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Volumn 10, Issue 1, 2013, Pages 28-34

Quantitative analysis of peptides and proteins in biomedicine by targeted mass spectrometry

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDE; PROTEIN;

EID: 84871983086     PISSN: 15487091     EISSN: 15487105     Source Type: Journal    
DOI: 10.1038/nmeth.2309     Document Type: Review
Times cited : (393)

References (42)
  • 1
    • 0016584941 scopus 로고
    • The scope of mass spectrometry in clinical chemistry
    • Lawson, A.M. The scope of mass spectrometry in clinical chemistry. Clin. Chem. 21, 803-824 (1975).
    • (1975) Clin. Chem. , vol.21 , pp. 803-824
    • Lawson, A.M.1
  • 2
    • 0000376535 scopus 로고    scopus 로고
    • Peptide quantification by tandem mass spectrometry
    • Zhu, X. & Desiderio, D.M. Peptide quantification by tandem mass spectrometry. Mass Spectrom. Rev. 15, 213-240 (1996).
    • (1996) Mass Spectrom. Rev. , vol.15 , pp. 213-240
    • Zhu, X.1    Desiderio, D.M.2
  • 3
    • 80052539443 scopus 로고    scopus 로고
    • LC-MS/MS in the clinical laboratory-where to from here?
    • Grebe, S.K.G. & Singh, R.J.J. LC-MS/MS in the clinical laboratory - where to from here? Clin. Biochem. Rev. 32, 5-31 (2011).
    • (2011) Clin. Biochem. Rev. , vol.32 , pp. 5-31
    • Grebe, S.K.G.1    Singh, R.J.J.2
  • 4
    • 0001366599 scopus 로고
    • Triple quadrupole mass spectrometry for direct mixture analysis and structure elucidation
    • Yost, R.A. & Enke, C.G. Triple quadrupole mass spectrometry for direct mixture analysis and structure elucidation. Anal. Chem. 51, 1251-1264 (1979).
    • (1979) Anal. Chem. , vol.51 , pp. 1251-1264
    • Yost, R.A.1    Enke, C.G.2
  • 5
    • 84861990380 scopus 로고    scopus 로고
    • Selected reaction monitoring-based proteomics: Workflows, potential, pitfalls and future directions
    • Picotti, P. & Aebersold, R. Selected reaction monitoring-based proteomics: Workflows, potential, pitfalls and future directions. Nat. Methods 9, 555-566 (2012).
    • (2012) Nat. Methods , vol.9 , pp. 555-566
    • Picotti, P.1    Aebersold, R.2
  • 6
    • 10244256354 scopus 로고    scopus 로고
    • Isotope dilutionYmass spectrometric quantification of specific proteins: Model application with apolipoprotein A-I
    • Barr, J.R. et al. Isotope dilutionYmass spectrometric quantification of specific proteins: Model application with apolipoprotein A-I. Clin. Chem. 42, 1676-1682 (1996).
    • (1996) Clin. Chem. , vol.42 , pp. 1676-1682
    • Barr, J.R.1
  • 7
    • 0037795741 scopus 로고    scopus 로고
    • Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS
    • Gerber, S.A., Rush, J., Stemman, O., Kirschner, M.W. & Gygi, S.P. Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS. Proc. Natl. Acad. Sci. USA 100, 6940-6945 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 6940-6945
    • Gerber, S.A.1    Rush, J.2    Stemman, O.3    Kirschner, M.W.4    Gygi, S.P.5
  • 8
    • 38349068918 scopus 로고    scopus 로고
    • Quantitative multiplexed assays for low abundance proteins in plasma by targeted mass spectrometry and stable isotope dilution
    • Keshishian, H., Addona, T., Burgess, M., Kuhn, E. & Carr, S.A. Quantitative, multiplexed assays for low abundance proteins in plasma by targeted mass spectrometry and stable isotope dilution. Mol. Cell. Proteomics 6, 2212 (2007).
    • (2007) Mol. Cell. Proteomics , vol.6 , pp. 2212
    • Keshishian, H.1    Addona, T.2    Burgess, M.3    Kuhn, E.4    Carr, S.A.5
  • 9
    • 67650564834 scopus 로고    scopus 로고
    • Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma
    • Addona, T.A. et al. Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma. Nat. Biotechnol. 27, 633-641 (2009).
