MicroRNA-181 Regulates CARM1 and Histone Aginine Methylation to Promote Differentiation of Human Embryonic Stem Cells

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Xu, Zhenyu ^a   Jiang, Junfeng ^a   Xu, Chen ^a   Wang, Yue ^a   Sun, Lei ^a   Guo, Xiaocan ^a   Liu, Houqi ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; BONE MORPHOGENETIC PROTEIN 4; CELL PROTEIN; COACTIVATOR ASSOCIATED PROTEIN ARGININE METHYLTRANSFERASE 1; MICRORNA; MICRORNA 181; TRANSCRIPTION FACTOR NANOG; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; EMBRYONIC STEM CELL; HISTONE METHYLATION; HUMAN; HUMAN CELL; PROTEIN DEPLETION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN RNA BINDING; PROTEIN TARGETING; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ARGININE; BONE MORPHOGENETIC PROTEIN 4; CELL DIFFERENTIATION; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC VECTORS; HEK293 CELLS; HISTONES; HOMEODOMAIN PROTEINS; HUMANS; METHYLATION; MICE; MICRORNAS; MICROSCOPY, FLUORESCENCE; PROTEIN-ARGININE N-METHYLTRANSFERASES; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 84871904077     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053146     Document Type: Article

References (50)

1. Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, et al. (2005) Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122: 947-956.
2. Niwa H, Toyooka Y, Shimosato D, Strumpf D, Takahashi K, et al. (2005) Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation. Cell 123: 917-929.
3. Zaehres H, Lensch MW, Daheron L, Stewart SA, Itskovitz-Eldor J, et al. (2005) High-efficiency RNA interference in human embryonic stem cells. Stem Cells 23: 299-305.
4. Fong H, Hohenstein KA, Donovan PJ, (2008) Regulation of self-renewal and pluripotency by Sox2 in human embryonic stem cells. Stem Cells 26: 1931-1938.
5. Ivanova N, Dobrin R, Lu R, Kotenko I, Levorse J, et al. (2006) Dissecting self-renewal in stem cells with RNA interference. Nature 442: 533-538.
6. Orkin SH, Hochedlinger K, (2011) Chromatin connections to pluripotency and cellular reprogramming. Cell 145: 835-850.
7. Bao S, Tang F, Li X, Hayashi K, Gillich A, et al. (2009) Epigenetic reversion of post-implantation epiblast to pluripotent embryonic stem cells. Nature 461: 1292-1295.
8. Gan Q, Yoshida T, McDonald OG, Owens GK, (2007) Concise review: epigenetic mechanisms contribute to pluripotency and cell lineage determination of embryonic stem cells. Stem Cells 25: 2-9.
9. Guenther MG, Frampton GM, Soldner F, Hockemeyer D, Mitalipova M, et al. (2010) Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells. Cell Stem Cell 7: 249-257.
10. Kouzarides T, (2007) Chromatin modifications and their function. Cell 128: 693-705.
11. Eskeland R, Leeb M, Grimes GR, Kress C, Boyle S, et al. (2010) Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination. Mol Cell 38: 452-464.
12. Margueron R, Reinberg D, (2010) Chromatin structure and the inheritance of epigenetic information. Nat Rev Genet 11: 285-296.
13. Torres-Padilla ME, Parfitt DE, Kouzarides T, Zernicka-Goetz M, (2007) Histone arginine methylation regulates pluripotency in the early mouse embryo. Nature 445: 214-218.
14. Wu Q, Bruce AW, Jedrusik A, Ellis PD, Andrews RM, et al. (2009) CARM1 is required in embryonic stem cells to maintain pluripotency and resist differentiation. Stem Cells 27: 2637-2645.
15. Bartel DP, (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
16. Cheung TH, Quach NL, Charville GW, Liu L, Park L, et al. (2012) Maintenance of muscle stem-cell quiescence by microRNA-489. Nature 482: 524-528.
17. Niu Z, Goodyear SM, Rao S, Wu X, Tobias JW, et al. (2011) MicroRNA-21 regulates the self-renewal of mouse spermatogonial stem cells. Proc Natl Acad Sci U S A 108: 12740-12745.
18. He L, Hannon GJ, (2004) MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet 5: 522-531.
19. Wang Y, Keys DN, Au-Young JK, Chen C, (2009) MicroRNAs in embryonic stem cells. J Cell Physiol 218: 251-255.
20. Jain AK, Allton K, Iacovino M, Mahen E, Milczarek RJ, et al. (2012) p53 regulates cell cycle and microRNAs to promote differentiation of human embryonic stem cells. PLoS Biol 10: e1001268.
21. Kane NM, Howard L, Descamps B, Meloni M, McClure J, et al. (2012) Role of microRNAs 99b, 181a, and 181b in the differentiation of human embryonic stem cells to vascular endothelial cells. Stem Cells 30: 643-654.
22. Barroso-delJesus A, Lucena-Aguilar G, Sanchez L, Ligero G, Gutierrez-Aranda I, et al. (2011) The Nodal inhibitor Lefty is negatively modulated by the microRNA miR-302 in human embryonic stem cells. FASEB J 25: 1497-1508.
