-
1
-
-
36849078044
-
Progression-free survival is a surrogate for survival in advanced colorectal cancer
-
Buyse M, Burzykowski T, Carroll K, Michiels S, Sargent DJ, Miller LL, et al. Progression-free survival is a surrogate for survival in advanced colorectal cancer. J Clin Oncol 2007;25:5218-24.
-
(2007)
J Clin Oncol
, vol.25
, pp. 5218-5224
-
-
Buyse, M.1
Burzykowski, T.2
Carroll, K.3
Michiels, S.4
Sargent, D.J.5
Miller, L.L.6
-
2
-
-
77953243023
-
Surrogate endpoints for overall survival in digestive oncology trials: Which candidates? A questionnaires survey among clinicians and methodologists
-
Methy N, Bedenne L, Bonnetain F. Surrogate endpoints for overall survival in digestive oncology trials: which candidates? A questionnaires survey among clinicians and methodologists. BMC Cancer 2010;10:277.
-
(2010)
BMC Cancer
, vol.10
, pp. 277
-
-
Methy, N.1
Bedenne, L.2
Bonnetain, F.3
-
3
-
-
47249152394
-
Endpoints and surrogate endpoints in colorectal cancer: A review of recent developments
-
Piedbois P, Buyse M. Endpoints and surrogate endpoints in colorectal cancer: a review of recent developments. Curr Opin Oncol 2008;20:466-71.
-
(2008)
Curr Opin Oncol
, vol.20
, pp. 466-471
-
-
Piedbois, P.1
Buyse, M.2
-
4
-
-
52649094924
-
Surrogate endpoints for overall survival in advanced colorectal cancer: A clinician's perspective
-
Piedbois P, Miller Croswell J. Surrogate endpoints for overall survival in advanced colorectal cancer: a clinician's perspective. Stat Methods Med Res 2008;17:519-27.
-
(2008)
Stat Methods Med Res
, vol.17
, pp. 519-527
-
-
Piedbois, P.1
Miller Croswell, J.2
-
5
-
-
77949321968
-
Progression-free survival as surrogate and as true end point: Insights from the breast and colorectal cancer literature
-
Saad ED, Katz A, Hoff PM, Buyse M. Progression-free survival as surrogate and as true end point: insights from the breast and colorectal cancer literature. Ann Oncol 2010;21:7-12.
-
(2010)
Ann Oncol
, vol.21
, pp. 7-12
-
-
Saad, E.D.1
Katz, A.2
Hoff, P.M.3
Buyse, M.4
-
6
-
-
35649022759
-
Surrogate end points for median overall survival in metastatic colorectal cancer: Literature-based analysis from 39 randomized controlled trials of first-line chemotherapy
-
Tang PA, Bentzen SM, Chen EX, Siu LL. Surrogate end points for median overall survival in metastatic colorectal cancer: literature-based analysis from 39 randomized controlled trials of first-line chemotherapy. J Clin Oncol 2007;25:4562-8.
-
(2007)
J Clin Oncol
, vol.25
, pp. 4562-4568
-
-
Tang, P.A.1
Bentzen, S.M.2
Chen, E.X.3
Siu, L.L.4
-
7
-
-
80053467288
-
Progression-free survival as a primary endpoint in clinical trials of metastatic colorectal cancer
-
Gill S, Berry S, Biagi J, Butts C, Buyse M, Chen E, et al. Progression-free survival as a primary endpoint in clinical trials of metastatic colorectal cancer. Curr Oncol 2011;18(Suppl 2):S5-S10.
-
(2011)
Curr Oncol
, vol.18
, Issue.SUPPL. 2
-
-
Gill, S.1
Berry, S.2
Biagi, J.3
Butts, C.4
Buyse, M.5
Chen, E.6
-
8
-
-
84864004759
-
Overall survival: Patient outcome, therapeutic objective, clinical trial end point, or public health measure?
-
Saad ED, Buyse M. Overall survival: patient outcome, therapeutic objective, clinical trial end point, or public health measure? J Clin Oncol 2012;30:1750-4.
-
(2012)
J Clin Oncol
, vol.30
, pp. 1750-1754
-
-
Saad, E.D.1
Buyse, M.2
-
9
-
-
84860496547
-
Progression-free survival: Meaningful or simply measurable?
-
Booth CM, Eisenhauer EA. Progression-free survival: meaningful or simply measurable? J Clin Oncol 2012;30:1030-3.
-
(2012)
J Clin Oncol
, vol.30
, pp. 1030-1033
-
-
Booth, C.M.1
Eisenhauer, E.A.2
-
10
-
-
2142703727
-
Survival of patients with advanced colorectal cancer improves with the availability of fluorouracil-leucovorin, irinotecan, and oxaliplatin in the course of treatment
-
Grothey A, Sargent D, Goldberg RM, Schmoll H-J. Survival of patients with advanced colorectal cancer improves with the availability of fluorouracil-leucovorin, irinotecan, and oxaliplatin in the course of treatment. J Clin Oncol 2004;22:1209-14.
-
(2004)
J Clin Oncol
, vol.22
, pp. 1209-1214
-
-
Grothey, A.1
Sargent, D.2
Goldberg, R.M.3
Schmoll, H.-J.4
-
11
-
-
0030268577
-
Surrogate end points in clinical trials: Are we being misled?
-
Fleming TR, DeMets DL. Surrogate end points in clinical trials: are we being misled? Ann Intern Med 1996;125:605-13.
-
(1996)
Ann Intern Med
, vol.125
, pp. 605-613
-
-
Fleming, T.R.1
DeMets, D.L.2
-
12
-
-
0037986306
-
End points and United States Food and Drug Administration approval of oncology drugs
-
Johnson JR, Williams G, Pazdur R. End points and United States Food and Drug Administration approval of oncology drugs. J Clin Oncol 2003;21:1404-11.
-
(2003)
J Clin Oncol
, vol.21
, pp. 1404-1411
-
-
Johnson, J.R.1
Williams, G.2
Pazdur, R.3
-
13
-
-
0024520844
-
Surrogate endpoints in clinical trials: Definition and operational criteria
-
Prentice RL. Surrogate endpoints in clinical trials: definition and operational criteria. Stat Med 1989;8:431-40.
-
(1989)
Stat Med
, vol.8
, pp. 431-440
-
-
Prentice, R.L.1
-
14
-
-
60749096036
-
Surrogate and mediating endpoints: Current status and future directions
-
Prentice RL. Surrogate and mediating endpoints: current status and future directions. J Natl Cancer Inst 2009;101:216-7.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 216-217
-
-
Prentice, R.L.1
-
15
-
-
0022393322
-
Food and Drug Administration requirements for approval of new anticancer drugs
-
Johnson JR, Temple R. Food and Drug Administration requirements for approval of new anticancer drugs. Cancer Treat Rep 1985;69:1155-9.
