메뉴 건너뛰기




Volumn 19, Issue 1, 2013, Pages 4-27

The Weight of Evidence Does Not Support the Listing of Styrene as "Reasonably Anticipated to be a Human Carcinogen" in NTP's Twelfth Report on Carcinogens

Author keywords

carcinogenicity; metabolism; mode of action; styrene; weight of evidence

Indexed keywords

ANIMALIA; MUS;

EID: 84871911164     PISSN: 10807039     EISSN: 15497860     Source Type: Journal    
DOI: 10.1080/10807039.2012.650577     Document Type: Article
Times cited : (10)

References (54)
  • 1
    • 34248346736 scopus 로고    scopus 로고
    • The non-Hodgkin lymphomas: A review of the epidemiologic literature
    • Alexander, D D, Mink, P JAdami, H O. 2007. The non-Hodgkin lymphomas: A review of the epidemiologic literature. Internat J Cancer, 120(Suppl.12): 1-39.
    • (2007) Internat J Cancer , vol.120 , Issue.SUPPL. 12 , pp. 1-39
    • Alexander, D.D.1    Mink, P.J.2    Adami, H.O.3
  • 2
    • 0031966902 scopus 로고    scopus 로고
    • Cancer incidence among Finnish workers exposed to aromatic hydrocarbons
    • Anttila, A, Pukkala, ERiala, R. 1998. Cancer incidence among Finnish workers exposed to aromatic hydrocarbons. Internat Arch Occup Environ Health, 71: 187-93.
    • (1998) Internat Arch Occup Environ Health , vol.71 , pp. 187-193
    • Anttila, A.1    Pukkala, E.2    Riala, R.3
  • 3
    • 77957176015 scopus 로고
    • Chronic toxicity and three-generation reproduction study of styrene monomer in the drinking water of rats
    • Beliles, R P, Butala, J HStock, C R. 1985. Chronic toxicity and three-generation reproduction study of styrene monomer in the drinking water of rats. Fundam Appl Toxicol, 5: 855-68.
    • (1985) Fundam Appl Toxicol , vol.5 , pp. 855-868
    • Beliles, R.P.1    Butala, J.H.2    Stock, C.R.3
  • 4
    • 74549189369 scopus 로고    scopus 로고
    • Epidemiologic studies of styrene and cancer: A review of the literature
    • Boffetta, P, Adami, H OCole, P. 2009. Epidemiologic studies of styrene and cancer: A review of the literature. J Occup Environ Med, 51(11): 1275-87.
    • (2009) J Occup Environ Med , vol.51 , Issue.11 , pp. 1275-1287
    • Boffetta, P.1    Adami, H.O.2    Cole, P.3
  • 5
    • 0026616009 scopus 로고
    • Mortality among workers engaged in the development or manufacture of styrene-based products - An update
    • Bond, G G, Bodner, K MOlsen, G W. 1992. Mortality among workers engaged in the development or manufacture of styrene-based products - An update. Scand J Work Environ Health, 18: 145-54.
    • (1992) Scand J Work Environ Health , vol.18 , pp. 145-154
    • Bond, G.G.1    Bodner, K.M.2    Olsen, G.W.3
  • 6
    • 0033804464 scopus 로고    scopus 로고
    • Quantification of DNA adducts formed in liver, lungs, and isolated lung cells of rats and mice exposed to 14C-styrene by nose-only inhalation
    • Boogaard, P J, de Kloe, K PWong, B A. 2000. Quantification of DNA adducts formed in liver, lungs, and isolated lung cells of rats and mice exposed to 14C-styrene by nose-only inhalation. Toxicol Sci, 57: 203-16.
    • (2000) Toxicol Sci , vol.57 , pp. 203-216
    • Boogaard, P.J.1    de Kloe, K.P.2    Wong, B.A.3
  • 7
    • 0026698038 scopus 로고
    • A study of tobacco carcinogenesis. XLVII. Bioassays of vinylpyridines for genotoxicity and for tumorigenicity in A/J mice
    • Brunnemann, K D, Rivenson, ACheng, S C. 1992. A study of tobacco carcinogenesis. XLVII. Bioassays of vinylpyridines for genotoxicity and for tumorigenicity in A/J mice. Cancer Lett, 65: 107-13.
