Extreme methylation values of imprinted genes in human abortions and stillbirths

American Journal of Pathology

Volumn 176, Issue 3, 2010, Pages 1084-1090

  Pliushch, Galyna ^a   Schneider, Eberhard ^a   Weise, Daniela ^a   El Hajj, Nady ^a   Tresch, Achim ^b   Seidmann, Larissa ^a   Coerdt, Wiltrud ^a   Müller, Annette M ^c   Zechner, Ulrich ^a   Haaf, Thomas ^d  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY HOSPITAL BONN   (Germany)

^d UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BISULFITE;

ABORTION; ALLELE; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; FERTILIZATION; FETUS; GENE; GENOME IMPRINTING; H19 GENE; HUMAN; HUMAN TISSUE; LIT1 GENE; MEG3 GENE; NESP55 GENE; PEG3 GENE; PRIORITY JOURNAL; PYROSEQUENCING; SNRPN GENE; SPONTANEOUS ABORTION; STILLBIRTH;

EID: 77749279482     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2010.090764     Document Type: Article

References (37)

1. Brown S: Miscarriage and its associations. Semin Reprod Med 2008, 26:391-400
2. Warren JE, Silver RM: Genetics of pregnancy loss. Clin Obstet Gynecol 2008, 51:84-95
3. Boue A, Boue J, Gropp A: Cytogenetics of pregnancy wastage. Adv Hum Genet 1985, 14:1-57
4. Eiben B, Bartels I, Bähr-Porsch S, Borgmann S, Gatz G, Gellert G, Goebel R, Hammans W, Hentemann M, Osmers R, Rauskolb R, Hansmann I: Cytogenetic analysis of 750 spontaneous abortions with the direct-preparation method of chorionic villi and its implications for studying genetic causes of pregnancy wastage. Am J Hum Genet 1990, 47:656-663
5. Jaenisch R, Bird A: Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 2003, 33:245-254
6. Vaissière T, Sawan C, Herceg Z: Epigenetic interplay between histone modifications and DNA methylation in gene silencing. Mutat Res 2008, 659:40-48
7. Bartolomei MS, Tilghman SM: Genomic imprinting in mammals. Annu Rev Genet 1997, 31:493-525
8. Ferguson-Smith AC, Surani MA: Imprinting and the epigenetic asymmetry between parental genomes. Science 2001, 293:1086-1089
9. Hajkova P, Erhardt S, Lane N, Haaf T, El-Maarri O, Reik W, Walter J, Surani MA: Epigenetic reprogramming in mouse primordial germ cells. Mech Dev 2002, 117:15-23
10. Mayer W, Niveleau A, Walter J, Fundele R, Haaf T: Demethylation of the zygotic paternal genome. Nature 2000, 403:501-502
11. Reik W, Dean W, Walter J: Epigenetic reprogramming in mammalian development. Science 2001, 293:1089-1093
12. Miozzo M, Simoni G: The role of imprinted genes in fetal growth. Biol Neonate 2002, 81:217-228
13. Constância M, Kelsey G, Reik W: Resourceful imprinting. Nature 2004, 432:53-57
14. Shi W, Haaf T: Aberrant methylation patterns at the two-cell stage as an indicator of early developmental failure. Mol Reprod Dev 2002, 63:329-334
15. Khosla S, Dean W, Brown D, Reik W, Feil R: Culture of preimplantation mouse embryos affects fetal development and the expression of imprinted genes. Biol Reprod 2001, 64:918-926
16. Young LE, Fernandes K, McEvoy TG, Butterwith SC, Gutierrez CG, Carolan C, Broadbent PJ, Robinson JJ, Wilmut I, Sinclair KD: Epigenetic change in IGF2R is associated with fetal overgrowth after sheep embryo culture. Nat Genet 2001, 27:153-154
17. Bennett-Baker PE, Wilkowski J, Burke DT: Age-associated activation of epigenetically repressed genes in the mouse. Genetics 2003, 165:2055-2062
18. Goyal R, Reinhardt R, Jeltsch A: Accuracy of DNA methylation pattern preservation by the Dnmt1 methyltransferase. Nucleic Acids Res 2006, 34:1182-1188
19. Horsthemke B: Epimutation in human disease. Curr Top Microbiol Immunol 2006, 310:45-59
20. Sutherland JE, Costa M: Epigenetics and the environment. Ann NY Acad Sci 2003, 983:151-160
21. Temple IK: Imprinting in human disease with special reference to transient neonatal diabetes and Beckwith-Wiedemann syndrome. Endocr Dev 2007, 12:113-123
22. Feinberg AP: Phenotypic plasticity and the epigenetics of human disease. Nature 2007, 447:433-440
23. Hatchwell E, Greally JM: The potential role of epigenomic dysregulation in complex human disease. Trends Genet 2007, 23:588-595
24. Foley DL, Craig JM, Morley R, Olsson CA, Dwyer T, Smith K, Saffery R: Prospects for epigenetic epidemiology. Am J Epidemiol 2009, 169:389-400
25. Ruf N, Dunzinger U, Brinckmann A, Haaf T, Nürnberg P, Zechner U: Expression profiling of uniparental mouse embryos is inefficient in identifying novel imprinted genes. Genomics 2006, 87:509-519
26. Pfaffl MW, Horgan GW, Dempfle L: Relative Expression Software Tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res 2002, 30:E36
27. Sasaki H, Ishihara K, Kato R: Mechanisms of Igf2/H19 imprinting: DNA methylation, chromatin and long-distance gene regulation. J Biochem 2000, 127:711-715
28. Astuti D, Latif F, Wagner K, Gentle D, Cooper WN, Catchpoole D, Grundy R, Ferguson-Smith AC, Maher ER: Epigenetic alteration at the DLK1-GTL2 imprinted domain in human neoplasia: analysis of neuroblastoma, phaeochromocytoma and Wilms' tumour. Br J Cancer 2005, 92:1574-1580
29. Moore T, Haig D: Genomic imprinting in mammalian development: a parental tug-of-war. Trends Genet 1991, 7:45-49
30. Jelinic P, Shaw P: Loss of imprinting and cancer. J Path 2007, 211:261-268
31. Cui H, Horon IL, Ohlsson R, Hamilton SR, Feinberg AP: Loss of imprinting in normal tissue of colorectal cancer patients with microsatellite instability. Nat Med 1998, 4:1276-1280
32. Sakatani T, Wei M, Katoh M, Okita C, Wada D, Mitsuya K, Meguro M, Ikeguchi M, Ito H, Tycko B, Oshimura M: Epigenetic heterogeneity at imprinted loci in normal populations. Biochem Biophys Res Commun 2001, 283:1124-1130
33. Kraemer S: The fragile male. BMJ 2000, 321:1609-1612
34. Mizuno R: The male/female ratio of fetal deaths and births in Japan. Lancet 2000, 356:738-739
35. Hansen D, Moller H, Olsen J: Severe periconceptional life events and the sex ratio in offspring: follow up study based on five national registers. BMJ 1999, 319:548-549
36. Lewis A, Mitsuya K, Umlauf D, Smith P, Dean W, Walter J, Higgins M, Feil R, Reik W: Imprinting on distal chromosome 7 in the placenta involves repressive histone methylation independent of DNA methylation. Nat Genet 2004, 36:1291-1295
37. Fortier AL, Lopes FL, Darricarrè re N, Martel J, Trasler JM: Superovulation alters the expression of imprinted genes in the midgestation mouse placenta. Hum Mol Genet 2008, 17:1653-1665