-
(1985)
Cancer Treat Rep
, vol.69
, pp. 1155-1159
-
-
Johnson, J.R.1
Temple, R.2
-
16
-
-
0031708453
-
Criteria for the validation of surrogate endpoints in randomized experiments
-
Buyse M, Molenberghs G. Criteria for the validation of surrogate endpoints in randomized experiments. Biometrics 1998;54:1014-29.
-
(1998)
Biometrics
, vol.54
, pp. 1014-1029
-
-
Buyse, M.1
Molenberghs, G.2
-
17
-
-
0001863948
-
The validation of surrogate endpoints in meta-analyses of randomized experiments
-
Buyse M, Molenberghs G, Burzykowski T, Renard D, Geys H. The validation of surrogate endpoints in meta-analyses of randomized experiments. Biostatistics 2000;1:49-67.
-
(2000)
Biostatistics
, vol.1
, pp. 49-67
-
-
Buyse, M.1
Molenberghs, G.2
Burzykowski, T.3
Renard, D.4
Geys, H.5
-
18
-
-
0026573094
-
Statistical validation of intermediate endpoints for chronic diseases
-
Freedman LS, Graubard BI, Schatzkin A. Statistical validation of intermediate endpoints for chronic diseases. Stat Med 1992;11:167-78.
-
(1992)
Stat Med
, vol.11
, pp. 167-178
-
-
Freedman, L.S.1
Graubard, B.I.2
Schatzkin, A.3
-
19
-
-
61649098633
-
Progression-free survival and time to progression as primary end points in advanced breast cancer: Often used, sometimes loosely defined
-
Saad ED, Katz A. Progression-free survival and time to progression as primary end points in advanced breast cancer: often used, sometimes loosely defined. Ann Oncol 2009;20:460-4.
-
(2009)
Ann Oncol
, vol.20
, pp. 460-464
-
-
Saad, E.D.1
Katz, A.2
-
20
-
-
77951936254
-
Monoclonal antibodies in the treatment of metastatic colorectal cancer: A review
-
Tol J, Punt CJ. Monoclonal antibodies in the treatment of metastatic colorectal cancer: a review. Clin Ther 2010;32:437-53.
-
(2010)
Clin Ther
, vol.32
, pp. 437-453
-
-
Tol, J.1
Punt, C.J.2
-
21
-
-
68049122102
-
Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
-
Moher D, Liberati A, Tetzlaff J, Altman DG, The PG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med 2009;6:e1000097.
-
(2009)
PLoS Med
, vol.6
-
-
Moher, D.1
Liberati, A.2
Tetzlaff, J.3
Altman, D.G.4
The, P.G.5
-
22
-
-
77951642723
-
Overall survival and post-progression survival in advanced breast cancer: A review of recent randomized clinical trials
-
Saad ED, Katz A, Buyse M. Overall survival and post-progression survival in advanced breast cancer: a review of recent randomized clinical trials. J Clin Oncol 2010;28:1958-62.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1958-1962
-
-
Saad, E.D.1
Katz, A.2
Buyse, M.3
-
23
-
-
84862986717
-
Meta-analysis of the association between progression-free survival and overall survival in metastatic colorectal cancer
-
Chirila C, Odom D, Devercelli G, Khan S, Sherif BN, Kaye JA, et al. Meta-analysis of the association between progression-free survival and overall survival in metastatic colorectal cancer. Int J Colorectal Dis 2012;27:623-34.
-
(2012)
Int J Colorectal Dis
, vol.27
, pp. 623-634
-
-
Chirila, C.1
Odom, D.2
Devercelli, G.3
Khan, S.4
Sherif, B.N.5
Kaye, J.A.6
-
24
-
-
0035648331
-
Validation of surrogate end points in multiple randomized clinical trials with failure time end points
-
Burzykowski T, Molenberghs G, Buyse M, Geys H, Renard D. Validation of surrogate end points in multiple randomized clinical trials with failure time end points. J R Stat Soc: Ser C (Appl Stat) 2001;50:405-22.
-
(2001)
J R Stat Soc: ser C (Appl Stat)
, vol.50
, pp. 405-422
-
-
Burzykowski, T.1
Molenberghs, G.2
Buyse, M.3
Geys, H.4
Renard, D.5
-
25
-
-
84858860230
-
Meta-analysis for surrogacy: Accelerated failure time models and semicompeting risks modeling
-
Ghosh D, Taylor JM, Sargent DJ. Meta-analysis for surrogacy: accelerated failure time models and semicompeting risks modeling. Biometrics 2012;68:226-32.
-
(2012)
Biometrics
, vol.68
, pp. 226-232
-
-
Ghosh, D.1
Taylor, J.M.2
Sargent, D.J.3
-
26
-
-
0028927937
-
Calculating correlation coefficients with repeated observations: Part 2 - Correlation between subjects
-
Bland JM, Altman DG. Calculating correlation coefficients with repeated observations: part 2 - correlation between subjects. BMJ 1995;310:633.
-
(1995)
BMJ
, vol.310
, pp. 633
-
-
Bland, J.M.1
Altman, D.G.2
-
27
-
-
0028926373
-
Statistics notes: Calculating correlation coefficients with repeated observations: part 1 - Correlation within subjects
-
Bland JM, Altman DG. Statistics notes: calculating correlation coefficients with repeated observations: part 1 - correlation within subjects. BMJ 1995;310:446.
-
(1995)
BMJ
, vol.310
, pp. 446
-
-
Bland, J.M.1
Altman, D.G.2
-
28
-
-
0035871538
-
Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: Results of a randomized phase III study
-
Hoff PM, Ansari R, Batist G, Cox J, Kocha W, Kuperminc M, et al. Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: results of a randomized phase III study. J Clin Oncol 2001;19:2282-92.
-
(2001)
J Clin Oncol
, vol.19
, pp. 2282-2292
-
-
Hoff, P.M.1
Ansari, R.2
Batist, G.3
Cox, J.4
Kocha, W.5
Kuperminc, M.6
-
29
-
-
0035503151
-
Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: Results of a large phase III study
-
Van Cutsem E, Twelves C, Cassidy J, Allman D, Bajetta E, Boyer M, et al. Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: results of a large phase III study. J Clin Oncol 2001;19:4097-106.
