메뉴 건너뛰기




Volumn 98, Issue 1, 2013, Pages 209-218

Effect of porosity on long-term degradation of poly (ε-caprolactone) scaffolds and their cellular response

Author keywords

Cell culture; Degradation; Poly ( caprolactone); Porosity; Scaffold

Indexed keywords

CAPROLACTONE; CELL INGROWTH; CELL PERFORMANCE; CELLULAR RESPONSE; COMPRESSIVE MODULI; DEGRADATION BEHAVIOR; DEGRADATION RATE; DEGRADATION STUDY; HIGH POROSITY; IN-VIVO; LOW POROSITY; MECHANICAL LOSS; PHOSPHATE BUFFER SOLUTIONS; PHYSICOCHEMICAL PROPERTY; STRUCTURAL COLLAPSE;

EID: 84871928117     PISSN: 01413910     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.polymdegradstab.2012.10.008     Document Type: Article
Times cited : (71)

References (39)
  • 1
    • 0034672872 scopus 로고    scopus 로고
    • Scaffolds in tissue engineering bone and cartilage
    • D.W. Hutmacher Scaffolds in tissue engineering bone and cartilage Biomaterials 21 2000 2529 2543
    • (2000) Biomaterials , vol.21 , pp. 2529-2543
    • Hutmacher, D.W.1
  • 2
    • 0033168271 scopus 로고    scopus 로고
    • In vitro degradation of a novel poly (lactide-co-glycolide) 75/25 foam
    • C.E. Holy, S.M. Dang, J.E. Davies, and M.S. Shoichet In vitro degradation of a novel poly (lactide-co-glycolide) 75/25 foam Biomaterials 20 1999 1177 1185
    • (1999) Biomaterials , vol.20 , pp. 1177-1185
    • Holy, C.E.1    Dang, S.M.2    Davies, J.E.3    Shoichet, M.S.4
  • 3
    • 64149117814 scopus 로고    scopus 로고
    • In vivo tissue response and degradation behavior of PLLA and stereocomplexed PLA nanofibers
    • D. Ishii, T.H. Ying, A. Mahara, S. Murakami, T. Yamaoka, and W.-k. Lee In vivo tissue response and degradation behavior of PLLA and stereocomplexed PLA nanofibers Biomacromolecules 10 2008 237 242
    • (2008) Biomacromolecules , vol.10 , pp. 237-242
    • Ishii, D.1    Ying, T.H.2    Mahara, A.3    Murakami, S.4    Yamaoka, T.5    Lee, W.-K.6
  • 4
    • 77956074627 scopus 로고    scopus 로고
    • Effect of micro-and macroporosity of bone tissue three-dimensional-poly (ε-Caprolactone) scaffold on human mesenchymal stem cells invasion, proliferation, and differentiation in Vitro
    • A. Salerno, D. Guarnieri, M. Iannone, S. Zeppetelli, and P. Netti Effect of micro-and macroporosity of bone tissue three-dimensional-poly (ε-Caprolactone) scaffold on human mesenchymal stem cells invasion, proliferation, and differentiation In Vitro Tissue Eng Part A 16 2010 2661 2673
    • (2010) Tissue Eng Part A , vol.16 , pp. 2661-2673
    • Salerno, A.1    Guarnieri, D.2    Iannone, M.3    Zeppetelli, S.4    Netti, P.5
  • 5
    • 64249125797 scopus 로고    scopus 로고
    • Engineered μ-bimodal poly (ε-caprolactone) porous scaffold for enhanced hMSC colonization and proliferation
    • A. Salerno, D. Guarnieri, M. Iannone, S. Zeppetelli, E. Di Maio, and S. Iannace Engineered μ-bimodal poly (ε-caprolactone) porous scaffold for enhanced hMSC colonization and proliferation Acta Biomater 5 2009 1082 1093
    • (2009) Acta Biomater , vol.5 , pp. 1082-1093
    • Salerno, A.1    Guarnieri, D.2    Iannone, M.3    Zeppetelli, S.4    Di Maio, E.5    Iannace, S.6
  • 6
    • 77957588918 scopus 로고    scopus 로고
    • The return of a forgotten polymer-Polycaprolactone in the 21st century
    • M.A. Woodruff, and D.W. Hutmacher The return of a forgotten polymer-Polycaprolactone in the 21st century Prog Polym Sci 35 2010 1217 1256
