A Pictet-Spengler ligation for protein chemical modification

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 1, 2013, Pages 46-51

  Agarwal, Paresh ^a   Van Der Weijden, Joep ^a   Sletten, Ellen M ^a   Rabuka, David ^a   Bertozzi, Carolyn R ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Redwood Bioscience Inc   (United States)

Author keywords

Bioorthogonal chemistry; Protein conjugation; Reaction methodology

Indexed keywords

ALDEHYDE; GLYOXYLIC ACID; NUCLEOPHILE; TRASTUZUMAB; TRYPTAMINE;

ARTICLE; CHEMICAL BOND; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; PICTET SPENGLER REACTION; PRIORITY JOURNAL; PROTEIN MODIFICATION; SYNTHESIS;

ALDEHYDES; ANTIBODIES, MONOCLONAL, HUMANIZED; BIOENGINEERING; BIOLOGICAL THERAPY; KETONES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PROTEINS; TRYPTAMINES;

EID: 84871947711     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1213186110     Document Type: Article

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