-
(2001)
J Clin Oncol
, vol.19
, pp. 4097-4106
-
-
Van Cutsem, E.1
Twelves, C.2
Cassidy, J.3
Allman, D.4
Bajetta, E.5
Boyer, M.6
-
30
-
-
17744418861
-
Randomized phase III study of high-dose fluorouracil given as a weekly 24-hour infusion with or without leucovorin versus bolus fluorouracil plus leucovorin in advanced colorectal cancer: European organization of Research and Treatment of Cancer Gastrointestinal Group Study 40952
-
Kohne CH, Wils J, Lorenz M, Schoffski P, Voigtmann R, Bokemeyer C, et al. Randomized phase III study of high-dose fluorouracil given as a weekly 24-hour infusion with or without leucovorin versus bolus fluorouracil plus leucovorin in advanced colorectal cancer: European organization of Research and Treatment of Cancer Gastrointestinal Group Study 40952. J Clin Oncol 2003;21:3721-8.
-
(2003)
J Clin Oncol
, vol.21
, pp. 3721-3728
-
-
Kohne, C.H.1
Wils, J.2
Lorenz, M.3
Schoffski, P.4
Voigtmann, R.5
Bokemeyer, C.6
-
31
-
-
0034712536
-
Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: A multicentre randomised trial
-
Douillard JY, Cunningham D, Roth AD, Navarro M, James RD, Karasek P, et al. Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial. Lancet 2000;355:1041-7.
-
(2000)
Lancet
, vol.355
, pp. 1041-1047
-
-
Douillard, J.Y.1
Cunningham, D.2
Roth, A.D.3
Navarro, M.4
James, R.D.5
Karasek, P.6
-
32
-
-
0034727063
-
Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group
-
Saltz LB, Cox JV, Blanke C, Rosen LS, Fehrenbacher L, Moore MJ, et al. Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group.NEngl JMed 2000;343:905-14.
-
(2000)
NEngl JMed
, vol.343
, pp. 905-914
-
-
Saltz, L.B.1
Cox, J.V.2
Blanke, C.3
Rosen, L.S.4
Fehrenbacher, L.5
Moore, M.J.6
-
33
-
-
24644432555
-
Phase III study of weekly high-dose infusional fluorouracil plus folinic acid with or without irinotecan in patients with metastatic colorectal cancer: European Organisation for Research and Treatment of Cancer Gastrointestinal Group Study 40986
-
Kohne CH, van Cutsem E, Wils J, Bokemeyer C, El-Serafi M, Lutz MP, et al. Phase III study of weekly high-dose infusional fluorouracil plus folinic acid with or without irinotecan in patients with metastatic colorectal cancer: European Organisation for Research and Treatment of Cancer Gastrointestinal Group Study 40986. J Clin Oncol 2005;23:4856-65.
-
(2005)
J Clin Oncol
, vol.23
, pp. 4856-4865
-
-
Kohne, C.H.1
Van Cutsem, E.2
Wils, J.3
Bokemeyer, C.4
El-Serafi, M.5
Lutz, M.P.6
-
34
-
-
60549103258
-
Randomized study of weekly irinotecan plus high-dose 5-fluorouracil (FUIRI) versus biweekly irinotecan plus 5-fluorouracil/leucovorin (FOLFIRI) as first-line chemotherapy for patients with metastatic colorectal cancer: A Spanish Cooperative Group for the Treatment of Digestive Tumors Study
-
Aranda E, Valladares M, Martinez-Villacampa M, Benavides M, Gomez A, Massutti B, et al. Randomized study of weekly irinotecan plus high-dose 5-fluorouracil (FUIRI) versus biweekly irinotecan plus 5-fluorouracil/leucovorin (FOLFIRI) as first-line chemotherapy for patients with metastatic colorectal cancer: a Spanish Cooperative Group for the Treatment of Digestive Tumors Study. Ann Oncol 2009;20:251-7.
-
(2009)
Ann Oncol
, vol.20
, pp. 251-257
-
-
Aranda, E.1
Valladares, M.2
Martinez-Villacampa, M.3
Benavides, M.4
Gomez, A.5
Massutti, B.6
-
35
-
-
43049109526
-
A randomized phase III multicenter trial comparing irinotecan in combination with the Nordic bolus 5-FU and folinic acid schedule or the bolus/infused de Gramont schedule (Lv5FU2) in patients with metastatic colorectal cancer
-
Glimelius B, Sorbye H, Balteskard L, Bystrom P, Pfeiffer P, Tveit K, et al. A randomized phase III multicenter trial comparing irinotecan in combination with the Nordic bolus 5-FU and folinic acid schedule or the bolus/infused de Gramont schedule (Lv5FU2) in patients with metastatic colorectal cancer. Ann Oncol 2008;19:909-14.
-
(2008)
Ann Oncol
, vol.19
, pp. 909-914
-
-
Glimelius, B.1
Sorbye, H.2
Balteskard, L.3
Bystrom, P.4
Pfeiffer, P.5
Tveit, K.6
-
36
-
-
79955506636
-
Intermittent versus continuous chemotherapy in advanced colorectal cancer: A randomised 'GISCAD' trial
-
Labianca R, Sobrero A, Isa L, Cortesi E, Barni S, Nicolella D, et al. Intermittent versus continuous chemotherapy in advanced colorectal cancer: a randomised 'GISCAD' trial. Ann Oncol 2011;22:1236-42.
-
(2011)
Ann Oncol
, vol.22
, pp. 1236-1242
-
-
Labianca, R.1
Sobrero, A.2
Isa, L.3
Cortesi, E.4
Barni, S.5
Nicolella, D.6
-
37
-
-
0033989203
-
Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracil-leucovorin as first-line treatment of metastatic colorectal cancer
-
Giacchetti S, Perpoint B, Zidani R, Le Bail N, Faggiuolo R, Focan C, et al. Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracil-leucovorin as first-line treatment of metastatic colorectal cancer. J Clin Oncol 2000;18:136-47.
-
(2000)
J Clin Oncol
, vol.18
, pp. 136-147
-
-
Giacchetti, S.1
Perpoint, B.2
Zidani, R.3
Le Bail, N.4
Faggiuolo, R.5
Focan, C.6
-
38
-
-
0033874892
-
Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
-
de Gramont A, Figer A, Seymour M, Homerin M, Hmissi A, Cassidy J, et al. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol 2000;18:2938-47.