    • (1992) Cancer Lett , vol.65 , pp. 107-113
    • Brunnemann, K.D.1    Rivenson, A.2    Cheng, S.C.3
  • 8
    • 0034922020 scopus 로고    scopus 로고
    • Metabolism of the styrene metabolite 4-vinylphenol by rat and mouse liver and lung
    • Carlson, G P, Rivera, A AP and Mantick, N A. 2001. Metabolism of the styrene metabolite 4-vinylphenol by rat and mouse liver and lung. J Toxicol Environ Health, Part A, 63: 541-51.
    • (2001) J Toxicol Environ Health, Part A , vol.63 , pp. 541-551
    • Carlson, G.P.1    Rivera, A.A.2    Mantick, N.A.3
  • 9
    • 0036742013 scopus 로고    scopus 로고
    • 4-Vinylphenol-induced hepatotoxicity and pneumotoxicity in mice
    • Carlson, G P, Ullman, M and Mantick, N A. 2002. 4-Vinylphenol-induced hepatotoxicity and pneumotoxicity in mice. Toxicol Pathol, 30: 565-9.
    • (2002) Toxicol Pathol , vol.30 , pp. 565-569
    • Carlson, G.P.1    Ullman, M.2    Mantick, N.A.3
  • 10
    • 0037200806 scopus 로고    scopus 로고
    • Effect of the inhibition of the metabolism of 4-vinylphenol on its hepatotoxicity and pneumotoxicity in rats and mice
    • Carlson, GP. 2002. Effect of the inhibition of the metabolism of 4-vinylphenol on its hepatotoxicity and pneumotoxicity in rats and mice. Toxicology, 179: 129-36.
    • (2002) Toxicology , vol.179 , pp. 129-136
    • Carlson, G.P.1
  • 11
    • 0023788588 scopus 로고
    • Long-term carcinogenicity bioassays on styrene administered by inhalation, ingestion and injection and styrene oxide administered by ingestion in Sprague-Dawley rats and para-methylstyrene administered by ingestion in Sprague-Dawley rats and Swiss mice
    • Conti, B, Maltoni, CPerino, G. 1988. Long-term carcinogenicity bioassays on styrene administered by inhalation, ingestion and injection and styrene oxide administered by ingestion in Sprague-Dawley rats and para-methylstyrene administered by ingestion in Sprague-Dawley rats and Swiss mice. Ann NY Acad Sci, 534: 203-34.
    • (1988) Ann NY Acad Sci , vol.534 , pp. 203-234
    • Conti, B.1    Maltoni, C.2    Perino, G.3
  • 12
    • 84856215739 scopus 로고    scopus 로고
    • CYP2F2-generated metabolites, not styrene oxide, are a key event mediating the mode of action of styrene-induced lung tumors
    • Cruzan, G, Bus, J SHotchkiss, J. 2011. CYP2F2-generated metabolites, not styrene oxide, are a key event mediating the mode of action of styrene-induced lung tumors. Regul Toxicol Pharmacol, 62: 214-20.
    • (2011) Regul Toxicol Pharmacol , vol.62 , pp. 214-220
    • Cruzan, G.1    Bus, J.S.2    Hotchkiss, J.3
  • 13
    • 0036595023 scopus 로고    scopus 로고
    • Styrene respiratory tract toxicity and mouse lung tumors are mediated by CYP2F-generated metabolites
    • Cruzan, G, Carlson, G PJohnson, K A. 2002. Styrene respiratory tract toxicity and mouse lung tumors are mediated by CYP2F-generated metabolites. Regul Toxicol Pharmacol, 35: 308-19.
    • (2002) Regul Toxicol Pharmacol , vol.35 , pp. 308-319
    • Cruzan, G.1    Carlson, G.P.2    Johnson, K.A.3
  • 14
    • 11244268658 scopus 로고    scopus 로고
    • Ring-oxidized metabolites of styrene contribute to styrene-induced Clara cell toxicity in mice
    • Cruzan, G, Carlson, G PTurner, M. 2005. Ring-oxidized metabolites of styrene contribute to styrene-induced Clara cell toxicity in mice. J Toxicol Environ Health, Part A, 68: 229-37.
