Effect of developmental dioxin exposure on methylation and expression of specific imprinted genes in mice

Reproductive Toxicology

Volumn 35, Issue 1, 2013, Pages 150-155

  Somm, Emmanuel ^a   Stouder, Christelle ^a   Paoloni Giacobino, Ariane ^a  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

Dioxin; Endocrine disruptors; Epigenetic; Expression; Imprinting; Methylation

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; INSULIN GROWTH FACTOR 2 RECEPTOR; MESSENGER RNA; SOMATOMEDIN RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; FEMALE; GENE; GENE ACTIVITY; GENE EXPRESSION; GENE FUNCTION; IGF2R GENE; LIVER; MALE; MOUSE; NONHUMAN; PEG3 GENE; PROGENY; SEMEN ANALYSIS; SKELETAL MUSCLE; SNRPN GENE; SPERMATOZOON COUNT; TOXICITY TESTING;

ANIMALS; DNA METHYLATION; ENDOCRINE DISRUPTORS; FEMALE; GENOMIC IMPRINTING; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LIVER; MALE; MATERNAL-FETAL EXCHANGE; MICE; MUSCLE, SKELETAL; PREGNANCY; RECEPTOR, IGF TYPE 2; RNA, MESSENGER; SNRNP CORE PROTEINS; SPERM COUNT; TETRACHLORODIBENZODIOXIN;

MUS;

EID: 84871925490     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2012.10.011     Document Type: Article

References (34)

