Avidity of influenza-specific memory CD8+ T-cell populations decays over time compromising antiviral immunity

European Journal of Immunology

Volumn 42, Issue 12, 2012, Pages 3235-3242

  Humphreys, Ian R ^a   Clement, Mathew ^a   Marsden, Morgan ^a   Ladell, Kristin ^a   Mclaren, James E ^a   Smart, Kathryn ^a   Hindley, James P ^a   Bridgeman, Hayley M ^a   van den Berg, Hugo A ^b   Price, David A ^a   Ager, Ann ^a   Wooldridge, Linda ^a   Godkin, Andrew ^a   Gallimore, Awen M ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

CD8+ T cell; Cytotoxicity; IFN ; Influenza; Vaccination

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; CD8+ T LYMPHOCYTE; CELL COUNT; CELL FUNCTION; CELL MIGRATION; CELL POPULATION; CONTROLLED STUDY; CYTOKINE RELEASE; DEGRANULATION; INFLUENZA; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; VIRUS IMMUNITY;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL DEGRANULATION; CELL MOVEMENT; CYTOKINES; IMMUNITY, CELLULAR; IMMUNOLOGIC MEMORY; INFLUENZAVIRUS A; MICE; ORTHOMYXOVIRIDAE INFECTIONS; TIME FACTORS;

EID: 84871339866     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201242575     Document Type: Article

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