    • (2010) Prog Polym Sci , vol.35 , pp. 1217-1256
    • Woodruff, M.A.1    Hutmacher, D.W.2
  • 7
    • 35948986208 scopus 로고    scopus 로고
    • Biodegradable synthetic polymers for tissue engineering
    • P.A. Gunatillake, and R. Adhikari Biodegradable synthetic polymers for tissue engineering Eur Cell Mater 5 2003 1 16
    • (2003) Eur Cell Mater , vol.5 , pp. 1-16
    • Gunatillake, P.A.1    Adhikari, R.2
  • 8
    • 52649150222 scopus 로고    scopus 로고
    • Dynamics of in vitro polymer degradation of polycaprolactone-based scaffolds
    • C. Lam, M. Savalani, S. Teoh, and D. Hutmacher Dynamics of in vitro polymer degradation of polycaprolactone-based scaffolds Biomed Mater 3 2008 034108
    • (2008) Biomed Mater , vol.3 , pp. 034108
    • Lam, C.1    Savalani, M.2    Teoh, S.3    Hutmacher, D.4
  • 9
    • 55049126465 scopus 로고    scopus 로고
    • Customizing the degradation and load-bearing profile of 3D polycaprolactone-tricalcium phosphate scaffolds under enzymatic and hydrolytic conditions
    • A. Yeo, E. Sju, B. Rai, and S.H. Teoh Customizing the degradation and load-bearing profile of 3D polycaprolactone-tricalcium phosphate scaffolds under enzymatic and hydrolytic conditions J Biomed Mater Res B 87 2008 562 569
    • (2008) J Biomed Mater Res B , vol.87 , pp. 562-569
    • Yeo, A.1    Sju, E.2    Rai, B.3    Teoh, S.H.4
  • 11
    • 0026646773 scopus 로고
    • In vivo degradation of massive poly(α-hydroxy acids): Validation of in vitro findings
    • M. Therin, P. Christel, S. Li, H. Garreau, and M. Vert In vivo degradation of massive poly(α-hydroxy acids): validation of In vitro findings Biomaterials 13 1992 594 600
    • (1992) Biomaterials , vol.13 , pp. 594-600
    • Therin, M.1    Christel, P.2    Li, S.3    Garreau, H.4    Vert, M.5
  • 12
    • 0034124199 scopus 로고    scopus 로고
    • In vitro and in vivo degradation of porous poly(dl-lactic-co-glycolic acid) foams
    • L. Lu, S.J. Peter, M.D. Lyman, H.-L. Lai, S.M. Leite, and J.A. Tamada In vitro and in vivo degradation of porous poly(dl-lactic-co-glycolic acid) foams Biomaterials 21 2000 1837 1845
    • (2000) Biomaterials , vol.21 , pp. 1837-1845
    • Lu, L.1    Peter, S.J.2    Lyman, M.D.3    Lai, H.-L.4    Leite, S.M.5    Tamada, J.A.6
  • 13
    • 28744438866 scopus 로고    scopus 로고
    • The in vivo degradation, absorption and excretion of PCL-based implant
    • H. Sun, L. Mei, C. Song, X. Cui, and P. Wang The in vivo degradation, absorption and excretion of PCL-based implant Biomaterials 27 2006 1735 1740
    • (2006) Biomaterials , vol.27 , pp. 1735-1740
    • Sun, H.1    Mei, L.2    Song, C.3    Cui, X.4    Wang, P.5
  • 14
    • 78649451373 scopus 로고    scopus 로고
    • Physicochemical characterisation of degrading polycaprolactone scaffolds
    • L.A. Bosworth, and S. Downes Physicochemical characterisation of degrading polycaprolactone scaffolds Polym Degrad Stab 95 2010 2269 2276
    • (2010) Polym Degrad Stab , vol.95 , pp. 2269-2276
    • Bosworth, L.A.1    Downes, S.2
  • 16
    • 72649106069 scopus 로고    scopus 로고
    • The influence of hydroxyapatite particles on in vitro degradation behavior of poly ε-caprolactone-based composite scaffolds
    • V. Guarino, P. Taddei, M.D. Foggia, C. Fagnano, G. Ciapetti, and L. Ambrosio The influence of hydroxyapatite particles on in vitro degradation behavior of poly ε-caprolactone-based composite scaffolds Tissue Eng Part A 15 2009 3655 3668
