Postoperative subcutaneous instillation of low-dose ketorolac but not hydromorphone reduces wound exudate concentrations of interleukin-6 and interleukin-10 and improves analgesia following cesarean delivery

Journal of Pain

Volumn 14, Issue 1, 2013, Pages 48-56

  Carvalho, Brendan ^a   Lemmens, Harry J ^a   Ting, Vicki ^b   Angst, Martin S ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Department of Anesthesia   (United States)

Author keywords

analgesia; bupivacaine; Cesarean; hydromorphone; interleukin 10; interleukin 6; ketorolac; wound

Indexed keywords

BUPIVACAINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYDROMORPHONE; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; INTERLEUKIN 8; KETOROLAC; TUMOR NECROSIS FACTOR;

ADULT; ANALGESIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CESAREAN SECTION; CONTINUOUS INFUSION; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG INSTILLATION; FEMALE; HUMAN; INFLAMMATION; LOW DRUG DOSE; MAJOR CLINICAL STUDY; POSTOPERATIVE ANALGESIA; POSTOPERATIVE PAIN; RANDOMIZED CONTROLLED TRIAL; SURGICAL WOUND; UNSPECIFIED SIDE EFFECT; WOUND FLUID; WOUND HEALING IMPAIRMENT; WOUND INFECTION;

ADULT; ANALGESICS, OPIOID; ANESTHETICS, LOCAL; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BUPIVACAINE; CESAREAN SECTION; CYTOKINES; DOUBLE-BLIND METHOD; EXUDATES AND TRANSUDATES; FEMALE; HUMANS; HYDROMORPHONE; INJECTIONS, SUBCUTANEOUS; INTERLEUKIN-10; INTERLEUKIN-6; KETOROLAC; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; POSTOPERATIVE CARE; PREGNANCY;

EID: 84871924255     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2012.10.002     Document Type: Article

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