Increasing viral dose causes a reversal in CD8+ T cell immunodominance during primary influenza infection due to differences in antigen presentation, T cell avidity, and precursor numbers

Journal of Immunology

Volumn 190, Issue 1, 2013, Pages 36-47

  Luciani, Fabio ^a   Sanders, Megan T ^b   Oveissi, Sara ^b   Pang, Ken C ^b,c   Chen, Weisan ^b,d  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b AUSTIN HOSPITAL   (Australia)

^c WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d LA TROBE UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ANTIGEN SPECIFICITY; ARTICLE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; EMBRYO; FEMALE; INFLUENZA A; INFLUENZA VIRUS A; LYMPHOCYTE COUNT; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGEN PRESENTATION; CD8-POSITIVE T-LYMPHOCYTES; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; FEMALE; HUMANS; IMMUNODOMINANT EPITOPES; INFLUENZA A VIRUS; INFLUENZA, HUMAN; LYMPHOCYTE COUNT; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MADIN DARBY CANINE KIDNEY CELLS; MICE; MICE, INBRED C57BL; MODELS, IMMUNOLOGICAL; PEPTIDES; STEM CELLS; T-LYMPHOCYTE SUBSETS; VIRAL LOAD;

EID: 84871846196     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1200089     Document Type: Article

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