-
(2000)
J Clin Oncol
, vol.18
, pp. 2938-2947
-
-
De Gramont, A.1
Figer, A.2
Seymour, M.3
Homerin, M.4
Hmissi, A.5
Cassidy, J.6
-
39
-
-
0001120708
-
Phase III study of bolus 5-fluorouracil (5-FU)/folinic acid (FA) (Mayo) vs weekly high-dose 24h 5-FU infusion/FA + oxaliplatin (OXA) (FUFOX) in advanced colorectal cancer (ACRC)
-
abstr 512
-
Grothey A, Deschler B, Kroening H, Ridwelski K, Reichardt P, Kretzschmar A, et al. Phase III study of bolus 5-fluorouracil (5-FU)/folinic acid (FA) (Mayo) vs weekly high-dose 24h 5-FU infusion/FA + oxaliplatin (OXA) (FUFOX) in advanced colorectal cancer (ACRC). Proc Am Soc Clin Oncol 21: 2002 (abstr 512).
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
-
-
Grothey, A.1
Deschler, B.2
Kroening, H.3
Ridwelski, K.4
Reichardt, P.5
Kretzschmar, A.6
-
40
-
-
77949324847
-
A randomized study comparing short-time infusion of oxaliplatin in combination with capecitabine XELOX(30) and chronomodulated XELOX(30) as first-line therapy in patients with advanced colorectal cancer
-
Qvortrup C, Jensen BV, Fokstuen T, Nielsen SE, Keldsen N, Glimelius B, et al. A randomized study comparing short-time infusion of oxaliplatin in combination with capecitabine XELOX(30) and chronomodulated XELOX(30) as first-line therapy in patients with advanced colorectal cancer. Ann Oncol 2010;21:87-91.
-
(2010)
Ann Oncol
, vol.21
, pp. 87-91
-
-
Qvortrup, C.1
Jensen, B.V.2
Fokstuen, T.3
Nielsen, S.E.4
Keldsen, N.5
Glimelius, B.6
-
41
-
-
34948892881
-
Phase III study of capecitabine plus oxaliplatin compared with continuous-infusion fluorouracil plus oxaliplatin as first-line therapy in metastatic colorectal cancer: Final report of the Spanish Cooperative Group for the Treatment of Digestive Tumors Trial
-
Diaz-Rubio E, Tabernero J, Gomez-Espana A, Massuti B, Sastre J, Chaves M, et al. Phase III study of capecitabine plus oxaliplatin compared with continuous-infusion fluorouracil plus oxaliplatin as first-line therapy in metastatic colorectal cancer: final report of the Spanish Cooperative Group for the Treatment of Digestive Tumors Trial. J Clin Oncol 2007;25:4224-30.
-
(2007)
J Clin Oncol
, vol.25
, pp. 4224-4230
-
-
Diaz-Rubio, E.1
Tabernero, J.2
Gomez-Espana, A.3
Massuti, B.4
Sastre, J.5
Chaves, M.6
-
42
-
-
60649088752
-
Two different first-line 5-fluorouracil regimens with or without oxaliplatin in patients with metastatic colorectal cancer
-
Cunningham D, Sirohi B, Pluzanska A, Utracka-Hutka B, Zaluski J, Glynne-Jones R, et al. Two different first-line 5-fluorouracil regimens with or without oxaliplatin in patients with metastatic colorectal cancer. Ann Oncol 2009;20:244-50.
-
(2009)
Ann Oncol
, vol.20
, pp. 244-250
-
-
Cunningham, D.1
Sirohi, B.2
Pluzanska, A.3
Utracka-Hutka, B.4
Zaluski, J.5
Glynne-Jones, R.6
-
43
-
-
33644843853
-
OPTIMOX1: A randomized study of FOLFOX4 or FOLFOX7 with oxaliplatin in a stop-and-Go fashion in advanced colorectal cancer - A GERCOR study
-
Tournigand C, Cervantes A, Figer A, Lledo G, Flesch M, Buyse M, et al. OPTIMOX1: a randomized study of FOLFOX4 or FOLFOX7 with oxaliplatin in a stop-and-Go fashion in advanced colorectal cancer - a GERCOR study. J Clin Oncol 2006;24:394-400.
-
(2006)
J Clin Oncol
, vol.24
, pp. 394-400
-
-
Tournigand, C.1
Cervantes, A.2
Figer, A.3
Lledo, G.4
Flesch, M.5
Buyse, M.6
-
44
-
-
33747060772
-
Phase III trial comparing 4-day chronomodulated therapy versus 2-day conventional delivery of fluorouracil, leucovorin, and oxaliplatin as first-line chemotherapy of metastatic colorectal cancer: The European Organisation for Research and Treatment of Cancer Chronotherapy Group
-
Giacchetti S, Bjarnason G, Garufi C, Genet D, Iacobelli S, Tampellini M, et al. Phase III trial comparing 4-day chronomodulated therapy versus 2-day conventional delivery of fluorouracil, leucovorin, and oxaliplatin as first-line chemotherapy of metastatic colorectal cancer: the European Organisation for Research and Treatment of Cancer Chronotherapy Group. J Clin Oncol 2006;24:3562-9.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3562-3569
-
-
Giacchetti, S.1
Bjarnason, G.2
Garufi, C.3
Genet, D.4
Iacobelli, S.5
Tampellini, M.6
-
45
-
-
33644681094
-
Randomised Phase III study of biweekly 24-h infusion of high-dose 5FU with folinic acid and oxaliplatin versus monthly plus 5-FU/folinic acid in first-line treatment of advanced colorectal cancer
-
Hospers GA, Schaapveld M, Nortier JW, Wils J, van Bochove A, de Jong RS, et al. Randomised Phase III study of biweekly 24-h infusion of high-dose 5FU with folinic acid and oxaliplatin versus monthly plus 5-FU/folinic acid in first-line treatment of advanced colorectal cancer. Ann Oncol 2006;17:443-9.
-
(2006)
Ann Oncol
, vol.17
, pp. 443-449
-
-
Hospers, G.A.1
Schaapveld, M.2
Nortier, J.W.3
Wils, J.4
Van Bochove, A.5
De Jong, R.S.6
-
46
-
-
34948857445
-
Phase III study of capecitabine plus oxaliplatin compared with fluorouracil and leucovorin plus oxaliplatin in metastatic colorectal cancer: A final report of the AIO Colorectal Study Group
-
Porschen R, Arkenau HT, Kubicka S, Greil R, Seufferlein T, Freier W, et al. Phase III study of capecitabine plus oxaliplatin compared with fluorouracil and leucovorin plus oxaliplatin in metastatic colorectal cancer: a final report of the AIO Colorectal Study Group. J Clin Oncol 2007;25:4217-23.
