Quinacrine Impairs Enterovirus 71 RNA Replication by Preventing Binding of Polypyrimidine-Tract Binding Protein with Internal Ribosome Entry Sites

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Wang, Jianmin ^a   Du, Jiang ^a   Wu, Zhiqiang ^a   Jin, Qi ^a  

^a INSTITUTE OF PATHOGEN BIOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MEPACRINE; MESSENGER RNA; POLYPYRIMIDINE TRACT BINDING PROTEIN; PROTEIN VP1; VIRUS RNA;

ANTIVIRAL ACTIVITY; ARTICLE; CELL CULTURE; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; COXSACKIE VIRUS; DRUG EFFECT; ECHO VIRUS; ENTEROVIRUS 71; GROWTH INHIBITION; IC 50; INTERNAL RIBOSOME ENTRY SITE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN RNA BINDING; PROTEIN SYNTHESIS INHIBITION; RNA REPLICATION; VIRUS ENTRY; VIRUS REPLICATION;

ANTINEOPLASTIC AGENTS; ANTIVIRAL AGENTS; CELL LINE, TUMOR; ENTEROVIRUS A, HUMAN; ENTEROVIRUS INFECTIONS; HUMANS; INHIBITORY CONCENTRATION 50; PLASMIDS; POLYPYRIMIDINE TRACT-BINDING PROTEIN; QUINACRINE; RHABDOMYOSARCOMA; RIBOSOMES; RNA, SMALL INTERFERING; RNA, VIRAL;

ECHOVIRUS; ENCEPHALOMYOCARDITIS VIRUS; ENTEROVIRUS; HUMAN ENTEROVIRUS 71; MIRIDAE; POLIOVIRUS;

EID: 84871886753     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0052954     Document Type: Article

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