AMP kinase activation improves angiogenesis in pulmonary artery endothelial cells with in utero pulmonary hypertension

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 304, Issue 1, 2013, Pages

  Teng, Ru Jeng ^a   Du, Jianhai ^b   Afolayan, Adeleye J ^a   Eis, Annie ^a   Shi, Yang ^c   Konduri, Girija G ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c AURORA HEALTH CARE   (United States)

Author keywords

Endothelial nitric oxide synthase; Metformin; MnSOD; Persistent pulmonary hypertension of the newborn; Vascular endothelial growth factor

Indexed keywords

CAVEOLIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ACTIVATOR; MANGANESE SUPEROXIDE DISMUTASE; METFORMIN; PHOSPHOPROTEIN PHOSPHATASE 2; PLATELET DERIVED GROWTH FACTOR B; SERINE; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL FUNCTION; CELL GROWTH; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; IN VITRO STUDY; LUNG ARTERY; LUNG ENDOTHELIUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; PULMONARY HYPERTENSION; SIGNAL TRANSDUCTION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CAVEOLIN 1; CELLS, CULTURED; ENDOTHELIAL CELLS; ENZYME ACTIVATION; HYPERTENSION, PULMONARY; METFORMIN; NEOVASCULARIZATION, PHYSIOLOGIC; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; PULMONARY ARTERY; PYRAZOLES; PYRIMIDINES; REACTIVE OXYGEN SPECIES; SHEEP, DOMESTIC; SUPEROXIDE DISMUTASE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84871870815     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00200.2012     Document Type: Article

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