-
(2007)
J Clin Oncol
, vol.25
, pp. 4217-4223
-
-
Porschen, R.1
Arkenau, H.T.2
Kubicka, S.3
Greil, R.4
Seufferlein, T.5
Freier, W.6
-
47
-
-
78649873169
-
Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil/leucovorin plus oxaliplatin (FOLFOX-6) as first-line treatment for metastatic colorectal cancer
-
Ducreux M, Bennouna J, Hebbar M, Ychou M, Lledo G, Conroy T, et al. Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil/leucovorin plus oxaliplatin (FOLFOX-6) as first-line treatment for metastatic colorectal cancer. Int J Cancer 2011;128:682-90.
-
(2011)
Int J Cancer
, vol.128
, pp. 682-690
-
-
Ducreux, M.1
Bennouna, J.2
Hebbar, M.3
Ychou, M.4
Lledo, G.5
Conroy, T.6
-
48
-
-
80053384385
-
Sequential versus combination chemotherapy for the treatment of advanced colorectal cancer (FFCD 2000-05): An open-label, randomised, phase 3 trial
-
Ducreux M, Malka D, Mendiboure J, Etienne PL, Texereau P, Auby D, et al. Sequential versus combination chemotherapy for the treatment of advanced colorectal cancer (FFCD 2000-05): an open-label, randomised, phase 3 trial. Lancet Oncol 2011;12:1032-44.
-
(2011)
Lancet Oncol
, vol.12
, pp. 1032-1044
-
-
Ducreux, M.1
Malka, D.2
Mendiboure, J.3
Etienne, P.L.4
Texereau, P.5
Auby, D.6
-
49
-
-
79959740774
-
XELOX vs FOLFOX-4 as first-line therapy for metastatic colorectal cancer: NO16966 updated results
-
Cassidy J, Clarke S, Diaz-Rubio E, Scheithauer W, Figer A, Wong R, et al. XELOX vs FOLFOX-4 as first-line therapy for metastatic colorectal cancer: NO16966 updated results. Br J Cancer 2011;105:58-64.
-
(2011)
Br J Cancer
, vol.105
, pp. 58-64
-
-
Cassidy, J.1
Clarke, S.2
Diaz-Rubio, E.3
Scheithauer, W.4
Figer, A.5
Wong, R.6
-
50
-
-
1342290189
-
FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: A randomized GERCOR study
-
Tournigand C, Andre T, Achille E, Lledo G, Flesh M, Mery-Mignard D, et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol 2004;22:229-37.
-
(2004)
J Clin Oncol
, vol.22
, pp. 229-237
-
-
Tournigand, C.1
Andre, T.2
Achille, E.3
Lledo, G.4
Flesh, M.5
Mery-Mignard, D.6
-
51
-
-
24644457747
-
Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: A multicenter study of the Gruppo Oncologico Dell'Italia Meridionale
-
Colucci G, Gebbia V, Paoletti G, Giuliani F, Caruso M, Gebbia N, et al. Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: a multicenter study of the Gruppo Oncologico Dell'Italia Meridionale. J Clin Oncol 2005;23:4866-75.
-
(2005)
J Clin Oncol
, vol.23
, pp. 4866-4875
-
-
Colucci, G.1
Gebbia, V.2
Paoletti, G.3
Giuliani, F.4
Caruso, M.5
Gebbia, N.6
-
52
-
-
21344459245
-
Oxaliplatin plus high-dose folinic acid and 5-fluorouracil i.v. bolus (OXAFAFU) versus irinotecan plus high-dose folinic acid and 5-fluorouracil i.v. bolus (IRIFAFU) in patients with metastatic colorectal carcinoma: A Southern Italy Cooperative Oncology Group phase III trial
-
Comella P, Massidda B, Filippelli G, Palmeri S, Natale D, Farris A, et al. Oxaliplatin plus high-dose folinic acid and 5-fluorouracil i.v. bolus (OXAFAFU) versus irinotecan plus high-dose folinic acid and 5-fluorouracil i.v. bolus (IRIFAFU) in patients with metastatic colorectal carcinoma: a Southern Italy Cooperative Oncology Group phase III trial. Ann Oncol 2005;16:878-86.
-
(2005)
Ann Oncol
, vol.16
, pp. 878-886
-
-
Comella, P.1
Massidda, B.2
Filippelli, G.3
Palmeri, S.4
Natale, D.5
Farris, A.6
-
53
-
-
34447255724
-
Different strategies of sequential and combination chemotherapy for patients with poor prognosis advanced colorectal cancer (MRC FOCUS): A randomised controlled trial
-
Seymour MT, Maughan TS, Ledermann JA, Topham C, James R, Gwyther SJ, et al. Different strategies of sequential and combination chemotherapy for patients with poor prognosis advanced colorectal cancer (MRC FOCUS): a randomised controlled trial. Lancet 2007;370:143-52.
-
(2007)
Lancet
, vol.370
, pp. 143-152
-
-
Seymour, M.T.1
Maughan, T.S.2
Ledermann, J.A.3
Topham, C.4
James, R.5
Gwyther, S.J.6
-
54
-
-
34447277453
-
Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): A phase III randomised controlled trial
-
Koopman M, Antonini NF, Douma J, Wals J, Honkoop AH, Erdkamp FL, et al. Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): a phase III randomised controlled trial. Lancet 2007;370:135-42.
-
(2007)
Lancet
, vol.370
, pp. 135-142
-
-
Koopman, M.1
Antonini, N.F.2
Douma, J.3
Wals, J.4
Honkoop, A.H.5
Erdkamp, F.L.6
-
55
-
-
78650683300
-
Phase III trial of irinotecan plus infusional 5-fluorouracil/folinic acid versus irinotecan plus oxaliplatin as first-line treatment of advanced colorectal cancer
-
Fischer von Weikersthal L, Schalhorn A, Stauch M, Quietzsch D, Maubach PA, Lambertz H, et al. Phase III trial of irinotecan plus infusional 5-fluorouracil/folinic acid versus irinotecan plus oxaliplatin as first-line treatment of advanced colorectal cancer. Eur J Cancer 2011;47:206-14.
-
(2011)
Eur J Cancer
, vol.47
, pp. 206-214
-
-
Fischer Von Weikersthal, L.1
Schalhorn, A.2
Stauch, M.3
Quietzsch, D.4
Maubach, P.A.5
Lambertz, H.6
-
56
-
-
1842569206
-
A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer
-
Goldberg RM, Sargent DJ, Morton RF, Fuchs CS, Ramanathan RK, Williamson SK, et al. A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 2004;22:23-30.
