-
1
-
-
34447274229
-
Genetic determinants of emphysema distribution in the national emphysema treatment trial
-
DeMeo DL, Hersh CP, Hoffman EA, et al. Genetic determinants of emphysema distribution in the national emphysema treatment trial. Am J Respir Crit Care Med 2007; 176: 42-48.
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 42-48
-
-
DeMeo, D.L.1
Hersh, C.P.2
Hoffman, E.A.3
-
2
-
-
33750094349
-
Genetic association between COPD and polymorphisms in TNF, ADRB2 and EPHX1
-
Brøgger J, Steen VM, Eiken HG, et al. Genetic association between COPD and polymorphisms in TNF, ADRB2 and EPHX1. Eur Respir J 2006; 27: 682-688.
-
(2006)
Eur Respir J
, vol.27
, pp. 682-688
-
-
Brøgger, J.1
Steen, V.M.2
Eiken, H.G.3
-
3
-
-
33751236493
-
Developing COPD: A 25 year follow up study of the general population
-
DOI 10.1136/thx.2006.062802
-
Lokke A, Lange P, Scharling H, et al. Developing COPD: a 25-year follow up study of the general population. Thorax 2006; 61: 935-939. (Pubitemid 44787161)
-
(2006)
Thorax
, vol.61
, Issue.11
, pp. 935-939
-
-
Lokke, A.1
Lange, P.2
Scharling, H.3
Fabricius, P.4
Vestbo, J.5
-
4
-
-
0031807729
-
Genetic epidemiology of severe, early-onset chronic obstructive pulmonary disease. Risk to relatives for airflow obstruction and chronic bronchitis
-
Silverman EK, Chapman HA, Drazen JM, et al. Genetic epidemiology of severe, early-onset chronic obstructive pulmonary disease. Risk to relatives for airflow obstruction and chronic bronchitis. Am J Respir Crit Care Med 1998; 157: 1770-1778.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 1770-1778
-
-
Silverman, E.K.1
Chapman, H.A.2
Drazen, J.M.3
-
5
-
-
38849132080
-
Clinical determinants of exacerbations in severe, early-onset COPD
-
Foreman MG, DeMeo DL, Hersh CP, et al. Clinical determinants of exacerbations in severe, early-onset COPD. Eur Respir J 2007; 30: 1124-1130.
-
(2007)
Eur Respir J
, vol.30
, pp. 1124-1130
-
-
Foreman, M.G.1
DeMeo, D.L.2
Hersh, C.P.3
-
6
-
-
34447537656
-
Decreased expression of antioxidant enzymes and increased expression of chemokines in COPD lung
-
Tomaki M, Sugiura H, Koarai A, et al. Decreased expression of antioxidant enzymes and increased expression of chemokines in COPD lung. Pulm Pharmacol Ther 2007; 20: 596-605.
-
(2007)
Pulm Pharmacol Ther
, vol.20
, pp. 596-605
-
-
Tomaki, M.1
Sugiura, H.2
Koarai, A.3
-
7
-
-
58849131079
-
Genetic variants of microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD
-
Chappell S, Daly L, Morgan K, et al. Genetic variants of microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD. Eur Respir J 2008; 32: 931-937.
-
(2008)
Eur Respir J
, vol.32
, pp. 931-937
-
-
Chappell, S.1
Daly, L.2
Morgan, K.3
-
8
-
-
0028295652
-
Human microsomal epoxide hydrolase: Genetic polymorphism and functional expression in vitro of amino acid variants
-
Hassett C, Aicher L, Sidhu JS, et al. Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants. Hum Mol Genet 1994; 3: 421-428.
-
(1994)
Hum Mol Genet
, vol.3
, pp. 421-428
-
-
Hassett, C.1
Aicher, L.2
Sidhu, J.S.3
-
9
-
-
0036554781
-
Coronary heart disease risk factors ranked by importance for the individual and community. A 21-year follow-up of 12,000 men and women from the Copenhagen City Heart Study
-
Schnohr P, Jensen JS, Scharling H, et al. Coronary heart disease risk factors ranked by importance for the individual and community. A 21-year follow-up of 12,000 men and women from The Copenhagen City Heart Study. Eur Heart J 2002; 23: 620-626.