23. Yamaguchi S, Yamahara K, Homma K, Suzuki S, Fujii S, et al. (2011) The role of microRNA-145 in human embryonic stem cell differentiation into vascular cells. Atherosclerosis 219: 468-474.
24. Morin RD, O'Connor MD, Griffith M, Kuchenbauer F, Delaney A, et al. (2008) Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. Genome Res 18: 610-621.
25. Wu Z, Li H, Rao L, He L, Bao L, et al. (2011) Derivation and characterization of human embryonic stem cell lines from the Chinese population. J Genet Genomics 38: 13-20.
26. Meng X, Neises A, Su RJ, Payne KJ, Ritter L, et al. (2012) Efficient reprogramming of human cord blood CD34+ cells into induced pluripotent stem cells with OCT4 and SOX2 alone. Mol Ther 20: 408-416.
27. Li H, Zhang L, Huang Q, (2009) Differential expression of mitogen-activated protein kinase signaling pathway in the hippocampus of rats exposed to chronic unpredictable stress. Behav Brain Res 205: 32-37.
28. Selvi BR, Batta K, Kishore AH, Mantelingu K, Varier RA, et al. (2010) Identification of a novel inhibitor of coactivator-associated arginine methyltransferase 1 (CARM1)-mediated methylation of histone H3 Arg-17. The Journal of biological chemistry 285: 7143-7152.
29. Hong SH, Rampalli S, Lee JB, McNicol J, Collins T, et al. (2011) Cell fate potential of human pluripotent stem cells is encoded by histone modifications. Cell Stem Cell 9: 24-36.
30. Rugg-Gunn PJ, Cox BJ, Ralston A, Rossant J, (2010) Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo. Proc Natl Acad Sci U S A 107: 10783-10790.
31. Pan G, Tian S, Nie J, Yang C, Ruotti V, et al. (2007) Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells. Cell Stem Cell 1: 299-312.
32. Ang YS, Tsai SY, Lee DF, Monk J, Su J, et al. (2011) Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network. Cell 145: 183-197.
33. Whitcomb SJ, Basu A, Allis CD, Bernstein E, (2007) Polycomb Group proteins: an evolutionary perspective. Trends Genet 23: 494-502.
34. Surface LE, Thornton SR, Boyer LA, (2010) Polycomb group proteins set the stage for early lineage commitment. Cell Stem Cell 7: 288-298.
35. Marson A, Levine SS, Cole MF, Frampton GM, Brambrink T, et al. (2008) Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell 134: 521-533.
36. Chambers I, Silva J, Colby D, Nichols J, Nijmeijer B, et al. (2007) Nanog safeguards pluripotency and mediates germline development. Nature 450: 1230-1234.
37. Fouse SD, Shen Y, Pellegrini M, Cole S, Meissner A, et al. (2008) Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation. Cell Stem Cell 2: 160-169.
38. Wu Z, Yang M, Liu H, Guo H, Wang Y, et al. (2012) Role of nuclear receptor coactivator 3 (ncoa3) in pluripotency maintenance. J Biol Chem 287: 38295-38304.
39. Naeem H, Cheng D, Zhao Q, Underhill C, Tini M, et al. (2007) The activity and stability of the transcriptional coactivator p/CIP/SRC-3 are regulated by CARM1-dependent methylation. Mol Cell Biol 27: 120-134.
40. Han MK, Song EK, Guo Y, Ou X, Mantel C, et al. (2008) SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization. Cell Stem Cell 2: 241-251.
41. Lee YL, Peng Q, Fong SW, Chen AC, Lee KF, et al. (2012) Sirtuin 1 Facilitates Generation of Induced Pluripotent Stem Cells from Mouse Embryonic Fibroblasts through the miR-34a and p53 Pathways. PLoS One 7: e45633.
42. Calvanese V, Lara E, Suarez-Alvarez B, Abu Dawud R, Vazquez-Chantada M, et al. (2010) Sirtuin 1 regulation of developmental genes during differentiation of stem cells. Proc Natl Acad Sci U S A 107: 13736-13741.
43. Judson RL, Babiarz JE, Venere M, Blelloch R, (2009) Embryonic stem cell-specific microRNAs promote induced pluripotency. Nat Biotechnol 27: 459-461.
44. Houbaviy HB, Murray MF, Sharp PA, (2003) Embryonic stem cell-specific MicroRNAs. Dev Cell 5: 351-358.
45. Wang Y, Baskerville S, Shenoy A, Babiarz JE, Baehner L, et al. (2008) Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation. Nat Genet 40: 1478-1483.
46. Li X, Zhang J, Gao L, McClellan S, Finan MA, et al. (2012) MiR-181 mediates cell differentiation by interrupting the Lin28 and let-7 feedback circuit. Cell Death Differ 19: 378-386.
47. Naguibneva I, Ameyar-Zazoua M, Polesskaya A, Ait-Si-Ali S, Groisman R, et al. (2006) The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation. Nat Cell Biol 8: 278-284.
48. Kazenwadel J, Michael MZ, Harvey NL, (2010) Prox1 expression is negatively regulated by miR-181 in endothelial cells. Blood 116: 2395-2401.
49. Ji J, Yamashita T, Budhu A, Forgues M, Jia HL, et al. (2009) Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells. Hepatology 50: 472-480.
50. O'Loghlen A, Munoz-Cabello AM, Gaspar-Maia A, Wu HA, Banito A, et al. (2012) MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation. Cell Stem Cell 10: 33-46.