-
(2004)
J Clin Oncol
, vol.22
, pp. 23-30
-
-
Goldberg, R.M.1
Sargent, D.J.2
Morton, R.F.3
Fuchs, C.S.4
Ramanathan, R.K.5
Williamson, S.K.6
-
57
-
-
34547097252
-
Updated efficacy and toxicity analysis of irinotecan and oxaliplatin (IROX): Intergroup trial N9741 in first-line treatment of metastatic colorectal cancer
-
Ashley AC, Sargent DJ, Alberts SR, Grothey A, Campbell ME, Morton RF, et al. Updated efficacy and toxicity analysis of irinotecan and oxaliplatin (IROX): intergroup trial N9741 in first-line treatment of metastatic colorectal cancer. Cancer 2007;110:670-7.
-
(2007)
Cancer
, vol.110
, pp. 670-677
-
-
Ashley, A.C.1
Sargent, D.J.2
Alberts, S.R.3
Grothey, A.4
Campbell, M.E.5
Morton, R.F.6
-
58
-
-
33645309877
-
FOLFOXIRI (folinic acid, 5-fluorouracil, oxaliplatin and irinotecan) vs FOLFIRI (folinic acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): A multicentre randomised phase III trial from the Hellenic Oncology Research Group (HORG)
-
Souglakos J, Androulakis N, Syrigos K, Polyzos A, Ziras N, Athanasiadis A, et al. FOLFOXIRI (folinic acid, 5-fluorouracil, oxaliplatin and irinotecan) vs FOLFIRI (folinic acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): a multicentre randomised phase III trial from the Hellenic Oncology Research Group (HORG). Br J Cancer 2006;94:798-805.
-
(2006)
Br J Cancer
, vol.94
, pp. 798-805
-
-
Souglakos, J.1
Androulakis, N.2
Syrigos, K.3
Polyzos, A.4
Ziras, N.5
Athanasiadis, A.6
-
59
-
-
34249000361
-
Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: The Gruppo Oncologico Nord Ovest
-
Falcone A, Ricci S, Brunetti I, Pfanner E, Allegrini G, Barbara C, et al. Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: the Gruppo Oncologico Nord Ovest. J Clin Oncol 2007;25:1670-6.
-
(2007)
J Clin Oncol
, vol.25
, pp. 1670-1676
-
-
Falcone, A.1
Ricci, S.2
Brunetti, I.3
Pfanner, E.4
Allegrini, G.5
Barbara, C.6
-
60
-
-
78651297593
-
Randomized trial of two induction chemotherapy regimens in metastatic colorectal cancer: An updated analysis
-
Masi G, Vasile E, Loupakis F, Cupini S, Fornaro L, Baldi G, et al. Randomized trial of two induction chemotherapy regimens in metastatic colorectal cancer: an updated analysis. J Natl Cancer Inst 2011;103:21-30.
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 21-30
-
-
Masi, G.1
Vasile, E.2
Loupakis, F.3
Cupini, S.4
Fornaro, L.5
Baldi, G.6
-
61
-
-
20544478429
-
Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: Results of a randomized phase II trial
-
Kabbinavar FF, Schulz J, McCleod M, Patel T, Hamm JT, Hecht JR, et al. Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: results of a randomized phase II trial. J Clin Oncol 2005;23:3697-705.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3697-3705
-
-
Kabbinavar, F.F.1
Schulz, J.2
McCleod, M.3
Patel, T.4
Hamm, J.T.5
Hecht, J.R.6
-
62
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W, Cartwright T, Hainsworth J, Heim W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004;350:2335-42.
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
-
63
-
-
42949149159
-
Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: A randomized phase III study
-
Saltz LB, Clarke S, Diaz-Rubio E, Scheithauer W, Figer A, Wong R, et al. Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. J Clin Oncol 2008;26:2013-9.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2013-2019
-
-
Saltz, L.B.1
Clarke, S.2
Diaz-Rubio, E.3
Scheithauer, W.4
Figer, A.5
Wong, R.6
-
64
-
-
77955232505
-
Efficacy and safety of bevacizumab (BEV)-based combination regimens in patients with metastatic colorectal cancer (mCRC): Randomized phase II study of BEV + FOLFIRI versus BEV + XELIRI (FNCLCC ACCORD 13/0503 study)
-
abstr 4086
-
Ducreux M, Adenis A, Mendiboure J, Francois E, Boucher E, Chauffert B, et al. Efficacy and safety of bevacizumab (BEV)-based combination regimens in patients with metastatic colorectal cancer (mCRC): randomized phase II study of BEV + FOLFIRI versus BEV + XELIRI (FNCLCC ACCORD 13/0503 study). J Clin Oncol 27:15s, 2009 (suppl; abstr 4086).
-
(2009)
J Clin Oncol
, vol.27
, Issue.SUPPL.
-
-
Ducreux, M.1
Adenis, A.2
Mendiboure, J.3
Francois, E.4
Boucher, E.5
Chauffert, B.6
-
65
-
-
77955497309
-
Capecitabine, bevacizumab and mitomycin in first-line treatment of metastatic colorectal cancer: Results of the Australasian Gastrointestinal Trials Group Randomized, Phase III MAX Study
-
Tebbutt NC, Wilson K, Gebski VJ, Cummins MM, Zannino D, van Hazel GA, et al. Capecitabine, bevacizumab and mitomycin in first-line treatment of metastatic colorectal cancer: results of the Australasian Gastrointestinal Trials Group Randomized, Phase III MAX Study. J Clin Oncol 2010;28:3191-8.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3191-3198
-
-
Tebbutt, N.C.1
Wilson, K.2
Gebski, V.J.3
Cummins, M.M.4
Zannino, D.5
Van Hazel, G.A.6
-
66
-
-
84856304557
-
First-line XELOX plus bevacizumab followed by XELOX plus bevacizumab or single-agent bevacizumab as maintenance therapy in patients with metastatic colorectal cancer: The phase III MACRO TTD study
-
Diaz-Rubio E, Gomez-Espana A, Massuti B, Sastre J, Abad A, Valladares M, et al. First-line XELOX plus bevacizumab followed by XELOX plus bevacizumab or single-agent bevacizumab as maintenance therapy in patients with metastatic colorectal cancer: the phase III MACRO TTD study. Oncologist 2012;17:15-25.
-
(2012)
Oncologist
, vol.17
, pp. 15-25
-
-
Diaz-Rubio, E.1
Gomez-Espana, A.2
Massuti, B.3
Sastre, J.4
Abad, A.5
Valladares, M.6
-
67
-
-
84862991983
-
XELIRI-bevacizumab versus FOLFIRI-bevacizumab as first-line treatment in patients with metastatic colorectal cancer: A Hellenic Cooperative Oncology Group phase III trial with collateral biomarker analysis
-
Pectasides D, Papaxoinis G, Kalogeras K, Eleftheraki A, Xanthakis I, Makatsoris T, et al. XELIRI-bevacizumab versus FOLFIRI-bevacizumab as first-line treatment in patients with metastatic colorectal cancer: a Hellenic Cooperative Oncology Group phase III trial with collateral biomarker analysis. BMC Cancer 2012;12:271.
