.
    • (2001) Mol Cell , vol.7 , pp. 461-473
    • Ceol, C.J.1    Horvitz, H.R.2
  • 56
    • 0017618537 scopus 로고
    • Post-embryonic cell lineages of the nematode, Caenorhabditis elegans
    • Sulston JE, Horvitz HR, (1977) Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. Developmental Biology 56: 110-156.
    • (1977) Developmental Biology , vol.56 , pp. 110-156
    • Sulston, J.E.1    Horvitz, H.R.2
  • 57
    • 0020557883 scopus 로고
    • Mutations affecting programmed cell deaths in the nematode Caenorhabditis elegans
    • Hedgecock EM, Sulston JE, Thomson JN, (1983) Mutations affecting programmed cell deaths in the nematode Caenorhabditis elegans. Science 220: 1277-1279.
    • (1983) Science , vol.220 , pp. 1277-1279
    • Hedgecock, E.M.1    Sulston, J.E.2    Thomson, J.N.3
  • 58
    • 0032814355 scopus 로고    scopus 로고
    • Mutations affecting symmetrical migration of distal tip cells in Caenorhabditis elegans
    • Nishiwaki K, (1999) Mutations affecting symmetrical migration of distal tip cells in Caenorhabditis elegans. Genetics 152: 985-997.
    • (1999) Genetics , vol.152 , pp. 985-997
    • Nishiwaki, K.1
  • 59
    • 0033771902 scopus 로고    scopus 로고
    • CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans
    • Reddien PW, Horvitz HR, (2000) CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans. Nat Cell Biol 2: 131-136.
    • (2000) Nat Cell Biol , vol.2 , pp. 131-136
    • Reddien, P.W.1    Horvitz, H.R.2
  • 60
    • 0032578911 scopus 로고    scopus 로고
    • Specific interference by ingested dsRNA
    • Timmons L, Fire A, (1998) Specific interference by ingested dsRNA. Nature 395: 854.
    • (1998) Nature , vol.395 , pp. 854
    • Timmons, L.1    Fire, A.2
  • 61
    • 0035229245 scopus 로고    scopus 로고
    • Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans
    • Kamath RS, Martinez-Campos M, Zipperlen P, Fraser AG, Ahringer J, (2001) Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans. Genome Biol 2: 1-10.
    • (2001) Genome Biol , vol.2 , pp. 1-10
    • Kamath, R.S.1    Martinez-Campos, M.2    Zipperlen, P.3    Fraser, A.G.4    Ahringer, J.5


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