Criteria for the validation of surrogate endpoints in randomized experiments

Biometrics

Volumn 54, Issue 3, 1998, Pages 1014-1029

  Buyse, Marc ^a,b   Molenberghs, Geert ^b  

^a INTERNATIONAL DRUG DEVELOPMENT INSTITUTE   (Belgium)

^b HASSELT UNIVERSITY   (Belgium)

Author keywords

Fieller's theorem; Perfect surrogate; Surrogate endpoint; Validation

Indexed keywords

REGRESSION ANALYSIS;

CONDITION; FIELLER'S THEOREM; INDICATOR VARIABLES; INDIVIDUAL LEVELS; LOWER CONFIDENCE LIMIT; PERFECT SURROGATE; POPULATION LEVELS; RANDOMIZED EXPERIMENTS; SURROGATE ENDPOINT; VALIDATION;

NORMAL DISTRIBUTION;

ARTICLE; DATA ANALYSIS; STATISTICAL ANALYSIS; STATISTICAL PARAMETERS; VALIDATION PROCESS;

EID: 0031708453     PISSN: 0006341X     EISSN: None     Source Type: Journal    
DOI: 10.2307/2533853     Document Type: Article

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