1. Ahmed R.G., Perinatal T.C.D.D. exposure alters developmental neuroendocrine system. Food and Chemical Toxicology 2011, 49:1276-1284.
2. Eskenazi B., Kimmel G. Workshop on perinatal exposure to dioxin-like compounds. II. Reproductive effects. Environmental Health Perspectives 1995, 103(Suppl. 2):143-145.
3. Le T.N., Johansson A. Impact of chemical warfare with agent orange on women's reproductive lives in Vietnam: a pilot study. Reproductive Health Matters 2001, 9:156-164.
4. Mocarelli P., Gerthoux P.M., Ferrari E., Patterson D.G.J., Kieszak S.M., Brambilla P., et al. Paternal concentrations of dioxin and sex ratio of offspring. Lancet 2000, 355:1858-1863.
5. Ishihara K., Ohsako S., Tasaka K., Harayama H., Miyake M., Warita K., et al. When does the sex ratio of offspring of the paternal 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure decrease: in the spermatozoa stage or at fertilization. Reproductive Toxicology 2010, 29:68-73.
6. Ishihara K., Warita K., Tanida T., Sugawara T., Kitagawa H., Hoshi N. Does paternal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) affect the sex ratio of offspring. Journal of Veterinary Medical Science 2007, 69:347-352.
7. Foster W.G., Maharaj-Briceño S., Cyr D.G. Dioxin-induced changes in epididymal sperm count and spermatogenesis. Environmental Health Perspectives 2010, 118:458-464.
8. Bell D.R., Clode S., Fan M.Q., Fernandes A., Foster P.M., Jiang T., et al. Interpretation of studies on the developmental reproductive toxicology of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male offspring. Food and Chemical Toxicology 2010, 48:1439-1447.
9. Ikeda M., Tamura M., Yamashita J., Suzuki C., Tomita T. Repeated in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure affects male gonads in offspring, leading to sex ratio changes in F2 progeny. Toxicology and Applied Pharmacology 2005, 206:351-355.
10. Li B., Liu H.Y., Dai L.J., Lu J.C., Yang Z.M., Huang L. The early embryo loss caused by 2,3,7,8-tetrachlorodibenzo-p-dioxin may be related to the accumulation of this compound in the uterus. Reproductive Toxicology 2006, 21:301-306.
11. Nayyar T., Bruner-Tran K.L., Piestrzeniewicz-Ulanska D., Osteen K.G. Developmental exposure of mice to TCDD elicits a similar uterine phenotype in adult animals as observed in women with endometriosis. Reproductive Toxicology 2007, 23:326-336.
12. Bruner-Tran K.L., Osteen K.G. Developmental exposure to TCDD reduces fertility and negatively affects pregnancy outcomes across multiple generations. Reproductive Toxicology 2011, 31:344-350.
13. Wu Q., Ohsako S., Ishimura R., Suzuki J.S., Tohyama C. Exposure of mouse preimplantation embryos to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) alters the methylation status of imprinted genes H19 and Igf2. Biology of Reproduction 2004, 70:1790-1797.
14. Wutz A., Smrzka O.W., Schweifer N., Schellander K., Wagner E.F., Barlow D.P. Imprinted expression of the Igf2r gene depends on an intronic CpG island. Nature 1997, 389:745-749.
15. Sleutels F., Zwart R., Barlow D.P. The non-coding Air RNA is required for silencing autosomal imprinted genes. Nature 2002, 415:810-813.
16. Reinhart B., Paoloni-Giacobino A., Chaillet J.R. Specific differentially methylated domain sequences direct the maintenance of methylation at imprinted genes. Molecular and Cellular Biology 2006, 26:8347-8356.
17. Chaillet J.R., Bader D.S., Leder P. Regulation of genomic imprinting by gametic and embryonic processes. Genes and Development 1995, 9:1177-1187.
18. Stouder C., Paoloni-Giacobino A. Specific transgenerational imprinting effects of the endocrine disruptor methoxychlor on male gametes. Reproduction 2011, 141:207-216.
19. Manikkam M., Guerrero-Bosagna C., Tracey R., Haque M.M., Skinner M.K. Transgenerational actions of environmental compounds on reproductive disease and identification of epigenetic biomarkers of ancestral exposures. PLoS ONE 2012, 7:e31901.
20. La Merrill M., Harper R., Birnbaum L.S., Cardiff R.D., Threadgill D.W. Maternal dioxin exposure combined with a diet high in fat increases mammary cancer incidence in mice. Environmental Health Perspectives 2010, 118:596-601.
21. Seidl C.I., Stricker S.H., Barlow D.P. The imprinted Air ncRNA is an atypical RNAPII transcript that evades splicing and escapes nuclear export. EMBO Journal 2006, 25:3565-3575.
22. Rasoulpour R.J., LeBaron M.J., Ellis-Hutchings R.G., Klapacz J., Gollapudi B.B. Epigenetic screening in product safety assessment: are we there yet?. Toxicology Mechanisms and Methods 2011, 21:298-311.
23. Vaissière T., Sawan C., Herceg Z. Epigenetic interplay between histone modifications and DNA methylation in gene silencing. Mutation Research 2008, 659:40-48.
24. Chuang J.C., Jones P.A. Epigenetics and microRNAs. Pediatric Research 2007, 61. 24R-9R.
25. Latchoumycandane C., Chitra C., Mathur P. Induction of oxidative stress in rat epididymal sperm after exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Archives of Toxicology 2002, 76:113-118.
26. McConaha M.E., Ding T., Lucas J.A., Arosh J.A., Osteen K.G., Bruner-Tran K.L. Preconception omega-3 fatty acid supplementation of adult male mice with a history of developmental 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure prevents preterm birth in unexposed female partners. Reproduction 2011, 142:235-241.
27. Schneider E., Pliushch G., El Hajj N., Galetzka D., Puhl A., Schorsch M., et al. Spatial, temporal and interindividual epigenetic variation of functionally important DNA methylation patterns. Nucleic Acids Research 2010, 38:3880-3890.
28. Gosden R., Trasler J., Lucifero D., Faddy M. Rare congenital disorders, imprinted genes, and assisted reproductive technology. Lancet 2003, 361:1975-1977.
29. Coan P.M., Burton G.J., Ferguson-Smith A.C. Imprinted genes in the placenta-a review. Placenta 2005, 26(Suppl. A):S10-S20.
30. Liu Y., Zhou C., Xu Y., Fang C., Zhang M. Pregnancy outcome in preimplantation genetic diagnosis cycle by blastomere biopsy is related to both quality and quantity of embryos on day 3. Fertility and Sterility 2009, 91:1355-1357.
31. Pliushch G., Schneider E., Weise D., El Hajj N., Tresch A., Seidmann L., et al. Extreme methylation values of imprinted genes in human abortions and stillbirths. American Journal of Pathology 2010, 176:1084-1090.
32. Ludwig T., Eggenschwiler J., Fisher P., D'Ercole A.J., Davenport M.L., Efstratiadis A. Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds. Developmental Biology 1996, 177:517-535.
33. Hamatani T. Human spermatozoal RNAs. Fertility and Sterility 2012, 97:275-281.
34. Reik W., Constância M., Fowden A., Anderson N., Dean W., Ferguson-Smith A., et al. Regulation of supply and demand for maternal nutrients in mammals by imprinted genes. Journal of Physiology 2003, 547:35-44.