EPHX1 gene polymorphisms in alcohol dependence and their distribution among the indian populations

American Journal of Drug and Alcohol Abuse

Volumn 39, Issue 1, 2013, Pages 16-22

  Bhaskar, L V K S ^a,d   Thangaraj, K ^a   Patel, Minarbha ^a   Shah, Anish M ^a   Gopal, K ^a   Saikrishna, L ^b   Tamang, Rakesh ^a   Singh, Lalji ^a,e   Rao, V R ^c  

^a CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

^b SRI VENKATESWARA UNIVERSITY   (India)

^c UNIVERSITY OF DELHI   (India)

^d SRI RAMACHANDRA UNIVERSITY   (India)

^e Genome Foundation   (India)

Author keywords

Allelic variation; EPHX1; India; SNP

Indexed keywords

EPOXIDE HYDROLASE; EPOXIDE HYDROLASE 1; UNCLASSIFIED DRUG;

ADULT; ALCOHOLISM; ARTICLE; CONTROLLED STUDY; DSM-IV; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC LINKAGE; GENOTYPE; HAPLOTYPE; HUMAN; INDIAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ALCOHOLISM; CASE-CONTROL STUDIES; EPOXIDE HYDROLASES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INDIA; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEINS; YOUNG ADULT;

EID: 84872012806     PISSN: 00952990     EISSN: 10979891     Source Type: Journal    
DOI: 10.3109/00952990.2011.643991     Document Type: Article

References (35)