    • (2005) J Toxicol Environ Health, Part A , vol.68 , pp. 229-237
    • Cruzan, G.1    Carlson, G.P.2    Turner, M.3
  • 15
    • 26844452279 scopus 로고    scopus 로고
    • Subchronic inhalation studies of styrene in CD rats and CD-1 mice
    • Cruzan, G, Cushman, JAndrews, L A. 1997. Subchronic inhalation studies of styrene in CD rats and CD-1 mice. Fundam Appl Toxicol, 35: 152-65.
    • (1997) Fundam Appl Toxicol , vol.35 , pp. 152-165
    • Cruzan, G.1    Cushman, J.2    Andrews, L.A.3
  • 16
    • 0032416947 scopus 로고    scopus 로고
    • Chronic toxicity/oncogenicity study of styrene in CD rats by inhalation exposure for 104 weeks
    • Cruzan, G, Cushman, JAndrews, L A. 1998. Chronic toxicity/oncogenicity study of styrene in CD rats by inhalation exposure for 104 weeks. Toxicol Sci, 46: 266-81.
    • (1998) Toxicol Sci , vol.46 , pp. 266-281
    • Cruzan, G.1    Cushman, J.2    Andrews, L.A.3
  • 17
    • 0034949436 scopus 로고    scopus 로고
    • Chronic toxicity/oncogenicity study of styrene in CD-1 mice by inhalation exposure for 104 weeks
    • Cruzan, G, Cushman, J RAndrews, L S. 2001. Chronic toxicity/oncogenicity study of styrene in CD-1 mice by inhalation exposure for 104 weeks. J Appl Toxicol, 21: 185-98.
    • (2001) J Appl Toxicol , vol.21 , pp. 185-198
    • Cruzan, G.1    Cushman, J.R.2    Andrews, L.S.3
  • 18
    • 0018253285 scopus 로고
    • Survey of mortality among employees engaged in the manufacture of styrene and polystyrene at the BASF Ludwigshafen works
    • Frentzel-Beyme, R, Thiess, A M and Wieland, R. 1978. Survey of mortality among employees engaged in the manufacture of styrene and polystyrene at the BASF Ludwigshafen works. Scand J Work Environ Health, 4(Suppl 2): 231
    • (1978) Scand J Work Environ Health , vol.4 , Issue.SUPPL. 2 , pp. 231
    • Frentzel-Beyme, R.1    Thiess, A.M.2    Wieland, R.3
  • 19
    • 84871915878 scopus 로고    scopus 로고
    • Comments on the Epidemiology Data Reviewed in the May 22, 2008 NTP Report on Carcinogens Draft Background Document for Styrene
    • Available at
    • Goodman, JE. 2008. "Comments on the Epidemiology Data Reviewed in the May 22, 2008 NTP Report on Carcinogens Draft Background Document for Styrene". Available athttp://ntp.niehs.nih.gove/files/SchweitzerACMA_Styrene508.pdf
    • (2008)
    • Goodman, J.E.1
  • 20
    • 84871871859 scopus 로고    scopus 로고
    • Comments on the Review of Epidemiology Data in the NTP 12th Report on Carcinogens Draft Styrene Profile
    • Available at
    • Goodman, JE. 2009. "Comments on the Review of Epidemiology Data in the NTP 12th Report on Carcinogens Draft Styrene Profile". Available athttp://ntp.niehs.nih.gov/files/20090206Goodman.pdf
    • (2009)
    • Goodman, J.E.1
  • 21
    • 0035979676 scopus 로고    scopus 로고
    • The toxicity of styrene to the nasal epithelium of mice and rats: studies on the mode of action and relevance to humans
    • Green, T, Lee, RToghill, A. 2001a. The toxicity of styrene to the nasal epithelium of mice and rats: studies on the mode of action and relevance to humans. Chem-Biol Interact, 137: 185-202.
    • (2001) Chem-Biol Interact , vol.137 , pp. 185-202
    • Green, T.1    Lee, R.2    Toghill, A.3
  • 22
    • 0035861401 scopus 로고    scopus 로고
    • The role of cytochrome P-450 in styrene induced pulmonary toxicity and carcinogenicity in the mouse
    • Green, T, Toghill, A and Foster, J. 2001b. The role of cytochrome P-450 in styrene induced pulmonary toxicity and carcinogenicity in the mouse. Toxicology, 169: 107-17.