    • (2009) Tissue Eng Part A , vol.15 , pp. 3655-3668
    • Guarino, V.1    Taddei, P.2    Foggia, M.D.3    Fagnano, C.4    Ciapetti, G.5    Ambrosio, L.6
  • 17
    • 36949038531 scopus 로고    scopus 로고
    • The degradation profile of novel, bioresorbable PCL-TCP scaffolds: An in vitro and in vivo study
    • A. Yeo, B. Rai, E. Sju, J. Cheong, and S. Teoh The degradation profile of novel, bioresorbable PCL-TCP scaffolds: an in vitro and in vivo study J Biomed Mater Res A 84 2008 208 218
    • (2008) J Biomed Mater Res A , vol.84 , pp. 208-218
    • Yeo, A.1    Rai, B.2    Sju, E.3    Cheong, J.4    Teoh, S.5
  • 19
    • 70249118953 scopus 로고    scopus 로고
    • Knowledge-based approach towards hydrolytic degradation of polymer-based biomaterials
    • D. Hofmann, M. Entrialgo-Casta o, K. Kratz, and A. Lendlein Knowledge-based approach towards hydrolytic degradation of polymer-based biomaterials Adv Funct Mater 21 2009 3237 3245
    • (2009) Adv Funct Mater , vol.21 , pp. 3237-3245
    • Hofmann, D.1    Entrialgo-Casta, O.M.2    Kratz, K.3    Lendlein, A.4
  • 20
    • 79960252886 scopus 로고    scopus 로고
    • Fine tuning micellar core-forming block of poly(ethylene glycol)-block-poly(ε-caprolactone) amphiphilic copolymers based on chemical modification for the solubilization and delivery of doxorubicin
    • J. Yan, Z. Ye, M. Chen, Z. Liu, Y. Xiao, and Y. Zhang Fine tuning micellar core-forming block of poly(ethylene glycol)-block-poly(ε- caprolactone) amphiphilic copolymers based on chemical modification for the solubilization and delivery of doxorubicin Biomacromolecules 12 2011 2562 2572
    • (2011) Biomacromolecules , vol.12 , pp. 2562-2572
    • Yan, J.1    Ye, Z.2    Chen, M.3    Liu, Z.4    Xiao, Y.5    Zhang, Y.6
  • 21
    • 24644486326 scopus 로고    scopus 로고
    • Fabrication of three-dimensional porous scaffolds of complicated shape for tissue engineering. I. Compression molding based on flexible-rigid combined mold
    • L. Wu, H. Zhang, J. Zhang, and J. Ding Fabrication of three-dimensional porous scaffolds of complicated shape for tissue engineering. I. Compression molding based on flexible-rigid combined mold Tissue Eng 11 2005 1105 1114
    • (2005) Tissue Eng , vol.11 , pp. 1105-1114
    • Wu, L.1    Zhang, H.2    Zhang, J.3    Ding, J.4
  • 22
    • 56249106568 scopus 로고    scopus 로고
    • Synthesis, characterization and degradability of the novel aliphatic polyester bearing pendant N-isopropylamide functional groups
    • W. Dai, H. Huang, Z. Du, and M. Lang Synthesis, characterization and degradability of the novel aliphatic polyester bearing pendant N-isopropylamide functional groups Polym Degrad Stab 93 2008 2089 2095
    • (2008) Polym Degrad Stab , vol.93 , pp. 2089-2095
    • Dai, W.1    Huang, H.2    Du, Z.3    Lang, M.4
  • 23
    • 67649884738 scopus 로고    scopus 로고
    • Phase separation, pore structure, and properties of nanofibrous gelatin scaffolds
    • X. Liu, and P. Ma Phase separation, pore structure, and properties of nanofibrous gelatin scaffolds Biomaterials 30 2009 4094 4103
    • (2009) Biomaterials , vol.30 , pp. 4094-4103
    • Liu, X.1    Ma, P.2
  • 24
    • 0001818465 scopus 로고    scopus 로고
    • A novel fabrication method of macroporous biodegradable polymer scaffolds using gas foaming salt as a porogen additive