-
(2002)
Eur Heart J
, vol.23
, pp. 620-626
-
-
Schnohr, P.1
Jensen, J.S.2
Scharling, H.3
-
10
-
-
34447511196
-
Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women
-
Nordestgaard BG, Benn M, Schnohr P, et al. Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA 2007; 298: 299-308.
-
(2007)
JAMA
, vol.298
, pp. 299-308
-
-
Nordestgaard, B.G.1
Benn, M.2
Schnohr, P.3
-
11
-
-
55549111247
-
Superoxide dismutase 3 polymorphism associated with reduced lung function in two large populations
-
Dahl M, Bowler RP, Juul K, et al. Superoxide dismutase 3 polymorphism associated with reduced lung function in two large populations. Am J Respir Crit Care Med 2008; 178: 906-912.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 906-912
-
-
Dahl, M.1
Bowler, R.P.2
Juul, K.3
-
12
-
-
67649884481
-
The expression of human microsomal epoxide hydrolase is predominantly driven by a genetically polymorphic far upstream promoter
-
Yang X, Liang SH, Weyant DM, et al. The expression of human microsomal epoxide hydrolase is predominantly driven by a genetically polymorphic far upstream promoter. J Pharmacol Exp Ther 2009; 330: 23-30.
-
(2009)
J Pharmacol Exp Ther
, vol.330
, pp. 23-30
-
-
Yang, X.1
Liang, S.H.2
Weyant, D.M.3
-
13
-
-
59649096813
-
No effects of EPHX1 polymorphisms on the level or change of FEV1 in the general population
-
Siedlinski M, Postma DS, Smit HA, et al. No effects of EPHX1 polymorphisms on the level or change of FEV1 in the general population. Eur Respir J 2009; 33: 446-449.
-
(2009)
Eur Respir J
, vol.33
, pp. 446-449
-
-
Siedlinski, M.1
Postma, D.S.2
Smit, H.A.3
-
14
-
-
0242323756
-
Genetic polymorphism of epoxide hydrolase and GSTM1 in chronic obstructive pulmonary disease
-
Park SS, Kim EJ, Son CY, et al. Genetic polymorphism of epoxide hydrolase and GSTM1 in chronic obstructive pulmonary disease. Tuberc Respir Dis 2003; 55: 88-97.
-
(2003)
Tuberc Respir Dis
, vol.55
, pp. 88-97
-
-
Park, S.S.1
Kim, E.J.2
Son, C.Y.3
-
15
-
-
0034011463
-
Genetic susceptibility to chronic obstructive pulmonary disease in Koreans: Combined analysis of polymorphic genotypes for microsomal epoxide hydrolase and glutathione S-transferase M1 and T1
-
Yim JJ, Park GY, Lee CT, et al. Genetic susceptibility to chronic obstructive pulmonary disease in Koreans: combined analysis of polymorphic genotypes for microsomal epoxide hydrolase and glutathione S-transferase M1 and T1. Thorax 2000; 55: 121-125.
-
(2000)
Thorax
, vol.55
, pp. 121-125
-
-
Yim, J.J.1
Park, G.Y.2
Lee, C.T.3
-
16
-
-
0034028105
-
Gene polymorphism for microsomal epoxide hydrolase and susceptibility to emphysema in a Japanese population
-
Takeyabu K, Yamaguchi E, Suzuki I, et al. Gene polymorphism for microsomal epoxide hydrolase and susceptibility to emphysema in a Japanese population. Eur Respir J 2000; 15: 891-894.
-
(2000)
Eur Respir J
, vol.15
, pp. 891-894
-
-
Takeyabu, K.1
Yamaguchi, E.2
Suzuki, I.3
-
17
-
-
2942620533
-
Relationship between polymorphisms of genes encoding microsomal epoxide hydrolase and glutathione S-transferase P1 and chronic obstructive pulmonary disease
-
Xiao D, Wang C, Du MJ, et al. Relationship between polymorphisms of genes encoding microsomal epoxide hydrolase and glutathione S-transferase P1 and chronic obstructive pulmonary disease. Chin Med J (Engl) 2004; 117: 661-667.