    • (2001) Toxicology , vol.169 , pp. 107-117
    • Green, T.1    Toghill, A.2    Foster, J.3
  • 23
    • 0033947180 scopus 로고    scopus 로고
    • Pulmonary toxicity and carcinogenicity of trichloroethylene: Species differences and modes of action
    • Green, T. 2000. Pulmonary toxicity and carcinogenicity of trichloroethylene: Species differences and modes of action. Environ Health Perspect, 108(Suppl.2): 261-4.
    • (2000) Environ Health Perspect , vol.108 , Issue.SUPPL. 2 , pp. 261-264
    • Green, T.1
  • 24
    • 0021148721 scopus 로고
    • Use of historical control data in carcinogenicity studies in rodents
    • Haseman, J K, Huff, J and Boorman, G A. 1984. Use of historical control data in carcinogenicity studies in rodents. Toxicol Pathol, 12: 126-35.
    • (1984) Toxicol Pathol , vol.12 , pp. 126-135
    • Haseman, J.K.1    Huff, J.2    Boorman, G.A.3
  • 25
    • 0022388377 scopus 로고
    • Mortality of styrene production, polymerization and processing workers at a site in northwest England
    • Hodgson, J T and Jones, R D. 1985. Mortality of styrene production, polymerization and processing workers at a site in northwest England. Scand J Work Environ Health, 1: 347-52.
    • (1985) Scand J Work Environ Health , vol.1 , pp. 347-352
    • Hodgson, J.T.1    Jones, R.D.2
  • 26
    • 0032720864 scopus 로고    scopus 로고
    • Metabolism of styrene by mouse and rat isolated lung cells
    • Hynes, D E, DeNicola, D B and Carlson, G P. 1999. Metabolism of styrene by mouse and rat isolated lung cells. Toxicol Sci, 51: 195-201.
    • (1999) Toxicol Sci , vol.51 , pp. 195-201
    • Hynes, D.E.1    DeNicola, D.B.2    Carlson, G.P.3
  • 28
    • 0004235499 scopus 로고
    • Two-year Chronic Inhalation Toxicity and Carcinogenicity Study on Monomeric Styrene in Rats-Final Report
    • Midland, MI, USA, Midland, MI, USA,: Dow Chemical Company
    • Jersey, G C, Balmer, M FQuast, M F. 1978. "Two-year Chronic Inhalation Toxicity and Carcinogenicity Study on Monomeric Styrene in Rats-Final Report". Midland, MI, USA: Dow Chemical Company.
    • (1978)
    • Jersey, G.C.1    Balmer, M.F.2    Quast, M.F.3
  • 29
    • 0034306056 scopus 로고    scopus 로고
    • Styrene oxide in blood, hemoglobin adducts, and urinary metabolites in human volunteers exposed to C-13(8)-styrene vapors
    • Johanson, G, Ernstgard, LGullstrand, E. 2000. Styrene oxide in blood, hemoglobin adducts, and urinary metabolites in human volunteers exposed to C-13(8)-styrene vapors. Toxicol Appl Pharmacol, 168: 36-49.
    • (2000) Toxicol Appl Pharmacol , vol.168 , pp. 36-49
    • Johanson, G.1    Ernstgard, L.2    Gullstrand, E.3
  • 30
    • 0027828444 scopus 로고
    • Cancer mortality in an international cohort of workers exposed to styrene
    • In: Sorsa M, editors Lyon, France, Lyon,: International Agency for Research on Cancer (IARC) Scientific Publications
    • Kogevinas, M, Ferro, GSaracci, R. 1993. "Cancer mortality in an international cohort of workers exposed to styrene". In Butadiene and Styrene: Assessment of Health Hazards, Edited by: Sorsa, M. 289-300. Lyon, France: International Agency for Research on Cancer (IARC) Scientific Publications.