    • (2009) Nat. Biotechnol. , vol.27 , pp. 633-641
    • Addona, T.A.1
  • 10
    • 67649511917 scopus 로고    scopus 로고
    • Isotope dilution strategies for absolute quantitative proteomics
    • Brun, V., Masselon, C., Garin, J. & Dupuis, A. Isotope dilution strategies for absolute quantitative proteomics. J. Proteomics 72, 740-749 (2009).
    • (2009) J. Proteomics , vol.72 , pp. 740-749
    • Brun, V.1    Masselon, C.2    Garin, J.3    Dupuis, A.4
  • 11
    • 75749126208 scopus 로고    scopus 로고
    • Automated detection of inaccurate and imprecise transitions in quantitative assays of peptides by multiple monitoring mass spectrometry
    • Abbatiello, S.E., Mani, D.R., Keshishian, H. & Carr, S.A. Automated detection of inaccurate and imprecise transitions in quantitative assays of peptides by multiple monitoring mass spectrometry. Clin. Chem. 56, 291-305 (2010).
    • (2010) Clin. Chem. , vol.56 , pp. 291-305
    • Abbatiello, S.E.1    Mani, D.R.2    Keshishian, H.3    Carr, S.A.4
  • 12
    • 79955595074 scopus 로고    scopus 로고
    • MProphet: Automated data processing and statistical validation of large-scale SRM experiments
    • Reiter, L. et al. mProphet: Automated data processing and statistical validation of large-scale SRM experiments. Nat. Methods 8, 430-435 (2011).
    • (2011) Nat. Methods , vol.8 , pp. 430-435
    • Reiter, L.1
  • 13
    • 79960859298 scopus 로고    scopus 로고
    • A database of reaction monitoring mass spectrometry assays elucidating therapeutic response in cancer
    • Remily-Wood, E.R. et al. A database of reaction monitoring mass spectrometry assays elucidating therapeutic response in cancer. Proteomics Clin. Appl. 5, 383-396 (2011).
    • (2011) Proteomics Clin. Appl. , vol.5 , pp. 383-396
    • Remily-Wood, E.R.1
  • 14
    • 84863923380 scopus 로고    scopus 로고
    • Reproducible quantification of cancer-associated proteins in body fluids using targeted proteomics
    • Hüttenhain, R. et al. Reproducible quantification of cancer-associated proteins in body fluids using targeted proteomics. Sci. Transl. Med. 4, 142ra94 (2012).
    • (2012) Sci. Transl. Med. , vol.4
    • Hüttenhain, R.1
  • 15
    • 79960269601 scopus 로고    scopus 로고
    • A pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease
    • Addona, T.A. et al. A pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease. Nat. Biotechnol. 29, 635-643 (2011).
    • (2011) Nat. Biotechnol. , vol.29 , pp. 635-643
    • Addona, T.A.1
  • 16
    • 67449092269 scopus 로고    scopus 로고
    • Clinical quantitation of prostate-specific antigen biomarker in the low nanogram/milliliter range by conventional bore liquid chromatography-tandem mass spectrometry multiple reaction monitoring coupling and correlation with ELISA tests
    • Fortin, T. et al. Clinical quantitation of prostate-specific antigen biomarker in the low nanogram/milliliter range by conventional bore liquid chromatography-tandem mass spectrometry multiple reaction monitoring coupling and correlation with ELISA tests. Mol. Cell. Proteomics 8, 1006-1015 (2009).
    • (2009) Mol. Cell. Proteomics , vol.8 , pp. 1006-1015
    • Fortin, T.1
  • 17
    • 84866538934 scopus 로고    scopus 로고
    • Antibody-free targeted mass-spectrometric approach for quantification of proteins at low picogram per milliliter levels in human plasmaserum
    • Shi, T. et al. Antibody-free, targeted mass-spectrometric approach for quantification of proteins at low picogram per milliliter levels in human plasma/serum. Proc. Natl. Acad. Sci. USA 109, 15395-15400 (2012).