-
(2012)
BMC Cancer
, vol.12
, pp. 271
-
-
Pectasides, D.1
Papaxoinis, G.2
Kalogeras, K.3
Eleftheraki, A.4
Xanthakis, I.5
Makatsoris, T.6
-
68
-
-
80054779014
-
Efficacy and safety of bevacizumab plus chemotherapy in Chinese patients with metastatic colorectal cancer: A randomized phase III ARTIST trial
-
Guan ZZ, Xu JM, Luo RC, Feng FY, Wang LW, Shen L, et al. Efficacy and safety of bevacizumab plus chemotherapy in Chinese patients with metastatic colorectal cancer: a randomized phase III ARTIST trial. Chin J Cancer 2011;30:682-9.
-
(2011)
Chin J Cancer
, vol.30
, pp. 682-689
-
-
Guan, Z.Z.1
Xu, J.M.2
Luo, R.C.3
Feng, F.Y.4
Wang, L.W.5
Shen, L.6
-
69
-
-
84856435741
-
Randomised phase-II trial of CAPIRI (capecitabine, irinotecan) plus bevacizumab vs FOLFIRI (folinic acid, 5-fluorouracil, irinotecan) plus bevacizumab as first-line treatment of patients with unresectable/metastatic colorectal cancer (mCRC)
-
Souglakos J, Ziras N, Kakolyris S, Boukovinas I, Kentepozidis N, Makrantonakis P, et al. Randomised phase-II trial of CAPIRI (capecitabine, irinotecan) plus bevacizumab vs FOLFIRI (folinic acid, 5-fluorouracil, irinotecan) plus bevacizumab as first-line treatment of patients with unresectable/metastatic colorectal cancer (mCRC). Br J Cancer 2012;106:453-9.
-
(2012)
Br J Cancer
, vol.106
, pp. 453-459
-
-
Souglakos, J.1
Ziras, N.2
Kakolyris, S.3
Boukovinas, I.4
Kentepozidis, N.5
Makrantonakis, P.6
-
70
-
-
79956298812
-
Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: Updated analysis of overall survival according to tumor KRAS and BRAF mutation status
-
Van Cutsem E, Kohne CH, Lang I, Folprecht G, Nowacki MP, Cascinu S, et al. Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor KRAS and BRAF mutation status. J Clin Oncol 2011;29:2011-9.
-
(2011)
J Clin Oncol
, vol.29
, pp. 2011-2019
-
-
Van Cutsem, E.1
Kohne, C.H.2
Lang, I.3
Folprecht, G.4
Nowacki, M.P.5
Cascinu, S.6
-
71
-
-
78649745934
-
Identification of potentially responsive subsets when cetuximab is added to oxaliplatin-fluoropyrimidine chemotherapy (CT) in first-line advanced colorectal cancer (aCRC): Mature results of the MRC COIN trial
-
abstr 3502
-
Maughan TS, Adams R, Smith CG, Seymour MT, Wilson RH, Meade AM, et al. Identification of potentially responsive subsets when cetuximab is added to oxaliplatin-fluoropyrimidine chemotherapy (CT) in first-line advanced colorectal cancer (aCRC): mature results of the MRC COIN trial. J Clin Oncol 28:15s, 2010 (suppl; abstr 3502).
-
(2010)
J Clin Oncol
, vol.28
, Issue.SUPPL.
-
-
Maughan, T.S.1
Adams, R.2
Smith, C.G.3
Seymour, M.T.4
Wilson, R.H.5
Meade, A.M.6
-
72
-
-
79959571031
-
Intermittent versus continuous oxaliplatin and fluoropyrimidine combination chemotherapy for first-line treatment of advanced colorectal cancer: Results of the randomised phase 3 MRC COIN trial
-
Adams RA, Meade AM, Seymour MT, Wilson RH, Madi A, Fisher D, et al. Intermittent versus continuous oxaliplatin and fluoropyrimidine combination chemotherapy for first-line treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial. Lancet Oncol 2011;12:642-53.
-
(2011)
Lancet Oncol
, vol.12
, pp. 642-653
-
-
Adams, R.A.1
Meade, A.M.2
Seymour, M.T.3
Wilson, R.H.4
Madi, A.5
Fisher, D.6
-
73
-
-
59949091448
-
Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer
-
Bokemeyer C, Bondarenko I, Makhson A, Hartmann JT, Aparicio J, de Braud F, et al. Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer. J Clin Oncol 2009;27:663-71.
-
(2009)
J Clin Oncol
, vol.27
, pp. 663-671
-
-
Bokemeyer, C.1
Bondarenko, I.2
Makhson, A.3
Hartmann, J.T.4
Aparicio, J.5
De Braud, F.6
-
74
-
-
59949102930
-
A randomized phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer
-
Hecht JR, Mitchell E, Chidiac T, Scroggin C, Hagenstad C, Spigel D, et al. A randomized phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer. J Clin Oncol 2009;27:672-80.
-
(2009)
J Clin Oncol
, vol.27
, pp. 672-680
-
-
Hecht, J.R.1
Mitchell, E.2
Chidiac, T.3
Scroggin, C.4
Hagenstad, C.5
Spigel, D.6
-
75
-
-
84860785653
-
Phase III trial of cetuximab, bevacizumab, and 5-fluorouracil/leucovorin vs. FOLFOX-bevacizumab in colorectal cancer
-
Saltz L, Badarinath S, Dakhil S, Bienvenu B, Harker WG, Birchfield G, et al. Phase III trial of cetuximab, bevacizumab, and 5-fluorouracil/leucovorin vs. FOLFOX-bevacizumab in colorectal cancer. Clin Colorectal Cancer 2012;11:101-11.
-
(2012)
Clin Colorectal Cancer
, vol.11
, pp. 101-111
-
-
Saltz, L.1
Badarinath, S.2
Dakhil, S.3
Bienvenu, B.4
Harker, W.G.5
Birchfield, G.6
-
76
-
-
59749091477
-
Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer
-
Tol J, Koopman M, Cats A, Rodenburg CJ, Creemers GJ, Schrama JG, et al. Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer. N Engl J Med 2009;360:563-72.
-
(2009)
N Engl J Med
, vol.360
, pp. 563-572
-
-
Tol, J.1
Koopman, M.2
Cats, A.3
Rodenburg, C.J.4
Creemers, G.J.5
Schrama, J.G.6
-
77
-
-
79956310674
-
Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: The OPUS study
-
Bokemeyer C, Bondarenko I, Hartmann JT, de Braud F, Schuch G, Zubel A, et al. Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. Ann Oncol 2011;22:1535-46.