    • Y. Nam, J. Yoon, and T. Park A novel fabrication method of macroporous biodegradable polymer scaffolds using gas foaming salt as a porogen additive J Biomed Mater Res 53 2000 1 7
    • (2000) J Biomed Mater Res , vol.53 , pp. 1-7
    • Nam, Y.1    Yoon, J.2    Park, T.3
  • 25
    • 1642389170 scopus 로고    scopus 로고
    • Novel approach to fabricate keratin sponge scaffolds with controlled pore size and porosity
    • K. Katoh, T. Tanabe, and K. Yamauchi Novel approach to fabricate keratin sponge scaffolds with controlled pore size and porosity Biomaterials 25 2004 4255 4262
    • (2004) Biomaterials , vol.25 , pp. 4255-4262
    • Katoh, K.1    Tanabe, T.2    Yamauchi, K.3
  • 26
    • 44549083088 scopus 로고    scopus 로고
    • Dynamic mechanical behavior of starch-based scaffolds in dry and physiologically simulated conditions: Effect of porosity and pore size
    • S. Ghosh, V. Gutierrez, C. Fernandez, M. Rodriguez-Perez, J. Viana, and R. Reis Dynamic mechanical behavior of starch-based scaffolds in dry and physiologically simulated conditions: effect of porosity and pore size Acta Biomater 4 2008 950 959
    • (2008) Acta Biomater , vol.4 , pp. 950-959
    • Ghosh, S.1    Gutierrez, V.2    Fernandez, C.3    Rodriguez-Perez, M.4    Viana, J.5    Reis, R.6
  • 27
  • 28
    • 1842739438 scopus 로고    scopus 로고
    • A novel pH-sensitive hydrogel composed of N, O-carboxymethyl chitosan and alginate cross-linked by genipin for protein drug delivery
    • S. Chen, Y. Wu, F. Mi, Y. Lin, L. Yu, and H. Sung A novel pH-sensitive hydrogel composed of N, O-carboxymethyl chitosan and alginate cross-linked by genipin for protein drug delivery J Control Release 96 2004 285 300
    • (2004) J Control Release , vol.96 , pp. 285-300
    • Chen, S.1    Wu, Y.2    Mi, F.3    Lin, Y.4    Yu, L.5    Sung, H.6
  • 29
    • 77349121845 scopus 로고    scopus 로고
    • Effect of porogen on the physico-chemical properties and degradation performance of PLGA scaffolds
    • R. Dorati, C. Colonna, I. Genta, T. Modena, and B. Conti Effect of porogen on the physico-chemical properties and degradation performance of PLGA scaffolds Polym Degrad Stab 95 2010 694 701
    • (2010) Polym Degrad Stab , vol.95 , pp. 694-701
    • Dorati, R.1    Colonna, C.2    Genta, I.3    Modena, T.4    Conti, B.5
  • 30
    • 0031554171 scopus 로고    scopus 로고
    • Polymer bulk erosion
    • A. G pferich Polymer bulk erosion Macromolecules 30 1997 2598 2604
    • (1997) Macromolecules , vol.30 , pp. 2598-2604
    • Pferich, A.G.1
  • 31
    • 79251568316 scopus 로고    scopus 로고
    • Mathematical modeling of degradation for biodegradable bulk-erosive polymers: Size-dependence in tissue engineering scaffold and drug delivery system
    • Y. Chen, S. Zhou, and Q. Li Mathematical modeling of degradation for biodegradable bulk-erosive polymers: size-dependence in tissue engineering scaffold and drug delivery system Acta Biomater 7 2011 1140 1149
    • (2011) Acta Biomater , vol.7 , pp. 1140-1149
    • Chen, Y.1    Zhou, S.2    Li, Q.3
  • 32
    • 9244265526 scopus 로고    scopus 로고
    • Synthesis and degradation of PLA-PCL-PLA triblock copolymer prepared by successive polymerization of ε-caprolactone and dl-lactide
    • M. Huang, S. Li, and M. Vert Synthesis and degradation of PLA-PCL-PLA triblock copolymer prepared by successive polymerization of ε-caprolactone and dl-lactide Polymer 45 2004 8675 8681
