The protective role of curcumin on perfluorooctane sulfonate-induced genotoxicity: Single cell gel electrophoresis and micronucleus test

Food and Chemical Toxicology

Volumn 53, Issue , 2013, Pages 249-255

  Çelik, Ayla ^a   Eke, Dilek ^a   Ekinci, Seda Yaprak ^a   Yildirim, Seda ^a  

^a MERSIN UNIVERSITY   (Turkey)

Author keywords

Curcumin; Micronucleus test; Perfluorooctane sulfonate; Single cell gel electrophoresis (SCGE: Comet assay)

Indexed keywords

CURCUMIN; PERFLUOROOCTANESULFONIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; COMET ASSAY; CONTROLLED STUDY; CURCUMA LONGA; CYTOTOXICITY; DNA DAMAGE; DOSE RESPONSE; DRUG STRUCTURE; ERYTHROCYTE; FEEDING; FEMALE; GEL ELECTROPHORESIS; GENOTOXICITY; IN VIVO STUDY; LD 50; MALE; MICRONUCLEUS TEST; NONHUMAN; PERENNIAL PLANT; PROTECTION; RAT; RHIZOME;

ALKANESULFONIC ACIDS; ANIMALS; COLORING AGENTS; COMET ASSAY; CURCUMA; CURCUMIN; DNA DAMAGE; ERYTHROCYTES; FLUOROCARBONS; MALE; MICRONUCLEUS TESTS; PLANT EXTRACTS; POLYPHENOLS; RATS; RATS, WISTAR;

CURCUMA LONGA; RATTUS;

EID: 84871989812     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.11.054     Document Type: Article

References (43)