1. Ray LA, Mackillop J,Monti PM. Subjective responses to alcohol consumption as endophenotypes: Advancing behavioral genetics in etiological and treatment models of alcoholism. Subst Use Misuse 2010; 45(11):1742-1765
2. Kendler KS, Davis CG, Kessler RC. The familial aggregation of common psychiatric and substance use disorders in the national comorbidity survey: A family history study. Br J Psychiatry 1997; 170:541-548
3. Rodd ZA, Bertsch BA, Strother WN, Le-Niculescu H, Balaraman Y, Hayden E, Jerome RE, Lumeng L, Nurnberger JI, Jr, Edenberg HJ, McBride WJ, Niculescu AB. Candidate genes, pathways and mechanisms for alcoholism: An expanded convergent functional genomics approach. Pharmacogenomics J 2007; 7(4):222-256
4. Coller JK, Fritz P, Zanger UM, Siegle I, Eichelbaum M, Kroemer HK, Murdter TE. Distribution of microsomal epoxide hydrolase in humans: An immunohistochemical study in normal tissues, and benign and malignant tumours. Histochem J 2001; 33(6):329-336
5. Hartsfield JK, Jr, Sutcliffe MJ, Everett ET, Hassett C, Omiecinski CJ, Saari JA. Assignment1 of microsomal epoxide hydrolase (EPHX1) to human chromosome 1q42.1 by in situ hybridization. Cytogenet Cell Genet 1998; 83(1-2):44-45
6. Hassett C, Aicher L, Sidhu JS, Omiecinski CJ. Human microsomal epoxide hydrolase: Genetic polymorphism and functional expression in vitro of amino acid variants. Hum Mol Genet 1994; 3(3):421-428
7. Tiemersma EW, Omer RE, Bunschoten A, van't Veer P, Kok FJ, Idris MO, Kadaru AM, Fedail SS, Kampman E. Role of genetic polymorphism of glutathione-S-transferase T1 and microsomal epoxide hydrolase in aflatoxin-associated hepatocellular carcinoma. Cancer Epidemiol Biomarkers Prev 2001; 10(7):785-791
8. Ulrich CM, Bigler J,Whitton JA, Bostick R, Fosdick L, Potter JD. Epoxide hydrolase Tyr113His polymorphism is associated with elevated risk of colorectal polyps in the presence of smoking and high meat intake. Cancer Epidemiol Biomarkers Prev 2001; 10(8):875-882
9. Gsur A, Zidek T, Schnattinger K, Feik E, Haidinger G, Hollaus P, Mohn-Staudner A, Armbruster C,Madersbacher S, Schatzl G, Trieb K, Vutuc C, Micksche M. Association of microsomal epoxide hydrolase polymorphisms and lung cancer risk. Br J Cancer 2003; 89(4):702-706
10. Park JY, Schantz SP, Lazarus P. Epoxide hydrolase genotype and orolaryngeal cancer risk: Interaction with GSTM1 genotype. Oral Oncol 2003; 39(5):483-490
11. Abdel-Rahman SZ, Ammenheuser MM, Ward JB, Jr. Human sensitivity to 1,3-butadiene: Role of microsomal epoxide hydrolase polymorphisms. Carcinogenesis 2001; 22(3): 415-423
12. Van de Wiel JA, Fijneman PH, Teeuw KB, Van Ommen B, Noordhoek J, Bos RP. Influence of long-term ethanol treatment on rat liver biotransformation enzymes. Alcohol 1993; 10(5):397-402
13. Rabe-Jablonska J, Bienkiewicz W. [Anxiety disorders in the fourth edition of the classification of mental disorders prepared by the American Psychiatric Association: Diagnostic and statistical manual of mental disorders (DMS-IV - options book]. Psychiatr Pol 1994; 28(2):255-268
14. Thangaraj K, Joshi MB, Reddy AG, Gupta NJ, Chakravarty B, Singh L. CAG repeat expansion in the androgen receptor gene is not associated with male infertility in Indian populations. J Androl 2002; 23(6):815-818
15. Cubells JF, Kobayashi K, Nagatsu T, Kidd KK, Kidd JR, Calafell F, Kranzler HR, Ichinose H, Gelernter J. Population genetics of a functional variant of the dopamine betahydroxylase gene (DBH). Am J Med Genet 1997; 74(4): 374-379
16. Schneider S, Roessli D, Excoffier L. Arlequin v.2.0: A Software for Population Genetics Data Analysis. Geneva, Switzerland: Genetics and Biometry Laboratory, University of Geneva, 2000
17. Barrett JC, Fry B, Maller J, Daly MJ. Haploview: Analysis and visualization of LD and haplotype maps. Bioinformatics 2005; 21(2):263-265
18. Benhamou S, Reinikainen M, Bouchardy C, Dayer P, Hirvonen A. Association between lung cancer and microsomal epoxide hydrolase genotypes. Cancer Res 1998; 58(23): 5291-5293
19. Curtis LR, Hemmer MJ, Courtney LA. Dieldrin induces cytosolic [3H]7, 12-dimethylbenz[a]anthracene binding but not multidrug resistance proteins in rainbow trout liver. J Toxicol Environ Health A 2000; 60(4):275-289
20. Hang J, Zhou W, Wang X, Zhang H, Sun B, Dai H, Su L, Christiani DC.Microsomal epoxide hydrolase, endotoxin, and lung function decline in cotton textile workers. Am J Respir Crit Care Med 2005; 171(2):165-170
21. de Jong DJ, van der Logt EM, van Schaik A, Roelofs HM, Peters WH, Naber TH. Genetic polymorphisms in biotransformation enzymes in Crohn's disease: Association with microsomal epoxide hydrolase. Gut 2003; 52(4): 547-551
22. Gyorffy B, Kocsis I, Vasarhelyi B. Biallelic genotype distributions in papers published in Gut between 1998 and 2003: Altered conclusions after recalculating the Hardy-Weinberg equilibrium. Gut 2004; 53(4):614-615; author reply 615-616
23. Peters WH, van der Logt EM, Te Morsche RH, Roelofs HM, de Jong DJ, Naber TH. No genetic association between EPHX1 and Crohn's disease. Gut 2005; 54(11): 1659-1660
24. Liu Y, Yoshimura K, Hanaoka T, Ohnami S, Kohno T, Yoshida T, Sakamoto H, Sobue T, Tsugane S. Association of habitual smoking and drinking with single nucleotide polymorphism (SNP) in 40 candidate genes: Data from random population-based Japanese samples. J Hum Genet 2005; 50(2):62-68
25. Mitrou PN, Watson MA, Loktionov AS, Cardwell C, Gunter MJ, Atkin WS, Macklin CP, Cecil T, Bishop DT, Primrose J, Bingham SA. Role of NQO1C609T and EPHX1 gene polymorphisms in the association of smoking and alcohol with sporadic distal colorectal adenomas: Results from the UKFSS Study. Carcinogenesis 2007; 28(4): 875-882
26. Sun P, Qian J, Zhang ZB, Wan JX, Wu F, Jin XP, FanWW, Lu DR, Zhao NQ, Christiani DC, Xia ZL. Polymorphisms in phase I and phase II metabolism genes and risk of chronic benzene poisoning in a Chinese occupational population. Carcinogenesis 2008; 29(12):2325-2329
27. Wu X, Gwyn K, Amos CI, Makan N, Hong WK, Spitz MR. The association of microsomal epoxide hydrolase polymorphisms and lung cancer risk in African-Americans and Mexican-Americans. Carcinogenesis 2001; 22(6):923-928
28. Ada AO, Suzen HS, Iscan M. Polymorphisms of microsomal epoxide hydrolase and glutathione S-transferase P1 in a male Turkish population. Int J Toxicol 2007; 26(1):41-46
29. Voho A, Metsola K, Anttila S, Impivaara O, Jarvisalo J, Vainio H, Husgafvel-Pursiainen K, Hirvonen A. EPHX1 gene polymorphisms and individual susceptibility to lung cancer. Cancer Lett 2006; 237(1):102-108
30. Robien K, Curtin K, Ulrich CM, Bigler J, Samowitz W, Caan B, Potter JD, Slattery ML. Microsomal epoxide hydrolase polymorphisms are not associated with colon cancer risk. Cancer Epidemiol Biomarkers Prev 2005; 14(5): 1350-1352
31. Ma M, Umemura T, Mori Y, Gong Y, Saijo Y, Sata F, Kawai T, Kishi R. Influence of genetic polymorphisms of styrenemetabolizing enzymes and smoking habits on levels of urinary metabolites after occupational exposure to styrene. Toxicol Lett 2005; 160(1):84-91
32. Cortessis V, Siegmund K, Chen Q, Zhou N, Diep A, Frankl H, Lee E, Zhu QS, Haile R, Levy D. A case-control study of microsomal epoxide hydrolase, smoking, meat consumption, glutathione S-transferaseM3, and risk of colorectal adenomas. Cancer Res 2001; 61(6):2381-2385
33. Lee J, Nordestgaard BG, Dahl M. EPHX1 polymorphisms, COPD and asthma in 47,000 individuals and in meta-analysis. Eur Respir J 2010; 37(1):18-25
34. Chappell S, Daly L, Morgan K, Guetta-Baranes T, Roca J, Rabinovich R, Lotya J, Millar AB, Donnelly SC, Keatings V, MacNee W, Stolk J, Hiemstra PS, Miniati M, Monti S, O'Connor CM, Kalsheker N. Genetic variants of microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD. Eur Respir J 2008; 32(4):931-937
35. Yang X, Liang SH, Weyant DM, Lazarus P, Gallagher CJ, Omiecinski CJ. The expression of human microsomal epoxide hydrolase is predominantly driven by a genetically polymorphic far upstream promoter. J Pharmacol Exp Ther 2009; 330(1):23-30