    • (1993) Butadiene and Styrene: Assessment of Health Hazards , pp. 289-300
    • Kogevinas, M.1    Ferro, G.2    Saracci, R.3
  • 31
    • 0028141384 scopus 로고
    • Cancer mortality in a historical cohort study of workers exposed to styrene
    • Kogevinas, M, Ferro, GAndersen, A. 1994. Cancer mortality in a historical cohort study of workers exposed to styrene. Scand J Work Environ Health, 20: 251-61.
    • (1994) Scand J Work Environ Health , vol.20 , pp. 251-261
    • Kogevinas, M.1    Ferro, G.2    Andersen, A.3
  • 32
    • 0027964219 scopus 로고
    • Incidence of lymphohematopoietic malignancies among styrene-exposed workers of the reinforced plastics industry
    • Kolstad, H A, Lynge, EOlsen, J. 1994. Incidence of lymphohematopoietic malignancies among styrene-exposed workers of the reinforced plastics industry. Scand J Work Environ Health, 20: 272-8.
    • (1994) Scand J Work Environ Health , vol.20 , pp. 272-278
    • Kolstad, H.A.1    Lynge, E.2    Olsen, J.3
  • 33
    • 0029044089 scopus 로고
    • Exposure to styrene and chronic health effects: Mortality and incidence of solid cancers in the Danish reinforced plastics industry
    • Kolstad, H A, Juel, KOlsen, J. 1995. Exposure to styrene and chronic health effects: Mortality and incidence of solid cancers in the Danish reinforced plastics industry. Occup Environ Med, 52: 320-7.
    • (1995) Occup Environ Med , vol.52 , pp. 320-327
    • Kolstad, H.A.1    Juel, K.2    Olsen, J.3
  • 34
    • 0022469749 scopus 로고
    • Rat and mouse forestomach tumors induced by chronic oral administration of styrene oxide
    • Lijinsky, W. 1986. Rat and mouse forestomach tumors induced by chronic oral administration of styrene oxide. J Natl Cancer Inst, 77: 471-6.
    • (1986) J Natl Cancer Inst , vol.77 , pp. 471-476
    • Lijinsky, W.1
  • 35
    • 0032892177 scopus 로고    scopus 로고
    • Lymphatic and haematopoietic cancer mortality in a population attending school adjacent to styrene-butadiene facilities, 1963-1993
    • Loughlin, J E, Rothman, K J and Dreyer, N A. 1999. Lymphatic and haematopoietic cancer mortality in a population attending school adjacent to styrene-butadiene facilities, 1963-1993. J Epidemiol Community Health, 53: 283-7.
    • (1999) J Epidemiol Community Health , vol.53 , pp. 283-287
    • Loughlin, J.E.1    Rothman, K.J.2    Dreyer, N.A.3
  • 36
    • 0017105577 scopus 로고
    • Mortality among rubber workers: Relationship to specific jobs
    • McMichael, A J, Spirtas, RGamble, J F. 1976. Mortality among rubber workers: Relationship to specific jobs. J Occup Med, 18: 178-85.
    • (1976) J Occup Med , vol.18 , pp. 178-185
    • McMichael, A.J.1    Spirtas, R.2    Gamble, J.F.3
  • 37
    • 0038725020 scopus 로고
    • Bioassay of Styrene for Possible Carcinogenicity (CAS No. 100-42-5)
    • NCI (National Cancer Institute), Bethesda, MD, USA, Bethesda, MD,: Carcinogenesis Testing Program
    • NCI (National Cancer Institute). 1979. "Bioassay of Styrene for Possible Carcinogenicity (CAS No. 100-42-5)". NCI-CG-TR-185 Bethesda, MD, USA: Carcinogenesis Testing Program.
    • (1979)
  • 38
    • 0018233718 scopus 로고
    • Mortality experience of styrene-polystyrene polymerization workers. Initial findings
    • Nicholson, W J, Selikoff, I J and Seidman, H. 1978. Mortality experience of styrene-polystyrene polymerization workers. Initial findings. Scand J Work Environ Health, 4(Suppl 2): 247-52.