    • (2004) Polymer , vol.45 , pp. 8675-8681
    • Huang, M.1    Li, S.2    Vert, M.3
  • 33
    • 61349170097 scopus 로고    scopus 로고
    • Degradation of synthetic polymeric scaffolds for bone and cartilage tissue repairs
    • D. Eglin, D. Mortisen, and M. Alini Degradation of synthetic polymeric scaffolds for bone and cartilage tissue repairs Soft Matter 5 2009 938 947
    • (2009) Soft Matter , vol.5 , pp. 938-947
    • Eglin, D.1    Mortisen, D.2    Alini, M.3
  • 34
    • 41149151684 scopus 로고    scopus 로고
    • In vitro and in vivo degradation of poly(L-lactide-co-glycolide) films and scaffolds
    • E. Pamula, and E. Menaszek In vitro and in vivo degradation of poly(L-lactide-co-glycolide) films and scaffolds J Mater Sci - Mater Med 19 2008 2063 2070
    • (2008) J Mater Sci - Mater Med , vol.19 , pp. 2063-2070
    • Pamula, E.1    Menaszek, E.2
  • 35
    • 73549109410 scopus 로고    scopus 로고
    • Surface modification of PCL-TCP scaffolds improve interfacial mechanical interlock and enhance early bone formation: An in vitro and in vivo characterization
    • A. Yeo, W. Wong, H. Khoo, and S. Teoh Surface modification of PCL-TCP scaffolds improve interfacial mechanical interlock and enhance early bone formation: an in vitro and in vivo characterization J Biomed Mater Res A 92 2010 311 321
    • (2010) J Biomed Mater Res A , vol.92 , pp. 311-321
    • Yeo, A.1    Wong, W.2    Khoo, H.3    Teoh, S.4
  • 36
    • 28844449612 scopus 로고    scopus 로고
    • Effects of porosity and pore size on in vitro degradation of three-dimensional porous poly (D, L-lactide-co-glycolide) scaffolds for tissue engineering
    • L. Wu, and J. Ding Effects of porosity and pore size on in vitro degradation of three-dimensional porous poly (D, L-lactide-co-glycolide) scaffolds for tissue engineering J Biomed Mater Res A 75 2005 767 777
    • (2005) J Biomed Mater Res A , vol.75 , pp. 767-777
    • Wu, L.1    Ding, J.2
  • 37
    • 0031893301 scopus 로고    scopus 로고
    • The effects of porosity on in vitro degradation of polylactic acid-polyglycolic acid implants used in repair of articular cartilage
    • K. Athanasiou, J. Schmitz, and C. Agrawal The effects of porosity on in vitro degradation of polylactic acid-polyglycolic acid implants used in repair of articular cartilage Tissue Eng 4 1998 53 63
    • (1998) Tissue Eng , vol.4 , pp. 53-63
    • Athanasiou, K.1    Schmitz, J.2    Agrawal, C.3
  • 38
    • 3242707718 scopus 로고    scopus 로고
    • The effect of pore size on cell adhesion in collagen-GAG scaffolds
    • F.J. O'Brien, B.A. Harley, I.V. Yannas, and L.J. Gibson The effect of pore size on cell adhesion in collagen-GAG scaffolds Biomaterials 26 2005 433 441
    • (2005) Biomaterials , vol.26 , pp. 433-441
    • O'Brien, F.J.1    Harley, B.A.2    Yannas, I.V.3    Gibson, L.J.4
  • 39
    • 57349123316 scopus 로고    scopus 로고
    • Method to analyze three-dimensional cell distribution and infiltration in degradable scaffolds
    • P. Thevenot, A. Nair, J. Dey, J. Yang, and L. Tang Method to analyze three-dimensional cell distribution and infiltration in degradable scaffolds Tissue Eng Part C Meth 14 2008 319
    • (2008) Tissue Eng Part C Meth , vol.14 , pp. 319
    • Thevenot, P.1    Nair, A.2    Dey, J.3    Yang, J.4    Tang, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.