1. Agarwal D.K., Chauhan L.K.S., Gupta S.K., Sundararaman V. Cytogenetic effects of deltametrin on rat bone marrow. Mutat. Res. 1994, 311:133-138.
2. Ak T., Gülçin I. Antioxidant and radical scavenging properties of curcumin. Chem. Biol. Interact. 2008, 174(1):27-37.
3. Ammon H.P., Wahl M.A. Pharmacology of Curcuma longa. Planta Med. 1991, 57(1):1-7.
4. Balakrishnan S., Vellaichamy L., Menon V.P., Manoharan S. Antigenotoxic effects of curcumin and piperine alone or in combination against 7,12 dimethylbenz(a)anthracene induced genotoxicity in bone marrow of golden Syrian hamsters. Toxicol. Mech. Methods 2008, 1-6.
5. Balu M., Sangeetha P., Murali G., Panneerselva C. Modulatory role of grape seed extract on age-related oxidative DNA damage in central nervous system of rats. Brain Res. Bull. 2006, 68:469-473.
6. Biswas S.K., McClure D., Jimenez L.A., Megson I.L., Rahman I. Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin- 8 release in alveolar epithelial cells: mechanism of free radical scavenging activity. Antioxid. Redox Signaling 2005, 7:32-41.
7. Governments unite to step-up reduction on global DDT reliance and add nine new chemicals under international treaty. Stockholm Convention Secretariat, Geneva, 8 May 2008. Available from: http://chm.pops.int/Convention/Pressrelease/COP4Geneva8May2009/tabid/542/language/en-US/Default.aspx.
8. 35S-labellede perfluorooctane sulfonate in adult mice after oral exposure to a low environmentally relevant dose or a high experimental dose. Toxicology 2011, 284:54-62.
9. Chattopadhyay I., Biswas K., Bandyopadhyay U., Banerjee R.K. Turmeric and curcumin: biological actions and medicinal applications. Curr. Sci. 2004, 87:44-53.
10. Collins A.R., Ma A.G., Duthie S.J. The kinetics of repair of oxidative DNA damage (strand breaks and oxidised pyrimidine) in human cells. Mutat. Res. 1995, 336:69-77.
11. Collins A., Dusinska M., Franklin M., Somorovska M., Petrovska H., Duthie S., Fillion L., Panayiotidis M., Raslova K., Vaughan N. Comet assay in human biomonitoring studies: reliability, validation, and applications. Environ. Mol. Mutagen. 1997, 30:139-146.
12. çavaş T. In vivo genotoxicity evaluation of atrazine and atrazine-based herbicide on fish Carassius auratus using the micronucleus test and the comet assay. Food Chem. Toxicol. 2011, 49:1431-1435.
13. çelik A., Mazmanci B., çamlica Y., Aşkin A., çömelekoĝlu Ü. Cytogenetic effects of lambda-cyhalothrin on Wistar rat bone marrow. Mutat. Res. 2003, 539:91-97.
14. çelik A., öĝenler O., çömelekoĝlu Ü. The evaluation of micronucleus frequency by acridine orange fluorescent staining in peripheral blood of rats treated with lead acetate. Mutagenesis 2005, 20(6):411-415.
15. çelik A., Kani{dotless}k A. Genotoxicity of occupational exposure towood dust: micronucleus frequency and nuclear changes in exfoliated buccal mucosa cells. Environ. Mol. Mutagen. 2006, 47:693-698.
16. EPA, 2002. Revised draft hazard assessment of perfluorooctanoic acid and its salts. US Environmental Protection Agency. Office of Pollution Prevention and Toxics. Risk Assessment Division (AR226-1136), Washington, DC, pp. 107.
17. Fang X., Feng Y., Wang J., Dai J. Perfluorononanoic acid-induced apoptosis in rat spleen involves oxidative stres and the activation of caspase-independent death pathway. Toxicology 2010, 267:54-59.
18. Fernández Freire P., Pérez Martin J.M., Herrero O., Peropadre A., de la Peña E., Hazen M.J. In vitro assessment of the cytotoxic and mutagenic potential of perfluorooctanoic acid. Toxicol. In Vitro 2008, 22:1228-1233.
19. Giesy J.P., Kannan K. Perfluorochemical surfactants in the environment. Environ. Sci. Technol. 2002, 36:147A-152A.
20. Hayashi M., Tice R.R., Macgregor J.T., Anderson D., Blakey D.H., Kirsch-Volders M., Oleson F.B., Pacchierotti F., Romagna F., Shimada H., Sutou S., Vannier B. In vivo rodent erythrocyte micronucleus assay. Mutat. Res. 1994, 312:293-304.
21. Joe B., Lokesh B.R. Role of capsaicin, curcumin and dietary M-3 fatty acids in lowering the generation of reactive oxygen species in rat peritoneal macrophages. Biochem. Biophys. Acta 1994, 1224:255-263.
22. Kim Woo-Keun, Lee Sung-Kyu, Jung J. Integrated assessment of biomarker responses in common carp (Cyprinus carpio) exposed to perfluorinated organic compounds. J. Hazard. Mater. 2010, 180:395-400.
23. Krishna G., Hayashi M. In vivo rodent micronucleus assay: protocol, conduct and data interpretation. Mutat. Res. 2000, 455:155-166.
24. Lee Hyung-Gyo, Lee Y.J., Yang Jae-Ho Perfluorooctane sulfonate induces apoptosis of cerebellar garnule cells via a ROS-dependent protein kinase C signaling pathway. Neurotoxicology 2012, 33:314-320.
25. Liu C., Yu K., Shi X., Wang J., Lam P.K.S., Wu R.S.S., Zhou B. Induction of oxidative stres and apoptosis by PFOS and PFOA in primary cultured hepatocytes of freshwater tilapia (Oreochromis niloticus). Aquat. Toxicol. 2007, 82:135-143.
26. Maheshwari R.K., Singh A.K., Gaddipati J., Srimal R.C. Multiple biological activities of curcumin: a short review. Life Sci. 2006, 78:2081-2087.
27. Masuda T., Maekawa T., Hidaka K., Bando H., Takeda Y., Yamaguchi H. Chemical studies on antioxidant mechanisms of curcumin: analysis of oxidative coupling products from curcumin and linoleate. J. Agric. Food Chem. 2001, 49:2539-2547.
28. Meyer O. Implications of animal welfare on toxicity testing. Hum. Exp. Toxicol. 1993, 12:516-521.
29. Miquel J., Bernd A., Sempere J.M., Díaz-Alperi J., Ramírez A. The curcuma antioxidants: pharmacological effects and prospects for future clinical use. A review. Arch. Gerontol. Geriatr. 2002, 34(1):37-46.
30. Narendra P.S. Rapid communication: a simple method for accurate estimation of apoptotic cells. Exp. Cell Res. 2000, 256:328-337.
31. OECD (Organisation for Economic Co-operation and Development), 2002. ENV/JM/RD(2002) 17/FINAL, Hazard assessment of perfluooroctane sulfonate (PFOS) and its salts.
32. Sankar P., Telang A.G., Manimaran A. Curcumin protects against cypermethrin-induced genotoxicity in rats. Environ. Toxicol. Pharmacol. 2010, 30:289-291.
33. Schmid W. Chemical mutagen testing on in vivo somatic mammalian cells. Agents Actions 1973, 3:77-85.
34. Sharma R.A., Gescher A.J., Steward W.P. Curcumin: the story so far. Eur. J. Cancer 2005, 41:1955-1968.
35. Siddique Y.H., Ara G., Beg T., Gupta J., Afzal M. Assessment of cell viability, lipid peroxidation and quantification of DNA fragmentation after the treatment of anticancerous drug mitomycin C and curcumin in cultured human blood lymphocytes. Exp. Toxicol. Pathol. 2010, 62:503-508.
36. Singh N.P., McCoy M.T., Tice R.R., Schneider E.L.A. Simple technique for quantitation of low levels of DNA damage in individuals cells. Exp. Cell Res. 1988, 175:184-191.
37. Sreejayan N., Rao M.N.A. Curcuminoids as potent inhibitors of lipid peroxidation. J. Pharm. Pharmacol. 1994, 46:1013-1016.
38. Sreejayan N., Rao M.N. Free radical scavenging activity of curcuminoids. Arzneimittelforschung 1996, 46:169-171.
39. Sreejayan N., Rao M.N. Nitric oxide scavenging by curcuminoids. J. Pharm. Pharmacol. 1997, 49:105-107.
40. Sun L.W., Qu M.M., Li Y.Q., Wu Y.L., Chen Y.G., Kong Z.M., Liu Z.T. Toxic effects of aminophenols on aquatic life using the zebrafish embriyo test and the comet assay. Bull. Contam. Toxicol. 2004, 73:628-634.
41. Tsuda S., Naonari M., Shunji U., Nobuyuki S., Yu F.S. The influence of antipoxidants on cigarette smoke-DNA single-strand breks in mouse organs: a preliminary study with the alkaline single cell gel electrophoresis assay. Toxicol. Sci. 2000, 54:104-109.
42. Yao X., Zhong L. Genotoxic risk and oxidative DNA damage in HepG2 cells exposed to perfluorooctanoic acid. Mutat. Res 2005, 10(1-2):38-44.
43. Ye X., Strynar M.J., Nakayama S.F., Varns J., Helfant L., Lazorchak J., Lindstrom A.B. Perfluorinated compounds in whole fish homogenates from the Ohio, Missouri, and Upper Mississippi Rivers, USA. Environ. Pollut. 2008, 156:1227-1232.