-
(2011)
Ann Oncol
, vol.22
, pp. 1535-1546
-
-
Bokemeyer, C.1
Bondarenko, I.2
Hartmann, J.T.3
De Braud, F.4
Schuch, G.5
Zubel, A.6
-
78
-
-
78149250536
-
Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: The PRIME study
-
Douillard JY, Siena S, Cassidy J, Tabernero J, Burkes R, Barugel M, et al. Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study. J Clin Oncol 2010;28:4697-705.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4697-4705
-
-
Douillard, J.Y.1
Siena, S.2
Cassidy, J.3
Tabernero, J.4
Burkes, R.5
Barugel, M.6
-
79
-
-
63849088630
-
Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
-
Van Cutsem E, Kohne CH, Hitre E, Zaluski J, Chang Chien CR, Makhson A, et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med 2009;360:1408-17.
-
(2009)
N Engl J Med
, vol.360
, pp. 1408-1417
-
-
Van Cutsem, E.1
Kohne, C.H.2
Hitre, E.3
Zaluski, J.4
Chang Chien, C.R.5
Makhson, A.6
-
80
-
-
77954372574
-
Cetuximab plus FOLFOX6 or FOLFIRI in metastatic colorectal cancer: CECOG trial
-
Ocvirk J, Brodowicz T, Wrba F, Ciuleanu TE, Kurteva G, Beslija S, et al. Cetuximab plus FOLFOX6 or FOLFIRI in metastatic colorectal cancer: CECOG trial. World J Gastroenterol 2010;16:3133-43.
-
(2010)
World J Gastroenterol
, vol.16
, pp. 3133-3143
-
-
Ocvirk, J.1
Brodowicz, T.2
Wrba, F.3
Ciuleanu, T.E.4
Kurteva, G.5
Beslija, S.6
-
81
-
-
79959337678
-
Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: Results of the randomised phase 3 MRC COIN trial
-
Maughan TS, Adams RA, Smith CG, Meade AM, Seymour MT, Wilson RH, et al. Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial. Lancet 2011;377:2103-14.
-
(2011)
Lancet
, vol.377
, pp. 2103-2114
-
-
Maughan, T.S.1
Adams, R.A.2
Smith, C.G.3
Meade, A.M.4
Seymour, M.T.5
Wilson, R.H.6
-
82
-
-
79952768031
-
Cetuximab plus capecitabine and irinotecan compared with cetuximab plus capecitabine and oxaliplatin as first-line treatment for patients with metastatic colorectal cancer: AIO KRK-0104 - A randomized trial of the German AIO CRC study group
-
Moosmann N, von Weikersthal LF, Vehling-Kaiser U, Stauch M, Hass HG, Dietzfelbinger H, et al. Cetuximab plus capecitabine and irinotecan compared with cetuximab plus capecitabine and oxaliplatin as first-line treatment for patients with metastatic colorectal cancer: AIO KRK-0104 - a randomized trial of the German AIO CRC study group. J Clin Oncol 2011;29:1050-8.
-
(2011)
J Clin Oncol
, vol.29
, pp. 1050-1058
-
-
Moosmann, N.1
Von Weikersthal, L.F.2
Vehling-Kaiser, U.3
Stauch, M.4
Hass, H.G.5
Dietzfelbinger, H.6
-
83
-
-
79952153189
-
LBA20 - Randomized phase III study of 5-fluorouracil/folinate/oxaliplatin given continuously or intermittently with or without cetuximab, as first-line treatment of metastatic colorectal cancer: The nordic VII study (NCT00145314), by the Nordic Colorectal Cancer Biomodulation Group
-
Tveit K, Guren T, Glimelius B, Pfeiffer P, Sorbye H, Pyrhonen S, et al. LBA20 - randomized phase III study of 5-fluorouracil/folinate/oxaliplatin given continuously or intermittently with or without cetuximab, as first-line treatment of metastatic colorectal cancer: the nordic VII study (NCT00145314), by the Nordic Colorectal Cancer Biomodulation Group. Ann Oncol ESMO 2010 late-breaking abstracts LBA 20. 2010;21(Suppl 8):LBA20.
-
(2010)
Ann Oncol ESMO 2010 Late-breaking Abstracts LBA 20
, vol.21
, Issue.SUPPL. 8
-
-
Tveit, K.1
Guren, T.2
Glimelius, B.3
Pfeiffer, P.4
Sorbye, H.5
Pyrhonen, S.6
-
84
-
-
84861198824
-
Biologic therapies in the metastatic colorectal cancer treatment continuum-applying current evidence to clinical practice
-
Peeters M, Price T. Biologic therapies in the metastatic colorectal cancer treatment continuum-applying current evidence to clinical practice. Cancer Treat Rev 2012;38:397-406.
-
(2012)
Cancer Treat Rev
, vol.38
, pp. 397-406
-
-
Peeters, M.1
Price, T.2
-
85
-
-
5444269445
-
Meta-analyses based on abstracted data: A step in the right direction, but only a first step
-
Piedbois P, Buyse M. Meta-analyses based on abstracted data: a step in the right direction, but only a first step. J Clin Oncol 2004;22:3839-41.
-
(2004)
J Clin Oncol
, vol.22
, pp. 3839-3841
-
-
Piedbois, P.1
Buyse, M.2
-
86
-
-
80755155711
-
Alternative end points to evaluate a therapeutic strategy in advanced colorectal cancer: Evaluation of progression-free survival, duration of disease control, and time to failure of strategy - An Aide et Recherche en Cancérologie Digestive Group Study
-
Chibaudel B, Bonnetain F, Shi Q, Buyse M, Tournigand C, Sargent DJ, et al. Alternative end points to evaluate a therapeutic strategy in advanced colorectal cancer: evaluation of progression-free survival, duration of disease control, and time to failure of strategy - an Aide et Recherche en Cancérologie Digestive Group Study. J Clin Oncol 2011;29:4199-204.
-
(2011)
J Clin Oncol
, vol.29
, pp. 4199-4204
-
-
Chibaudel, B.1
Bonnetain, F.2
Shi, Q.3
Buyse, M.4
Tournigand, C.5
Sargent, D.J.6
-
87
-
-
68949094312
-
Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy
-
Kopetz S, Chang GJ, Overman MJ, Eng C, Sargent DJ, Larson DW, et al. Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy. J Clin Oncol 2009;27:3677-83.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3677-3683
-
-
Kopetz, S.1
Chang, G.J.2
Overman, M.J.3
Eng, C.4
Sargent, D.J.5
Larson, D.W.6
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