    • (1978) Scand J Work Environ Health , vol.4 , Issue.SUPPL. 2 , pp. 247-252
    • Nicholson, W.J.1    Selikoff, I.J.2    Seidman, H.3
  • 39
    • 74549203586 scopus 로고    scopus 로고
    • Final Report on Carcinogens Background Document for Styrene
    • NTP (National Toxicology Program), Research Triangle Park, NC, USA, Research Triangle Park, NC, USA,: US Department of Health and Human Services, Public Health Service
    • NTP (National Toxicology Program). 2008. "Final Report on Carcinogens Background Document for Styrene". Research Triangle Park, NC, USA: US Department of Health and Human Services, Public Health Service.
    • (2008)
  • 40
    • 0038032435 scopus 로고    scopus 로고
    • Report on Carcinogens, Twelfth Edition
    • NTP, Research Triangle Park, NC, USA, Research Triangle Park, NC, USA,: US Department of Health and Human Services, Public Health Service
    • NTP. 2011. "Report on Carcinogens, Twelfth Edition". Research Triangle Park, NC, USA: US Department of Health and Human Services, Public Health Service.
    • (2011)
  • 41
    • 0018237850 scopus 로고
    • Effects of long-term oral administration of styrene to mice and rats
    • Ponomarkov, B and Tomatis, L. 1978. Effects of long-term oral administration of styrene to mice and rats. Scand J Work Environ Health, 4: 127-35.
    • (1978) Scand J Work Environ Health , vol.4 , pp. 127-135
    • Ponomarkov, B.1    Tomatis, L.2
  • 42
    • 0021224721 scopus 로고
    • A carcinogenicity study of styrene-7, 8-oxide in rats
    • Ponomarkov, V, Cabral, J RPWahrendorf, J. 1984. A carcinogenicity study of styrene-7, 8-oxide in rats. Cancer Lett, 24: 95-101.
    • (1984) Cancer Lett , vol.24 , pp. 95-101
    • Ponomarkov, V.1    Cabral, J.R.2    Wahrendorf, J.3
  • 43
    • 84871857779 scopus 로고    scopus 로고
    • Comments on the Weight of Evidence Analysis of Epidemiology Data in the May 22, 2008 NTP Report on Carcinogens Draft Background Document for Styrene
    • Available at
    • Rhomberg, LR. 2008. "Comments on the Weight of Evidence Analysis of Epidemiology Data in the May 22, 2008 NTP Report on Carcinogens Draft Background Document for Styrene". Available athttp://ntp.niehs.nih.gov/files/JMcKnightAttachment2.pdf
    • (2008)
    • Rhomberg, L.R.1
  • 44
    • 84871866071 scopus 로고    scopus 로고
    • The Weight of Evidence Does Not Support the NTP Draft Styrene Profile's Conclusion of Reasonably Anticipated to be a Human Carcinogen
    • Available at
    • Rhomberg, LR. 2009. "The Weight of Evidence Does Not Support the NTP Draft Styrene Profile's Conclusion of "Reasonably Anticipated to be a Human Carcinogen. Available athttp://ntp.niehs.nih.gov/files/20090206Rhomberg.pdf
    • (2009)
    • Rhomberg, L.R.1
  • 45
    • 0000599785 scopus 로고
    • Toxicological effects of inhalation exposure to styrene in rats and mice
    • Roycroft, J H, Mast, T JRagan, H A. 1992. Toxicological effects of inhalation exposure to styrene in rats and mice. The Toxicologist, 12: 397
    • (1992) The Toxicologist , vol.12 , pp. 397
    • Roycroft, J.H.1    Mast, T.J.2    Ragan, H.A.3
  • 46
    • 0842288305 scopus 로고    scopus 로고
    • Mortality patterns among workers exposed to styrene in the reinforced plastic boatbuilding industry: An update
    • Ruder, A M, Ward, E MDong, M. 2004. Mortality patterns among workers exposed to styrene in the reinforced plastic boatbuilding industry: An update. Am J Ind Med, 45: 165-76.
    • (2004) Am J Ind Med , vol.45 , pp. 165-176
    • Ruder, A.M.1    Ward, E.M.2    Dong, M.3
  • 47
    • 0036686033 scopus 로고    scopus 로고
    • Physiologically based pharmacokinetic modeling of styrene and styrene oxide respiratory tract dosimetry in rodents and humans
    • Sarangapani, R, Teeguarden, J GCruzan, G. 2002. Physiologically based pharmacokinetic modeling of styrene and styrene oxide respiratory tract dosimetry in rodents and humans. Inhalation Toxicol, 14(8): 789-834.