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 15395-15400
    • Shi, T.1
  • 18
    • 38849105619 scopus 로고    scopus 로고
    • Quantification of NTproBNP in rat serum using immunoprecipitation and LC/MS/MS: A biomarker of drug-induced cardiac hypertrophy
    • Berna, M.J. et al. Quantification of NTproBNP in rat serum using immunoprecipitation and LC/MS/MS: A biomarker of drug-induced cardiac hypertrophy. Anal. Chem. 80, 561-566 (2008).
    • (2008) Anal. Chem. , vol.80 , pp. 561-566
    • Berna, M.J.1
  • 19
    • 8844233567 scopus 로고    scopus 로고
    • Mass spectrometric quantitation of peptides and proteins using stable isotope standards and capture by anti-peptide antibodies (SISCAPA)
    • Anderson, N.L. et al. Mass spectrometric quantitation of peptides and proteins using stable isotope standards and capture by anti-peptide antibodies (SISCAPA). J. Proteome Res. 3, 235-244 (2004).
    • (2004) J. Proteome Res. , vol.3 , pp. 235-244
    • Anderson, N.L.1
  • 20
    • 79953305842 scopus 로고    scopus 로고
    • Evaluation of large scale quantitative proteomic assay development using peptide affinity-based mass spectrometry
    • M110.005645.
    • Whiteaker, J.R., et al. Evaluation of large scale quantitative proteomic assay development using peptide affinity-based mass spectrometry. Mol. Cell. Proteomics 10, M110.005645. (2011).
    • (2011) Mol. Cell. Proteomics , vol.10
    • Whiteaker, J.R.1
  • 21
    • 77956391635 scopus 로고    scopus 로고
    • Online high-flow peptide immunoaffinity enrichment and nanoflow LC-MS/MS: Assay development for total salivary pepsin/pepsinogen
    • Neubert, H., Gale, J. & Muirhead, D. Online high-flow peptide immunoaffinity enrichment and nanoflow LC-MS/MS: Assay development for total salivary pepsin/pepsinogen. Clin. Chem. 56, 1413-1423 (2010).
    • (2010) Clin. Chem. , vol.56 , pp. 1413-1423
    • Neubert, H.1    Gale, J.2    Muirhead, D.3
  • 22
    • 84862317182 scopus 로고    scopus 로고
    • Sequential multiplexed analyte quantification using peptide immunoaffinity enrichment coupled to mass spectrometry
    • M111.015347
    • Whiteaker, J.R. et al. Sequential multiplexed analyte quantification using peptide immunoaffinity enrichment coupled to mass spectrometry. Mol. Cell. Proteomics 11, M111.015347 (2012).
    • (2012) Mol. Cell. Proteomics , vol.11
    • Whiteaker, J.R.1
  • 23
    • 84860880032 scopus 로고    scopus 로고
    • Inter-laboratory evaluation of automated, multiplexed peptide immunoaffinity enrichment coupled to multiple reaction monitoring mass spectrometry for quantifying proteins in plasma
    • M111.013854.
    • Kuhn, E., et al. Inter-laboratory evaluation of automated, multiplexed peptide immunoaffinity enrichment coupled to multiple reaction monitoring mass spectrometry for quantifying proteins in plasma. Mol. Cell. Proteomics 11, M111.013854. (2012).
    • (2012) Mol. Cell. Proteomics , vol.11
    • Kuhn, E.1
  • 24
    • 63049109766 scopus 로고    scopus 로고
    • Immuno-MALDI-TOF MS: New perspectives for clinical applications of mass spectrometry
    • Sparbier, K. et al. Immuno-MALDI-TOF MS: New perspectives for clinical applications of mass spectrometry. Proteomics 9, 1442-1450 (2009).
    • (2009) Proteomics , vol.9 , pp. 1442-1450
    • Sparbier, K.1
  • 25
    • 33747030845 scopus 로고    scopus 로고
    • Protein biomarker discovery and validation: The long and uncertain path to clinical utility
    • Rifai, N., Gillette, M.A. & Carr, S.A. Protein biomarker discovery and validation: The long and uncertain path to clinical utility. Nat. Biotechnol. 971-983 (2006).