-
(2004)
Chin Med J (Engl)
, vol.117
, pp. 661-667
-
-
Xiao, D.1
Wang, C.2
Du, M.J.3
-
18
-
-
0036750035
-
Detection of polymorphisms at exons 3 (Tyr113 - >.His) and 4 (His139 - >.Arg) of the microsomal epoxide hydrolase gene using fluorescence PCR method combined with melting curves analysis
-
Rodriguez F, Jardi R, Costa X, et al. Detection of polymorphisms at exons 3 (Tyr113 - >.His) and 4 (His139 - >.Arg) of the microsomal epoxide hydrolase gene using fluorescence PCR method combined with melting curves analysis. Anal Biochem 2002; 308: 120-126.
-
(2002)
Anal Biochem
, vol.308
, pp. 120-126
-
-
Rodriguez, F.1
Jardi, R.2
Costa, X.3
-
19
-
-
11244252876
-
Genetic susceptibility for emphysematous changes of the lung in Japanese
-
Budhi A, Hiyama K, Isobe T, et al. Genetic susceptibility for emphysematous changes of the lung in Japanese. Int J Mol Med 2003; 11: 321-329.
-
(2003)
Int J Mol Med
, vol.11
, pp. 321-329
-
-
Budhi, A.1
Hiyama, K.2
Isobe, T.3
-
20
-
-
1542496457
-
Polymorphisms of the cytochrome P450 (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) genes in cystic fibrosis and chronic respiratory disease
-
Korytina GF, Yanbaeva DG, Viktorova TV. Polymorphisms of the cytochrome P450 (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) genes in cystic fibrosis and chronic respiratory disease. Mol Biol 2003; 37: 663-670.
-
(2003)
Mol Biol
, vol.37
, pp. 663-670
-
-
Korytina, G.F.1
Yanbaeva, D.G.2
Viktorova, T.V.3
-
21
-
-
0030849415
-
Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysema
-
Smith CA, Harrison DJ. Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysema. Lancet 1997; 350: 630-633.
-
(1997)
Lancet
, vol.350
, pp. 630-633
-
-
Smith, C.A.1
Harrison, D.J.2
-
22
-
-
34447136075
-
Microsomal epoxide hydrolase is not associated with COPD in a community-based sample
-
Matheson MC, Raven J, Walters EH, et al. Microsomal epoxide hydrolase is not associated with COPD in a community-based sample. Hum Biol 2006; 78: 705-717.
-
(2006)
Hum Biol
, vol.78
, pp. 705-717
-
-
Matheson, M.C.1
Raven, J.2
Walters, E.H.3
-
23
-
-
34249656273
-
Genetic polymorphisms of GSTP1 and mEPHX correlate with oxidative stress markers and lung function in COPD
-
Vibhuti A, Arif E, Deepak D, et al. Genetic polymorphisms of GSTP1 and mEPHX correlate with oxidative stress markers and lung function in COPD. Biochem Biophys Res Commun 2007; 359: 136-142.
-
(2007)
Biochem Biophys Res Commun
, vol.359
, pp. 136-142
-
-
Vibhuti, A.1
Arif, E.2
Deepak, D.3
-
24
-
-
43449100687
-
Glutathione S-transferase and microsomal epoxide hydrolase gene polymorphisms and risk of chronic obstructive pulmonary disease in Slovak population
-
Zidzik J, Slaba E, Joppa P, et al. Glutathione S-transferase and microsomal epoxide hydrolase gene polymorphisms and risk of chronic obstructive pulmonary disease in Slovak population. Croat Med J 2008; 49: 182-191.
-
(2008)
Croat Med J
, vol.49
, pp. 182-191
-
-
Zidzik, J.1
Slaba, E.2
Joppa, P.3
-
25
-
-
19644371310
-
Polymorphisms for microsomal epoxide hydrolase and genetic susceptibility to COPD
-
Park JY, Chen L, Wadhwa N, et al. Polymorphisms for microsomal epoxide hydrolase and genetic susceptibility to COPD. Int J Mol Med 2005; 15: 443-448.
