-
1
-
-
65949087007
-
High affinity interaction of the p53 peptide-analogue with human Mdm2 and Mdmx
-
Czarna A, Popowicz GM, Pecak A, Wolf S, Dubin G, Holak TA (2009) High affinity interaction of the p53 peptide-analogue with human Mdm2 and Mdmx. Cell Cycle 8:1176-1184
-
(2009)
Cell Cycle
, vol.8
, pp. 1176-1184
-
-
Czarna, A.1
Popowicz, G.M.2
Pecak, A.3
Wolf, S.4
Dubin, G.5
Holak, T.A.6
-
2
-
-
63849271797
-
Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX
-
Pazgier M, Liu M, Zou G, Yuan W, Li C, Li J, Monbo J, Zella D, Tarasov SG, Lu W (2009) Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX. Proc Natl Acad Sci USA 106:4665-4670
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 4665-4670
-
-
Pazgier, M.1
Liu, M.2
Zou, G.3
Yuan, W.4
Li, C.5
Li, J.6
Monbo, J.7
Zella, D.8
Tarasov, S.G.9
Lu, W.10
-
3
-
-
76249126943
-
Structure-based design of high affinity peptides inhibiting the interaction of p53 with MDM2 and MDMX
-
Phan J, Li Z, Kasprzak A, Li B, Sebti S, Guida W, Schonbrunn E, Chen J (2010) Structure-based design of high affinity peptides inhibiting the interaction of p53 with MDM2 and MDMX. J Biol Chem 285:2174-2183
-
(2010)
J Biol Chem
, vol.285
, pp. 2174-2183
-
-
Phan, J.1
Li, Z.2
Kasprzak, A.3
Li, B.4
Sebti, S.5
Guida, W.6
Schonbrunn, E.7
Chen, J.8
-
4
-
-
22944473048
-
Structure-based design of potent non-peptide MDM2 inhibitors
-
Ding K, Lu Y, Nikolovska-Coleska Z, Qiu S, Ding Y, Gao W, Stuckey J, Krajewski K, Roller PP, Tomita Y, Parrish DA, Deschamps JR, Wang S (2005) Structure-based design of potent non-peptide MDM2 inhibitors. J Am Chem Soc 127:10130-10131
-
(2005)
J Am Chem Soc
, vol.127
, pp. 10130-10131
-
-
Ding, K.1
Lu, Y.2
Nikolovska-Coleska, Z.3
Qiu, S.4
Ding, Y.5
Gao, W.6
Stuckey, J.7
Krajewski, K.8
Roller, P.P.9
Tomita, Y.10
Parrish, D.A.11
Deschamps, J.R.12
Wang, S.13
-
5
-
-
41649102468
-
Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition
-
Shangary S, Qin D, McEachern D, Liu M, Miller RS, Qiu S, Nikolovska-Coleska Z, Ding K, Wang G, Chen J, Bernard D, Zhang J, Lu Y, Gu Q, Shah RB, Pienta KJ, Ling X, Kang S, Guo M, Sun Y, Yang D, Wang S (2008) Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition. Proc Natl Acad Sci USA 105:3933-3938
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 3933-3938
-
-
Shangary, S.1
Qin, D.2
McEachern, D.3
Liu, M.4
Miller, R.S.5
Qiu, S.6
Nikolovska-Coleska, Z.7
Ding, K.8
Wang, G.9
Chen, J.10
Bernard, D.11
Zhang, J.12
Lu, Y.13
Gu, Q.14
Shah, R.B.15
Pienta, K.J.16
Ling, X.17
Kang, S.18
Guo, M.19
Sun, Y.20
Yang, D.21
Wang, S.22
more..
-
6
-
-
77951224332
-
Identification and characterization of thefirst small molecule inhibitor of MDMX
-
Reed D, Shen Y, Shelat AA, Arnold LA, Ferreira AM, Zhu F, Mills N, Smithson DC, Regni CA, Bashford D, Cicero SA, Schulman BA, Jochemsen AG, Guy RK, Dyer MA (2010) Identification and characterization of thefirst small molecule inhibitor of MDMX. J Biol Chem 285:10786-10796
-
(2010)
J Biol Chem
, vol.285
, pp. 10786-10796
-
-
Reed, D.1
Shen, Y.2
Shelat, A.A.3
Arnold, L.A.4
Ferreira, A.M.5
Zhu, F.6
Mills, N.7
Smithson, D.C.8
Regni, C.A.9
Bashford, D.10
Cicero, S.A.11
Schulman, B.A.12
Jochemsen, A.G.13
Guy, R.K.14
Dyer, M.A.15
-
7
-
-
79851497821
-
Novel pyrrolopyrimi-dine-based alpha-helix mimetics: Cell-permeable inhibitors of protein-protein interactions
-
Lee JH, Zhang Q, Jo S, Chai SC, Oh M, Im W, Lu H, Lim HS (2011) Novel pyrrolopyrimi-dine-based alpha-helix mimetics: cell-permeable inhibitors of protein-protein interactions. J Am Chem Soc 133:676-679
-
(2011)
J Am Chem Soc
, vol.133
, pp. 676-679
-
-
Lee, J.H.1
Zhang, Q.2
Jo, S.3
Chai, S.C.4
Oh, M.5
Im, W.6
Lu, H.7
Lim, H.S.8
-
8
-
-
0025675856
-
High efficiency transformation of Escherichia coli with plasmids
-
Inoue H, Nojima H, Okayama H (1990) High efficiency transformation of Escherichia coli with plasmids. Gene 96:23-28
-
(1990)
Gene
, vol.96
, pp. 23-28
-
-
Inoue, H.1
Nojima, H.2
Okayama, H.3
-
9
-
-
33745154819
-
Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2-p53 interaction
-
Ding K, Lu Y, Nikolovska-Coleska Z, Wang G, Qiu S, Shangary S, Gao W, Qin D, Stuckey J, Krajewski K, Roller PP, Wang S (2006) Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2-p53 interaction. J Med Chem 49:3432-3435
-
(2006)
J Med Chem
, vol.49
, pp. 3432-3435
-
-
Ding, K.1
Lu, Y.2
Nikolovska-Coleska, Z.3
Wang, G.4
Qiu, S.5
Shangary, S.6
Gao, W.7
Qin, D.8
Stuckey, J.9
Krajewski, K.10
Roller, P.P.11
Wang, S.12
|