    • (2002) Inhalation Toxicol , vol.14 , Issue.8 , pp. 789-834
    • Sarangapani, R.1    Teeguarden, J.G.2    Cruzan, G.3
  • 48
    • 28444492685 scopus 로고    scopus 로고
    • An updated study of mortality among North American synthetic rubber industry workers
    • Sathiakumar, N, Graff, JMacaluso, M. 2005. An updated study of mortality among North American synthetic rubber industry workers. Occup Environ Med, 62: 822-9.
    • (2005) Occup Environ Med , vol.62 , pp. 822-829
    • Sathiakumar, N.1    Graff, J.2    Macaluso, M.3
  • 49
    • 84920374919 scopus 로고    scopus 로고
    • Cancer Epidemiology and Prevention (Third Edition)
    • New York, NY, USA, New York, NY, USA,: Oxford University Press
    • Schottenfeld, D and Fraumeni, J F. 2006. "Cancer Epidemiology and Prevention (Third Edition)". New York, NY, USA: Oxford University Press.
    • (2006)
    • Schottenfeld, D.1    Fraumeni, J.F.2
  • 50
    • 84871855247 scopus 로고    scopus 로고
    • Oxidative metabolism of styrene in Cyp2f2-null and Cyp2e1-null mouse liver and lung microsomes
    • Presented at Society of Toxicology 50th Annual Meeting. March
    • Shen, S, Li, LDing, X. 2011. Oxidative metabolism of styrene in Cyp2f2-null and Cyp2e1-null mouse liver and lung microsomes. Toxicologist, 120(Suppl. 2) Presented at Society of Toxicology 50th Annual Meeting. March
    • (2011) Toxicologist , vol.120 , Issue.SUPPL. 2
    • Shen, S.1    Li, L.2    Ding, X.3
  • 51
    • 0030801127 scopus 로고    scopus 로고
    • Evaluation of the metabolism and hepatotoxicity of styrene in F344 rats, B6C3F1 mice, and CD-1 mice following single and repeated inhalation exposures
    • Sumner, S CJ, Cattley, R CAsgharian, B. 1997. Evaluation of the metabolism and hepatotoxicity of styrene in F344 rats, B6C3F1 mice, and CD-1 mice following single and repeated inhalation exposures. Chem-Biol Interact, 106: 47-65.
    • (1997) Chem-Biol Interact , vol.106 , pp. 47-65
    • Sumner, S.C.1    Cattley, R.C.2    Asgharian, B.3
  • 52
    • 3042688750 scopus 로고    scopus 로고
    • Cytogenetic markers, DNA single-strand breaks, urinary metabolites, and DNA repair rates in styrene-exposed lamination workers
    • Vodicka, P, Tuimala, JStetina, R. 2004. Cytogenetic markers, DNA single-strand breaks, urinary metabolites, and DNA repair rates in styrene-exposed lamination workers. Environ Health Perspect, 112: 867-71.
    • (2004) Environ Health Perspect , vol.112 , pp. 867-871
    • Vodicka, P.1    Tuimala, J.2    Stetina, R.3
  • 53
    • 0034988176 scopus 로고    scopus 로고
    • Metabolism of styrene in the human liver in vitro: Interindividual variation and enantioselectivity
    • Wenker, M A, Kezic, SMonster, A C. 2001. Metabolism of styrene in the human liver in vitro: Interindividual variation and enantioselectivity. Xenobiotica, 31(2): 61-72.
    • (2001) Xenobiotica , vol.31 , Issue.2 , pp. 61-72
    • Wenker, M.A.1    Kezic, S.2    Monster, A.C.3
  • 54
    • 0028306731 scopus 로고
    • An updated cohort mortality study of workers exposed to styrene in the reinforced plastics and composites industry
    • Wong, O, Trent, L S and Whorton, M D. 1994. An updated cohort mortality study of workers exposed to styrene in the reinforced plastics and composites industry. Occup Environ Med, 51: 386-96.
    • (1994) Occup Environ Med , vol.51 , pp. 386-396
    • Wong, O.1    Trent, L.S.2    Whorton, M.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.