A novel cell-based assay for G-protein-coupled receptor-mediated cyclic adenosine monophosphate response element binding protein phosphorylation

Journal of Biomolecular Screening

Volumn 11, Issue 4, 2006, Pages 351-358

  Selkirk, Julie V ^a   Nottebaum, Lisa M ^a   Ford, Ian C ^a   Santos, Mark ^a   Malany, Siobhan ^a   Foster, Alan C ^a   Lechner, Sandra M ^a  

^a NEUROCRINE BIOSCIENCES INC   (United States)

Author keywords

Adenosine2A receptor; CREB; In cell Western; Odyssey ; Phosphorylation

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 4 [2 [7 AMINO 2 (2 FURYL) 1,2,4 TRIAZOLO[2,3 A][1,3,5]TRIAZIN 5 YLAMINO]ETHYL]PHENOL; 5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; 9 CHLORO 2 (2 FURYL) 5,6 DIHYDRO 5 IMINO 1,2,4 TRIAZOLO[2,3 C]QUINAZOLINE; ADENOSINE RECEPTOR; ADENOSINE RECEPTOR BLOCKING AGENT; ADENOSINE RECEPTOR STIMULATING AGENT; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; G PROTEIN COUPLED RECEPTOR; MELANOCORTIN 4 RECEPTOR; RADIOLIGAND; ROLIPRAM;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG RESEARCH; EMBRYO; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IMAGING SYSTEM; INFRARED RADIATION; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; SCREENING; STATISTICAL ANALYSIS;

ADENOSINE; ANIMALS; BLOTTING, WESTERN; CELL LINE; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DRUG EVALUATION, PRECLINICAL; HUMANS; INFRARED RAYS; PC12 CELLS; PHENETHYLAMINES; PHOSPHORYLATION; RADIOLIGAND ASSAY; RATS; RECEPTOR, MELANOCORTIN, TYPE 4; RECEPTORS, ADENOSINE A2; RECEPTORS, G-PROTEIN-COUPLED; RECOMBINANT PROTEINS;

EID: 33744937948     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057106286608     Document Type: Article

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