-
(2005)
Int J Mol Med
, vol.15
, pp. 443-448
-
-
Park, J.Y.1
Chen, L.2
Wadhwa, N.3
-
26
-
-
3042695026
-
Genetic polymorphism of epoxide hydrolase and glutathione S-transferase in COPD
-
Cheng SL, Yu CJ, Chen CJ, et al. Genetic polymorphism of epoxide hydrolase and glutathione S-transferase in COPD. Eur Respir J 2004; 23: 818-824.
-
(2004)
Eur Respir J
, vol.23
, pp. 818-824
-
-
Cheng, S.L.1
Yu, C.J.2
Chen, C.J.3
-
27
-
-
33947715524
-
Relationship between COPD and polymorphisms of HOX-1 and mEPH in a Chinese population
-
Fu WP, Sun C, Dai LM, et al. Relationship between COPD and polymorphisms of HOX-1 and mEPH in a Chinese population. Oncol Rep 2007; 17: 483-488.
-
(2007)
Oncol Rep
, vol.17
, pp. 483-488
-
-
Fu, W.P.1
Sun, C.2
Dai, L.M.3
-
28
-
-
21844431677
-
Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations
-
Hersh CP, DeMeo DL, Lange C et al. Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations. Am J Respir Cell Mol Biol 2005; 33: 71-78.
-
(2005)
Am J Respir Cell Mol Biol
, vol.33
, pp. 71-78
-
-
Hersh, C.P.1
DeMeo, D.L.2
Lange, C.3
-
29
-
-
0035085353
-
Overestimated frequency of a possible emphysema-susceptibility allele when microsomal epoxide hydrolase is genotyped by the conventional polymerase chain reaction-based method
-
Keicho N, Emi M, Kajita M, et al. Overestimated frequency of a possible emphysema-susceptibility allele when microsomal epoxide hydrolase is genotyped by the conventional polymerase chain reaction-based method. J Hum Genet 2001; 46: 96-98.
-
(2001)
J Hum Genet
, vol.46
, pp. 96-98
-
-
Keicho, N.1
Emi, M.2
Kajita, M.3
-
30
-
-
33646338619
-
Genetically increased antioxidative protection and decreased chronic obstructive pulmonary disease
-
Juul K, Tybjaerg-Hansen A, Marklund S, et al. Genetically increased antioxidative protection and decreased chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2006; 173: 858-864.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 858-864
-
-
Juul, K.1
Tybjaerg-Hansen, A.2
Marklund, S.3
-
31
-
-
0037133110
-
Change in lung function and morbidity from chronic obstructive pulmonary disease in a1-antitrypsin MZ heterozygotes: A longitudinal study of the general population
-
Dahl M, Tybjaerg-Hansen A, Lange P, et al. Change in lung function and morbidity from chronic obstructive pulmonary disease in a1-antitrypsin MZ heterozygotes: A longitudinal study of the general population. Ann Intern Med 2002; 136: 270-279.
-
(2002)
Ann Intern Med
, vol.136
, pp. 270-279
-
-
Dahl, M.1
Tybjaerg-Hansen, A.2
Lange, P.3
-
32
-
-
73849097674
-
Surfactant protein-B 121ins2 heterozygosity, reduced pulmonary function, and chronic obstructive pulmonary disease in smokers
-
Baekvad-Hansen M, Dahl M, Tybjaerg-Hansen A, et al. Surfactant protein-B 121ins2 heterozygosity, reduced pulmonary function, and chronic obstructive pulmonary disease in smokers. Am J Respir Crit Care Med 2010; 181: 17-20.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. 17-20
-
-
Baekvad-Hansen, M.1
Dahl, M.2
Tybjaerg-Hansen, A.3
-
33
-
-
0035135566
-
Susceptibility genes for rapid decline of lung function in the lung health study
-
Sandford AJ, Chagani T, Weir TD, et al. Susceptibility genes for rapid decline of lung function in the lung health study. Am J Respir Crit Care Med 2001; 163: 469-473.