    • (2006) Nat. Biotechnol , pp. 971-983
    • Rifai, N.1    Gillette, M.A.2    Carr, S.A.3
  • 26
    • 75749130354 scopus 로고    scopus 로고
    • The clinical plasma proteome: A survey of clinical assays for proteins in plasma and serum
    • Anderson, N.L. The clinical plasma proteome: A survey of clinical assays for proteins in plasma and serum. Clin. Chem. 56, 177-185 (2010).
    • (2010) Clin. Chem. , vol.56 , pp. 177-185
    • Anderson, N.L.1
  • 27
    • 84858268381 scopus 로고    scopus 로고
    • Functional proteomics can define prognosis and predict pathologic complete response in patients with breast cancer
    • Gonzalez-Angulo, A.M. et al. Functional proteomics can define prognosis and predict pathologic complete response in patients with breast cancer. Clin. Proteomics 8, 11 (2011).
    • (2011) Clin. Proteomics , vol.8 , Issue.11
    • Gonzalez-Angulo, A.M.1
  • 29
    • 75749147077 scopus 로고    scopus 로고
    • Antibody-based protein multiplex platforms: Technical and operational challenges
    • Ellington, A.A., Kullo, I.J., Bailey, K.R. & Klee, G.G. Antibody-based protein multiplex platforms: Technical and operational challenges. Clin. Chem. 56, 186-193 (2010).
    • (2010) Clin. Chem. , vol.56 , pp. 186-193
    • Ellington, A.A.1    Kullo, I.J.2    Bailey, K.R.3    Klee, G.G.4
  • 30
    • 78649292703 scopus 로고    scopus 로고
    • High-content affinity-based proteomics: Unlocking protein biomarker discovery
    • Brody, E.N., Gold, L., Lawn, R.M., Walker, J.J. & Zichi, D. High-content affinity-based proteomics: Unlocking protein biomarker discovery. Expert Rev. Mol. Diagn. 10, 1013-1022 (2010).
    • (2010) Expert Rev. Mol. Diagn. , vol.10 , pp. 1013-1022
    • Brody, E.N.1    Gold, L.2    Lawn, R.M.3    Walker, J.J.4    Zichi, D.5
  • 31
    • 84871417805 scopus 로고    scopus 로고
    • Aptamers and the next generation of diagnostic reagents
    • advance online publication 23 October 2012 doi:10.1002/prca.201200042
    • Thiviyanathan, V. & Gorenstein, D.G. Aptamers and the next generation of diagnostic reagents. Proteomics Clin. Appl. advance online publication 23 October 2012 (doi:10.1002/prca.201200042).
    • Proteomics Clin. Appl.
    • Thiviyanathan, V.1    Gorenstein, D.G.2
  • 32
    • 75749095246 scopus 로고    scopus 로고
    • The bottleneck in the cancer biomarker pipeline and protein quantification through mass spectrometryYbased approaches: Current strategies for candidate verification
    • Makawita, S. & Diamandis, E.P. The bottleneck in the cancer biomarker pipeline and protein quantification through mass spectrometryYbased approaches: Current strategies for candidate verification. Clin. Chem. 56, 212-222 (2010).
    • (2010) Clin. Chem. , vol.56 , pp. 212-222
    • Makawita, S.1    Diamandis, E.P.2
  • 33
    • 84863276025 scopus 로고    scopus 로고
    • Mass spectrometry in biomarker applications: From untargeted discovery to targeted verification, and implications for platform convergence and clinical application
    • Smith, R.D. Mass spectrometry in biomarker applications: From untargeted discovery to targeted verification, and implications for platform convergence and clinical application. Clin. Chem. 58, 528-530 (2012).
    • (2012) Clin. Chem. , vol.58 , pp. 528-530
    • Smith, R.D.1
  • 34
    • 84865584319 scopus 로고    scopus 로고
    • Comparison of standard-flow and nano-flow liquid chromatography systems for MRM-based quantitation of putative plasma biomarker proteins
    • Percy, A.J., Chambers, A.G., Yang, J., Domanski, D. & Borchers, C.H. Comparison of standard-flow and nano-flow liquid chromatography systems for MRM-based quantitation of putative plasma biomarker proteins. Anal. Bioanal. Chem. 404, 1089-1101 (2012).
