Quantification of NTproBNP in rat serum using immunoprecipitation and LC/MS/MS: A biomarker of drug-induced cardiac hypertrophy

Analytical Chemistry

Volumn 80, Issue 3, 2008, Pages 561-566

  Berna, Michael ^a   Ott, Lee ^a   Engle, Steve ^a   Watson, David ^a   Solter, Philip ^b   Ackermann, Bradley ^a  

^a ELI LILLY AND COMPANY   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIAC HYPERTROPHY; IMMUNOPRECIPITATION;

CARDIOVASCULAR SURGERY; DRUG PRODUCTS; MAGNETIC RESONANCE IMAGING; RATS;

BIOMARKERS;

AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; BIOLOGICAL MARKER; BRAIN NATRIURETIC PEPTIDE; LEUCYLLEUCYLGLUTAMYLLEUCYLISOLEUCINE; LEUCYLLEUCYLGLUTAMYLLEUCYLISOLEUCYLARGININE; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY AFFINITY; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DISEASE MARKER; DRUG INDUCED DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART FAILURE; HEART HYPERTROPHY; HEART LEFT VENTRICLE; HEART WEIGHT; IMMUNOPRECIPITATION; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PEPTIDE SYNTHESIS; PRESSURE MEASUREMENT; QUANTITATIVE ANALYSIS; RAT; SOLID PHASE EXTRACTION; VALIDATION PROCESS;

AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL MARKERS; CARDIOMYOPATHY, HYPERTROPHIC; CHROMATOGRAPHY, LIQUID; DISEASE MODELS, ANIMAL; HUMANS; IMMUNOPRECIPITATION; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; NATRIURETIC PEPTIDE, BRAIN; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 38849105619     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac702311m     Document Type: Article

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