-
(2001)
Am J Respir Crit Care Med
, vol.163
, pp. 469-473
-
-
Sandford, A.J.1
Chagani, T.2
Weir, T.D.3
-
34
-
-
0033630306
-
Microsomal epoxide hydrolase genotypes and chronic obstructive pulmonary disease in Japanese
-
Yoshikawa M, Hiyama K, Ishioka S, et al. Microsomal epoxide hydrolase genotypes and chronic obstructive pulmonary disease in Japanese. Int J Mol Med 2000; 5: 49-53.
-
(2000)
Int J Mol Med
, vol.5
, pp. 49-53
-
-
Yoshikawa, M.1
Hiyama, K.2
Ishioka, S.3
-
35
-
-
33646251821
-
Genetic association analysis of functional impairment in chronic obstructive pulmonary disease
-
Hersh CP, DeMeo DL, Lazarus R, et al. Genetic association analysis of functional impairment in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2006; 173: 977-984.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 977-984
-
-
Hersh, C.P.1
DeMeo, D.L.2
Lazarus, R.3
-
36
-
-
51349096956
-
Association between polymorphisms of microsomal epoxide hydrolase and COPD: Results from meta-analyses
-
Hu G, Shi Z, Hu J, et al. Association between polymorphisms of microsomal epoxide hydrolase and COPD: results from meta-analyses. Respirology 2008; 13: 837-850.
-
(2008)
Respirology
, vol.13
, pp. 837-850
-
-
Hu, G.1
Shi, Z.2
Hu, J.3
-
37
-
-
70349449892
-
Meta-analyses on suspected chronic obstructive pulmonary disease genes: A summary of 20 years' research
-
Smolonska J, Wijmenga C, Postma DS, et al. Meta-analyses on suspected chronic obstructive pulmonary disease genes: a summary of 20 years' research. Am J Respir Crit Care Med 2009; 180: 618-631.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 618-631
-
-
Smolonska, J.1
Wijmenga, C.2
Postma, D.S.3
-
38
-
-
69349093790
-
Genetic variation of genes for xenobiotic-metabolizing enzymes and risk of bronchial asthma: The importance of gene-gene and gene-environment interactions for disease susceptibility
-
Polonikov AV, Ivanov VP, Solodilova MA. Genetic variation of genes for xenobiotic-metabolizing enzymes and risk of bronchial asthma: the importance of gene-gene and gene-environment interactions for disease susceptibility. J Hum Genet 2009; 54: 440-449.
-
(2009)
J Hum Genet
, vol.54
, pp. 440-449
-
-
Polonikov, A.V.1
Ivanov, V.P.2
Solodilova, M.A.3
-
39
-
-
53549112739
-
Genes in asthma: New genes and new ways
-
Moffatt MF. Genes in asthma: new genes and new ways. Curr Opin Allergy Clin Immunol 2008; 8: 411-417.
-
(2008)
Curr Opin Allergy Clin Immunol
, vol.8
, pp. 411-417
-
-
Moffatt, M.F.1
-
40
-
-
36749028129
-
Microsomal epoxide hydrolase, glutathione S-transferase P1, traffic and childhood asthma
-
Salam MT, Lin PC, Avol EL, et al. Microsomal epoxide hydrolase, glutathione S-transferase P1, traffic and childhood asthma. Thorax 2007; 62: 1050-1057.
-
(2007)
Thorax
, vol.62
, pp. 1050-1057
-
-
Salam, M.T.1
Lin, P.C.2
Avol, E.L.3
-
41
-
-
42749097422
-
Genetic architecture of transcript-level variation in humans
-
Duan S, Huang RS, Zhang W, et al. Genetic architecture of transcript-level variation in humans. Am J Hum Genet 2008; 82: 1101-1113.
-
(2008)
Am J Hum Genet
, vol.82
, pp. 1101-1113
-
-
Duan, S.1
Huang, R.S.2
Zhang, W.3
-
42
-
-
34547216747
-
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma
-
Moffatt MF, Kabesch M, Liang L, et al. Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 2007; 448: 470-473.
-
(2007)
Nature
, vol.448
, pp. 470-473
-
-
Moffatt, M.F.1
Kabesch, M.2
Liang, L.3
|