    • (2012) Anal. Bioanal. Chem. , vol.404 , pp. 1089-1101
    • Percy, A.J.1    Chambers, A.G.2    Yang, J.3    Domanski, D.4    Borchers, C.H.5
  • 35
    • 79960214321 scopus 로고    scopus 로고
    • A targeted proteomics-based pipeline for verification of biomarkers in plasma
    • Whiteaker, J.R. et al. A targeted proteomics-based pipeline for verification of biomarkers in plasma. Nat. Biotechnol. 29, 625-634 (2011).
    • (2011) Nat. Biotechnol. , vol.29 , pp. 625-634
    • Whiteaker, J.R.1
  • 36
    • 84860869256 scopus 로고    scopus 로고
    • MRM-based multiplexed quantitation of 67 putative cardiovascular disease biomarkers in human plasma
    • Domanski, D. et al. MRM-based multiplexed quantitation of 67 putative cardiovascular disease biomarkers in human plasma. Proteomics 12, 1222-1243 (2012).
    • (2012) Proteomics , vol.12 , pp. 1222-1243
    • Domanski, D.1
  • 37
    • 84857847927 scopus 로고    scopus 로고
    • Multiplex targeted proteomic assay for biomarker detection in plasma: A pancreatic cancer biomarker case study
    • Pan, S. et al. Multiplex targeted proteomic assay for biomarker detection in plasma: A pancreatic cancer biomarker case study. J. Proteome Res. 11, 1937-1948 (2012).
    • (2012) J. Proteome Res. , vol.11 , pp. 1937-1948
    • Pan, S.1
  • 38
    • 79952284442 scopus 로고    scopus 로고
    • Mutant proteins as cancer-specific biomarkers
    • Wang, Q. et al. Mutant proteins as cancer-specific biomarkers. Proc. Natl. Acad. Sci. USA 108, 2444-2449 (2011).
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 2444-2449
    • Wang, Q.1
  • 39
    • 55349139657 scopus 로고    scopus 로고
    • Quantification of thyroglobulin, a low-abundance serum protein, by immunoaffinity peptide enrichment and tandem mass spectrometry
    • Hoofnagle, A.N., Becker, J.O., Wener, M.H. & Heinecke, J.W. Quantification of thyroglobulin, a low-abundance serum protein, by immunoaffinity peptide enrichment and tandem mass spectrometry. Clin. Chem. 54, 1796-1804 (2008).
    • (2008) Clin. Chem. , vol.54 , pp. 1796-1804
    • Hoofnagle, A.N.1    Becker, J.O.2    Wener, M.H.3    Heinecke, J.W.4
  • 40
    • 55049104915 scopus 로고    scopus 로고
    • Accurate inclusion mass screening: A bridge from unbiased discovery to targeted assay development for biomarker verifications
    • Jaffe, J.D. et al. Accurate inclusion mass screening: A bridge from unbiased discovery to targeted assay development for biomarker verification. Mol. Cell. Proteomics 7, 1952-1962 (2008).
    • (2008) Mol. Cell. Proteomics , vol.7 , pp. 1952-1962
    • Jaffe, J.D.1
  • 41
    • 84861860481 scopus 로고    scopus 로고
    • Targeted data extraction of the MS/MS spectra generated by data independent acquisition: A new concept for consistent and accurate proteome analysis
    • Gillet, L.C. et al. Targeted data extraction of the MS/MS spectra generated by data independent acquisition: A new concept for consistent and accurate proteome analysis. Mol. Cell. Proteomics 11, 1-17 (2012).
    • (2012) Mol. Cell. Proteomics , vol.11 , pp. 1-17
    • Gillet, L.C.1
  • 42
    • 84870656540 scopus 로고    scopus 로고
    • Targeted proteomic quantification on quadrupole Orbitrap mass spectrometer
    • Proteomics advance online publication 7 September 2012 doi:10.1074/mcp.O112.019802
    • Gallien, S. et al. Targeted proteomic quantification on quadrupole Orbitrap mass spectrometer. Mol. Cell. Proteomics advance online publication 7 September 2012 (doi:10.1074/mcp.O112.019802).
    • Mol. Cell.
    • Gallien, S.1


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